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Antifungal Potential of Pimpinella Anisum, Carum Carvi and Coriandrum Sativum Extracts. A Comparative Study With Focus on the Phenolic Composition
The present study aimed to characterize the phenolic extracts obtained from fruits of Pimpinella anisum L., Carum carvi L. and Coriandrum sativum L. (Apiaceae), and to assess their antifungal activity against main etiological agents involved in onychomycosis and other dermatomycoses (Trichophyton rubrum, T. mentagrophytes, Microsporum canis, M. gypseum and Candida albicans). Total phenolic and flavonoid contents varied from 3.80 ± 0.49 to 24.16 ± 0.82 mg gallic acid equivalents (GAE)/100 g dw, and 12.51 ± 0.14 to 37.75 ± 0.21 mg catechin equivalents (CE)/100 g dw, respectively. HPLC-DAD-ESI-Q-TOF-MS/MS analysis revealed the presence of chlorogenic acid, dicaffeoylquinic acid, luteolin and apigenin pentoside in all analysed samples. The extracts showed antifungal activity against all tested strains, with minimal inhibitory concentration (MIC) values in the range of 1.25-5 mg/mL. These results provide evidence that phenolic extracts obtained from fruits of P. anisum, C. carvi and C. sativum might be sources of antifungal agents with putative use in onychomycosis
Dynamics of broilers thighs chemical composition and energy content, under the influence of different technological temperatures during slaughter
Are the variations of temperature applied on certain key points quite significant in affecting the
ultimate compositional and nutritional features of the chicken broiler meat? This was the question
leading the research to further investigate three groups of carcasses (one control - CG, and two
treatments - T1 and T2) in relation with the single experimental factor – temperature - variations
on certain technological flow moments in the slaughterhouse: scalding station (CG:51-53⁰C,T1:53-
54⁰C,T2:55-56⁰C); chilling process (CG:1-4⁰C, T1:2-3⁰C; T2:1-2⁰C); sorting- packaging moment
(CG<2⁰C; T1:8-10⁰C; T2:6-8⁰C); storage before delivery (CG:0-2⁰C; T1 and T2:0-1⁰C). The
biological material comprised 150 ROSS-308 carcasses (50 per group), stored by refrigeration 1
day in slaughterhouse before shipping. Meat pieces weighing 50-100 grams, without skin, were cut
around femoral bone from the thighs musculature of each carcass, in order to form homogenous
samples per group; they were submitted to analytical laboratory assessment to quantify the main
nutritional compounds (water, dry matter, crude ash, total lipids and protein content, nitrogen free
extract) as well as gross energy value, using conventional A.O.A.C.-I.S.O. methods in 15
replications per compound. Thus, total dry matter varied between 28.34 g/100 g in CG and 28.81
g/100 g in T2 (P<0.05), while crude ash was found at 1.00g/100 g in CG, at 0.93g/100 g in T1, at
0.95 g/100 g in T2 (P<0.01 for T1, T2 vs. CG). Total lipids content was the most variable feature of
thigh meat, thus in CG reached 8.00 g/100g, while in T1 was 3.25% higher (8.26 g/100 g, P<0.001
vs. CG) and in T2 was 4.88% higher (8.39 g/100 g, P<0.001 vs. CG and P<0.05 vs. T1). Total
nitrogen matter slightly decreased from 18.78 g/100 g in CG till 18.59 g in T2, but the differences
were not big enough to generate reaching of 95% significance threshold. The gross energy content
was influenced by experimentally induced variable temperature, via lipids and nitrogen free extract
differences and was calculated at 154.04 kcal/100 g meat in CG, at 156.71 kcal/100 g meat in T1
and at 157.93 kcal/100 g sample in T2, that resulted in highly significant differences between
control and experimental treatments samples
Mouse models and Sars-Cov-2
Since December 2019, a novel coronavirus SARS-CoV-2 has emerged and rapidly spread throughout the
world, resulting in a global public health emergency. COVID-19 is causing a major once-in-a century global
pandemic. The emergences of coronaviruses have caused a serious global public health problem because
their infection in humans caused the severe acute respiratory disease and deaths. Much more serious than
SARS-CoV in 2002, the current SARS-CoV-2 infection has been spreading to more than 213 countries, areas
or territories and causing more than 31 million cases and 962,518 deaths (update september 2020). Intensive
research efforts have focused on increasing our understanding of viral biology of SARS-CoV-2, improving
antiviral therapy and vaccination strategies. The lack of vaccine and antivirals has brought an urgent need
for an animal model. The animal models are important for both the fundamental research and drug discovery
of coronavirus
Utilizarea curbelor matematice în procesul de obţinere a ornamentelor specifice elementelor decorative dintr-o grădină
The decorative and non-decorative elements from a garden can have different ornaments. For getting theseit may be used, various mathematical curves.Starting from this observation, the authors analyzed some mathematical curves from the perspective of used them within the Inventor computer program, with the goal of generated different ornaments using this software.Following this study, they arrived at some conclusions and recommendations, presented at the end of this paper, in the case of use mathematical curves by the Inventor software
