IRIS Università degli Studi dell'Aquila
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‘Monte Parnaso. Mascarata da Cavalieri Napoletani’ (1630). Feste, balli e cerimoniali a Napoli per l’Infanta di Spagna
No full textLa mascherata Monte Parnaso, con versi di Giovan Battista Basile e musiche di Giacinto Lambardi, è segmento di una lunga festa organizzata il 17 ottobre 1630 a Napoli per onorare il soggiorno in città di Maria Anna d’Austria, Infanta di Spagna. In questa ‘forma intermedia’ (Warburg), la qualità del testo letterario, la potenza evocatrice della musica e le componenti architettoniche della scenografia mirano a conquistare lo spettatore, a consolidare l’autorità del sovrano e a celebrare l’intellighenzia napoletana coinvolta nell’organizzazione e messa in scena dell’evento
The impact of urban models on social support – Between spatial justice and sustainable development
Get PDFTerritorial disparities condition the well-being of communities, affecting access to essentialservices and the possibility of building and maintaining meaningful social networks. Differ-ences in the distribution of infrastructure, the quality of urban spaces, and opportunities forsocial interaction can amplify isolation situations, especially impacting the most vulnerablesegments of the population. This study, conducted in four municipalities in the Province ofL’Aquila, analyses the phenomenon according to two dimensions: the spatial one, linked tourban planning and the location of primary services, and the social one, related to perceivedsocial support. The results underline the importance of inclusive planning that promotes spa-tial justice and equitable access to services, in line with the Sustainable Development Goal
Living Beyond the Edge: Impacts of Climate Change on Rock Lizards at the Niche Margin
Get PDFEctotherms are particularly threatened by climate change because they are strictly reliant on environmental conditions for homeostasis. Increasing environmental temperatures may approach the species' critical thermal maximum, with deleterious effects on individual thermoregulation capacities. This study tests the hypothesis developed in a recent work that under ongoing global warming populations living in sites at the warm edge of the species' thermal niche will suffer a disruption of the thermoregulation process, with detrimental effects at the individual and population level. We collected individual measurements and temperature data for Mediterranean endemic rock lizards, across the entire distribution range of the species and during two different sampling periods ~20 years apart to compare thermoregulation coefficient (C), body condition index (BCI) and population size under different climatic conditions. We found that C and BCI vary across space and time following a linear pattern along the thermal niche gradient (Niche Margin Effect, NME) until a threshold temperature, beyond which the NME is disrupted. This threshold temperature indicates the warm edge of the species' thermal niche. A slightly higher temperature marks the threshold at which we observed significant population declines over the 20-year study period in the warmest sites. This suggests a lagged response of population trends to climate warming. This study suggests a mechanism of disruption of homeostatic processes when the warm margin of the thermal niche is reached and indicates that individual parameters such as thermoregulation coefficient and body condition, rather than demographic trends, are key indicators for an early detection of population extinction risk. The multipopulation approach implemented in our study allows to identify the niche edge that underlies species' vulnerability to global warming, and to identify populations suffering negative effects of climate change before demographic collapse. This might allow to plan appropriate mitigation measures and management strategies to avoid local extinctions
Sport practice and hemorrhoidal disease: results from a self-assessment questionnaire among athletes
Get PDFBackground: Hemorrhoidal disease (HD) is a common proctologic disease. Dietary and lifestyle play a role in the genesis of the disease or in its progression to more severe forms, although the exact mechanism is still not fully understood. We performed a pilot observational cross-sectional analytical association study to evaluate the possible association between sport activities and HD. Methods: We included subjects aged 18 years old or more, competitive and non-competitive, practicing at least one sport activity, at least twice a week. Data were collected using an online questionnaire, developed on the Microsoft Teams communication platform. Results: Out of the 312 study participants, 34% reported HD. Among subjects who practiced cycling or horseback riding, 57% reported suffering from HD; among those practicing bodybuilding, 48% complained of HD. In the multivariate logistic regression analysis, age and bodybuilding practice showed a statistically significant association with HD. Conclusions: Some sport activities could play a role in the onset or worsening of HD. Our results showed a positive association between cycling, horseback riding, bodybuilding, and HD occurrence. Given the numerous health benefits of physical activity, patients should be provided with correct information regarding the practice of sports in relation to their pathology
Caratterizzazione avanzati di componenti realizzati mediante Material Extrusion
No full textThis work aims to carry out a detailed investigation into the characterization methods of components made by Material Extrusion (MatEx) process. There are several articles in the literature that analyze the influence of process parameters on mechanical properties of MatEx components. However, traditional characterization methodologies are used, and these are not specifically developed for parts made by Material Extrusion process. Due to the layer-by-layer production mode, these components have some specific characteristics that are difficult to evaluate by classical mechanical characterization tests. Thus, advanced characterization of components made by Material Extrusion process has been conducted. Appropriately designed test methodologies have been developed for the mechanical evaluation of such components. Through these tests, the possibility to evaluate some characteristics of components with a high impact on their mechanical properties has arisen. Investigations on the presence of porosity, inter-laminar adhesion, and the impact of the size of manufactured components on their mechanical properties were conducted. Local characterization tests, tests for laminar structures, and process monitoring were the key tools used to evaluate these properties. The selected process parameters during the printing stage and the manufacturing strategies of the samples have been found to have a very high impact on the mechanical properties of the components. From the analysis of the obtained results, it was determined that careful characterization of components produced by material extrusion was needed, through tests specifically designed for such parts
