Van Yüzüncü Yıl University Research Information System
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LC-MS/MS-based phenolic profiling and IRAP-PCR analysis reveal biochemical and genomic responses of flax (Linum usitatissimum L.) to salt stress
No full textBackground: Salinity is a major abiotic stress factor that affects plant growth, secondary metabolism, and genomic stability. Phenolic compounds and antioxidant capacity are key biochemical indicators of plant stress responses, while retrotransposon activity reflects molecular-level genomic plasticity. This study investigated the physiological and molecular responses of Linum usitatissimum L. (flax) to different salt concentrations, aiming to better understand the mechanisms underlying salinity tolerance. Methods and results: Flax plantlets were grown in vitro on Murashige and Skoog (MS) medium supplemented with 15, 30, or 60 mM NaCl for 15 days. Total phenolic content (TPC) was quantified using the Folin–Ciocalteu method, while antioxidant activity was assessed via DPPH and ABTS radical scavenging assays. LC-MS/MS was employed to identify and quantify individual phenolic compounds, and IRAP-PCR was used to evaluate retrotransposon mobility. Salinity resulted in a significant reduction in biochemical parameters. TPC decreased from 1.13 µg GAE/100 µg extract in the control to 0.85, 1.06, and 0.69 µg GAE under 15, 30, and 60 mM NaCl, respectively. Antioxidant activity showed a similar decline: DPPH inhibition dropped from 25% (control) to approximately 12% under 60 mM stress, while ABTS inhibition decreased from over 90% to approximately 72% at 0.03 mg/mL. LC-MS/MS profiling revealed salt-sensitive reductions in chlorogenic acid, caffeic acid, trans-ferulic acid, and naringenin, with chlorogenic acid particularly diminished at 60 mM NaCl. At the molecular level, IRAP-PCR yielded high polymorphism rates, ranging from 50% to 100% (primer 1845), 60% to 100% (1846), 54% to 100% (1875), and 36% to 100% (1899), indicating enhanced retrotransposon activity under increasing salinity. Conclusion: Overall, rising salt concentrations reduced phenolic accumulation and antioxidant potential while increasing retrotransposon-mediated genomic variability in flax. These results suggest that both biochemical markers (phenolics, antioxidant activity) and molecular indicators (IRAP polymorphism) are valuable tools for assessing salinity stress responses and can support the development of salt-tolerant cultivars in flax breeding programs
Hydrothermal liquefaction of sinapis arvensis biomass using TiO₂-supported metal catalysts: A study on bio-oil yield and composition
No full textThe development of catalytic systems for hydrothermal liquefaction (HTL) is crucial for transforming lignocellulosic biomass into biofuels with high energy density. This research investigates the HTL process of Sinapis arvensis biomass using TiO₂-supported catalysts, specifically Fe, Al, and Fe–Al, at temperatures from 275–325 °C. The catalysts were synthesized through incipient wetness impregnation and characterized using techniques like X-ray diffraction (XRD), X-ray photoelectron spectroscopy (XPS), X-ray fluorescence (XRF), scanning electron microscopy with energy dispersive X-ray spectroscopy (SEM-EDX), and inductively coupled plasma optical emission spectrometry (ICP-OES) to evaluate element distribution and surface chemistry. Findings show that the Al/TiO₂ catalyst boosted lighter bio-oil production via acid-catalyzed dehydration and decarboxylation, while the Fe/TiO₂ catalyst favored heavier oils through redox-assisted depolymerization. The Fe–Al/TiO₂ bifunctional catalyst exhibited superior biomass conversion, yielding more aliphatic hydrocarbons. Gas chromatography-mass spectrometry (GC-MS) revealed how catalysts influenced product distributions, increasing monoaromatic and aliphatic compounds and reducing oxygenated entities. Elemental analysis confirmed higher carbon content, lower oxygen levels, and improved higher heating values (HHVs) in catalyzed bio-oils, indicating enhanced fuel quality
Synergistic Pd and Bi decoration on g-C3N4: Toward high-performance glycerol fuel cell anode catalyst
No full textGlycerol electrooxidation (GEOR) in an alkaline medium was assessed using graphitic carbon nitride (g-C3N4)-supported PdBi bimetallic catalysts with different atomic ratios that were created using a NaBH4 reduction technique. The catalysts were comprehensively characterized by Inductively coupled plasma mass spectrometry (ICP-MS), X-ray Diffraction (XRD), X-ray Photoelectron Spectroscopy (XPS), N2 adsorption–desorption, Scanning Electron Microscopy–Energy Dispersive X-ray Spectroscopy (SEM-EDX), and elemental mapping, and electrochemical techniques namely cyclic voltammetry (CV), chronoamperometry (CA), linear sweep voltammetry (LSV), and electrochemical impedance spectroscopy (EIS). Pd70Bi30/g-C3N4 had the best electrocatalytic performance among the synthesized catalysts, with the lowest onset potential (–0.31 V), the lowest charge transfer resistance, and the highest specific/mass activity (9.60 mA/cm2 and 180.8 mA/mgPd). Pd and Bi's synergistic interaction, the optimal d-band center position, and the efficient dispersion of nanoparticles on g-C3N4 were all credited with the increased activity. These findings show how atomic ratio tweaking and support material selection can be used to create high-performance anode catalysts for direct glycerol fuel cells (DGFCs)
