Open Access Publications (Univ. de Genève)
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Space sets time inside the cell nucleus
No full textHow would we fit two meter of a thread do it into a 0.006mm space? Would it be easy to find along this thread important pieces that should interact? Those are the approximate measures of the human DNA and its enclosing nucleus, and the answer to the questions above have direct implications on how to activate genes at the right time and place
E-skin: the future of sustainable & recyclable wearable electronics
No full textAn electronic “skin” can find applications in health care, robotics, and prosthetics, and can benefit the well-being, economy, and sustainability of our society. A sustainable futuristic electronic skin with superior stretching, self-healing, recycling, and reconfiguration capabilities has been developed by combining scientific advances in materials, electronics, mechanics and chemistry
Floppy proteins and the hidden sequences they use to communicate
No full textOur cells are filled with proteins. These proteins usually have a specific structure which help them to make the specific interactions we need to live. But how do short, floppy regions of proteins make such tight and specific interactions despite lacking any structure
Outcomes of SARS-CoV-2–Positive Youths Tested in Emergency Departments: The Global PERN–COVID-19 Study
No full textThe Global Pediatric Emergency Research Network (PERN)–COVID-19 Study sought to understand the risk factors for severe SARS-CoV-2 infections in youth by conducting a cohort study including children, with early or mild stages of disease, seeking emergency department (ED) care. The study identifed that risk factors such as age, underlying chronic illness, and symptom duration may be useful to consider when making clinical care decisions
Intersectional Inequalities in Science
No full textThe US scientific workforce is not representative of the population. Our analysis utilizes millions of scientific papers to study the relationship between scientists and the science they produce. We find a strong relationship between the characteristics of scientists and their research topics, suggesting that diversity changes the scientific portfolio with consequences for career advancement for minoritized individuals
Mitochondria as microlenses in the eye – the evolution of an improved camera sensor
No full textThe neurons of the eye that detect light must be very sensitive. They also need ample energy to continuously signal the light they see, so they contain many mitochondria—however, mitochondria scatter light. In our recent study, we show how evolution has found a way to have the best of both worlds: Why not build mitochondria into a lens that helps, rather than hurts, visual sensitivity
Genetically reprogramming biological clocks: one step closer to the Fountain of Youth
No full textImagine telling explorers of the New World that the Fountain of Youth was hidden in their cells… That\u27s probably what Kristen C. Browder\u27s team could say after successfully reversing the biological clock of living mice. According to their results, the secrets of rejuvenation seem to be buried in the heart of each of our cells, in other words, in our genes
One step closer to having diabetes under control
No full textType 1 diabetes is a chronic disease that requires patients to control their blood sugar levels daily. A drug being tested on newly diagnosed patients could improve their quality of life by protecting and stimulating the pancreatic cells responsible for blood sugar regulation
The AK423 antibody recognizes human actin by western blot
Get PDFThe AK423 antibody, raised against Dictyostelium actin, recognizes human actin by western blot; AE765, AK692, AO233 and AO234 do not
AF397, AK652, AN193 and AV442 antibodies recognize a GFP-tagged Golgi protein by immunofluorescence
Get PDFAF397, AK652, AN193 and AV442 antibodies against the GFP protein recognize a GFP-tagged human B4GT1 protein by immunofluorescence in paraformaldehyde-fixed HEK cells