Studies concerning world, European and national food security
The term food security appeared in the interwar period and over time there have been numerous attempts to define the notion. At global, European and national level, food security policies are regulated by a number of institutions and organizations with a supervisory, guiding and controlling role. The most important institutions dealing with food
security regulation worldwide are: WHO, FAO, IFPRI, at European level: European Commission, Council of the European Union and European Parliament, and at national level: MADR, ANPC, ANSVSA and the Ministry of Health. Food insecurity is a prolonged lack of “sufficient safe, nutritious food to maintain a healthy and active life” (FAO, 1996) and is generally caused by extreme poverty. In the context of food security, extreme poverty is synonymous with acute food shortages. The factors can be varied: from high prices, to economic recessions, natural disasters, political unrest and violent conflicts. Two thirds of the world's population vulnerable to food insecurity live in African countries,
or in countries with a large population such as: India, Bangladesh, Indonesia, Pakistan. In these countries, food security is correlated with both poverty and the many conflicts, we can add here environmental pollution, limited access to water resources. Regarding Romania, the agri-food stability is influenced by a series of factors starting from the reduction of the available agricultural areas, the precarious endowment of the Romanian farmer. A possible food crisis in our country will be generated, most likely by a mismanagement of an already existing vulnerability
Effect of nitrogen fertilizer on growth, flowering, fruiting and nodulation of three varieties of common bean in the arid region of aïn naga (Biskra, Algeria)
Field experiments were conducted to investigate the response of common bean (Phaseolus vulgaris L.) to nitrogen fertilizer. The main factor included the fertilizer (Granular Urea 46% N), was made up of two levels: no fertilization (0 kg/plot: control) and
fertilization (0.4 kg/plot), while the secondary factor was the variety (three varieties of common bean: Djedida, Nelson and Jalila). The experimental design was a randomized complete block design with split plot arrangement and replicated four times. The effect of
fertilization was evaluated during two development stages (flowering and fruiting) for each variety and this on the total dry biomass, the length of the aerial and root parts, as well as on the number of secondary roots. On the other hand, the combined effect of fertilization and variety was studied on some yield parameters per plant, such as the number of flowers, pods, seeds and the harvest index. In addition, the number of nodules at the end of seed maturation was evaluated. The results indicated that the nitrogen fertilizer application significantly reduced the root length, the number of nodules and secondary roots in most of the common bean varieties. However, fertilizer application significantly
increased dry matter in both flowering and fruiting stages, for the three studied
varieties. Pod number per plant and seed yield was increased by the application of
N fertilizer, depending on varieties and the parameters being measured. Djedida and Jalila varieties gave the best yield and can therefore be recommended to farmers. According to our results, the percentage of improvement by N fertilization on one parameter or another
does not exceed an average of 20%, compared to the control. Indeed, the effect of fertilization is positive and seems to increase the harvest index by 18% in Djedida and by 20% in Jalila, compared to non-fertilized plants. Unfertilized plants of the variety Nelson showed the highest ability to nodulate
Secondary irrigation infrastructure in Romania: influence of the water user`s associations modernization on the performance of their member farms
In this paper the authors undertook an analysis of the Water User’s Associations influence on the performance of their
members and on the agricultural sector. The existing crop irrigation infrastructure was built during the communist
period, before 1989. It was divided, since it’s been built, into primary and secondary infrastructure. After 1989, the
secondary infrastructure, usually built and located in key spots, in the proximity of water sources and farms, was
assigned to these units for maintenance and modernization. Water User’s Associations are non-profit economic units
that can be established by a minimum of ten members, agricultural units, and can benefit for receiving such an
infrastructure located in their proximity. Since Romania joined the E.U., some financial incentives have been developed
with the purpose of modernization of the primary and secondary irrigation infrastructure. Thus, the secondary
infrastructure can benefit from up to 1,000,000 Euro, with an intensity of 100% non-reimbursable for the modernization
of its entire serving area. In this paper the authors analyze the effectiveness of such an investment, a specific investment
amounting to 999,933 Euro. It will be shown how by carrying out the investment and modernizing the infrastructure, an
annual saving of 6,621,000 cubic meters of water will be achieved, as well as an annual saving of at least 463,200 lei.
