Medico Research Chronicles
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Emergency application of Ultra-High-Diluted-Biomedicines as Vaccine-Nationalism-Equity-Passport preventing-coronavirus-2: Developed Medical Health Clinical Research Science Technology Communications!
Get PDFThe reinfection of pandemic coronavirus-2 has been increasing day to day due to the introduction of new mutant adaptive variants, and so it has been needed urgently to protect the public health measures and individual preventive precautions must be sustained where long COVID-19 is recirculating- and causing the ‘Post-acute COVID-19 syndromes’. Initially, it has been observed that ginger is very much effective against the coronavirus-patients in the Municipality of Burdwan, West Bengal, India. But it is not always cost-effective and available enough for all. To overcome this, it has been urgently suggested to apply the different ultra-high-diluted potential-edible-medicines prepared from the rhizome, Zingiber officinale which will be cost-effective, eco-friendly, easily available, easily applicable, easily preparable, and side-effects-free any kinds of toxic free substances, against the pandemic coronavirus-2 as a policy-initiative-‘Vaccine-Nationalism-Equity-Passport’. And it is developed the “Medical-and-Clinical-Research or Medico Research Chronicles, Science, Technology, and Communication Informing the Easily Equitable, Marketable and Supply-able, etc.†which enriches the highest quality scientific information on all aspects of pharmacology and devoted to qualitative researches and up-to-date ongoing trends in the related field of medical and clinical research, which will enrich the scholars, academicians, and students every day across the world also in the new normal situation
Iron with folic acid supplemenation and birth weight in Ethiopia: Systemic review and meta-analysis
Get PDFObjective: The aim of this systemic review and meta-analysis was to examine the relationship between iron with folic acid supplementation and low birth weight in Ethiopia Previous studies on iron with folic acid supplementation and low birth weight indicated different findings. We include 24 studies in different regions of Ethiopia. We have done this study focusing on iron with folic acid supplementation.
Materials and Methods The databases searched were PUBMED and Advanced Google Scholar. on reference manager software reporting iron with folic acid supplementation and low birth weight. Three researchers have carried out the data extraction and assessed independently the articles for inclusion in the review using the risk-of-bias tool guided by the PRISMA checklist.
Results: Twenty-four observational studies involving 10989 participants, 2348 newborns have low birth weight were included. The combined effect size (OR) for low birth weight r comparing women who have an iron with folic acid supplementation versus women who did not have an iron with folic acid supplementation was 0.37 (95%CI 0.25 to 0.55), p<0.00001, I2 = 91 %). There was significant heterogeneity. No publication bias was observed, women reported iron with folic acid supplementation during current pregnancy in all studies, the proportion of low birth weight among women who reported iron with folic acid supplementation during the current pregnancy was 1392 (17.85%).
Conclusions: Women who take iron with folic acid supplementation during pregnancy have a 67% decreased in delivering low birth weight newborns in Ethiopia
Postoperative complications between ‘Total Intravenous Anesthesia with Propofol’ and ‘Sevoflurane Inhalation Anesthesiaâ€
Get PDFPropofol that\u27s generally used in total intravenous anesthesia (TIVA) has anti-oxidant and seditious inhibition parcels. It’s known that TIVA can drop postoperative nausea and vomiting (PONV) with little goods on pulmonary functions. Sevoflurane is a sweet-smelling, noninflammable, largely fluorinated methyl isopropyl ether used as an inhalational anesthetic for induction and conservation of general anesthesia. We\u27ve veritably many relative data regarding these two anesthetic agents. The aim of this study was to compare ‘total intravenous anesthesia with propofol’ and ‘sevoflurane inhalation anesthesia on postoperative complications. This retrospective study was conducted in Chattogram Maa-O-Shishu Hospital Medical College and different clinics, Chattogram, Bangladesh during the period from June 2019 to July 2020. In total 93 patients who had ENT surgeries previously were finalized as the total study population. Total patients were divided into 2 groups. In Group I there was 43 patients to whom total intravenous anesthesia with propofol (TIVA) had been used and in Group II there were 50 patients to whom sevoflurane inhalation anesthesia (SIA) had been used. Postoperative complications and recovery period were determined as tachycardia, bradycardia, hypertension, hypotension, recovery time, additional analgesia, and nausea-vomiting. For the patients who had surgeries under TIVA, the additional analgesia and nausea-vomiting incidences were found as 23.26% and 20.0% respectively and the recovery period was 12 minutes. On the other hand, for the patients who had surgeries under SIA, the additional analgesia and nausea-vomiting incidences were found as 20.0% and 34.0% respectively and the recovery period was 8 minutes. According to the analysis of complications regarding two different procedures, we found near about the similar performance. Although there was a difference between the lengths of recovery time that doesn’t a big issue to differ among the procedures. As it was a single-centered study with some unavoidable limitations, to get more specific information we would like to recommend conducting more studies in several places
Study of intraoperative challenges and early surgical outcome of phacoemulsification through temporal incision in patients with senile cataract at rural tertiary care hospital.
