Repositorio académico de acceso abierto (Univ. Autonóma de Chile)
Not a member yet
7149 research outputs found
Sort by
Comparative effects of different types of exercise on health-related quality of life during and after active cancer treatment: A systematic review and network meta-analysis
No full textBackground: The positive influence of most types of exercise has been reported repeatedly, but what the most effective exercise approaches are for improving health-related quality of life (HRQoL) in people with cancer remains unknown. The aim of this systematic review and network meta-analysis was to synthesize the evidence from intervention studies to assess the effects of different types of exercise on HRQoL during and after cancer treatment. Methods: MEDLINE, SPORTDiscus, the Cochrane Library, Web of Science, and Scopus were searched for randomized controlled trials aimed at testing the effects of exercise interventions meant to improve HRQoL in people with cancer. Separate analyses were conducted for HRQoL as measured by general and cancer-specific questionnaires. We also evaluated whether the effects of exercise were different during and after cancer treatment in both the physical and mental HRQoL domains. Results: In total, 93 studies involving 7435 people with cancer were included. Network effect size estimates comparing exercise intervention vs. usual care were significant for combined exercise (0.35, 95% confidence interval (95%CI): 0.14–0.56) for HRQoL as measured by general questionnaires, and for combined (0.31, 95%CI: 0.13–0.48), mind–body exercise (0.54, 95%CI: 0.18–0.89), and walking (0.39, 95%CI: 0.04–0.74) for HRQoL as measured by cancer-specific questionnaires. Conclusion: Exercise programs combining aerobic and resistance training can be recommended to improve HRQoL during and after cancer treatment. The scarcity and heterogeneity of these studies prevents us from making recommendations about other exercise modalities due to insufficient evidence. © 2023BBP; Consejería de Educación, Cultura y Deportes-JCCM; European Social Fund Plus, ESF, (2020-PREDUCLM-16746); Universidad de Castilla-La Mancha, UCLM, (2020-PREDUCLM-15596); European Regional Development Fund, ERDF, (SBPLY/17/180501/000533)Universidad Autónoma de Chil
Post-COVID green supply chain management of used products: a study towards awareness for vaccination
No full textIn the era of digital media, there is rapid spread of information. During coronavirus (COVID-19) pandemic situation, the government and other administrative bodies were highly dependent on media outlets, as direct contact was not feasible. Visual communication tools are used to spread awareness and encourage people towards vaccination. The circulation of wrong information may lead to confusion, which may cause denying the vaccine. There was a need to know the extent for contribution of visual communication tools for spreading correct information and motivating the society towards vaccination in post COVID times. In the present study, survey questionnaires were framed specific to which media (print or digital) was more effective to deliver the correct information to the targeted audience. The present study objectives to answer the questions through a survey of 312 people of different age groups, and the data was collected about their families. The obtained data was tested through hypothesis, and fact-checked was performed adopting analysis of variance (ANOVA). The results from the study highlighted that different age groups prefer different mediums of communication. The reach and adoption of digital media have tremendously increased, and it helped to achieve the sustainable development goals (SDGs) by efficient green supply chain management (GSCM) of daily plastic and paper wastage during post-pandemic
Competências interculturais a partir de uma abordagem ética intercultural na formação inicial de profissionais em ciências da saúde. Um desafio inevitável
No full textChile is a culturally diverse country, and this population must face difficulties related to health. This essay aims to reflect on intercultural competencies from an intercultural ethical approach, in the initial training of professionals in health sciences. The initial training in health sciences shows that health is lacking and decontextualized from the cultural reality. In order to evolve in this area, it is imperative to train professionals in intercultural competencies from an intercultural ethical approach. This will contribute to the recognition and understanding of otherness from their own culture, based on the relationship and exchange of experiences, knowledge, wisdom, among others. This requires intercultural dialogue between professionals and experts belonging to different health systems, in order to co-construct from health and disease. This will allow a timely and adequate response to health demands. It will also provide quality and dignified health care and attention. In effect, it will mitigate inequalities and injustices, while providing a fuller life to people living in a culturally diverse society. © 2023, Universidad de Chile - Centro Interdisciplinario de Estudios en Bioetica. All rights reserved.Universidad Autónoma de Chil
Lost in Corporate Translation: How Firms Mediate between Social Mobilization and Regulatory Intervention in the Extractive Sector
