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    20896 research outputs found

    ナチュラルキラー細胞の生体内恒常性維持におけるタンパク質脱リン酸化酵素2Aの役割

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    富山大学博士(薬科学)Article富山大学・富医薬博甲第484号・新澤 結・2025/03/25 公表論文 1.Shinzawa Y, Hara D, Shinguryo Y, Yokoyama S, Kawada M, Hayakawa Y. PP2A negatively regulates NK cell T-bet expression and anti-tumor effector function. Int Immunol. 2024;37(2):97-107. doi: 10.1093/intimm/dxae057. PMID: 39404747. 2.Shinzawa Y, Sasaki SI, Iwabuchi S, Hashimoto S, Kawada M, Hayakawa Y. Protein phosphatase 2A inhibitor modulates natural killer cell homeostasis in peripheral tissues. Biochem Biophys Res Commun. 2024;31:741:151020. doi: 10.1016/j.bbrc.2024.151020. PMID: 39577078

    骨格筋萎縮により誘発される認知障害発症メカニズムに関する研究

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    富山大学博士(薬科学)Article富山大学・富医薬博甲第489号・長瀬 綸沙・2025/03/25 公表論文 1. Nagase T, Tohda C. Skeletal muscle atrophy-induced hemopexin accelerates onset of cognitive impairment in Alzheimer's disease. J Cachexia Sarcopenia Muscle. 2021 Dec;12(6):2199-2210. doi: 10.1002/jcsm.12830. PMID: 34658156. 2. Iki-Nagase T, Tohda C. Skeletal muscle atrophy induces memory dysfunction via hemopexin action in healthy young mice. Biochem Biophys Res Commun. 2024 Nov 12:733:150606. doi: 10.1016/j.bbrc.2024.150606. PMID: 39208645

    Regulation of non-canonical EphA2 activation in cellular stress responses and epithelial mesenchymal transition

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    富山大学博士(薬科学)Article富山大学・富医薬博甲第490号・宋 磊鑫・2025/03/25・★論文非公開★ 公表論文 1.Zhou Y, Oki R, Tanaka A, Song L.X, Takashima A, Hamada N, Yokoyama S, Yano S, Sakurai H. Cellular stress induces non-canonical activation of the receptor tyrosine kinase EphA2 through the p38-MK2-RSK signaling pathway. J Biol Chem. 2023 May;299(5):104699. doi: 10.1016/j.jbc.2023.104699. PMID: 37059179. 2.Song L.X, Yang F, Wang Z.T, Yang L, Zhou Y. Ginsenoside Rg5 inhibits cancer cell migration by inhibiting the nuclear factor-κB and erythropoietin-producing hepatocellular receptor A2 signaling pathways. Oncol Lett. 2021 Jun;21(6):452. doi: 10.3892/ol.2021.12713. PMID: 33907562

    細胞恒常性維持機構Autophagyから導く妊娠高血圧腎症の病態解明と治療法開発

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    富山大学博士(医学)Article富山大学・富医薬博甲第475号・古田 惇・2025/03/25 公表論文 1.Furuta A, Shima T, Kawaguchi M, Yamaki-Ushijima A, Yasuda I, Tsuda S, Yoneda S, Higashisaka K, Cheng S.B, Matsumoto K et al. The Autophagy-Lysosomal Machinery Enhances Cytotrophoblast–Syncytiotrophoblast Fusion Process. Reprod. Med. 2022:3(2):112–126. doi: 10.3390/reprodmed3020010 2.Furuta A, Shima T, Yoshida-Kawaguchi M, Yamada K, Yasuda I, Tsuda S, Yamaki-Ushijima A, Yoneda S, Higashisaka K, Cheng S.B et al. Chloroquine is a safe autophagy inhibitor for sustaining the expression of antioxidant enzymes in trophoblasts. J Reprod Immunol. 2023 Feb:155:103766. doi: 10.1016/j.jri.2022.103766. PMID: 3647013

    Research and Applications of Fractional Order Differential Evolution

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    富山大学博士(工学)Article富山大学・富理工博甲第253号・王愷昱・2025/3/25202

    Peripheral intravenous catheter insertions in older inpatients-Characteristic features of venous cannulation and its associated complications

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    富山大学博士(看護学)Article富山大学・富医薬博乙第113号・北田 素子・2025/02/27・★論文非公開★ 公表論文 1.Kitada M, Yamamura S, Ninomiya A, Kabashima M, Tateno K, Hori E. Characteristics of Peripheral Intravenous Catheter Cannulation in Older Japanese Inpatients. J Infus Nurs. 2025 Jan-Feb;48(1):25-31. doi: 10.1097/NAN.0000000000000564. Epub 2024 Dec 26. PMID: 39760875 2.Kitada M, Yamamura S, Hori E. Subcutaneous edema as a potential cause of catheter failure in older inpatients receiving peripheral parenteral nutrition. Drug Discov Ther. 2024 Jul 9;18(3):160-166. doi: 10.5582/ddt.2024.01029. Epub 2024 Jun 15. PMID: 3888060

    ヒト絨毛膜由来間葉系幹細胞(CMDC)の分離

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    富山大学博士(医学)Article富山大学・富医薬博甲第471号・森 亮介・2025/03/2

    強心配糖体によるSLCトランスポーターの発現変化が引き起こす抗がんメカニズムの解明

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    富山大学博士(薬科学)Article富山大学・富医薬博甲第488号・加藤 瑞希・2025/03/25 公表論文 1.Fujii T, Katoh M, Ootsubo M, Nguyen O. T. T, Iguchi M, Shimizu T, Tabuchi Y, Shimizu Y, Takeshima H, Sakai H. Cardiac glycosides stimulate endocytosis of GLUT1 via intracellular Na+ ,K+ -ATPase α3-isoform in human cancer cells. J Cell Physiol. 2022 Jul;237(7):2980-2991. doi: 10.1002/jcp.30762. PMID: 35511727. 2.Katoh M, Fujii T, Tabuchi Y, Shimizu T, Sakai H. Negative regulation of thyroid adenoma-associated protein (THADA) in the cardiac glycoside-induced anti-cancer effect. J Physiol Sci. 2024 Apr 1;74(1):23. doi: 10.1186/s12576-024-00914-7. PMID: 38561668

    Safe insertion of pedicle screws and achievement of reliable initial stability in spinal surgery

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    富山大学博士(医学)Article富山大学・富医薬博甲第495号・二川 隼人・2025/09/26 公表論文 1.Futakawa H, Nogami S, Seki S, Kawaguchi Y, Nakano M. Evaluation of Triggered Electromyogram Monitoring during Insertion of Percutaneous Pedicle Screws. J Clin Med. 2022 Feb 23;11(5):1197. doi: 10.3390/jcm11051197. PMID: 3526828

    欠損値処理と安定性評価を用いた動的ネットワークバイオマーカー理論に関する研究

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    富山大学博士(工学)Article富山大学・富理工博甲第268号・米澤翔汰・2025/9/26202

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