The Bioscan
Not a member yet
3512 research outputs found
Sort by
Machine Learning Framework for Optimization the Process Structure Property Chain in Material Engineering
Full text linkEnhancing the process-structure-property (PSP) loop plays an important role in the field of materials engineering for creating materials with specific characteristics which enhances manufacturing process efficiency. Standard approaches towards developing materials primarily depend according to experimentation evaluation and error, which might be economical & time-saving. Systematically building predictive models for complicated material networks merged with Machine Learning (ML) has shown significant potential in automating and speeding up the improvement in material operations and features with the rise of data-driven innovations. The goal of this study is to construct a model for machine learning designed to enhance material engineering's Process-Structure Property interactions. Different machine learning approaches such as reinforcement learning, deep learning & supervised learning are implemented in the technique to simulate the PSP loop. The models are trained using an enormous array comprising microstructural attributes, process parameters and properties of the material. The architecture integrates data extraction, data preparation & model evaluation protocols to ensure accurate predictions. Material qualities for polymers, metals & ceramics were accurately anticipated using an ML-based optimization methodology. It required quite less time and resources to produce materials compared with earlier strategies. Additionally, the structure proposed appropriate conditions for processing by increasing the material's durability as well as decreasing flaws. The use of machine learning may transform material creation and manufacturing by adapting high-performance developing materials faster and inexpensive.
KeywordsMachine Learning, Material engineering, PSP loop, Data-driven innovations, Reinforcement learning, deep learning and supervised learning
Studies on Foliar Feeding of Plant Growth Regulators and Micronutrients on fruiting attributes of Ber (Ziziphus mauritiana Lamk) fruits cv. Gola
Full text linkThe present study was conducted on 6-year-old Ber (Ziziphus mauritiana Lamk.) plants grown under sodic soil conditions at the Production Processing of Fruits and User Waste Land, Akma, under the Department of Fruit Science, College of Horticulture & forestry, of Acharya Narendra Deva University of Agriculture and Technology, Kumarganj, Ayodhya, (U.P.) during 2023- 24 and 2024-25. The objective of the investigation was to evaluate the impact of foliar application of plant growth regulators and micronutrients on fruiting character of Ber cv. Gola fruits. The experiment was laid out in a RBD (Randomized Block Design) and data were collected on key preharvest parameters including Fruit setting time, Fruit setting (%), Fruit drop (%) and Fruit retention (%). Among the treatments, T12 (GA3 20 ppm + NAA 30 ppm + ZnSO4 0.5% + Borax 0.5%) consistently resulted in the minimize Fruit setting time, increased the Fruit setting (%), least the Fruit drop (%) and higher the Fruit retention (%) during both the years and pooled mean as compared to control.
KeywordsBer, Fruit setting time, Fruit setting, Fruit drop and Fruit retentio
Comparative in Vitro Evaluation of Cardioprotective, Antioxidant, Anti-Inflammatory, and Anti-Apoptotic Activities of Commercial Herbal Cocktail Supplements
Full text linkCardiovascular diseases (CVDs) are the most common causes of death all over the world and this requires the constant investigation of preventive and curative measures. The worldwide prevalence of CVDs, which are stimulated by such factors as oxidative stress, inflammation, and cardiac cell death through apoptosis, has prompted interest in complementary and alternative medicine. The potentials of herbal medicines due to their historical background and multi-target characteristics present an opportunity. These include commercially available herbal cocktail supplements that are a mixture of a few allegedly cardioprotective herbs such as Hawthorn, Garlic and Turmeric, which have received considerable consumer popularity. The effectiveness of these complex mixtures is, however, not always scientifically proven, and there is urgent need to compare them to support the claims of the manufacturer. This study was aimed at carrying out a comparative in vitro assessment of the cardioprotective ability of three commercially prepared brands of herbal cocktail mixtures (named Brand A, B, and C). The approach was multi-faceted in nature with the phytochemical analysis commencing with determining the total phenolic (TPC) and flavonoid (TFC) content through aqueous extracts. This was done with a battery of important assays to measure in vitro antioxidant ability (DPPH, FRAP, ABTS), anti-inflammatory ability through TNF-a and IL-6 inhibition amid LPS-instigated macrophages model, and direct cardioprotective/anti-apoptotic impact on H2O2-induced oxidative stress cardio myoblast cells of the H9c2 rat. The key findings in the summary showed that there was a strong pecking order among the brands. Brand A displayed better performance, containing the highest TPC and TFC, the strongest antioxidant activity (lowest IC50 in DPPH assay), the strongest inhibition of the pro-inflammatory cytokines, and the strongest ability to protect the H2O2-induced cytotoxicity and pro-inflammatory ability of H2O2 on H9c2 cells. Brand B was moderately active in all assays whereas Brand C always produced the most weak effects. The phytochemical content and the observed biological activities were shown by a strong positive correlation. The key finding is that the formulation of Brand A has the most extensive in vitro cardioprotective profile, which can probably be explained by the more diverse phytochemical profile. This research has a far-reaching implication since it implies that there is a high degree of variability in the efficacy of commercial herbal products and it forms a scientific foundation allowing the consumer and the health care practitioner to select evidence-based formulations. It highlights the need to ensure that there is standardized quality control and strict scientific validation of the nutraceutical industry.
