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Infant growth among twins: patterns, drivers, and effects in a cohort with high representation of systematically underserved and marginalized communities, 2005-2021
Get PDFThe prevalence of twin pregnancies has growth rapidly in the past several decades, driven largely by increased use of assisted reproductive technologies and older maternal age. However, epidemiologic and clinical evidence focused specifically on twin pregnancies and children remains scant. Early childhood weight trajectory has been studied extensively among singleton children, with results largely supporting an association with numerous downstream health outcomes including overweight and obesity in childhood and adulthood. Minimal evidence in this topic exists for twin children. In this dissertation, I explore normal early childhood weight trajectory and its association with gestational weight gain and with childhood body mass index in twins compared to singletons
Marunggay activity: gathering student input to advance the School of Public Health's antiracism initiative
Get PDFIn 2020, the School of Public Health declared its commitment to becoming an antiracist institution. Student feedback is necessary for holding the institution accountable for its commitment to advancing antiracism; however, low response rates to traditional surveys have led us to explore innovative ways to collect student input. This activity aims to identify student interests, goals and needs to further the SPH's commitment to becoming an antiracist institution
Normal saline and lactated ringers for sepsis fluid resuscitation in oncology patients
Get PDFThis quality improvement project was conducted to evaluate types of fluid resuscitation in septic oncology patients and to compare the difference in patients’ outcomes with different types of fluid
Functional effort correction of the lungs in radiation therapy longitudinal studies
No full textAn effort correction technique for longitudinal lung studies using four-dimensional computed tomography is described. This new technique focuses on nondamaged regions and prediction of biomarkers
Analyzing clinical resources for serving patients with pediatric obesity and metabolic syndrome
Get PDFThe Pediatric Gastroenterology department at Oregon Health & Science University (OHSU) has a need to address the current resource allocations given to patients dealing with pediatric obesity and other comorbidities. Pediatric metabolic syndrome and obesity management is a growing concern for children. The consequences of children not managing this health concern with proper nutrition, physical activity, and support from family can result in chronic conditions. This research serves as an exploration into how the pediatric clinics are currently structured. The recommendations show how improvements can contribute to better health outcomes in pediatric obesity patients. The objective is to align OHSU pediatric obesity serving clinics within to the institutions commitment
to provide the highest quality patient and family centered care. By adding or expanding resources offered to children, this research aims to enhance children's health outcomes through improved clinical workflows, referral processes, parent support programs, and addressing the lack of social determinants of health primarily through food insecurity
The role of nucleus accumbens dopamine in incubation of cocaine craving
Get PDFThe nucleus accumbens plays a key role in guiding motivated behavior by integrating glutamate inputs, the major driver of neuronal activation, and dopamine (DA) inputs, a critical source of neuronal modulation. Therefore, it is important to understand how glutamate and DA transmission interact, particularly in reward-seeking behavior. Substance use disorder (SUD) is a brain disease in which reward-seeking becomes dysregulated. In this dissertation, I use fiber photometry to extend our understanding of this interaction during two reward-seeking tasks