Open Access Publications (Univ. de Genève)
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Nature favors simplicity and symmetry in biological forms
No full textWhy do symmetric and regular shapes abound in biology? Using arguments based on algorithmic information theory, we explain why a preference for simple shapes often occurs in biological systems. Our theory is validated via predicting the shape frequencies for naturally occurring protein assemblies, non-coding RNAs, self-assembled tile shapes, and a cell cycle mathematical model.
The Light of Earendel – The Most Distant Star Yet Observed
No full textThe gravity of massive objects can magnify background objects, making them appear larger and brighter. Precise alignment between a background star and a foreground lens leads to extreme magnifications, allowing individual stars to be detected at great distances. This technique has recently revealed the most distant star yet observed, which existed when the universe was only 900 million years old
Mountain flowers awe the eye and puzzle the botanist
No full textUsually, we identify plants by their showy and delicate flowers. Because flowers are selected to be more attractive compared with leaves, stems, or the hidden roots for most species. However, sometimes, when flowers from different but related species are similar, even the botanists might feel confused and misidentify them, which might lead to mistakes. So how can we identify them correctly
Stress for parents can translate into resilience for their children
No full textOne of the major challenges we face today is making sure there\u27s enough food for everyone in the world. Crop diseases are making it difficult to grow enough food, therefore challenging our goal of ending world hunger. We found that treating wheat seeds with fungus Trichoderma can protect the wheat crop from diseases, not only in their current generation but also in descending ones.
How HIV-infected cells use immune checkpoints to evade the human immune system
No full textThe human immune system is very effective in eliminating pathogens that attack us in everyday life. However, in the case of HIV infection, it fails to clear all infected cells, resulting in a disease that remains incurable to date. Our study reveals that HIV-infected cells express higher levels of immune checkpoint markers and \u27do not kill me\u27 signals, helping them evade immune detection
Source-to-sink controls on modern fluvial sands in the Pantanal back-bulge basin (Brazil)
Get PDFSedimentological processes are underexplored in retro-arc basin segments of source-to-sink systems, particularly in the distal back-bulge depozone. The extant Pantanal Basin of Latin America is a large sub-tropical continental back-bulge for which the boundary conditions on riverine sedimentation (tectonics, climate, phytogeography) are reasonably understood. Here, we use a new database of riverbed sand samples (n = 97) to investigate the modern provenance of the Pantanal Basin. Petrographic analysis of grain-mounted thin sections and Gazzi-Dickinson point counting were used to assess the framework composition of the sands, and a pour point analysis based on geographic information systems (GIS) defined the hinterland geological environment for each sample. Six provenance domains were defined: (a) lowlands, (b) Amazon craton, (c) Rio Apa craton, (d) plateau, (e) South Paraguay Belt, and (f) North Paraguay Belt. Most Pantanal samples are quartzose non-orogenic detritus (Qt88\F5\L7). Rivers draining the Paraguay Belt highlands carry more lithic grains derived from carbonate parent rocks. The occurrence of plagioclase grains is rare. However, river sands where >30% of the total assemblage was K-feldspar were present downstream of foliated metamorphic outcrops of the Rio Apa craton. Sand relatively rich in fine K-feldspar grains in the medial Taquari River megafan were attributed to channel avulsion, incision, and reworking of floodplain deposits. Statistical analysis suggests that bedrock lithology and average annual rainfall are important controls on fluvial sands in the Pantanal Basin, with watershed slope, temperature, and dilution playing secondary roles in the spatial distribution of dominant grain types. This study provides new actualistic data that aim to improve interpretations of the geological record
Recombinant nanobodies detecting the human cardiac troponin proteins by ELISA
Get PDFWe tested the capacity of antibodies RB733, RB734, RB766, RB767, RB768, RB769, RB770, RB771, RB772 and RB773 to recognize by ELISA three different molecular forms of the human cardiac troponin T isoform 6 (cTnT): an N-terminal peptide (Nter-cTnT), the full-length cTnT protein (FL-cTnT) and the cardiac troponin I-T-C complex (ITC-complex). Our results show that RB734 specifically recognizes the N-terminal region of cTnT as well as the full-length protein alone and the ITC-complex. RB767, RB770, RB771, RB772 and RB773 recognize the full-length cTnT protein alone or in the ITC-complex but not the N-terminal peptide. RB766, RB768 and RB769 recognize the ITC-complex but not cTnT or cardiac troponin I (cTnI) proteins
The RB395 antibody recognizes a Dictyostelium AplA peptide by ELISA
Get PDFThe recombinant antibody RB395 detects by ELISA a synthetic peptide from the Dictyostelium AplA protein (amino acids 370-388)
AD822, AW199, AW200 and AW201 antibodies against the human Fas receptor (CD95) bind the surface of HEK293 cells as revealed by flow cytometry
Get PDFThe recombinant antibodies AD822, AW199, AW200 and AW201 bind HEK293 cells expressing the human Fas receptor protein as assessed by flow cytometry
