Open Library Archives of Kagawa University (OLIVE)
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The sincerity of care giver learned from the comic “DORAEMON” : A clinical psychological perspective
No full textThe comic “DORAEMON” by Fujiko F. Fujio is very popular in Japan and other Asian countries. This work depicts universal human psychology. Since all Japanese are familiar with its contents, it is considered useful as an example or teaching material for learning the basic attitudes necessary for care givers. SEWASHI, the character in the work, is an egoistic person, but care givers are also in danger of dominating care users with their own views of humanity and values. DORAEMON is not a well‐made robot. However, that is why it is able to empathize with NOBITA, an underachiever. Care givers may be able to demonstrate empathy like DORAEMON toward users by being aware that they too will die and by being aware of their own weaknesses and imperfections.departmental bulletin pape
Effect of aspirin on G0/G1 cell cycle arrest and microRNA signatures in pancreatic adenocarcinoma cells
No full text香川大学Kagawa University博士（医学）Background/aim: Anti-inflammatory drugs, such as aspirin, have attracted attention as anticancer agents that can be applied to standard chemotherapy for pancreatic cancer. This study aimed to examine the antitumour effects and possible fundamental mechanisms of aspirin in pancreatic cancer cells.Materials and methods: We appraised the antitumour effects of aspirin on cell proliferation and tumour growth, cell cycle distribution, apoptosis, signalling pathways, angiogenesis-related proteins, and phosphorylated receptor tyrosine kinases (p-RTKs) and identify miRNAs associated with its antitumour effects.Results: Aspirin inhibited cell proliferation in pancreatic cancer cell lines and induced G0/G1 cell cycle arrest by decreasing the expression of cyclin D1. Aspirin inactivated glycogen synthase kinase (GSK)-3β but had no effect on the p38 mitogen-activated protein kinase (MAPK) pathway, p-RTKs, or angiogenesis-related molecules. Aspirin treatment statistically increased the expression of 274 miRNAs in PANC-1 cells and 30 miRNAs in PK-8 cells and suppressed the expression of 294 miRNAs in PANC-1 cells and 13 miRNAs in PK-8 cells.Conclusion: Aspirin inhibited the proliferation of pancreatic cancer cells and induced cell cycle arrest. Aspirin also inactivated GSK-3β but not the p38 MAPK pathway. Thus, aspirin may be used in combination with chemotherapeutic agents for pancreatic cancer.doctoral thesi
Using natural language processing techniques to detect adverse events from progress notes due to chemotherapy
No full text香川大学Kagawa University博士（医学）Objective: In recent years, natural language processing (NLP) techniques have progressed, and their application in the medical field has been tested. However, the use of NLP to detect symptoms from medical progress notes written in Japanese, remains limited. We aimed to detect 2 gastrointestinal symptoms that interfere with the continuation of chemotherapy-nausea/vomiting and diarrhea-from progress notes using NLP, and then to analyze factors affecting NLP.Materials and methods: In this study, 200 patients were randomly selected from 5277 patients who received intravenous injections of cytotoxic anticancer drugs at Kagawa University Hospital, Japan, between January 2011 and December 2018. We aimed to detect the first occurrence of nausea/vomiting (Group A) and diarrhea (Group B) using NLP. The NLP performance was evaluated by the concordance with a review of the physicians' progress notes used as the gold standard.Results: Both groups showed high concordance: 83.5% (95% confidence interval [CI] 74.1-90.1) in Group A and 97.7% (95% CI 91.3-99.9) in Group B. However, the concordance was significantly better in Group B (P = .0027). There were significantly more misdetection cases in Group A than in Group B (15.3% in Group A; 1.2% in Group B, P = .0012) due to negative findings or past history.Conclusion: We detected occurrences of nausea/vomiting and diarrhea accurately using NLP. However, there were more misdetection cases in Group A due to negative findings or past history, which may have been influenced by the physicians' more frequent documentation of nausea/vomiting.doctoral thesi
Ⅰ．インターナショナルオフィス全体に関わる報告
No full text１．インターナショナルオフィス概要２．香川大学の国際化の基本方針と重点戦略課題３．2022年度インターナショナルオフィス年間行事（2022年４月～2023年３月）４．Trilateral Symposium on SDGs - 2022 Online Research Seminar -
香川大学・チェンマイ大学・国立嘉義大学合同シンポジウム
2022年度オンラインセミナーの開催報告について５．EJEA国際カンファレンス2022を後援開催６．学長・インターナショナルオフィス長表敬訪問７．インターナショナルウィーク８．留学生のつどい９．グローバルクラスルーム10．グローバル・インスピレーション・イニシアティブ開催11．独立行政法人国際協力機構（JICA）との連携12．留学生宿舎13．三木高校インターンシップ受入れdepartmental bulletin pape
Ⅲ．留学生の受け入れに関わる報告【留学生支援と国際交流】
No full text４．留学生対象各種進学説明会５．課外教育行事６．JASSO中島財団助成による2021年度留学生地域交流事業７．国際交流活動８．SDGs関連活動９．就職支援プログラム10．相談業務departmental bulletin pape
Practical activities to increase breakfast intake rate through government-academia collaboration : Investigation of the effectiveness of “Bingo de onigiri” and factors affecting breakfast intake
Get PDF児童・生徒の朝食摂取率の上昇を目的に、香川県教育委員会の「生活リズムでパワーUP事業」の一環として、自分でおにぎりを作る活動を実施した結果、朝食摂取率が上昇した。朝食摂取状況は睡眠関連因子や生活習慣、家庭環境に関する因子と有意に関連した。実践後は、朝食作成意欲が上昇し、朝食作りの実践者が増加する行動変容が確認された。レシピ集の活用及び役立ち度は、約70%以上を示し本実践の有益性が認められた。本研究は、香川県教育委員会生涯学習・文化財課の「生活リズムでパワーUP」事業の助成金により実践したものである。departmental bulletin pape