Trace element and mineral levels in tissues of selected Capoeta fish species collected from Botan River, Siirt
No full textDesign and characterization of ilmenite-enriched borate glasses for advanced gamma and fast neutron shielding applications
No full textIn this work, a novel series of lithium tetraborate (Li2B4O7) glasses doped with ilmenite (FeTiO3) at 0, 5, 10, 15, and 20 wt% were synthesized using the melt-quenching technique. The samples were coded as I0 (undoped), I5, I10, I15, and I20 according to their ilmenite content. X-ray diffraction (XRD) confirmed their amorphous structure, while density increased systematically from 2.263 g/cm3 (undoped) to 2.418 g/cm3 for the 20 wt% ilmenite glass (I20). Gamma-ray attenuation was studied using a 3 Ci 133Ba source and Ultra Ge detector over 81–383 keV. At 81 keV, the linear attenuation coefficient rose from 0.382 cm−1 (I0) to 0.494 cm−1 (I20), representing a ∼29 % improvement. Similarly, the half-value layer decreased from 3.135 cm to 2.783 cm at 383 keV, while the effective atomic number increased from 7.4 to 8.2 at low energies. Buildup factors (EABF and EBF) also showed up to 30 % lower values in I20 at 15 mean free paths, indicating reduced secondary photon generation. Neutron attenuation tests with a 10 mCi Am–Be source and BF3 detector revealed a slight decrease in ΣR (0.1096–0.1057 cm−1), but the absorbed dose rate improved from 26.99 % to 29.21 % upon ilmenite addition. Overall, the incorporation of ilmenite enhanced both photon and neutron shielding without compromising structural integrity, confirming that these glasses are promising materials for advanced radiation shielding in nuclear, medical, and aerospace applications
Histological and immunohistochemical responses of the kidney in Van fish (Alburnus tarichi) during upstream migration
No full textThe relationship between PDE4 and AQP5 in lung tissue under inflammatory conditions: An experimental study
No full textObjective: This study aimed to examine the relationship between Phosphodiesterase 4 (PDE4) and Aquaporin-5 (AQP5) under Lipopolysaccharide (LPS) induced-inflammatory condition. Methods: Inflammatory Acute lung injury (ALI) was induced by intratracheal LPS (5 mg/kg) administration. Rolipram (intraperitoneal) was used as PDE4 inhibiting agent at three different doses (1, 3 and 5 mg/kg) in rat groups. 24 h after LPS administration lung tissues obtained and following analyses performed. AQP5, Phosphodiesterase 4D (PDE4D), Cyclic adenosine monophosphate (cAMP) levels were evaluated for determination of the relationship between these parameters. Also Interleukin-6 (IL-6), Tumor necrosis factor-α (TNF-α), Nuclear factor kappa B (NF-κB), Mitogen-activated protein kinase (MAPK) levels were evaluated as ALI markers. Results: LPS-induced ALI resulted in increased PDE4 enzyme and inflammatory marker levels (IL-6, TNF-α, NF-κB and MAPK) and decreased AQP5 and cAMP levels. Inhibition of PDE4 enzyme to increase cAMP levels by Rolipram resulted in increased AQP5 expression and decreased inflammatory condition and in lung tissues. These results were supported by histopathological and immunhistochemical results. Conclusion: The fact that this study observed a decreases PDE4 expression and increases in AQP5 expression upon Rolipram administration might indicate a close relationship of these two parameters in inflammatory lung disease
Factors Affecting Agricultural Credit Usage Among Peanut Farmers in Türkiye
No full textAgricultural credit is a critical financial tool for farmers to sustain and develop their agricultural activities, especially inrural areas where capital shortages are common. The aim of this study was to identify the factors influencing the use ofagricultural credit by peanut farmers in Silopi District of ¸Sırnak Province and to determine whether there are significantdifferences in sociodemographic and business characteristics between farmers who use agricultural credit and those who donot. The main material of the study comprised survey data collected from 64 farmers selected using proportional sampling.Descriptive statistics and binary logit models were used for data analysis. Binary logit results showed that overall model fitwas good, with most socioeconomic factors being significant. The following socioeconomic factors positively influencedagricultural credit use: schooling years, farming experience, frequency of visits to provincial and district directorates ofagriculture, having a high school or higher level of education, being married, benefiting from agricultural subsidies, andhaving agricultural insurance. On the other hand, having off-farm income, following agricultural innovations, and thevolume of peanut production negatively influenced the use of agricultural credit. Based on the results, it is recommended toenhance agricultural extension services, raise awareness of credit options, and develop support programs targeting farmerswith limited access to institutions. Simplifying credit application processes and offering customized financial productscould also increase credit use among small-scale peanut farmers</p
