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レクチン様酸化LDL受容体(LOX-1)遺伝子欠損は大動脈外膜における線維芽細胞及びコラーゲンの増殖を抑制し腹部大動脈瘤破裂を促進する
Ehime University (愛媛大学)博士(医学)thesi
ポリアモルフィズムの熱力学
A substance in a solid state can take more than a crystalline phase. For example, ice, a solid form of water, has nineteen crystalline phases. Each solid state has a different structure because water molecules are located on discrete lattice points with different symmetry. Then, the problem is whether a liquid state without a long-range order can take more than a single phase. Water has been considered to have two forms; one is low density and the other high density. The problem is named polyamorphism because of the involvement of polyamorphs. An occurrence of polyamorphism has been pointed out on a thermodynamic basis. At the beginning of this century, experimental evidence of polyamorphism was given for liquid phosphorus. This exciting experimental finding has revived the old theory of polyamorphism and activated the hunting of substances exhibiting polyamorphism. This review picks up essential substances stimulating the subsequent theoretical development. Therefore, the author also explains the original and recent theories in some detail. We have now attained a consensus regarding water polyamorphism through the theories. The author also mentions the crucial problems that remain unanswered.departmental bulletin pape