USU-IR Repositori Institusi Universitas Sumatera Utara
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The Potential of Biocomposite Nano Chitosan-Silica-Calcium Carbonate as an Agent of Guided Tissue Remineralization (GTR) Dentin
No full textRemineralisasi dentin merupakan pendekatan minimal invasif untuk mengembalikan struktur dan fungsi dentin yang mengalami demineralisasi, terutama pada karies dentin yang dalam. Salah satu strategi remineralisasi terkini adalah Guided Tissue Remineralization (GTR), yang meniru proses biomineralisasi alami melalui pendekatan bottom-up dengan bantuan analog protein non-kolagen. Penelitian ini bertujuan untuk mengembangkan dan mengevaluasi potensi biokomposit nano yang terdiri dari kitosan, silika, dan kalsium karbonat sebagai agen GTR. Metode: Biokomposit disintesis melalui proses pencampuran dan modifikasi bahan, kemudian dikarakterisasi menggunakan XRD, TEM, uji setting time, dan ketahanan kompresi. Hasil: Aplikasinya pada dentin yang telah didemineralisasi selama 14 hari menunjukkan keberhasilan remineralisasi baik secara ekstrafilbrilar maupun intrafilbrilar. Hasil uji statistik menunjukkan bahwa biokomposit memiliki performa remineralisasi yang signifikan dibandingkan kontrol positif (Biodentine), serta memperlihatkan karakteristik fisikokimia yang mendukung sebagai bahan remineralisasi. Kesimpulan dari penelitian ini menyatakan bahwa biokomposit Nano-Chitosan-Silika-Kalsium Karbonat (nKSC) berpotensi tinggi sebagai agen GTR dentin yang efektif dan berkelanjutan.157 PagesTesis Magiste
Professional Work Practice of Industrial Pharmacists at PT Kalbio Global Medika Cikarang
No full textBackground: The pharmaceutical industry plays a strategic role in ensuring the
availability of safe, effective, and high-quality medicines in accordance with
regulatory standards. To achieve this, the implementation of Good Manufacturing
Practice (GMP) is a fundamental requirement in every stage of production.
Pharmacists, as pharmaceutical professionals, hold a crucial responsibility in
ensuring that all processes within the pharmaceutical industry comply with GMP
principles, from raw material procurement to finished product distribution.
Therefore, practical understanding and hands-on experience are essential through
the pharmacist’s professional work practice in the pharmaceutical industry.
Objective: The pharmacist’s practice at PT Kalbio Global Medika was carried out
to broaden knowledge and understanding of the roles, functions, and
responsibilities of pharmacists in the pharmaceutical industry, particularly in the
areas of production, quality assurance, and quality control through the
implementation of GMP standards.
Summary: The pharmacist’s practice was conducted from February 3 to March 28,
2025, at PT Kalbio Global Medika, a biopharmaceutical company focusing on the
development and production of biological medicines with modern facilities
compliant with GMP standards. During the practice, observations and in-depth
learning were carried out regarding the quality management system, production
facilities, personnel, and documentation supporting regulatory compliance. In
addition, a cleaning validation protocol was developed as part of the application of
GMP principles in the pharmaceutical industry setting. Overall, the pharmacist’s
practice provided a comprehensive overview of pharmaceutical practice in the
industry and emphasized the pharmacist’s role in ensuring product quality.
Conclusion: The pharmacist’s practice at PT Kalbio Global Medika provided
practical experience and a deeper understanding of GMP implementation in the
pharmaceutical industry. This practice highlighted the strategic role of pharmacists
as those responsible for production, quality control, and quality assurance in
supporting the availability of safe, high-quality, and compliant pharmaceutical
products.115 PagesKarya Tulis Profes
The Role Of The E-Parking System in Revenue The Public Roadside Parking Retribution Of Medan City
No full textMedan City faces challenges in managing public roadside parking which has an impact on low parking retribution revenues. To overcome this, the Medan City Government launched the E-Parking system to increase efficiency and transparency in managing parking fees.
