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Investigating the Nature of Interaction in Early Childhood Pedagogical Documentation Contexts
No full textAn increasing amount of research has focused on the characteristics of interactions in early childhood settings. Nevertheless, there is a scarcity of studies that have thoroughly examined the specific contexts and methods employed to enhance interaction. This article explores case study research findings that examine the interaction among pedagogical documentation contexts. The participants of the study were three early childhood teachers implementing pedagogical documentation working in an independent preschool institution. Data include interviews and longitudinal observations collected over four months. The findings demonstrated clear evidence of supportive and responsive interactions by early childhood teachers. The findings from this study are underpinned by the themes of: asking questions, providing feedback, enhancing child autonomy, organizing collaborative learning environments, and teacher responsiveness. This study points to the importance of pedagogical documentation operating as a tool to enhance classroom interaction in early years. It also calls for more research on early childhood contexts in supporting interaction and the need to further understand the relationship between teacher practices and classroom interaction
Cystic interstitial lung disease in adults starting in early childhood: A novel biallelic CCR2 variant hampering monocyte recruitment to the lung
No full textAre there any differences between adult-onset cerebellitis and childhood cerebellitis?
No full textAcute cerebellitis (AC), a rare inflammatory disorder of the cerebellum, is primarily associated with infectious, post-infectious, and autoimmune mechanisms. It predominantly affects children and typically follows a benign and self-limited course. This study, the largest case series to date focusing exclusively on adult-onset AC, reveals distinct clinical, laboratory, and imaging characteristics compared to the pediatric AC literature. We included 16 patients (mean age of 39.5 years) who met the clinico-radiological features of AC. The causes of AC in this study were varied, encompassing paraneoplastic, post-infectious, infectious, anti-GAD-related, and hemophagocytic lymphohistiocytosis etiologies. The most common symptoms were altered consciousness, dysarthria, ataxia, vomiting, fever, headache and seizures. All cases showed bilateral cerebellar involvement on MRI, predominantly affecting the cerebellar cortex. Hemorrhage within cerebellar lesions was observed in three patients. Outcomes were often severe, with 56% of patients experiencing severe sequelae and 31% mortality. This study highlights the distinct characteristics and potential for severe outcomes in adult AC, emphasizing the need for a comprehensive diagnostic approach
Time-Dependent Rheological Behavior of Surface-Coated Calcite Powder: Implications for Industrial Applications
No full textIn this study, the effects of stearic acid coating concentration (0.85%, 1%, and 1.15% wt.) and storage duration (up to 30 days) on the flow properties of surface-modified micronized calcite powder were investigated to evaluate their implications for critical industrial processes including transportation, feeding, dispersion, and production capacity. The results demonstrated that both stearic acid concentration and storage duration significantly influenced the rheological properties of the coated calcite powders, suggesting that the calcite surfaces had dynamic characteristics. The Conditioned Bulk Density (CBD) values increased significantly from day 1 to day 30, indicating efficient packing of the powders. Although stearic acid-coated calcite powders initially demonstrated enhanced flowability (SE: 5.1 -> 3.7 mJ/g; BFE: 77 -> 59.3 mJ) within the first 8 days, a subsequent increase (SE: 4.6 mJ/g; BFE: 74.3 mJ) by day 30 indicated a time-dependent surface reorganization of the coated particles. The reduction in the Flow Rate Index (FRI) values after a 30-day period indicated a decrease in cohesiveness. The stability index (SI) values initially indicated instability but improved after 30 days. These findings highlight the importance of considering the coating amount and time-dependent behavior when designing experiments, formulating products, and establishing quality control procedures involving calcite fillers
Lymphocyte activation gene-3 (LAG-3) and cluster of differentiation-155 (CD-155) expression by immunohistochemistry do not predict response and survival in non-small lung cancer (NSCLC) patients treated with second-line nivolumab treatment
No full textFrom Perception to Sustainability: Validating a Tool to Assess Students' Awareness of the Ecological, Utilitarian, and Cultural Roles of Plants
No full textThis study presents the development of the Plant Perception Scale (PPS), a multidimensional tool designed to assess high school students' awareness of the ecological, utilitarian, and cultural significance of plants. Positioned within the broader goal of Education for Sustainable Development (ESD), the scale aims to identify perception gaps that may hinder students' engagement with biodiversity and sustainability. Following a rigorous development process-including item generation, expert review, pilot testing, and psychometric validation-the final 21-item scale revealed a three-factor structure: Ecological Awareness and Sustainability Perception (12 items), Utility-Oriented Plant Perception (5 items), and Cultural and Aesthetic Perception (4 items). Exploratory Factor Analysis confirmed data suitability (KMO = 0.920; Bartlett's chi(2)(210) = 2245.215, p < 0.001). Confirmatory Factor Analysis supported the structure with strong fit indices (chi(2)/df = 2.204; CFI = 0.949; RMSEA = 0.055). Internal consistency was high (Cronbach's alpha = 0.88 for the total scale; factor alpha values ranged from 0.823 to 0.939). The PPS contributes to sustainable education by offering a reliable framework to evaluate plant-related awareness among adolescents and can serve as a diagnostic and pedagogical tool to guide curriculum development and educational interventions in support of the SDGs
Female lineages and changing kinship patterns in Neolithic Çatalhöyük
No full textCombining 131 paleogenomes with bioarchaeological and archaeological data, we studied social organization and gendered practices in & Ccedil;atalh & ouml;y & uuml;k East Mound (7100 to 5950 BCE), a major Neolithic settlement in Central Anatolia. In early & Ccedil;atalh & ouml;y & uuml;k, burials in the same building were frequently close genetic relatives, suggesting that houses were used by biological family members. In later periods, however, individuals buried in the same building were often genetically unrelated, despite sharing similar diets. We found no indication of sex-biased mobility into & Ccedil;atalh & ouml;y & uuml;k. Meanwhile, in all periods, within-building genetic connections were predominantly maternal rather than paternal. Burials of female subadults also received a higher frequency of gifts than male subadults. Our results reveal how kinship practices changed while specific practices prioritizing female lines persisted for 1000 years at Neolithic & Ccedil;atalh & ouml;y & uuml;k