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看護師長のやりがいを構成する要素
No full text本研究は、一般病院で勤務する看護師長が仕事を遂行する上で、やりがいとなっている要素を明らかにすることを目的とした。方法は、甲信越3県で公益財団法人日本医療機能評価機構による病院機能評価の認定を受けている一般病院48施設に勤務する看護師長318名を対象に、無記名自記式質問紙調査を行った。因子分析の結果、7因子を抽出した。看護師長のやりがいを構成する要素は、第1因子は《医療チームとの円滑な関係》α＝.924、第2因子は《師長としての承認》α＝.918、第3因子は《良質なケアの実践》α＝.857、第4因子は《仕事と生活の両立》α＝.870、第5因子は《スタッフの看護への良い評価》α＝.892、第6因子は《目指す目標の達成》α＝.862、第 7 因子は《自身のキャリア開発機会の確保》α＝.920 であった。49 項目全体のCronbachαは.955と高く、内的整合性が高いことが確認された。The purpose of this study was to clarify the elements comprising the sense of fulfi llment that head nurses employed at general hospitals gain through the execution of their work. The method was an anonymous self-administered questionnaire survey of 318 head nurses working in 48 general hospitals that were certifi ed through the evaluation of hospital practices by the Japan Council for Quality Health Care in three（3）prefectures in the Koushinetsu region. Seven（7）factors were extracted through a factor analysis. The factors comprising fulfi llment in head nurses were as follows: factor 1 “smooth relationship with the medical team” with α=.924, factor 2 “recognition as a superior” with α=.918, factor 3 “practicing high-quality care” with α=.857, factor 4 “work-life balance” with α=.870, factor 5 “good evaluation of nursing staff ” with α=.892, factor 6 “achievement of set goals” with α=.862, and factor 7 “securing opportunities for personal career development” with α=.920. The Cronbachʼs α for all 49 items was high at .955, confi rming good internal consistency.departmental bulletin pape
佐久大学・国際看護論におけるタイ王国での演習と学び
No full text佐久大学では、4年次の選択科目として国際看護論（2単位、60時間）を履修できる。演習としてタイ王国チョンブリ県、ブラパ大学看護学部（Burapha university, Faculty of Nursing,Chonburi, Thailand）にて、講義、施設見学などを2019年8月19日～28日までの10日間実施した。本科目は、国際的な視点から諸外国の健康問題および心身の健康に影響を与える社会・経済、および文化・伝統的な背景を検討しつつ看護活動のあり方を学ぶため、「日本とタイの相違点、および類似点について、事前学習した範囲において説明をすることができる」「現地での学習・交流を通してコミュニケーション能力を高め、国際的な視点を広げる」という到達目標を掲げている。履修学生12名は、演習を通して①日本で自分たちが学修している看護との相違点、類似点について気付き、②タイの看護の背景となっているタイ王室との関係、文化・歴史的経緯について理解を深め、③ブラパ大学のバディの学生との交流を通して英語でのコミュニケーションの必要性を認識し、④国際的な演習プログラムを通して看護観が大きく広がったことを感じていた。departmental bulletin pape
The AGP-PPAR gamma axis promotes oxidative stress and diabetic endothelial cell dysfunction
No full textAlkyl-glycerophosphate (AGP) accumulates in atherogenic oxidized-LDL and human atherosclerotic plaques and is a potent agonist of peroxisome-proliferator-activated receptor-gamma (PPAR gamma). Recent studies suggest a potential regulatory role for PPAR gamma in endothelial nitric oxide synthase (eNOS) expression/activation and nitrogen oxide (NO) generation in the vascular endothelium. Importantly, eNOS-induced NO and advanced glycation end-products (AGEs) are involved in blood-vessel damage, and diabetic patients exhibit high serum NO and AGE levels; however, the effect of AGP on NO- and AGE-mediated endothelium dysfunction remains unknown. Investigation of the AGP-specific effects on NO- and AGE-mediated dysfunction and the underlying molecular mechanisms revealed that AGP upregulated eNOS expression and NO production, and that eNOS silencing and gamma antagonism inhibited AGP-mediated eNOS upregulation and NO production. Moreover, AGP-PPAR gamma-axis-mediated NO production promoted the generation of reactive oxygen species and AGE formation. These results suggested that AGP plays a significant role in the initiation/progression of diabetes-related atherosclerosis through PPAR gamma activation. (C) 2018 Elsevier B.V. All rights reserved.ArticleMOLECULAR AND CELLULAR ENDOCRINOLOGY. 473:100-113 (2018)journal articl
The Use of Electrospun Organic and Carbon Nanofibers in Bone Regeneration
