Medico Research Chronicles
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A Case of Long-standing Atopic Skin Successfully Treated through Constitutional Homeopathy at Dr Batra’s
No full textA 17-year-old girl, residing in Qatar, presented with a 4–5 year history of chronic perioral dermatitis associated with dry, cracked, and bleeding skin around the mouth, extending to the neck and upper chest. Multiple topical steroid creams had given temporary relief. The condition worsened after an episode of conjunctivitis treated with allopathic medicines, leading to severe flare-up. A detailed constitutional homeopathic approach focusing on her physical generals, temperament, and stress-handling pattern led to complete and sustained remission within 12 months, with no recurrence for over 8 months even under climatic stress
Clinical Characteristics and Outcomes of Diabetic Ketoacidosis in School-Age Children: A Single-Center Analysis of 60 Cases
Full text linkBackground: Diabetic ketoacidosis (DKA) remains a significant complication in pediatric diabetes, yet specific data focusing on school-age children is limited. This study analyzed the clinical characteristics and outcomes of DKA in this distinct age group to enhance our understanding and improve management strategies.
Methods: We conducted a retrospective analysis of 60 cases of DKA in children aged 6-12 years admitted to our tertiary care center between January 2022 and December 2023. Clinical characteristics, laboratory parameters, treatment outcomes, and complications were evaluated. DKA severity was classified according to venous pH values, and outcomes were analyzed using standardized protocols based on ISPAD guidelines.
Results: The study included 60 patients (mean age 9.3 ± 2.1 years, 56.7% female), with 31.7% being newly diagnosed cases. DKA severity distribution showed 36.7% mild, 41.7% moderate, and 21.6% severe cases. The median time to DKA resolution was 16.8 hours (IQR: 12.4-22.6), with a mean hospital stay of 3.2 ± 1.4 days. Complications occurred in 13.3% of cases, including cerebral edema (3.3%), hypokalemia (6.7%), and hypoglycemia (3.3%). Among established diabetes cases, insulin omission (46.3%) and technical insulin pump issues (14.6%) were the primary precipitating factors. Multivariate analysis identified severe initial acidosis (pH <7.1) as a significant predictor of prolonged DKA resolution (adjusted OR 2.9, 95% CI 1.3-6.5).
Conclusions: Our findings reveal distinct patterns of DKA presentation and outcomes in school-age children, with notably lower rates of severe cases and complications compared to general pediatric populations. The emergence of insulin pump-related issues as a significant precipitating factor highlights the need for enhanced technical support and education programs. These results support the development of age-specific management protocols and preventive strategies for DKA in school-age children
Aesthetic and functional rehabilitation of a mutilated dentition with dental Implants: A Case Report : Aesthetic and functional rehabilitation of a mutilated dentition with dental Implants: A Case Report
No full textDental implants are gaining popularity as the treatment of choice for the replacement of missing teeth due to their high predictability, long-term success, and ability to restore both function and esthetics. Over the past decades, implants have been utilized not only for the replacement of a single missing tooth but also for partial edentulism, and more extensively for the rehabilitation of completely edentulous arches using implant-supported prostheses. Conventional removable dentures, though widely used, often fail to provide adequate retention, stability, and chewing efficiency, especially in patients with advanced ridge resorption, leading to patient dissatisfaction and compromised quality of life. Implant-supported fixed dentures, such as those based on the All-on-4 concept, overcome these limitations by providing a stable, fixed, and functionally superior alternative. This case report presents the full-mouth rehabilitation of a completely edentulous patient using the All-on-4 concept in both the maxillary and mandibular arches. The treatment was carefully planned and executed to restore oral function, esthetics, phonetics, and overall patient comfort, while minimizing surgical morbidity, reducing treatment duration, and controlling cost. A successful outcome was achieved with the delivery of a definitive screw-retained hybrid prosthesis, resulting in improved mastication, facial profile, and patient satisfaction.
