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    20896 research outputs found

    NMRメタボローム法の確立と応用:芍薬と骨砕補の品質標準化を目指した成分分析

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    富山大学博士(薬科学)Article富山大学・富医薬博甲第434号・董 昱卓・2023/09/2

    モノクローナルACPA、CCP-Ab1の可変領域におけるN型糖鎖は実験的関節炎の増悪を来す

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    富山大学博士(医学)Article富山大学・富医薬博甲第407号・川高 正聖・2023/03/23 公表論文 Kawataka M, Ouhara K, Kobayashi E, Shinoda K, Tobe K, Fujimori R, Mizuno N, Sugiyama E, Ozawa T, Kishi H. N-glycan in the monoclonal ACPA, CCP-Ab1 the variable region promotes the exacerbation of experimental arthritis. Rheumatology (Oxford). 2023 Mar 21:kead130. doi: 10.1093/rheumatology/kead130. Epub ahead of print. PMID: 36944270

    Cap analysis of gene expression (CAGE) 法を用いたnestin-induced Ikk2 deficientマウスにおける皮膚炎の分子病態解析

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    富山大学博士(医学)Article富山大学・富医薬博甲第419号・吉田 聡・2023/03/23 公表論

    GSTA4 governs melanoma cell resistance to anti tumor immunity

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    富山大学博士(薬科学)Article富山大学・富医薬博甲第422号・Ucche Sisca・2023/03/23 公表論文 1.Mojic M, Shitaoka K, Ohshima C, Ucche S, Lyu F, Hamana H, Tahara H, Kishi H, Hayakawa Y. NKG2D defines tumor-reacting effector CD8+ T cells within tumor microenvironment. Cancer Sci. 2021 Sep;112(9):3484-3490. doi: 10.1111/cas.15050. Epub 2021 Jul 28. PMID: 34187084; PMCID: PMC8409295. 2.Ucche S, Yokoyama S, Mojic M, Oki K, Ohshima C, Tsuihiji H, Takasaki I, Tahara H, Hayakawa Y. GSTA4 Governs Melanoma Immune Resistance and Metastasis. Mol Cancer Res. 2023 Jan 3;21(1):76-85. doi: 10.1158/1541-7786.MCR-22-0369. PMID: 36162957

    アミロイドβ の毒性配座理論に基づいたアルツハイマー病の病態解明に関する研究

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    富山大学博士(薬学)Article富山大学・富医薬博甲第428号・牧 俊人・2023/03/23 公表論文 1.Maki T, Sawahata M, Akutsu I, Amaike S, Hiramatsu G, Uta D, Izuo N, Shimizu T, Irie K, Kume T. APP Knock-In Mice Produce E22P-Aβ Exhibiting an Alzheimer's Disease-like Phenotype with Dysregulation of Hypoxia-Inducible Factor Expression. Int J Mol Sci. 2022 Oct 31;23(21):13259. doi: 10.3390/ijms232113259. PMID: 36362046; PMCID: PMC9654501. 2.Maki T, Sawahata M, Uta D, Irie K, Kume T. Chronic Treatment with Aβ42 with a Toxic Conformer and LPS Induces Inflammatory Responses in BV-2 Microglia with Dysregulation of Hypoxia-Inducible Factor Expression. Biol Pharm Bull. 2023;46(2):359-363. doi: 10.1248/bpb.b22-00855. PMID: 36724966

    A hybrid heuristic algorithm for solving the maximally diverse grouping problem

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    富山大学博士(工学)Article富山大学・富理工博甲第215号・楊笑・2023/3/23202

    The Research of Evolutionary Computation in Medical and Engineering Applications

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    富山大学博士(工学)Article富山大学・富理工博甲第216号・雷振宇・2023/3/23202

    食道扁平上皮癌におけるB4GALNT4遺伝子の発現と悪性度との関連

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    富山大学博士(医学)Article富山大学・富医薬博甲第411号・馬場 逸人・2023/03/23 公表論文 Baba H, Kanda M, Sato Y, Sawaki K, Shimizu D, Koike M, Motoyama S, Kodera Y, Fujii T. Expression and Malignant Potential of B4GALNT4 in Esophageal Squamous Cell Carcinoma. Ann Surg Oncol. 2020 Sep;27(9):3247-3256. doi: 10.1245/s10434-020-08431-8. Epub 2020 Apr 6. PMID: 32253672

    Innate immune responses against oral squamous carcinoma in an orthotopic murine model

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    富山大学博士(医学)Article富山大学・富医薬博甲第417号・Muhammad Irfan Rasul・2023/03/23・★論文非公開

    Dual engineering of olivetolic acid cyclase and tetraketide synthase for the formation of longer alkyl-chain olivetolic acid analogs and their antibacterial activities

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    富山大学博士(薬科学)Article富山大学・富医薬博甲第426号・LEE YUAN-E・2023/03/23 公表論文 1.Lee YE, Nakashima Y, Kodama T, Chen X, Morita H. Dual Engineering of Olivetolic Acid Cyclase and Tetraketide Synthase to Generate Longer Alkyl-Chain Olivetolic Acid Analogs. Org Lett. 2022 Jan 14;24(1):410-414. doi: 10.1021/acs.orglett.1c04089. Epub 2021 Dec 23. PMID: 34939812. 2.Lee YE, Kodama T, Morita H. Novel insights into the antibacterial activities of cannabinoid biosynthetic intermediate, olivetolic acid, and its alkyl-chain derivatives. J Nat Med. 2023 Mar;77(2):298-305. doi: 10.1007/s11418-022-01672-9. Epub 2022 Dec 26. PMID: 36572832; PMCID: PMC9792157

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