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    障害をどう学ぶか : 知識からつながりへ、「違う」から「同じ」へ

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    Article教職研究, 10:21-42 (2019)departmental bulletin pape

    《後水滸傳》的構思

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    清朝出現了《水滸》的續篇,主要有三個,就是《水滸後傳》、《後水滸傳》和《蕩寇志》。其中《後水滸傳》失傳了很久,待上世紀80年代重新露面了,傳本只有一個,是大連圖書館珍藏的。我們雖然可以由影印本或排印本窺見其真面目,但難免存在問題。筆者首先談一下有關問題,然後要討論《後水滸傳》的構思如何。Article信州大学人文科学論集 (6): 131-141(2019)departmental bulletin pape

    観光客の視点で考える仙北市観光と田沢湖

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    Article国立大学法人信州大学 教育学部自然地理学研究室『2017年度地理学野外実習報告書Ⅹ 秋田』(2019). p.39-46.research repor

    FVA 論争について

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    Article信州大学経法論集 6:123-141(2019)departmental bulletin pape

    Autonomous xenogenic cell fusion of murine and chick skeletal muscle myoblasts

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    Cell-cell fusion has been a great technology to generate valuable hybrid cells and organisms such as hybridomas. In this study, skeletal muscle myoblasts were utilized to establish a novel method for autonomous xenogenic cell fusion. Myoblasts are mononuclear myogenic precursor cells and fuse mutually to form multinuclear myotubes. We generated murine myoblasts (mMBs) expressing green fluorescent protein (GFP) termed mMB-GFP, and the chick myoblasts (chMBs) expressing Discosoma red fluorescent protein (DsRed) termed chMB-DsRed. mMB-GFP and chMB-DsRed were cocultured and induced to differentiate. After 24h, the multinuclear myotubes expressing both GFP and DsRed were observed, indicating that mMBs and chMBs interspecifically fuse. These GFP(+)/DsRed(+) hybrid myotubes were able to survive and grew to hyper-multinucleated mature form. We also found that undifferentiated mMB-GFP efficiently fuse to the chMB-DsRed-derived myotubes. This is the first evidence for the autonomous xenogenic fusion of mammalian and avian cells. Myoblast-based fusogenic technique will open up an alternative direction to create novel hybrid products.ArticleANIMAL SCIENCE JOURNAL. 88(11):1880-1885 (2017)journal articl

    Tectonic constraints to Cretaceous magmatic arc deduced from detrital heavy minerals in northeastern Japan – evidence from detrital garnets, tourmalines and chromian spinels

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    Tectonic histories of sedimentary basins in the Cretaceous Japan arc have been assessed to understand the response of the Asian continental margin to the oblique subduction of the Paleo-Pacific (i.e. Kula or Izanagi) Plate beneath the Asian continent during the Early Cretaceous and that which subducted orthogonally in the Late Cretaceous. In the Lower Cretaceous Kuji Group (Santonian–Campanian) of the Kitakami Massif in northern Japan, sandstone petrography and chemistry of detrital heavy mineral grains were performed on sandstones to assess the tectonic environment on the basis of provenance analysis.Sandstone petrography results suggest that the material of the Kuji Group was derived mainly from areas of a Cretaceous volcanic belt (Rebun-Kabato Belt) and from a Jurassic accretionary complex (North Kitakami Terrane), which was intruded by Cretaceous granite, adjacent to the depositional basin. The chemical composition of detrital garnets suggests a North Kitakami Terrane origin, and detrital tourmalines are considered to have been derived mainly from meta-sedimentary rocks. The composition of detrital chromian spinels are compositionally diverse and mainly derived from tholeiitic and intra-plate basalts showing high TiO2 (>about 1.0 wt%) and island arc basalts with moderately low TiO2 (1.0 > TiO2 > 0.5 wt%) and high Cr#. Latter chromian spinels can be considered as a record of island arc activity including high Mg-andesite in Early Cretaceous time. Because adequate source rocks of the spinels are elusive near the basin compared with those of detrital garnets and tourmalines, these rocks are believed to have been disturbed by Cenozoic tectonics and eroded and covered by newly formed volcanic and sedimentary rocks.Comparison of chemical composition of the chromian spinels between Lower and Upper Cretaceous deposits in northern Japan indicates that chromian spinels with very low TiO2 (<0.5 wt%) prevail in the Lower Cretaceous (Aptian–Albian). In contrast, chromian spinels showing moderately low TiO2 predominated in the Upper Cretaceous (Santonian–Campanian). This clear difference suggests the change of oceanic plate motion around Japan arc promoted the change of source rock assemblage and the arc volcanic activity in mid-Cretaceous time. Thus the characteristics of detrital heavy mineral composition of the Kuji Group give the key to clarify the interaction between the swaying of young and hot plate and development of the Cretaceous island arc in eastern Asian margin.ArticleCRETACEOUS RESEARCH.48:39-53(2014)journal articl

    Comparison of administration of platelet concentrates suspended in M-sol or BRS-A for pediatric patients(小児患者におけるM-solまたはBRS-Aに浮遊させた血小板製剤投与の比較)

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    信州大学(Shinshu university)博士(医学)雑誌に発表。TRANSFUSION. 58(12):2952-2958 (2018); doi:10.1111/trf.14917.Thesis小嶋 俊介. Comparison of administration of platelet concentrates suspended in M-sol or BRS-A for pediatric patients(小児患者におけるM-solまたはBRS-Aに浮遊させた血小板製剤投与の比較). 信州大学, 2019, 博士論文.doctoral thesi

    Panobinostat inhibits the proliferation of CD34+CD38-cells under stimulation of hematopoietic growth factors on AGM-S3 cells in juvenile myelomonocytic leukemia(Panobinostatは若年性骨髄単球性白血病におけるCD34陽性CD38陰性細胞のAGM-S3上での造血因子依存性増殖を抑制する)

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    信州大学(Shinshu university)博士(医学)雑誌に発表。PEDIATRIC BLOOD & CANCER. 65(11):e27261 (2018); doi:10.1002/pbc.27261.Thesis倉田 敬. Panobinostat inhibits the proliferation of CD34+CD38-cells under stimulation of hematopoietic growth factors on AGM-S3 cells in juvenile myelomonocytic leukemia(Panobinostatは若年性骨髄単球性白血病におけるCD34陽性CD38陰性細胞のAGM-S3上での造血因子依存性増殖を抑制する). 信州大学, 2019, 博士論文.doctoral thesi

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