 
Homeopathic Case Report: Management of Bilateral Ovarian Cysts with Hydrosalphinx
No full textA 41-year-old female, diagnosed with bilateral ovarian cysts with hydrosalpinx, presented with complaints of pain and bloatedness in the abdomen, along with emotional stress due to marital discord and her husband’s alcoholism. Despite several courses of allopathic medication, her symptoms persisted. A detailed homeopathic constitutional approach was undertaken, focusing on both physical and emotional aspects. The patient showed marked improvement in her physical symptoms and mental well-being, along with radiological normalization of ovarian structures
Pharmacy vs. Doping: Educating for a Cleaner Sport
Full text linkFrom a legal standpoint, doping refers to the use of prohibited substances or methods by athletes to enhance performance, which is illegal under national and international laws governing sports A major public health concern, doping in sports is on the rise and becoming more complex, using physiological, mechanical, and pharmaceutical methods. In the context of sports, doping is defined as the use of performance-enhancing drugs (PEDs) or other banned substances and methods by athletes to gain an unfair advantage in competition. Combating doping is an important responsibility of pharmacy practitioners. Although most in the pharmaceutical sector are in favor of outlawing performance-enhancing drugs from athletic competition, more specific training on anti-doping and doping is necessary.
The average pharmacist\u27s knowledge score on the illegal status of pharmaceuticals is 53.2%, (according to a survey in Qatar) and their understanding of doping and anti-doping is minimal. Around half of the students in India had some ideas of which medications are illegal for athletes to consume. The knowledge level of pharmacy students is modest. Statements against doping in sports were also met with unfavorable views from them.
The purpose of this research was to examine the pharmaceutical industry\u27s involvement in anti-doping medications and the pharmacists\u27 understanding, perspective, and behavior about doping in athletic competition
Surgical Management of Congenital Diaphragmatic Hernia in Newborn
Full text linkBackground: Congenital diaphragmatic hernia (CDH) is a life-threatening condition in newborns that requires prompt surgical intervention. This study aims to evaluate the outcomes of surgical management of CDH in newborns, focusing on survival rates, complications, and long-term prognosis.
Objectives: To assess the survival rate of newborns with congenital diaphragmatic hernia (CDH) who undergo surgical management.
Methods: This retrospective study was conducted at Dhaka Shishu Hospital from 2021 to 2023, involving 57 newborns diagnosed with CDH who underwent surgical repair. Preoperative stabilization, surgical techniques, postoperative care, and complications were documented. The primary outcome was survival rate, while secondary outcomes included the incidence of postoperative complications, duration of mechanical ventilation, and overall hospital stay
Result: Among the 57 newborns, among them 56.1% male and 43.8% are female. Mild genetic variant 1.3% and severe 1.2%. Cardiac malformation mild (61.4%) and severe (38.5%). Diaphragmatic defect size A and B (66.6%), C and D (22.8%). Caesarean section delivery is higher (61.4%) The most common long-term complications were thoracic deformity, intestinal obstruction and GERD. Surgical approach through abdomen (78.9%) is higher than other surgical approach. Outcome of the congenital diaphragmatic hernia of type A (38.59%)is higher among other types. Newborns with isolated CDH had a better prognosis compared to those with associated anomalies. Early surgical intervention within the first 48 hours of life was associated with improved survival rates.
Conclusion: The surgical management of CDH in newborns can lead to favorable outcomes, particularly when performed early and supported by comprehensive preoperative and postoperative care. Despite the challenges associated with CDH, prompt surgical intervention and meticulous postoperative management significantly contribute to improving survival rates and reducing complications. Further studies are needed to optimize treatment protocols and improve long-term outcomes for these patient
Unusual Cause of Congestive Heart Failure with Severe Mitral Regurgitation
Full text linkSub mitral aneurysm is a rare cardiac anomaly with varied clinical manifestations, usually due to congenital defect adjacent to posterior leaflet of mitral valve. We report 50-year-old male patient with submitral aneurysm who presented with features suggestive of congestive heart failure and severe mitral regurgitation. Echo cardiography and cardiac MRI aid in precise non-invasive diagnosis
Incidence and Risk Factors for Pneumonia and Diarrhea in Children under 5 in a Secondary Care Hospital
Full text linkBackground: Pneumonia and diarrhoea are two of the leading causes of morbidity and mortality, particularly in children under five years of age, especially in low- and middle-income countries. Both conditions are preventable and treatable, yet they remain significant health issues globally.
