Open Library Archives of Kagawa University (OLIVE)
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Abstracts of papers presented at the 75th Annual Meeting
Get PDF香川県東部に“ミナミヌマエビ”はいるのか？ / 石井良典紫外線硬化樹脂包埋透明骨格標本の作製とそれを用いた観察実践効果に関する研究 / 江川碧唯, 松本一範Julidochromis transcriptus における子殺し行動に関する研究 / 井上陽稀, 松本一範ハダカアリ属における雌雄モザイク個体の外部形態と内部構造 / 吉澤樹理香川大学幸町キャンパスにおけるアサギマダラの誘致 / 玉川晋二郎, 北林雅洋, 筧善行, 片岡郁雄journal articl
Morphometry of choroid plexus epithelial cells in neurodegenerative diseases
Get PDFThe choroid plexus not only secretes the majority of cerebrospinal fluid but also controls the circadian rhythm, which can be impaired in the presence of neurodegenerative diseases. In addition, many studies have reported the contribution of choroid plexus abnormalities to the pathogenesis of neurodegenerative diseases, including Alzheimer's disease (AD). Formalin-fixed paraffin-embedded blocks were obtained from the lateral ventricles of the brains of four subjects with AD, four with vascular dementia, four with Parkinson's disease, three with multiple system atrophy, and five control patients with unremarkable neuropathological findings. They were sectioned and routinely stained with hematoxylin and eosin. Morphological analysis of epithelial cells in 10 high-power fields or a total area per case was conducted using digital images. There were no significant changes in any of the measurements: epithelial cell area, long and short axes, and ratio of the epithelial cell area to total stained area among the five groups. However, a simple linear regression analysis of epithelial cells in 20 patients showed that age was significantly correlated with the cell area, long axis, and short axis but not ratio. There were no effects of hypertension, diabetes mellitus, or calcification in the stroma on the measurements. These findings indicate that age was associated with the cell area and size in choroid plexus epithelial cells, whereas no significant changes in any epithelial cell measurements were present in neurodegenerative diseases.journal articl
ELISA for deoxynivalenol using a hapten antigen different from the immunogen
Get PDFDONに対するモノクローナル抗体（DON.3抗体）を用いたELISAで、モノクローナル抗体作製時の免疫原と同じ構造のハプテン抗原であるDON‐15O‐HS‐OVAを固相抗原とした場合とこれと異なる8位のカルボニールに架橋基が結合しているDON‐oxime‐蛋白質を固相抗原とした場合の測定感度を比較した。その結果、免疫原と異なるハプテン抗原を用いた場合7.7倍感度が向上した.すなわち、免疫原と異なるハプテン抗原を用いることでELISAの感度を上げられることを明らかにした。In an ELISA using a monoclonal antibody against DON (DON.3 antibody), the sensitivity of the assay was compared between DON‐15O‐HS‐OVA, a hapten antigen with the same structure as the immunogen used to generate the monoclonal antibody, and DON‐oxime‐protein, which has a cross‐linked carbonyl group attached at position 8, which is a different hapten antigen as the immunogen, as the solid‐phase antigen. The sensitivity of competitive indirect ELISA was improved by 7.7‐fold when a hapten antigen different from the immunogen was used. In other words, the sensitivity of ELISA can be increased by using a hapten antigen different from the immunogen.departmental bulletin pape
A study on the creation of the educational platform under flexible inter‐university cooperation (2)
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The report on the first ‘Geo Art Jr. meister course’ of Kagawa University
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How students perceive the “Introduction to academic research” course : Student survey results
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