Open Access Publications (Univ. de Genève)
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How mixed-breed dogs resolve the “horoscopes” surrounding dog breeds
No full textDog breeds are iconic, serving as familiar examples for how genetic selection can produce a diverse array of biological traits from appearance to physiology to behavior. Genome-wide analysis and large-scale surveys of companion dogs—pedigreed and mixed-breed—re-evaluates how much a dog’s breed genetically influences how they look and behave
The Lingering Shadow of Redlining: Fossil Fuel Power Plants and Air Pollution
No full textHistorically redlined communities in the U.S. today have lower home values, poorer health, and greater exposure to environmental hazards. Our research found that between 2000 and 2019, fossil fuel power plants were 31% more likely to be built near and upwind of neighborhoods that were redlined in the 1930s
Visualizing the initial steps of blood clotting by SARS-Cov2 Spike protein
No full textThe SARS-Cov-2 Spike protein has been attributed to many peculiar symptoms of COVID-19, like blood clotting and tissue damage. Using the cutting-edge cryo-electron tomographic technique, we directly observed SARS-Cov2 Spike proteins acting on the platelet surface. Our finding explains why SARS-Cov-2 can significantly jeopardize blood clotting compared to other coronaviruses
Low and Mighty: How Low-Affinity Antibodies Boost Cancer Immunotherapy
No full textAntibodies, nature’s guided missiles, are designed to bind to their targets with high precision. The tighter they bind, the better they’re thought to perform. But what if we’ve been wrong all this time? Our research suggests that antibodies with a looser grip can sometimes be more effective. This unexpected finding could open new avenues for improved antibody-based therapies
How to make a kilonova: Finding a path for cosmic alchemy
No full textAstronomers recently discovered a pair of stars circling each other (a binary star) that will eventually end its life in an explosion so powerful it creates gold. These explosions create large amounts of gold and other heavy metals but their formation has proven difficult to model. This discovery shows how double-stars hold the key for understanding how precious metals are made in the cosmos.
Sedimentologika: a community-driven diamond open access journal in sedimentology
Get PDFSedimentologika is a community-driven Diamond Open Access scientific journal for the publication of work in the broad area of sedimentology and stratigraphy. The journal aims to provide a platform to the academic community and broader society, offering and guaranteeing permanent free publication and free access to peer-reviewed scientific studies focusing on all types of sedimentary processes, deposits, and environments across all spatial and temporal scales, on Earth or any other planetary body. It will publish high-quality research that will advance the field of sedimentary science, and will encourage multidisciplinarity, new teaching practices, tools and methods, and progress in accessibility to science. Sedimentologika is part of an ongoing broader Diamond Open Access movement in geosciences aspiring freedom from the financial barriers and pressures of private publishing houses, to provide direct and equal access to science for all citizens, scientists, and institutions worldwide. The published material will include research, review, methodology and opinion articles, which will be free to share, as the authors will retain the copyright of all the submitted material. Manuscripts will be published in English. Authors can attach a second abstract in a language of their choice, further allowing local communities, students, or decisional bodies to access, at least, a summary of the latest research, thus reducing potential language barriers. Sedimentologika follows Open Science principles to promote ethical dissemination and accessibility of science and knowledge, following high equity, diversity and inclusion standards. Sedimentologika emerged as a solution for the scientific community to sidestep structural inequality of the academic publishing system that is becoming financially unsustainable to its payers (authors, funding agencies), and to commit to bibliodiversity. The objective is to ensure that scientific findings remain accessible to all in order to keep advancing research and informing society on how we understand sedimentology and stratigraphy in the world around us. Sedimentologika is driven by the academic and scientific community for the community and society, promoting self-governance and adapting to the needs expressed by the community
Geochronology of reworked ash and its implications for accommodation space variations in distal foreland basins, McMurray Formation, Alberta, Canada