KeywordsLumbar spine; Vertebral morphometry; CT scan; Age variation; Spinal biomechanics; Surgical plannin
EFFECT OF PLANT GROWTH REGULATORS AND MICRONUTRIENTS ON YIELD ATTRIBUTES OF GUAVA (PSIDIUM GUAJAVA L.) CV. L-49
Full text linkThe present investigation entitled “Studies on effect of foliar feeding of micronutrients and plant growth regulators on fruiting behaviour, yield, quality and storability of Guava (Psidium guajava L.) fruits cv. L-49” was carried out during the year 2023-24 and 2024-2025 at Main Experiment Station, Department of Horticulture, ANDUAT, Kumarganj, Ayodhya, Uttar Pradesh, India. The treatments comprised of the spraying of different PGRs and micronutrients to study the yield attributes of guava fruits cultivar L-49. The experiment was conducted in randomized block design (RBD) with eleven treatments and three replications. The experiment consisted of eleven treatments including T1 (Control), T2 (ZnSO4 0.5%), T3 (Borax 0.5 %), T4 (NAA 40 ppm), T5 (GA3 40 ppm), T6 (ZnSO4 @ 0.5 % + Borax @ 0.5%), T7 (ZnSO4 0.5% + NAA 40 ppm) T8 (ZnSO4 0.5% + GA3 40 ppm), T9 (Borax 0.5% + NAA 40 ppm) T10 (Borax 0.5% + GA3 40 ppm) T11 (GA3 40 ppm + NAA 40 ppm) Were used for this study. The maximum fruit weight (217.05 g), maximum fruit length (9.35 cm), maximum fruit Width (6.15 cm), maximum fruit volume (196.16 cc), maximum fruit specific gravity (1.19) and highest fruit yield per plant (45.64 kg) were observed with the foliar application of T11 (GA₃ 40 ppm + NAA 40 ppm) under the agroclimatic condition of Eastern Uttar Pradesh of India.
KeywordsGuava, ZnSO4, NAA, Yield, Specific, Gravity
 
In-Vitro Antiproliferative Analysis of Aqueous Leaf Extract from Cardiospermum Halicacabum in Human Hepatocellular Carcinoma Cell Line
Full text linkBackground: Cancer is one of the multi-factorial, multi-faceted, and multi- mechanistic diseases requiring a multi-dimensional approach for its treatment, control and prevention. Many anticancer drugs in clinical use today are derived from natural sources. Cardiospermum halicacabum (C. halicacabum). is a herbaceous plant, extensively dispersed in tropical and subtropical areas of the world. The present study was designed to determine the anti proliferative activity of C. halicacabum aqueous leaf extract on human hepatocellular carcinoma (HepG-2) cells.Method: The leaves of C. halicacabum were extracted with ethanol using soxhlet apparatus. The anti-proliferative activity of C. halicacabum was evaluated by 3-(4,5- dimethylthiazol-2-yl)-2,5-diphenyl-tetrazolium bromide, a yellow tetrazole (MTT) assay and their cell morphological changes was assessed by phase contrast microscope.Results: Our present study showed the anti proliferative activity of Cardiospermum halicacabum at different concentration (25 μg/mL, 50μg/mL,75 μg/mL, 200 μg/mL and 300 μg/mL). The inhibitory concentration (IC-50) value of aqueous extract of Cardiospermum halicacabum was found to be 50 μǥ/ml which is considered to be effective dose. We observed significant morphological changes in Cardiospermum halicacabum treated cells.Conclusion: The aqueous extract of C. halicacabum has confirmed hopeful antiproliferative activity against human hepatocellular carcinoma (HepG-2) cells. In further investigations, to assess its isolates of pure bio active compounds and find out the effectiveness of the C. halicacabum to serve as natural chemotherapeutic agent
Comparative Evaluation of Physical Properties of Conventional Glass Ionomer Cement with Different Additives: An In- vitro Study
Full text linkAim: This study aimed to evaluate and compare the Physical properties of Type IX Glass ionomer cement (GIC) incorporated with 2% chlorhexidine (CHX) and 2% cetrimide.Settings and Design: An in-vitro comparative studyMaterial and Methods: The study comprised six test groups - Group 1 (Conventional GIC), Group 2 (GIC + 2% CHX), and Group 3 (GIC + 2% cetrimide). Each group contained 15 samples, which were evaluated for microleakage using dye penetration test. Class I cavity was prepared in all the samples and were restored with experimental GICs. CHX and cetrimide in powder form were added to conventional Type IX GIC at 2% W/W ratio. Thermocycling was done and dye penetration test was performed. Samples were sectioned and were evaluated for microleakage under stereomicroscope. Group 4 (Conventional GIC), Group 5 (GIC + 2% CHX), and Group 6 (GIC + 2% cetrimide) were evaluated for Compressive strength using universal testing machine. Kruskal–Wallis test complemented by Tukey’s post-hoc test and intragroup comparison was made by Student’s paired t-test for the comparative analysis of both microleakage and evaluation of compressive strength between the three experimental type IX GICs.Result: Group I showed least microleakage, Group 4 showed highest mean compressive strength.Conclusion: The present study demonstrated that experimental GICs containing CHX and cetrimide, increased the microleakage and decreased the compressive strength of the parent material
EFFECTIVE METHODS OF USING DIGITAL APPS LIKE A "PEN PALS" IN TEACHING AND LEARNING ESP AMONG ADULT LEARNERS IN THE WORLD