Levilactobacillus brevis CD2 as a multifaceted probiotic to preserve oral health: results of a double-blind, randomized, placebo-controlled trial in healthy adults
Get PDFBackgroundA growing number of in vitro and in vivo studies suggest the application of probiotics as a natural approach to maintaining oral health. This double-blind, randomized controlled trial aimed to evaluate the efficacy of Levilactobacillus brevis CD2 (CNCM I-5566), a multifunctional probiotic frequently used in oral medicine, in preserving or improving several recognized oral health indicators.MethodsThirty consenting healthy adults were randomized to receive four lozenges per day of L. brevis CD2 probiotic (n = 15) or placebo (n = 15) over four weeks. Clinical parameters (full-mouth bleeding on probing (BoP) and plaque index (PI) scores) were recorded. Unstimulated saliva was collected to measure salivation rate, pH, and buffer capacity. Salivary biomarkers were analyzed, including glucose, D-lactate, and secretory immunoglobulins A (sIgA). Clinical and salivary parameters were assessed at baseline, after four weeks of intervention, and two weeks post-intervention. Wilcoxon rank-sum test and robust regression analysis were used for statistical comparisons. The possible mediating effect of PI on BoP changes was assessed.ResultsAfter four weeks, the probiotic group showed significant improvements in BoP and PI compared to baseline and placebo. The probiotic group had a higher salivation rate than baseline and placebo after four weeks of treatment and washout. While changes in salivary pH were not significant, buffering capacity increased in the probiotic group after four weeks of treatment and washout. Salivary glucose and D-lactate levels were lower in the probiotic group post-treatment and after washout. sIgA values increased and remained stable after washout in the probiotic group. No adverse effects were reported.ConclusionsThe treatment with L. brevis CD2 significantly improved clinical and salivary parameters, supporting its efficacy as a probiotic for oral health.Trial registrationClinicalTrials.gov, NCT06457724; Registered 7 June 2024 - Retrospectively registered; https://clinicaltrials.gov/study/NCT06457724?viewType=Table&page=452&rank=4512#study-overview
Synergistic Effect of Oxygen and Water on the Environmental Reactivity of 2D Layered GeAs
No full textWe investigated the reactivity of layered GeAs in the presence of oxygen or water using synchrotron-based X-ray photoelectron spectroscopy and ab initio calculations. By performing experiments at near-ambient pressure (up to 20 mbar), we gained detailed insights into the material’s stability under realistic conditions. GeAs showed limited reactivity with dry O2 and deaerated H2O. However, a small amount of humidity (Rw = 0.5% at T = 20 °C) in an O2 atmosphere significantly enhanced reactivity. This synergistic effect was well captured by density functional theory calculations, which revealed a strongly exothermic formation energy for the simultaneous chemisorption of O2 and H2O, compared to the adsorption of each molecule individually
Outcomes of Mechanical Thrombectomy in Patients With Ischemic Stroke and Heart Failure. A Systematic Review and Meta‐analysis
Get PDFBACKGROUND Patients with heart failure (HF) treated with mechanical thrombectomy (MT) for acute ischemic stroke were underrepresented in clinical trials on MT. Our systematic review and meta‐analysis aim to assess differences in outcomes between patients with HF and their counterparts without HF treated with MT for acute ischemic stroke.
METHODS A systematic review of the English language literature from inception up to March 7, 2024, was conducted using PubMed, Embase, Cochrane Library, and Web of Science databases. Studies focused on patients with and without HF who were treated with MT for acute ischemic stroke were included. The primary outcome of interest was the rate of modified Rankin Scale scores of 0–2 at 90 days. Secondary outcomes of interest included rates of 90‐day mortality, successful reperfusion, and symptomatic intracranial hemorrhage.
RESULTS
Of 5394 initially retrieved studies, 5 studies were included in the systematic review with a final population of 44 385 patients with ischemic stroke with and without HF treated with MT. Four studies were combined for the primary outcome and showed comparable rates of 0–2 modified Rankin Scale scores between patients with HF and patients without HF (odds ratio, 0.86 [95% CIs, 0.70–1.06]; P = 0.15). Ninety‐day mortality was significantly higher in the HF group (odds ratio, 1.92 [95% CIs, 1.66–2.23]; P<0.0001) although the sample size was small (n of study = 3) and only unadjusted estimates were used. Successful reperfusion and symptomatic intracranial hemorrhage rates were similar between the groups.
CONCLUSION In this systematic review and meta‐analysis, patients with HF experienced worse 90‐day mortality post‐MT. Our data encourage further research on MT outcomes in patients with large vessel‐occlusion ischemic stroke and concomitant HF
ESR Essentials: percutaneous bone consolidation—practice recommendations by the European Society of Musculoskeletal Radiology
No full textPercutaneous bone consolidation is increasingly used for the management of bone pain resulting from benign and malignant conditions. Percutaneous vertebroplasty was first performed in 1984 through the injection of polymethylmethacrylate (PMMA) bone cement directly into the cancellous bone of the vertebral body. Then, in the late nineties, balloon kyphoplasty was introduced consisting of the positioning of an inflatable balloon at the fracture site to create a cavity and restore the vertebral height, followed by PMMA injection. In recent years, more advanced techniques involving spinal implants combined with cement injection have also been developed in an attempt to restore vertebral body height. Vertebral augmentation techniques have been shown to be more effective for the treatment of vertebral fragility fractures than non-surgical management. Apart from osteoporotic fractures, vertebral augmentation has also demonstrated pain reduction and function improvement in patients with metastatic fractures. In extraspinal bone sites, percutaneous osteoplasty has proved helpful in treating both osteoporotic and pathological fractures, as well as in preventing tumor-related impending fractures. Recently, screw-mediated osteosynthesis has been described to withstand shear and rotational forces in the pelvic ring and long bones. We herein provide recommendations for the most common clinical situations that may benefit from such bone consolidation techniques