Get PDFIntroduction: Temporal phacoemulsification (Phaco) gives a better surgical outcome in senile cataracts as it nullifies, “against the rule astigmatism†which is common in elderly patients. It is a well-established, effective and safe technique. We conducted this study to verify the surgical outcome of temporal phacoemulsification at a rural tertiary care hospital (RTCH).
Aims and Objectives: To study the intra operative and early post-operative complications, post-operative UCVA (Uncorrected Visual Acuity) and BCVA (Best Corrected Visual Acuity) in patients with senile cataract who underwent temporal phacoemulsification.Materials and Methods: In this prospective, hospital-based observational study, we studied intraoperative and postoperative data of 42 patients, above 50 years of age, who underwent temporal phacoemulsification for senile cataracts from August 2019 to May 2020 after obtaining institutional ethical committee approval and written informed consent from all patients. All patients underwent minimum 6 weeks of postoperative follow-up.
Results: Out of 42 patients, 57.14% were females and the most common age group was 61-70 years. Intraoperative bleeding was seen in 19.04% of patients and the post-operative mild corneal stromal haze and mild uveitis were seen in 4.76% and 7.14% of patients on a postoperative day 1(POD 1) respectively. Reduction in preoperative “against the rule astigmatism†was seen in 68% of patients. All patients had a UCVA of >6/12 and a BCVA of 6/6 at the last follow-up.
Conclusion: Temporal phacoemulsification gives a good UCVA and faster visual rehabilitation in patients with senile cataracts
Microorganisms detected on gloves contaminated by first year MBBS students during dissection of formalin-fixed cadavers
Get PDFIntroduction: The study is done with the purpose to detect if any microorganisms are detected on the dissection of formalin-fixed cadavers which can be a potential of infection for students.
Material and Method: Students were made to do a dissection of routinely preserved cadavers using gloves. Samples from the contaminated gloves were collected and sent for culture and sensitivity.
Observation and results: A variety of microorganisms were cultured from the given samples.
Conclusion: The results indicate that cadavers fixed with formalin are a potential source of infection for students as well as faculty. This study underscores protocols to decrease cross-contamination
Dissection hall experience of first year medical students
Get PDFDissection is a special curiosity for First Mbbs Students. It is remembered for life long by medical students. The experience of dissection cannot be forgotten for a lifetime. The first day of entering the dissection hall remains the best memory for medical students. First-Year Students are at crossroads. From a non-professional career, they enter into a professional career. This sudden change and transformation have many implications. They take time to adjust to new forms of education, responsibility, and changes. First professional Studies are demanding as well. There are many modalities of teaching in the Subject of Anatomy like Theory, Practicals of Histology. Dissection is an entity special to Anatomy and very different from other skills. There is a special and unique response to dissection by first-year medical students. It happens to be their first interaction with the human body in real-time. There is a range of feelings like excitement, fear, unpleasant feeling, fatigue associated with dissection. Dissection is the central pillar of anatomy. First-year medical students on their encounter with the cadaver for the first time experience a variety of reactions and mixed feelings. The present study was carried to assess the experience of first-year medical students towards the human cadaveric dissection and its physical and emotional aspect
Anthropometrical variations in cephalic index in Indian medical students and its relation with sex
Get PDFIntroduction: Cephalic index is useful anthropologically for deciding the race and sex of an individual as it is greatly affected by age, sex, geographical factors.
Material and methods: In the present study, 90 medical students were taken as subjects and head length, head breadth, and cephalic index were measured. Aim: To study anthropometrical variations in the cephalic index in Indian medical students and its relation with sex.