No full textFirms should be considered as actors that potentially mediate between social movement pressures and policy outcomes. This article shows that at the mining project level, social mobilization can generate important changes in corporate practices toward nearby communities, and that these practices can undermine the cohesion of social movement coalitions advocating for regulatory intervention or reform, thus limiting their ability to make compelling claims on the state. In this way, company interpretations of and responses to protest are an important mediating process that conditions civil society efforts to activate state institutions in their favor. This argument extends recent work on the social foundations of regulation in Latin America by including corporate actors. The article is based on a comparative case study of the Pascua Lama/Veladero mining projects in both Argentina and Chile, using both secondary sources and primary field research. © The Author(s), 2023. Published by Cambridge University Press on behalf of the University of Miami.Social Sciences and Humanities Research Council of Canada, SSHRC; Fondo Nacional de Desarrollo Científico y Tecnológico, FONDECYT, (3200013); Consejo Nacional de Investigaciones Científicas y Técnicas, CONICET; Agencia Nacional de Investigación y Desarrollo, ANIDUniversidad Autónoma de Chil
Primary Validation of the Submandibular Skinfold as an Anthropometric Measurement of Cardiometabolic Risk in People with Intellectual Disabilities
No full textThe accumulation of body fat is an important cardiometabolic risk factor; however, there is no consensus about which measure is more reliable for the assessment of cardiometabolic risk in people with intellectual disabilities. The aim of the present study was to primarily validate the submandibular skinfold as an anthropometric measurement of cardiometabolic risk in children, adolescents, and adults with intellectual disabilities, using a cross-sectional study made up of 131 people (67.2% men) with mild and moderate intellectual disability. The cardiometabolic risk indicators used were: body mass index (kg/m2), neck circumference (cm), waist circumference (cm), calf circumference (cm) and waist-to-height ratio. Moderate correlations were demonstrated between the submandibular skinfold measure and the anthropometric measurements analyzed in the three age categories, showing the highest correlation (r = 0.70) between the submandibular skinfold and BMI in the adolescent group and waist-to-height ratio in adults. The implementation of the submandibular skinfold measurement is suggested as an easy, fast, and minimally invasive anthropometric measurement as part of the physical and nutritional evaluation for the assessment of cardiometabolic risk in people with intellectual disabilities.Universidad Autónoma de Chil
Nonlinear acoustic characterization of heterogeneous plasticity in bent aluminium samples
No full textKnowledge of the state of plastic deformation in metallic structures is vital to prevent failure. This is why non-destructive acoustic tests based on the measurement of first order elastic constants have been developed and intensively used. However, plastic deformations, which are usually heterogeneous in space, may be invisible to these methods if the variation of the elastic constants is too small. In recent years, digital image correlation techniques, based on measurements carried out at the surface of a sample, have been successfully used in conjunction with finite element modeling to gain information about plastic deformation in the sample interior. Acoustic waves can penetrate deep into a sample and offer the possibility of probing into the bulk of a plastically deformed material. Previously, we have demonstrated that nonlinear acoustic methods are far more sensitive to changes in dislocation density than linear ones. Here, we show that the nonlinear Second Harmonic Generation method (SHG) is sensitive enough to detect different zones of von Mises stress as well as effective plastic strain in centimeter-size aluminium pieces. This is achieved by way of ultrasonic measurements on a sample that has undergone a three-point bending test. Because of the relatively low stress and small deformations, the sample undergoes plastic deformation by dislocation proliferation. Thus, we conclude that the nonlinear parameter measured by SHG is also sensitive to dislocation density. Our experimental results agree with numerical results obtained by Finite Element Method (FEM) modeling. We also support the acoustic results by X-ray Diffraction measurements (XRD). Although intrusive and less accurate, they also agree with the acoustic measurements and plastic deformations in finite element simulations.Universidad Autónoma de Chil
Análisis poblacional in silico del haplotipo CLOCK rs3749474T-rs4864548A y su relación con obesidad
No full textIt has been suggested that the rs3749474T/rs4864548A haplotype of the CLOCK gene increases the risk of obesity, but the population variability of these alleles and the haplotype is unknown. This research aims to determine the linkage between the rs3749474T and rs4864548A alleles from the database of 1000Genomes to confirm the existence of the TA haplotype polymorphisms of these alleles and their frequency in five macro populations. Linkage disequilibrium and haplotype frequencies for 2504 individuals from 26 populations were analyzed using the r2 statistic and Fisher's exact test. There is a high frequency of the TA haplotype in Latin America (44.8%), a high linkage disequilibrium (r2= 0.92) worldwide between these alleles, a high differentiation between macro populations, and a high homogeneity. The evidence warrants further studies on the association between this haplotype and the risk of obesity and overweight in Latin American populations. © 2023, Medwave Estudios Ltda. All rights reserved.Universidad Autónoma de Chil