Effects of mandala art therapy (coloring) on nausea, vomiting, pain and anxiety in children and youth receiving outpatient chemotherapy
No full textPurpose This study was designed as a randomized controlled trial (RCT) with a pretest-posttest design to investigate the effects of mandala art therapy on nausea, vomiting, pain, and anxiety in children and youth undergoing outpatient chemotherapy. Method This study was conducted between April 15 and October 15, 2024, at the Pediatric Outpatient Chemotherapy Unit of a hospital. The study included children and youth aged 9-17 diagnosed with hematological malignancies, solid tumors, or hematological disorders accompanied by oncological conditions. The experimental group received mandala art therapy, while the control group continued with the standard protocol. The study utilized the Personal Information Form, Nausea-Vomiting Thermometer, Wong-Baker Faces Pain Rating Scale, and the State-Trait Anxiety Inventory for Children (STAIC). Data were summarized using descriptive statistics and normality was assessed using the Shapiro-Wilk test. For data that did not follow a normal distribution, the Mann-Whitney U and Wilcoxon Signed Rank tests were applied. Results Significant differences were observed between the experimental and control groups in the of nausea, vomiting, pain, and anxiety levels post-treatment. In the experimental group, a significant reduction was observed in the nausea-vomiting and pain scores before and after the treatment ( p 0.05). Additionally, a significant decrease in the anxiety scores was found in the experimental group after treatment, whereas no significant difference was observed in the control group (p > 0.05). Conclusions Mandala art therapy effectively reduces nausea, vomiting, pain, and anxiety in children undergoing outpatient chemotherapy and it appears to be a feasible and effective psychosocial intervention that could be integrated into routine supportive care in pediatric oncology. Future studies should investigate its long-term effects and in different pediatric age groups
AVÜLSİYON SONRASI ESTETİK REHABİLİTASYONDA GROPER APAREYİNİN KULLANIMI: OLGU SUNUMU
No full textAmaç: Bu olgu sunumu, avülsiyon–sublüksasyonyaralanmasının konservatif olarak yönetimini veanterior bölgede oluşan estetik–fonetik kaybın Groperapareyi ile rehabilitasyonunu ortaya koymayıamaçlamaktadır.Olgu içeriği özeti: Sekiz yaşındaki erkek hasta,bisiklet kazasından dört gün sonra üst anteriorbölgede, dişlerinde hareketlilik şikâyetiyle kliniğebaşvurdu. Anamnezde 11 numaralı dişin olay yerindeavülse olduğu, 21 numaralı dişte ise travma sonrasımobilite bulunduğu öğrenildi. Klinik muayenede 21numaralı dişte sublüksasyon ile uyumlu, derece 2mobilite saptandı. Radyografik değerlendirmede ek birpatoloji izlenmedi. Travmadan etkilenen dişlerinstabilizasyonu amacıyla dört hafta süreyle semi-rijidsplint uygulandı ve travma sonrası bakım önerileriverildi. Dört haftalık splintleme süresini takiben, 21numaralı dişin stabil hale geldiği ve bölgenin uyguniyileşme gösterdiği belirlendi. Avülse olan 11 numaralıdişin yerinin estetik ve fonetik açıdan rehabilitasyonuiçin Groper apareyi tercih edildi. Takiplerde apareyinretansiyon, oklüzyon ve fonetik uyum açısındanyeterli olduğu ve komplikasyon gelişmediği görüldü.Olgu, anterior dental travma sonrası konservatifstabilizasyonu takiben Groper apareyinin estetik vefonetik açıdan başarılı bir rehabilitasyon sağladığınıgöstermektedir.Anahtar kelimeler: Avülsiyon, dental travma,sublüksasyon, yer tutucuEtik beyan: Bu olgu sunumu için hastanınebeveyninden yazılı bilgilendirilmiş onam alınmıştır.Aim: This case report aims to present theconservative management of an avulsion–subluxationinjury and the rehabilitation of the resulting estheticand phonetic loss in the anterior region using aGroper appliance.Summary of the case content: An eight-year-oldmale patient presented to the clinic with a complaintof mobility in the upper anterior teeth four days aftera bicycle accident. Medical history revealed that oneof the maxillary central incisors had been avulsed atthe accident site, and the contralateral central incisorexhibited mobility following the trauma. Clinicalexamination showed grade 2 mobility in the affected<p class="p1" style="margin