This research aims to analyze the role of the E-Parking system in increasing revenue from public roadside parking retribution, as well as exploring the obstacles faced in implementing this system, including the use of barcodes in subscription parking.
This research uses a descriptive qualitative approach with data collection techniques through interviews and documentation.
The research results show that E-Parking plays an important role in increasing parking retributionrevenues, reducing dependence on manual systems, and encouraging parking user compliance. Obstacles faced include naughty parking attendants, limited means of payment, and lack of socialization. Parking retribution revenues show a positive trend, although there will be a decline in 2024. E-Parking systems and subscription parking contribute significantly to regional income.120 PagesKertas Karya Diplom
The Effect of Addition Pineapple Juice (Ananas comosus L. Merr) and Heating Time on the Quality of Ginger Syrup (Zingiber officinale)
No full textThis study was aimed to determine the effect of addition pineapple juice and
heating time and the interaction between the two factors on the quality
characteristics of ginger syrup. This research was conducted using a factorial
Complete Randomized Design (CRD) method with 2 factors, namely addition of
pineapple juice (S): (S1 = 20%, S2 = 40%, S3 = 60%) and the heating time (W): (W1
= 5 minutes, W2 = 10 minutes, W3 = 15 minutes). The parameters tested in this
study were total soluble solids, pH, total sugars, antioxidant activity, viscosity, total
acid, and organoleptic tests (color, aroma, taste, and general acceptance).
The results showed that the addition pineapple juice had a highly significant
effect (P<0,01) on the parameters of pH, total sugars, viscosity, antioxidant activity,
total soluble solids, total acid, and organoleptic tests (color, aroma, taste, and
general acceptance). The heating time had a highly significant effect (P<0,01) on
the parameters pH, viscosity, antioxidant activity, total soluble solids and general
acceptance also had no significant effect (P>0,05) on the parameters of total
sugars, total acid, and organoleptic test (color, aroma, taste). The interaction
between two factors had a highly significant effect (P<0,01) on the parameters of
pH, antioxidant activity and had a significant effect (P<0,05) on the parameters of
viscosity, total soluble solids and general acceptance, had no significant effect
(P>0,05) on the parameters of total sugars, total acid, and organoleptic test (color,
aroma, taste). The best treatment obtained through De Garmo method was the
addition of 60% pineapple juice with a heating time of 5 minutes (S3W1).112 PagesSkripsi Sarjan
The Legal Validity of Unwritten Profit-Sharing Agreements (A Case Study of Ananda Tempe Factory)
No full textProduction sharing agreement is a form of agreement that is widely applied in various business sectors in Indonesia, including in the tempe manufacturing industry which is generally still small to medium scale. In practice, many tempe factories, such as Tempe Ananda Factory, use unwritten profit- sharing agreements. However, the absence of formal documents in unwritten profit-sharing agreements can lead to various legal problems, especially when there is a dispute regarding the distribution of profits and responsibilities of each party. The research objectives in this thesis are to explain the unwritten profit- sharing agreement applied by Ananda Tempe Factory in accordance with the applicable legislation, to find out the obstacles in conducting an unwritten profit- sharing agreement at Ananda Tempe Factory, to find out the form of settlement in the event of default in the implementation of an unwritten profit-sharing agreement at Ananda Tempe Factory. The research method used is juridical-normative supported by field research. The nature of the research used is descriptive research. With the type of data used is secondary and tertiary data related to the problem under study. The results showed that although unwritten agreements are recognized in the Indonesian legal system as stipulated in Article 1320 of the Civil Code, these agreements will still be faced with high risks in terms of proof when a dispute occurs. Oral agreements or unwritten agreements are difficult to prove in court, so they often result in prolonged conflicts. In addition, unwritten profit-sharing agreements can also hinder business growth due to a lack of legal certainty, which can affect the confidence of potential business partners and investors.101 pagesSkripsi Sarjan
Smart Electric Waste Transport Vehicle Monitoring System Design
No full textWaste is an unavoidable issue in daily life. Almost every human activity generates