As will be shown, the largest impact consists in the sufficient irrigation of the crops that leads to yields up to 4 times
higher per ha. The authors determined numerous indicators from the studies that are presented in the paper
In-depth assessment of new Ti-based biocompatible materials
The objective of the research is to obtain Ti20MoxSi (where x = 0, 0.5, 0.75, 1.0 wt %) alloys using the vacuum arc remelting (VAR) methods and to consider the effects of Mo and Si on physical-chemical, biological and mechanical biocompatibility. Through microstructure analysis the dendrites, grains, sub-grains, compounds have been confirmed; Mo adding determined the main β phase apparition and by increasing the Si content the dendritic microstructure was evidenced. The modulus of elasticity decreases with the amount of Si in the Ti20Mo alloys. The MTT assessment and fluorescent microscopy performed on fibroblasts and osteoblasts cells indicated a suitable cytocompatibility of the prepared alloys. Expression of osteopontin, metalloproteinases 2 and 9 (MMP2 and MMP9) in these areas into the periosteum and peri-implant highlight the bone mineralization. Mineralization and bone remodeling suggest a good biocompatibility of the implanted material with human tissue
Nematoda Ditylenchus dipsaci (Kühn, 1857) la cultura usturoiului în condiţii de grădină
In the Republic of Moldova to the cultivation of garden garlic, quite widespread is the stem parasitic nematode Ditylenchus dipsaci (Kühn, 1857). The extent of the invasion constitutes in many cases 78-90%, which often leads to total crop losses. In the vegetal tissue of the infested plants in the initial stages of ditylenchosis, collected during the summer period (June), was observed a monotypic primary popular of the vegetal tissue only with the species D. dipsaci (females, males, larvae, eggs). Subsequent observations have shown that in advanced stages of ditylenchosis the monotypic primary population is substituted by the heterotypic secondary population. In such tissue, the distribution of parasitic nematodes takes place as follows: parasitic nematodes D. dipsaci (females, males, larvae), account for 10.1% of the total; secondary parasitic nematodes (females, males, larvae) - 83.6%, most being of the order Rhabditida (species from the families Panagrolaimidae, Diplogasteridae, Cephaloidae); eggs-6.3%
Effect of farmer-herdsmen conflict on poverty status of farming households in Kwara State, Nigeria
This study examines the effect of farmer-herdsmen conflict on poverty status of crop farming households in Kwara State, Nigeria. Primary data was used for the study and a three stage sampling technique was adopted in the selection of the respondents. A structured questionnaire was used for the purpose of extracting needed information from
110 crop farming households selected for the study. The data collected were analyzed using Descriptive Statistics, Foster-Greer-Thorbecke (FGT) Index, and Tobit regression model. The result of prevalence of poverty among the farming households, who experienced conflict and those who didn’t in the study area, was 19.23% and 10.34%, while the intensity of poverty was 1.38 and 0.99%, respectively. The severity of poverty,
which measures the extent of poverty, shows poverty was more severe among the poor who experienced conflict with a poverty index of 0.0002 than the poor who didn’t experienced conflict, who had index of 0.0001. The Tobit regression model, which measured the effects of farmer-herdsmen conflict on poverty status of the farming household, indicates that the likelihood of being poor were more with large farming households, noneducated farming household heads, small farm size, low farm income households, low off-farm income and occurrence of conflict. The study therefore recommends that governments should designate some areas for the herdsmen as grazing field and also establish grazing reserves and communities in all the states, so as to
reduce farmers-herdsmen conflict