Full text linkThis article aims to provide an in-depth study of the effective use of digital applications such as "pen pals" in the teaching and learning of ESP (English for Specific Purposes) among adult students worldwide. ESP education, unlike traditional English language learning, is focused on developing students' professional needs and language skills in specific areas, and the use of digital applications allows for more interactive, effective and contextual language learning.The article analyzes in detail the main opportunities, advantages and limitations of applications such as "pen pals" in ESP teaching. Through these applications, students develop language skills through written and oral communication, improve intercultural communication and perform tasks tailored to their professional needs. In particular, it creates an opportunity to increase educational efficiency through specially adapted materials and tasks for students in various professional fields (for example, medicine, business, service).Through "Pen Pals" applications, students have the opportunity to use the language in real life, which accelerates their language acquisition process. Although applications increase student motivation, it is shown that there are some technological and cultural barriers. It is analyzed that special tasks in medicine, business, tourism and other fields can be effectively presented through applications. It is emphasized that integration with new technologies such as artificial intelligence, virtual reality (VR) will serve the further development of ESP education.This article is an important guide for ESP teachers and students, which will help to improve the quality of ESP education and adapt it to the needs of students using "Pen Pals" applications. The article offers extensive recommendations for implementing the capabilities of digital applications and educational technologies in practice
Pectinase immobilization on modified glass beads through salinization and its application in juice purification as a commercial activity
Full text linkThe Pectinase enzyme was immobilized on glass beads in the current work using covalent coupling. Glass beads were utilized;they were purchased from scientific stationary. Covalent coupling rendered pectinase immobile. Using pectinase - loaded glassbeads, different parameters were tuned and comparative studies were conducted following the immobilization procedure formore research. To further show that the support bead's enzyme was immobilized, FTIR & SEM analyses were conducted.Pectinase from it was used to purify fruit juice, specifically pineapple, watermelon, and sugarcane juice. Furthermore, becausethe immobilized enzyme can be reused in its whole, this study presents a novel development on the environmentally beneficialeffects of immobilized enzymes
Urbanization and Its Environmental Impact: Challenges and Mitigation Strategies
Full text linkThis means that the transformation of people from the rural structure to the urban, has been a very regular feature of modern society. As it contributes to economic growth and provides better standards of living the environment faces large problems. Urbanization normally leads to loss of habitat, pollution, resource depletion and, emission of greenhouse gases. It adds to climate change, hostile health conditions and the depletion of ecosystems all around the world. Some of the environmental effects of urbanization include; deforestation, which leads to elimination of natural ecosystems, emissions of gaseous and liquid wastes, overuse of resources and finally poor disposal of wastes. Cities are the primary hotspots of CO2 emission which is contributing to both global warming and worsening many other health challenges within the society, such as respiratory diseases. Third, the conversion of land for urban development is also a problem because it decreases access to water, pollutes it, and lowers the amount of plant and animals that can live in a region. Thus, measures against these negative impacts need to be applied as an offset. Sustainable urban planning which is aimed at practical and conceptual ways of implementing compact city designs, green infrastructure and preventing the phenomenon of the urban sprawl can lessen the loss space for habitation and decrease the levels of contamination. The figures show that incorporating renewable energy systems, optimizing the transportation system for a large number of people, and enhancing energy efficient buildings could minimize carbon emissions. Still, on the environmental impact, efficient disposal of wastes, water efficiency and any infrastructural development must be friendly to climate change. When cities incorporate these measures they are effectively moved towards more sustainable communities, whilst simultaneously promoting economic growth and development and maintaining sustainability of resources as well as stability of ecosystems. This paper holds the view that fruitful practices of urban management if backed by policies and involvement from the society can play a major role in minimizing the so pejorative effects of urbanization
Effect of Foot Reflexology on sleep quality among Autistic children in selected special schools
Full text linkA study was conduced on autistic individuals who commonly face challenges with sleep due to difficulties in relaxation & irregular melatonin levels, impacting the child & their families. The feet reflexology has demonstrated benefits in addressing sleep problems, this study aimed to assess the effect of feet reflexology on sleep quality among autistic children. A quantitative research approach with a quasi-experimental pretest-posttest control group design was used, convened sampling was used for the study. The study findings reveled foot reflexology intervention led a significant improvement in sleep quality in the experimental group, with notable decrease in moderate sleep problems (P<0.0001) thereby the study suggest the effectiveness of foot reflexology