OHSU Digital Collections (Oregon Health and Science University)
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A multi-model approach for examining cross-reactive antibody-mediated alphavirus immunity following infection and vaccination
No full textThis dissertation characterizes cross-reactive immunity to emerging alpahviruses such as chikungunya virus in the context of infection or vaccination, in various models
Comparison of the health needs of homeless men and homeless women in Portland, Oregon
No full textIn the last 20 years, homelessness in America has become a social problem of great magnitude. Despite extensive research on the topic, many questions regarding persons who are homeless remain unanswered. The purpose of this study is to explore the health status, health practices, and health care needs and experiences of homeless men in Portland, Oregon
Graph-based multimodal integration for breast cancer molecular subtype classification
No full textPatient stratification is essential for addressing breast cancer's inter- and intra-heterogeneity. While the PAM50 classifier is widely regarded to be the gold standard for breast cancer molecular subtyping, there are challenges associated with this method including high costs and potential delays in treatment delivery.
To address these challenges, we implemented a graph-based multimodal model that integrates histopathology whole slide images and bulk RNA sequencing data. This approach assesses whether we can use histopathology slide images alone (or in combination with other modalities) to improve the clinical utility of molecular subtyping. By incorporating RNA sequencing, the model identifies a minimal gene set that can be used in addition to image analysis for molecular subtyping. By doing so, we can evaluate whether multimodal approaches can enhance the efficiency and accessibility of breast cancer treatment delivery
Faces
No full textThis project depicts and explores power dynamics in healthcare. Specifics: 9x12; Marker, pen, colored pencil, pastels, stamps and ink, acrylic paint. This project was created as part of Narrative Competence for Health Professionals, an interprofessional education course. </p