waste, thus requiring an efficient management system, especially for garbage collection
vehicles. In Indonesia, garbage trucks generally still rely on fossil fuels and are not yet
equipped with intelligent monitoring systems. This study aims to design and implement an
intelligent monitoring system for electric garbage trucks based on the Internet of Things
(IoT). The system utilizes an ESP32 microcontroller integrated with an HC-SR04
ultrasonic sensor to measure waste height, an S-type load cell to measure waste weight,
and a Neo-6M GPS module for vehicle tracking. Data is transmitted to the ThingsBoard
platform using the MQTT protocol in JSON format every 3 seconds and displayed through
a driver dashboard. The test results show that the system successfully measures and
transmits data on waste height, weight, and vehicle location in real time. The ultrasonic
sensor provides reasonably accurate level estimates, while the S-type load cell produces
varying accuracy levels depending on the weight distribution inside the truck bed. In the
evenly distributed load scenario, the sensor achieved very high accuracy with an average
of 99.65%, showing an upward trend as the load increased. When the load was
concentrated in the center, accuracy remained high at 97.57%, indicating that a centrally
placed sensor works optimally when the force is applied directly above it. However, when
the load was focused at the front and rear ends, the accuracy dropped significantly to
58.07% and 2.5%, respectively. This decrease is attributed to the hydraulic chassis
structure obstructing the transfer of force from the load to the sensor, particularly when
the weight is far from the sensor's position. Tests on the left and right sides resulted in
average accuracies of 88.64% and 82.95%, respectively, with a decreasing trend as the
load increased. Overall, placing the sensor in the center is effective for symmetrical or
centered loads but less ideal for uneven load distribution. Therefore, implementing
multiple sensors in strategic positions is recommended to enhance system accuracy.
Meanwhile, vehicle location monitoring using the Neo-6M GPS module worked effectively,
showing minimal deviation when compared to the Garmin eTrex 10 reference device, with
nearly 100% accuracy. In conclusion, the system enables efficient and real-time monitoring
of electric garbage trucks and has the potential to support smarter and more integrated
waste management solutions.87 PagesSkripsi Sarjan
Architectural Design of Wisma Kolaborasi Building in Medan City
No full textMedan City, as a center of economic growth and the creative industry, requires collaborative spaces capable of accommodating the activities of communities, startups, and creative industry actors. The limited availability of representative and flexible coworking spaces poses a challenge in supporting the development of a thriving and inclusive creative ecosystem. Wisma Kolaborasi Kota Medan is designed as an adaptive, functional, and sustainable architectural solution. The design approach focuses on spatial flexibility to accommodate various user needs—ranging from individual work, group collaboration, to community activities—while prioritizing comfort and efficiency. The architectural concept draws inspiration from the kantan flower (Medinilla speciosa), a native flora of North Sumatra that symbolizes growth, local elegance, and harmony with nature. These values are embodied in the building’s massing, which resembles blooming petals, as well as in vertical elements serving as sun shading that reflect the natural structure of the flower. The design also incorporates leaf-inspired forms as symbols of regeneration and ecological harmony, expressed through an organic façade and dynamic structural elements. Building materials are selected based on sustainability principles, including the use of local resources, recycled materials, and environmentally friendly construction systems. Wisma Kolaborasi is envisioned to become an urban architectural icon that supports the growth of creative communities and promotes sustainable, locally driven development in Medan.554 PagesTesi
The Effect of Organizational Commitment and Work Culture on Employee Satisfaction (Case Study of PT. Telkom Indonesia Witel Sumut)
No full textRealizing the importance of human resource management (HR) in achieving organizational goals, companies and leaders need to increase their attention to their employees in an effort to increase organizational commitment. HR management was created to establish a viable corporate culture, and include programs that reflect and support the core values of the company and ensure its success.