Results: Indian males had a mean cephalic index of 78.01 and they were mesocephalic and females had a mean cephalic index of 81.41and were brachycephalic.
Conclusion: The data is important in forensic medicine, anthropology, genetics, and the identification of individuals
Manufacture of fibroustructure facemask to protect against coronavirus using electrospinning
Get PDFIn order to live safely with an exacerbation of the Coronavirus, a face mask must be made with specifications that prevent infection or transmission among people; which is characterized by high efficiency and low cost, and renewable. Fiberstructure widely used in air filtration industry using electrospinning method, where its field is booming in an exceptionally impressive manner. Using a biopolymer as a olyhydroxyalkanoates (PHAs) to create a facemask will give excellent results because of the solidity and porosity of the polymer in addition to the non-stick feature. During this work, emphasis will be placed on the best method to manufacture the face mask in terms of the solidity and non-stick feature which gives a longer life for facemask. The facemask is quicker and more affordable than delivering a treatment or a counteractant, and furthermore gives the facemask better outcomes against the Coronavirus
Copper and copper containing pesticide as copper oxychloride toxicity and its adverse effects on animal and human health
Get PDFCopper is a trace element and has a vital role in homeostasis but it has cumulative effects and may be hazardous to the animal, human, and environment. Copper is a vital trace element to all living as it participates in various metabolic processes and is controlled via complicated homeostatic mechanisms, but excess copper has a deleterious effect in organisms as it stimulates free radical production in the living cell, lipid peroxidation, and disturbs the whole-body antioxidant capacity. Although its beneficial effect, it has a hazardous effect on health as it has genotoxic, developmental toxicity, and hepatic toxicity in experimental animal
To determinate the degree or severity of renal impairment according to HIE stages in PNA patients
Get PDFIntroduction: Perinatal asphyxia is a major cause of acute renal failure in neonates. So it is essential to evaluate the renal function at an early stage to stabilize fluid and electrolyte balance which is of great importance to infants with hypoxic-ischemic encephalopathy. Yet, it is not quite easy to evaluate neonatal renal function accurately. Objective: To Determinate the Degree or Severity of Renal Impairment According To HIE Stages in PNA Patients. Materials and Methods: This cross-sectional study was carried out in the department of neonatology, Chattagram Ma-O-Shishu hospital from January 2016 to June 2016. All Perinatal asphyxia patients admitted in the department of neonatology, Chattagram Maa-Shishu O General Hospital fulfilling the inclusion criteria were included in the study. As the study was done in a single center and due to time constrain 180 cases were enrolled in this study. After taking informed written consent from legal attended a total of 150 asphyxiated and 30 non-asphyxiated newborns were selected by purposive sampling. Results: During the study period, there were total 197 eligible infants. Among them 154 were case and 43 were control. Among the cases 2 infants left against medical advice (LAMA), 1 infant died, and 1 was excluded due to lack of parental consent. Among the control 13 were excluded due to lack of consent. Finally 150 asphyxiated newborn were selected as case and 30 normal infants were included as control in the study. In this study, stage I, 50(60.2%) baby has normal RFI and 33 (39.8%) babies has abnormally high RFI. For stage II, 23 (43.4%) baby has normal RFI and 30 (56.6%) baby has abnormally high RFI and for stage III, only 5 (35.7%) baby has normal RFI and 9 (64.3%) baby has abnormally high RFI. Their P-value is 0.070, which is statistically not significant. The study also shows Mean ± SD of RFI value in stage I is 2.76 ± 0.62, for Stage II is 3.17 ± 0.67, and for stage III, is 3.17 ± 0.28 and “p†value 0.001 which is statistically highly significant. Conclusion: In conclusion, AKI represents a significant problem among asphyxiated neonates. All of the hyperechogenic kidney patients were also hyperuricemic, which supports the possible association between both features. In addition, uric acid itself might be the causative factor for failure in addition to hypoxic and ischemic insult. We recommend kidney functions, and abdominal ultrasonography to be done routinely in asphyxiated neonates to evaluate the possibility of acute kidney injury in them. FENa and RFI are useful parameters for assessing renal function and urinary β2M is a good biomarker for diagnosis and prognosis of acute tubular injury in term babies with perinatal asphyxia