No full textThere has been an increasing amount of research on regenerative medicine for the treatment of bone defects. Scaffolds are needed for the formation of new bone, and various scaffolding materials have been evaluated for bone regeneration. Materials with pores that allow cells to differentiate into osteocytes are preferred in scaffolds for bone regeneration, and porous materials and fibers are well suited for this application. Electrospinning is an effective method for producing a nanosized fiber by applying a high voltage to the needle tip containing a polymer solution. The use of electrospun nanofibers is being studied in the medical field, and its use as a scaffold for bone regeneration therapy has become a topic of growing interest. In this review, we will introduce the potential use of electrospun nanofiber as a scaffold for bone regenerative medicine with a focus on carbon nanofibers produced by the electrospinning method.ArticleNANOMATERIALS. 10(3):562 (2020)journal articl
Applications of Carbon Nanotubes in Bone Regenerative Medicine
No full textScaffolds are essential for bone regeneration due to their ability to maintain a sustained release of growth factors and to provide a place where cells that form new bone can enter and proliferate. In recent years, scaffolds made of various materials have been developed and evaluated. Functionally effective scaffolds require excellent cell affinity, chemical properties, mechanical properties, and safety. Carbon nanotubes (CNTs) are fibrous nanoparticles with a nano-size diameter and have excellent strength and chemical stability. In the industrial field, they are used as fillers to improve the performance of materials. Because of their excellent physicochemical properties, CNTs are studied for their promising clinical applications as biomaterials. In this review article, we focused on the results of our research on CNT scaffolds for bone regeneration, introduced the promising properties of scaffolds for bone regeneration, and described the potential of CNT scaffolds.ArticleNANOMATERIALS. 10(4):659 (2020)journal articl
Inhibition of CASK Expression by Virus-mediated RNA Interference in Medial Prefrontal Cortex Affects Social Behavior in the Adult Mouse
No full textArticle信州医学雑誌 69(1): 45-52(2021)journal articl
A trapezoidal wing equivalent to a Janatella leucodesma's wing in terms of aerodynamic performance in the flapping flight of a butterfly model
No full textWing planform is one of the most important factors for lift and thrust generation and enhancement in flapping flight. In a previous study based on a simple numerical model of a butterfly, we found that the wing planform of an actual butterfly (Janatella leucodesma) is more efficient than any rectangular or trapezoidal wing planform. In the present study, we make a hypothesis that the efficient aerodynamic performance of a butterfly's wings can be reproduced by the following four geometrical parameters of wing planform: aspect ratio, taper ratio, position of the rotational axis for the geometric angle of attack, and sweepback angle. In order to test this hypothesis, we explore a trapezoidal wing planform equivalent to an actual butterfly's wing planform in terms of aerodynamic performance in a parameter space consisting of these four parameters. We use a simple butterfly model composed of two rigid thin wings and a rod-shaped body and calculate the aerodynamic performance of the model by an immersed boundary-lattice Boltzmann method to find such a trapezoidal wing planform. As a result, we find a trapezoidal wing planform which gives almost the same lift, thrust, pitching moment, power, and power-loading coefficients as an actual butterfly's wing planform. Furthermore, in the free flight of the butterfly model with pitching motion control, the flight behavior of the model with the resulting trapezoidal wing planform is almost the same as that with an actual butterfly's wing planform.ArticleBIOINSPIRATION & BIOMIMETICS.14(3):036003(2019)journal articl