Future burden of non-communicable diseases attributable to overweight in Chile: a multistate life table modeling study
No full textBackground: Previous studies have quantified the current burden of diseases attributable to overweight in Chile. However, no study has estimated the attributable burden of overweight in the future. Herein, we estimated the potential impact of different trajectories in the prevalence of overweight on the incidence and mortality from non-communicable diseases (NCDs) in Chilean adults from 2019 to 2030. Methods: A multistate life table modelling was used to estimate the business-as-usual (BAU: if the current rate of increase in BMI persist through the next 11 years; i.e., 0.4% per year from 2003 to 2017) and three counterfactual scenarios (1: the increase rate of overweight is reduced by half; 2: maintanance of the current prevalence of overweight; 3: the prevalence of overweight is reduced by 6.7%) over a 11-year simulation period for burden of NCDs attributable to overweight in Chilean adults aged 20 to 80 years. The model inputs included nationally representative data of body mass index, national official demographic records, NCDs from the Global Burden of Disease study in 2019, and relative risks from a published meta-analysis. Results: If the current trends of increase in overweight are maintained in Chile, approximately, 669 thousand cases and 117 thousand deaths from NCDs will occur from 2020 to 2030. In case the increase rate of overweight is reduced by half during this period, around 7 thousand cases and 1.4 thousand deaths from NCDs would be prevented, while achieving no increase in the prevalence of overweight would avert 10 thousand cases and 2 thousand deaths. In the optimistic scenario of reducing the prevalence of overweight by 6.7% until 2030, approximately 25 thousand cases and 5 thousand deaths from NCDs would be prevented. Conclusion: We estimated that the number of NCDs cases and deaths that could be avoided by decreasing the prevalence of overweight in Chilean adults. Preventive programs aimed to reduce overweight may have a high impact on the future burden of NCDs in Chile. © 2023, The Author(s).Desarrollo e Innovación; National Health Survey; Universidad de Santiago de Chile, (032287DF_Ayudante); Vicerrectoría de Investigación, Desarrollo e Innovación, VRIDEIUniversidad Autónoma de Chil
Factors associated with the incidence and worsening of back pain during the first wave of COVID-19 in Brazil
No full textThe article aims to estimate the incidence and worsening of back pain (BP) during the first wave of COVID-19 in Brazil, as well as to investigate demographic, socioeconomic factors and associated changes in living conditions. ConVid – Behavior Research, applied between April and May 2020, was used as data source. The number and distribution of respondents who developed BP and those who had a worsening of the preexisting problem, their 95% confidence in-tervals and Pearson’s Chi-square test were estima-ted. The odds ratio of developing BP or worsening a preexisting problem was also estimated using multiple logistic regression models. Pre-existing BP was reported by 33.9% (95%CI 32.5-35.3) of respondents and more than half (54.4%; 95%CI 51.9-56.9) had worsened. The cumulative incidence of BP in the first wave of the pandemic was 40.9% (95%CI 39.2-42.7). Being a woman, the perceived increase in housework and the frequent feeling of sadness or depression were associated with both outcomes. Socioeconomic factors were not associated with any of outcome. The high incidence and worsening of BP during the first wave reveal the need for studies in more recent periods, given the long duration of the pandemic. © 2023, Associacao Brasileira de Pos - Graduacao em Saude Coletiva. All rights reserved.Universidad Autónoma de Chil
Improving mechanical properties and antibacterial response of α/β ternary Ti–Ta alloy foams for biomedical uses
No full textThis study investigates the potential of Ti–Ta–Sn alloys for biomedical applications due to their excellent mechanical properties and biocompatibility, with a particular focus on their use in trabecular bone replacement. This work aims to analyze the influence that of Sn has on the mechanical properties and antibacterial response of α−β ternary Ti–13Ta–xSn (x:3, 6, 9, and 12 at.%) alloy foams. The Ti-based alloys were designed considering three aspects; (i) final microstructure, (ii) alloying element types, and (iii) thermodynamics while using MAAT and ThermoCalc software. The alloys were obtained by mechanical alloying, with used milling times being 30 h for Ti–13Ta–3Sn, 10 h for Ti–13Ta–6Sn, 10 h for Ti–13Ta–9Sn, and 15 h for Ti–13Ta–12Sn. The foams were obtained using NaCl as the space holder (50 v/v% porosity) and consolidated by a hot pressing method at 780 °C for 30 min, applying a load of 40 MPa. Both the Staphylococcus aureus ATCC 6538 strain and Escherichia coli ATCC 8739 strain were used to evaluate the antibacterial responses of Ti-based alloy foams. The Ti-based alloy foams were composed mostly by a mix of α and β-phases. The metallic foams exhibited relative homogeneous pore distribution with a size between 100 and 450 μm and having an average porosity slightly higher than 50%. The samples showed elastic modulus values between 1 and 2 GPa, compressive yield strengths over 150 MPa, and microhardness over 450 HV. All Ti-based alloy foams showed no antibacterial activity nor bacterial adhesion, indicating that there is bacterial adhesion inhibition. © 2023 The AuthorsFONDEQUIP, (11220774); Fondo Nacional de Desarrollo Científico y Tecnológico, FONDECYT, (1190797, 1230620); Agencia Nacional de Investigación y Desarrollo, ANIDUniversidad Autónoma de Chil