Jichi Medical University Institutional Repository
Not a member yet
1006 research outputs found
Sort by
Patients with advanced chronic kidney disease in the regional care setting: Current problems and future directions
Get PDF地域中核病院である当院において，高度腎機能低下（eGFRが30ml/min/1.73m2未満）の保存期慢性腎臓病（CKD）患者は171名，79.0±10.8（平均±標準偏差）歳，男性51％で，３年前との比較で患者数は54％（80歳以上は65％）増加していた。原疾患は，腎硬化症42.7%，糖尿病性腎臓病（DKD）36.3%，心不全7.0%，糸球体腎炎5.3%で，3＋以上の蛋白尿を有する症例はDKDで高率であり腎機能不良の要因であると考えられた。最近６年間の透析導入患者は184名で，70.1±11.9歳，男性67％，原疾患は，DKD 48.4％，腎硬化症31.0％，糸球体腎炎9.2％で，DKDは腎硬化症より有意に低年齢だった。透析導入目的で紹介をうけた患者は73名で，紹介時のeGFRは10.6±5.8ml/min/1.73m2，導入までの期間は平均１年１ヶ月だったが，eGFRが 20ml/min/1.73m2以上の患者では平均３年５ヶ月だった。当院でeGFR>30 ml/min/1.73m2の時点から継続診療した患者は24名で，eGFR<30 ml/min/1.73m2の時点から透析導入までの期間は平均５年２ヶ月だったが，3＋以上の高度蛋白尿を呈したDKD患者８名のそれは平均２年２ヶ月であった。糖尿病診療の強化，高齢者への対策，病診連携の促進，CKDに関する啓蒙が必要であると考えられた。departmental bulletin pape
Clinical and Radiological Outcomes after External Fixator as a Definitive Fixation in Patients with Unstable Pelvic Ring Fracture
Get PDFIntroduction
External fixators are commonly applied to pelvic ring fractures mainly for temporary stabilization. However, there are no reports that provide patient reported outcome measures. We report clinical and radiological outcomes following external fixation (EF) performed as a definitive fixation method in patients with unstable pelvic ring fractures, including complications and physical/mental health status assessment using the Short-Form 36-item Health Survey (SF-36).
Methods
Data of patients with unstable pelvic ring fractures were retrospectively analyzed using an electronic medical database. Inclusion criteria were patients with unstable pelvic ring fracture who underwent EF as a definitive fixation method and followed up for a minimum of 12 months.
Results
This study included 25 patients. The grade of pelvic ring fracture was type B in 8 cases (32%) and type C in 17 cases (68%). The mean Majeed score was 84.0 ± 19.3. Moreover, 15 patients were rated“ excellent,” 7“ good,” 1“ fair,” and 2“ poor.” The outcome of physical function according to the SF-36 was significantly worse than that of the average Japanese population.
Conclusion
Favorable functional outcomes were reported by 88% of patients after EF as a definitive fixation method for unstable pelvic ring fracture. EF is a potential treatment option for unstable pelvic ring fractures in physically fragile patients or patients with other complications.departmental bulletin pape
Determination of agonist-dependent and -independent interaction between dimerized receptor and b-arrestin 2
Get PDF自治医科大学博士（医学）令和2年度doctoral thesi
The pharmacotherapeutic effects and molecular mechanism of β-catenin inhibitor for heart failure
Get PDF自治医科大学博士（医学）令和2年度doctoral thesi