Get PDFA bentonite bed consisting of reworked volcanic ash from the Barremian to Aptian lower McMurray Formation is dated using chemical abrasion thermal ionization mass spectrometry (CA-TIMS) on zircon. The bentonite bed is from a cored interval in the McKay Paleovalley in the northern Athabasca Oil Sands Region of Alberta, Canada. Deposition of the lower McMurray Formation took place in the distal portion of the Western Canada Sedimentary Basin early in the Cretaceous-to-Paleocene phase of widespread contractional deformation in the Canadian Cordillera. A 30 g sample of volcanic ash yielded >10,000 very small (<50 µm) zircon grains with the vast majority (~99.7%) being highly abraded and clearly detrital. Twenty-six sharply faceted grains were sufficiently large to be mounted for laser ablation inductively coupled plasma mass spectrometry (LA-ICPMS) analysis, which yielded seven Lower Cretaceous dates. These Lower Cretaceous grains were further analyzed using CA-TIMS. The five youngest CA-TIMS dates agree with a weighted mean of 121.51 ± 0.11 Ma which is conservatively interpreted as a maximum depositional age (MDA). The good agreement between the five zircon dates indicates the MDA is probably the depositional age. This study demonstrates that with careful analysis of zircon populations, high-confidence MDAs can be derived even from reworked ash beds that are dominated overwhelmingly by detrital zircon. The date from this study overlaps a previously published MDA of 121.39 ± 0.27 Ma for the top of the lower McMurray Formation in Firebag Tributary in the northeastern Athabasca Oil Sands Area. The overlapping dates establish a widespread chronostratigraphic surface within the northern Athabasca Oil Sands Area. Both ages are from ash beds preserved in coal seams, suggesting that the coal-bearing interval is a regional marker bed and that the ash beds may form an intraformational datum. Further, the occurrence of the ash beds in the McMurray Formation in close proximity to regional flooding surfaces suggests that tectonic activity in the emerging Canadian Cordillera influenced accommodation space variations in the distal portions of the adjacent foreland basin
Exposer en bibliothèque : enjeux, méthodes, diffusion
Get PDFCet ouvrage (exposer en bibliothèque : enjeux, méthodes, diffusion), accessible également sur OpenEdition Books, est coordonné par Emmanuèle Payen, cheffe du service de développement culturel et actualité à la Bibliothèque publique d’information de Paris et qui est également commissaire d’exposition
Usages et utilisabilité d’un outil de découverte en contexte académique : évaluation de l’expérience utilisateur de swisscovery UNIGE
Get PDFSwisscovery est un outil de découverte basé sur la solution Primo d’Ex Libris. Il permet à ses utilisateurs, principalement les membres des universités et hautes écoles suisses, d’effectuer des recherches dans les collections de 490 bibliothèques et d’accéder à une quantité de documents encore inégalée en Suisse, grâce à un nouveau réseau national de prêt entre bibliothèques (PEB). Le catalogue met à l’honneur l’exploration des ressources numériques, avec l’intégration de nombreuses bases de données d’articles scientifiques et e-books et la facilité d’accès aux documents en plein-texte.
Ce compte-rendu, basé sur un travail de master en Sciences de l’information[1] examine l’expérience qu’ont les utilisateurs de swisscovery UNIGE, la plateforme gérée par la Bibliothèque de l’Université de Genève, un peu plus d’un an après son déploiement fin 2020. Plus spécifiquement, il s’est agi de comprendre comment les publics-cibles du catalogue se sont approprié l’outil, comment il s’insère dans leurs pratiques de recherche documentaire et quels soucis d’utilisabilité ils ont pu rencontrer dans leurs cheminements sur swisscovery.
Pour ce faire, des méthodes à la fois qualitatives (tests utilisateurs, observations en bibliothèque) et quantitatives (analyse des données d’usage de swisscovery UNIGE) ont été utilisées. Les résultats révèlent un outil globalement fonctionnel et apprécié, mais aussi certains problèmes d’utilisabilité récurrents, déjà rencontrés ailleurs dans la littérature sur l’évaluation de l’utilisabilité de Primo.
Ces résultats permettent de fournir une série de recommandations destinées à optimiser les paramétrages et l’accompagnement à l’utilisation de swisscovery UNIGE. Notamment, ils ouvrent à une réflexion sur la fonction d’un « outil de découverte » axé sur le numérique et l’exploration, qui entre en tension avec celle d’un « catalogue de bibliothèque » encore utilisé par beaucoup pour identifier et accéder à des documents physiques
The RB393, RB394 and RB395 antibodies do not recognize the Dictyostelium AplA protein by western blot
Get PDFThe recombinant antibodies RB393, RB394 and RB395 do not detect by western blot the AplA protein