Objectives: The aim of the study was to evaluate the incidence and risk factors for pneumonia and diarrhea in children under 5 in a secondary care hospital.
Methods: This cross-sectional study was carried out in the Upazila health complex Matlab Uttar, Chandpur, Bangladesh, during January 2023 to December 2023. A total of 150 patients were participated in the study. Among them 60 were pneumonia patients (Group-A) and 90 were patients with diarrhea (Group-B). Statistical analyses of the results were be obtained by using window-based Microsoft Excel and Statistical Packages for Social Sciences (SPSS-24).
Results: The age distribution of the study population revealed that (53.33%) of patients in group A were between the ages of one month to one year, while (53.33%) in group B. In addition, 6.66% of the patients in group A were between the ages of 3 and 4 years old, while 10% were in group B. In group A, the bulk of the patients were male (63.33%), while group B had 51 (56.66%). There was no statistically significant difference (p>0.05) between the groups.
Conclusion: The need for targeted interventions to improve vaccination coverage, nutritional support, and sanitation practices to reduce the burden of pneumonia and diarrhoea in young children. Strengthening primary healthcare systems to provide early detection and management of these conditions is also essential in mitigating their impact
The Prevalence, Diagnosis, and Management of Voice Disorders in a Single Center Study
Full text linkBackground: Vocal disorders are challenging medical conditions to research nationally. Vocal disorders are a diverse collection of complaints based on symptoms, unlike other system-based illnesses that have well-defined pathologic, laboratory, or objective diagnostic criteria. No specialized national database or agency is in place to gather information on patients with voice problems. Large-scale epidemiologic studies that examine the prevalence, contributing causes, and available treatments for voice disorders are therefore uncommon. Objectives: This study was done to evaluate the prevalence, diagnosis, and management of voice disorders in a single center study. Methods: The cross-sectional study was conducted in the Department of ENT, Prime Medical College Rangpur from June 2021 to May 2022. A total of 60 subjects of both sexes were included in the study. Data were collected by face-to-face interview and analyzed by appropriate computer based programmed software Statistical Package for the Social Sciences (SPSS), version 22. Results: In this study, most of the patient 16 (26.6%) lies between 41 years to 50 years and about 38 (63.30%) patients were female and 22 (36.70%) patients were male. About 19 (31.7%) patients had acute condition and 24 (40.0%) had chronic condition. Most of the patients 73.3% had asthma, about 70% patients had respiratory allergy. About 38 (63.3%) had smoking habit and 22 (36.7%) patients were non-smoker. Most of the patients 37 (78.3%) had no family history of voice disorder and 13 (21.6%) had the family history. Conclusion: According to the current study, a significant proportion of VC patients\u27 diagnostic and treatment programs nationwide are in accordance with established guidelines. To improve care for patients with vocal issues, doctors of various specialties should be aware of these recommendations
A study of hematological profile and outcome in neonates born to mothers with pre-eclampsia and eclampsia in a rural tertiary care hospital in western Maharashtra
Full text linkAims and objectives: To study the hematological profile and outcome of neonates born to preeclampsia and eclampsia mothers in rural tertiary care hospital.
Materials and methods: This was a hospital based descriptive type of cross-sectional study in Dr.Vitthalrao Vikhe Patil Pravara Rural Hospital, Loni. It was carried out over a period of 1 year that is from September 2022 to September 2023.All neonates born to preeclampsia and eclampsia mothers being admitted in Dr.B V P Pravara Rural Hospital were included in the study.
Babies born with Congenital malformation and those born to mothers with other problems like rhesus incompatibility, severe anemia, renal disease, heart disease, and connective tissue disease were excluded from the study.
Results: In the present study 65% of babies were preterm, 34% of babies were more than 37 weeks, 54.5% of babies were born via normal vaginal delivery 45.5% of babies were born via cesarean section,15 % of babies have thrombocytopenia, 6 % of were <1kg birth weight,14% were in 1-1.5 kg range,79 % were in >1.5 to 2.5 kg range.
Conclusion: Babies delivered to hypertensive mothers are more likely to experience a variety of difficulties, it is important to closely monitor these infants to reduce morbidity and promote better growth, development, and survival