This research aims to analyze the influence of organizational commitment and work culture on employee job satisfaction. The influence of organizational commitment and work culture will be analyzed partially and simultaneously on employee job satisfaction.
The form of research used in this research is quantitative research with an associative approach. Sampling was carried out through a saturated sampling technique with 35 respondents as samples. The primary data used in this study were obtained by distributing questionnaires directly while skunder data were obtained through literature studies. The data analysis methods used are validity test, reliability test, classical assumption test, multiple linear regression test, and hypothesis test.
The results of the research conducted show that the variables organizational commitment (X1) and work culture (X2) have a significant effect on employee job satisfaction (Y) and all independent variables simultaneously (simultaneously) influence employee job satisfaction (Y). The determinant coefficient test shows that there is a fairly close relationship between organizational commitment (X1) and work culture (X2) on employee job satisfaction with an R value of 0.713. Through the adjusted R square value, it is also known that the variables between organizational commitment (X1) and work culture (X2) contribute 47,8% to the employee job satisfaction variable while the remaining 52,2% is influenced by other variables not discussed in this research.142 PagesSkripsi Sarjan
Potential for Developing Cattle Farming Business in the Buffer Zone of Mount Leuser National Park, Bahorok District
No full textLocal communities in Bahorok District are highly dependent on the agricultural and livestock sectors as their main livelihoods, with the environment and abundant natural resources, it is very profitable for the community to raise livestock. The type of data used in this study is primary data obtained through observation and interviews and secondary data through literature and the North Sumatra Central Statistics Agency. Determination of the sample by Purposive Sampling with 100 cattle breeders. Data analysis was carried out by calculating income, financial analysis of Net Present Value (NPV), Net Benefit-Cost (B/C), Payback Period (PP), and economic analysis. The results of this study indicate that the average income of cattle breeders in the Buffer Zone of Gunung Leuser National Park, Bahorok District is IDR 24,551,421 for semi-intensive and IDR 8,235,155 for extensive per year. The income of breeders can cover production costs so that income is positive or profitable. The cattle farming business shows that by using an interest rate of 8%, the NPV is obtained >0 or has a positive value, the Gross B/C value is obtained 1.97 and the Net B/C value is 1.25, meaning BCR>1 means a positive value, the PP value is 3.1 and 4.2 years, and the economic analysis shows that the cattle farming business has an important role in the economy in Bahorok District.87 pagesSkripsi Sarjan
The Effect of Butterfly Pea Flower (Clitoria ternatea) as Drinking Water on Broiler Chicken Performance
No full textButterfly pea flower is one of the ingredients that contains natural antioxidants. Flavonoid compounds in butterfly pea flowers can be used as natural antioxidants that neutralize free radicals that attack body cells that can affect the performance of broiler chickens. This study aims to determine the effect of giving boiled butterfly pea flower water (Clitoria ternatea) as drinking water on Performance (weight gain, feed consumption, and feed conversion) in broiler chickens. The study was conducted in a research cage located at Jl. Besar Delitua Gg. Cempaka No.42C. This study was conducted for 1 month and was carried out from March to April 2024. This study used a Completely Randomized Design (CRD) consisting of 5 treatments and 4 replications. The treatments consisted of P0 = control; P1 = 15 ml / liter; P2 = 30 ml / liter; P3 = 45 ml / liter; P4 = 60 ml / liter. The variables observed were feed consumption, body weight gain, and feed conversion. The results of the study showed that the provision of blue pea flower infusion as drinking water for broiler chickens had a highly significant effect (P 0.05) on feed conversion ratio. From the results of the study obtained, it can be concluded that the best treatment in this study was P4, namely with a treatment level of 60 ml / liter.56 PagesSkripsi Sarjan