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Imputation of the response variable in survival analysis with Interval-Censored Data
No full textThis work is funded by national funds through FCT – Fundação para a Ciência e a Tecnologia, I.P., under the UID/00013: Centro de Matemática da Universidade do Minho (CMAT/UM) Program Contract, and the project reference 2023.14897.PEX (DOI: 10.54499/2023.14897.PEX).Handling interval-censored data in survival analysis presents signi cant challenges, as the exact time to the event is only known to fall within prede ned intervals. Common imputation strategies, such as those that use the lower bound, upper bound, or midpoint of the interval, often fail to capture the inherent uncertainty in the data, leading to biased or imprecise estimates. Prior studies have demonstrated the limitations of these approaches, particularly in accurately estimating survival probabilities and hazard ratios. To tackle these issues, we propose the Scaled Linear Redistribution Method, a new imputation technique aimed at overcoming the limitations of existing methods. The method redistributes imputed values within the interval, keeping their variation and basic statistical behavior. While our approach has not yet been implemented, it represents a promising direction for future research. We plan to evaluate its performance through a comprehensive simulation study, comparing its performance to that of traditional imputation methods and the Turnbull estimator, a widely used nonparametric method for interval-censored data
Geographic Information Systems (GIS) in Architecture and Urbanism Education
No full textIntegrating Geographic Information Systems (GIS) into architectural and urbanism education is increasingly recognized as a significant innovation for contemporary architectural and urban design pedagogies. Traditionally associated with geographers and urban planners, GIS is gaining traction in architecture due to its ability to integrate spatial data, visualize urban dynamics, and support evidence-based decision-making. Moreover, the increasing GIS capabilities to cross and visualize 3D geospatial data are a step forward in integrating GIS in architectural and urban design practices.
This paper reviews GIS adoption in architecture curricula with comparative case studies from Portuguese and international institutions found in scientific literature. Further, it presents the personal experience of over 13 years of professional and academic experience using GIS integrated in architectural and urbanism methodological processes.
GIS is analyzed as both a technological tool and a pedagogical strategy that fosters spatial literacy, critical thinking, and interdisciplinary collaboration. Despite its potential, GIS adoption in architecture remains inconsistent, with notable gaps in faculty training, infrastructure, and curricular integration. Recommendations are proposed to bridge these gaps and promote GIS as a core component of architecture and urbanism education in the digital age
Infertility-related stress and quality of life: The role of experiential avoidance
No full textInfertility is a disease with impact on the individuals’ lives which can be perceived as a stress-inducing experience. Higher levels of infertility-related stress have been associated with lower levels of quality of life. The aim of this study was to examine experiential avoidance as a pathway through which infertility-related stress is linked to quality of life in women with fertility problems. This cross-sectional study was conducted with a sample of 285 Portuguese women (M = 35.61; SD = 4.80) who completed a sociodemographic and clinical data sheet, and self-reported measures of infertility-related stress, experiential avoidance, and quality of life. The findings showed that infertility-related stress is positively associated with experiential avoidance and negatively associated with quality of life. Furthermore, experiential avoidance mediated the link between infertility-related stress and quality of life. Given that experiential avoidance may be a pathway leading to a worse adaptation, interventions focused on experiential avoidance may result in higher levels of quality of life in women dealing with fertility problems. Considering that this mechanism is a process underlying psychological inflexibility, which can be targeted by acceptance and commitment therapy, this therapy might be beneficial for women dealing with fertility problems, contributing to an improved quality of life
Fear of cancer recurrence, distress, and quality of life in adolescent and young adult cancer survivors
No full textAdolescents and young adult cancer survivors often experience high levels of fear of cancer recurrence (FCR), which significantly impacts their emotional well-being and quality of life. The lack of studies on this target population in Portugal leads to a gap of knowledge that informs the development of interventions and solutions aimed at AYA cancer survivors. This study aimed to analyze the moderating effect of FCR on the relationship between emotional distress and quality of life in AYA surviving cancer. This is a cross-sectional study including 96 participants between the ages of 15 and 25 at the time of diagnosis. Sociodemographic, clinical, and psychosocial characteristics were collected through a sociodemographic and clinical questionnaire, the FCR7 scale, the Hospital Anxiety and Depression Scale (HADS), and the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire Core-30 (EORTC QLQ-C30). We analyzed correlations between FCR and clinical, sociodemographic factors and tested the direct and indirect relationships between FCR, distress, and quality of life. The results indicated that high levels of FCR were associated with lower emotional functioning, and gender was the only sociodemographic variable significantly associated with FCR. Although anxiety was found to influence emotional functioning in AYAs, FCR did not moderate the relationship between anxiety and emotional functioning. This study allows us to gain more knowledge about the psychological impact of the disease on this population
Apontamentos do Jornal Oficial da União Europeia (2023)
No full textApresentam-se alguns apontamentos relativos a normas da atualidade do direito da União Europeia, por consulta ao Jornal Oficial da União Europeia no endereço http://eur-lex.europa.eu, em seleção da responsabilidade dos autores. Também por consulta a alguns documentos preparatórios no mesmo endereço e pequenas indicações de atualidade, sempre por referência a instituições
Editorial: Aging and work
No full textPopulation aging represents one of the most profound demographic transformations of the 21st century, with far-reaching implications for global labor markets. As working lives extend and workplaces become increasingly multigenerational, it is critical to understand how older adults adapt to evolving occupational demands. This Research Topic seeks to address these challenges through a multidisciplinary perspective, aiming to promote inclusive, sustainable, and meaningful career trajectories for aging populations
As iniciativas tributárias europeias e a agenda fiscal verde [artigo de imprensa]
No full textAo nível fiscal, a UE tem vindo a introduzir um conjunto de iniciativas tributárias que promovem os objetivos da agenda fiscal verde, ou seja, contribuindo para os objetivos climáticos da UE de reduzir as emissões de gases com efeito de estufa em pelo menos 55% até 2030 [...
Turismo de Bem-Estar: Microcredenciação em Turismo de Bem-Estar (Wellness) [comunicação oral: aula aberta]
No full textComunicação oral apresentada no evento Microcredenciação em Turismo de Bem-Estar (Wellness)
Sexual dysfunction in women with breast cancer: A systematic review
No full textPurpose
This systematic review aims to assess the prevalence, incidence, and risk factors for sexual dysfunction (SdF) in women with breast cancer (BC).
Methods
A systematic search was conducted in MEDLINE (PubMed), PsycINFO, Web of Science, and CINAHL to identity longitudinal, observational studies assessing SdF in women with BC. Data extraction followed PRISMA guidelines. The Joanna Briggs Institute checklist was used to assess methodological quality. Results were narratively synthesised.
Results
A total of 16 studies involving 4058 women met the inclusion criteria. Overall, the reported prevalence of SdF ranged from 17.5% before BC diagnosis to 86% after 6 months of hormone therapy. Only one study reported incidence data. The six most commonly studied SdF domains were desire, arousal, lubrication, orgasm, satisfaction, and dyspareunia. A significant number of risk factors associated with different dimensions of SdF were identified.
Conclusion
SdF is highly prevalent in women with BC, particularly in the first year after diagnosis and treatment. These findings strongly suggest that SdF should be routinely assessed as part of survivorship care protocols. Due to the scant data on incidence rates and the wide variability in reported risk factors, significant gaps remain in our understanding of the onset and progression of SdF in patients with BC. Well-designed cohort studies are needed to better establish the incidence and aetiology of SdF in this patient population