RODBUK Jagiellonian University in Kraków
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Experimental pharmacology of endothelium under flow conditions
The dataset includes data on the effect of shear stress generated by fluid flow on endothelial cells cultured in the laboratory
ToF-SIMS Negative-Ion Profiling of Hepatic Lipids and Amino Acids in Lean, Diabetic and Metformin-Treated Zucker Diabetic Fatty Rats
This dataset contains raw and processed Time-of-Flight Secondary Ion Mass Spectrometry (ToF-SIMS) data acquired from liver tissue sections of lean (LEAN), diabetic (P1), and metformin-treated (P2) Zucker diabetic fatty rats. Data were generated to characterise diabetes-induced metabolic alterations in hepatic lipid and amino-acid profiles and to assess the normalising effects of metformin.
The dataset includes raw ToF-SIMS spectral files in negative-ion mode, averaged group spectra, peak-intensity tables normalised to total ion counts (TIC), results of the one-way ANOVA with FDR correction, volcano-plot source files, hierarchical clustering matrices
Significance matters: fresh perspectives on effort dynamics in managing psychological discrepancies
In the original Cognitive Dissonance Theory, Festinger argued that the higher the personal importance of the conflicting elements in the system, the greater the magnitude of the dissonance in their relation. So, in other words, we may say that when elements are not important the dissonance should not occur. However, it is not the case, recent research has suggested, that simple cognitive inconsistency may also evoke the affective and motivational state of the dissonance (e.g., E. Harmon-Jones, Harmon-Jones, & Levy, 2015; Levy, Harmon-Jones, E. Harmon-Jones, 2018). We propose that personal importance does not influence the magnitude of the dissonance itself, but rather sets directly (not via the magnitude of the dissonance) the level of the motivation to dissonance reduction. We tested this assumption in one correlational and two experimental studies from witch data (total N= 846). The results were in line with our predictions, and thus we modestly propose how the classical theory can be remodeled to broaden its boundary conditions. Here we deposited for open use the data from the project
Comparative study of spheroids growth originating from pre incubation in multiwell plates and cell suspension
Purpose:
1.Comparision of growth between spheroids (cell line DU145) originating from two different methods of inoculation: preincubation in multiwell plate; cell suspension.
2.Production of cells and spheroids from cell lines: DU145 and LNCaP for PALS measurments.
3.Production of cells from cell line DU145 for (52)Mn experiment.
4.Production of cells (DU145) and spheroids (LNCaP) for (55)Co experiment.Dataset contains data from Celigo analysis of spheroids growth for the period of their subculture; pictures of cells for both cell lines (DU145; LNCaP); analysis of Celigo data; raports from conducted cell cultures
Polish adaptation and further psychometric evaluation of structure and test-retest reliability of Chronic Pain Values Inventory (CPVI)
The dataset is part of a larger project involving two studies. Study 1: this study was conducted online. The dataset contains information gathered from 418 participants suffering from chronic pain lasting more than 3 months and a physician's diagnosis of a medical condition associated with chronic pain. The dataset encompasses sociodemographic data, including age, gender, marital status, employment status, educational level, and place of residence. Additionally, it features data from a medical history survey, and the following standardized questionnaires: the Polish Version of the Chronic Pain Acceptance Questionnaire (CPAQ-8) (McCracken, Vowles & Eccleston, 2004) [items: 1-8],Pain Anxiety Symptoms Scale-20 (PASS-20) (McCracken & Dhingra, 2002) [items: 1-20], Chronic Pain Values Inventory (CPVI) (McCracken & Yang, 2006) [importance score items: 1-6; success score items:1-6], Depression Anxiety Stress Scales-21 (DASS-21) (Lovibond and Lovibond, 1995) [items: 1-21], Committed Action Questionnaire (CAQ-8) (McCracken et al., 2015) [items: 1-8]. Study 2: The dataset contains information gathered from 148 individuals. Participants with the presence of chronic pain lasting more than 3 months, and a physician's diagnosis of a medical condition associated with chronic pain were recruited from pain management facilities in Poland. The dataset includes sociodemographic data such as: age, gender, marital status, employment status, education level and place of residence. Additionally, it features data from a medical history survey, and the Polish Version of the Chronic Pain Acceptance Questionnaire-Revised (CPAQ-8) [items: 1-8], Pain Anxiety Symptoms Scale-20 (PASS-20) (McCracken & Dhingra, 2002) [items: 1-20], Chronic Pain Values Inventory (CPVI) (McCracken & Yang, 2006) [importance score items: 1-6; success score items:1-6]
Soil erosion - Rainfall thresholds
Rainfall thresholds for soil erosion by water were determined based on rainfall data for a 23-year period (1987–2009) and long-term field data on rain splash, slope wash, and linear erosion in an agricultural foothill catchment in southern Poland. Stationary measurement of soil erosion by water was conducted on runoff plots in Dworski Potok catchment located in the village of Łazy, in the lowest marginal zone of the Carpathian Foothills (Brzesko Foreland). The catchment covers the area of 0.29 km2, the ranges of altitude being 227-275 m a.s.l. In determining threshold values, the definition of erosive rain was adopted from the USLE model, and rainfall erosivity [EI30] and maximum 30-minute rainfall intensity [I30] were used as the main parameters to assess rainfall’s ability to trigger erosion
MCPIP3 orchestrates the balance of epidermal proliferation and differentiation - raw research data
Dataset of raw data related to the publication doi: 10.1186/s12964-025-02184-1
The prevalence of genetic variants of the Mas-related G-protein-coupled receptor X2 in patients does not explain perioperative hypersensitivity reactions to neuromuscular blocking agents
Raw molecular dynamics data used to generate the results presented in the article. Demographic data of the study groups and continuous and ordinal variables used to classify the subjects into subgroups for comparisons
Multifunctional Hydrogel Flakes: An Innovative Approach to Localized Delivery of Temozolomide
Data generated during studies on the multifunctional hydrogel-based implantable flakes for the local delivery of temozolomide are provided. The raw experimental dataset consists of the physicochemical evaluation of developed hydrogel-based systems (the degradation, swelling and amine groups determinations experiments). In addition, data from model drug release experiments performed under physiological conditions are presented. Moreover the selected dataset regarding the biological evaluation in vitro was also provided. The developed materials were analyzed for their hemostatic properties. Citrated whole blood from a healthy donor was obtained from the Regional Center for Blood Donation and Treatment in Kraków. Before the experiment, the blood and the test materials (prepared in specified dimensions) were equilibrated to 37 °C. To neutralize the anticoagulant effect of sodium citrate, 25 mM CaCl2 was added to the blood. The amount of hemoglobin released from lysed erythrocytes was quantified spectrophotometrically at 540 nm. The percentage of non-clotted RBC (red blood cells) was measured based on absorbance, with the total amount of unclotted erythrocytes assumed to be 100%. Absorbance was measured using a Synergy H1 Hybrid microplate reader with Gen5 software, version 2.00.18 (BioTek Instruments). The data was exported to an excel file
Influence of the polycation structure on the physicochemical and biological properties of polyplex of heparin and aptamers systems - replication data
Raw data together with description measured for publication: "Influence of the polycation structure on the physicochemical and biological properties of polyplex of heparin and aptamers systems" Colloids and Surfaces B: BiointerfacesVolume 258, February 2026, 115269 https://doi.org/10.1016/j.colsurfb.2025.11526