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ANALYSIS OF SOME RESEARCH ON THE DEVELOPMENT OF COGNITIVE ACTIVITY OF CHILDREN WITH SPECIAL EDUCATION NEEDS
Get PDFThe goal defines the expected outcome and outlines the directions for the activities of students with intellectual disabilities and oligophrenopedagogues. Along with the approaches to teaching, the organizational and content structure of the model reflects the content of special corrective education and the results of learning and cognitive activities
EMERGING THREAT OF COVID-19 ASSOCIATED MUCORMYCOSIS IN INDIA: A COMPREHENSIVE REVIEW
Get PDFMucormycosis, commonly referred to as “black fungus,” has emerged as a significant secondary infection during the
COVID-19 pandemic, particularly in India. This opportunistic fungal disease, though non-communicable, spreads through
inhalation of spores that are omnipresent in the environment. Patients with uncontrolled diabetes, prolonged corticosteroid
therapy, malignancies, or immunosuppression are at the highest risk. The infection manifests with symptoms such as
headache, nasal congestion, facial swelling, eye pain, and partial vision loss. If not diagnosed and treated early, the disease
can rapidly progress, leading to high mortality rates. This review explores the epidemiology, risk factors, clinical
manifestations, and treatment approaches of mucormycosis in the Indian context, while emphasizing the urgent need for
early detection, judicious use of steroids, and improved awareness among healthcare workers and the public
Serum Lipid Profile Variation with Body Mass Index (BMI) in Diabetic and Non-Diabetic Mellitus: A Tertiary Centre Study in Puducherry
Get PDFIntroduction:Around 77 million individuals >18 years are experiencing diabetes (type 2) in India. Obesity and dyslipidemia have shared pathophysiology linked “insulin resistance”. Only very limited research works are available on diabetes with its relation to BMI and dyslipidemia. Hence, this study was planned to identify the correlation between the lipid profile and different body mass index categories among diabetes mellitus in Tertiary Care Centre.Materials and methods:This hospital based cross sectional study was done among 194 patients. Blood samples were collected for FBS, PPBS, and Serum Lipid Profile. Results were collected and entered in Microsoft Excel sheet then analysis was done using SPSS version 23.0.Results:Majority of patients 79 (40.8%) were in the age group of 40-60 years. Out of 194 patients 112(57.7%) of them are diabetic. About 54 (27.8%) patients are overweight and 48 (24.7%) are obese. It reveals that there is a significant difference in the lipid profile among diabetic and non-diabetic patients.Conclusion:This study reveals that higher serum levels of total cholesterol, triglycerides, low density lipoprotein, very low-density lipoprotein, and low level of HDL was noted among diabetes patient compared to non-diabetic patients. The chances of dyslipidemia increase in patients with type 2 diabetes with high BMI in our study
COMPREHENSIVE PAIN MANAGEMENT PHARMACOTHERAPY: A MULTIDISCIPLINARY STRATEGIES AND QUALITY ASSURANCE FOR ENHANCED PATIENT-CENTERED OUTCOME
Get PDFPain management is a critical aspect of healthcare in diseased patients, involving the alleviation of both acute and chronic pain through a multidisciplinary approach. Acute pain can often be resolved with direct pharmacological interventions, while chronic pain requires more complex treatment and coordinated efforts. Multidisciplinary teams typically include medical professionals, pharmacists, psychotherapists, and rehabilitation specialists and other healthcare professionals in the setup of the organization. Pain can persist due to ongoing pathology, unresolved trauma, or unidentified causes, necessitating varied treatment strategies such as administration of analgesics, antidepressants, anticonvulsants, physical therapy, and psychological interventions. Effective pain management mainly relies on accurate pain assessment, the chronic pain assessment and the use of quality improvement programs. The Joint Commission for Accreditation of Healthcare Organizations (JCAHO) recognized pain management as critical quality indicator in 1999, incorporating pharmacotherapy as the fifth vital sign and encouraging institutional accountability for the management of pain. Guidelines are developed by agencies such as, the Agency for Healthcare Policy and Research emphasize patient education, prompt pain assessment, and consistent documentation of treatment effectiveness. Developing quality assurance programme for the management of pain and pharmacotherapy by administering drugs of opioids, NSAIDs and other non-opioid medications. Multidisciplinary collaboration to establish various policy guidelines for quality assurance pain management establish policies, train staff, and evaluate program effectiveness.The Case studies highlight the diversity of pain management which needs across patient populations, from the postoperative care to chronic conditions. These cases which demonstrates the necessity of tailored approaches, particularly for managing pain in the elderly patients or those with complex medical conditions. A comprehensive, bio psychosocial rehabilitation approach is emphasized, integrating medical, psychological, and physical therapies to improve patient outcomes and quality of life
EFFECT OF POST SHOOTING BUNCH FEEDING OF NUTRIENTS ON YIELD AND QUALITY OF BANANA (Musa spp.) CV. NEY POOVAN (AB)
Get PDFBanana (Musa spp.) is a climatic and delicious fruit, which is nutritionally superior and economically important for local and export markets in world trade and plays a key role in the economy of developing countries. The present investigation was carried out in Department of Horticulture, Faculty of Agriculture, Annamalai University, Annamalai Nagar, Tamil Nadu, and India during the period 2022 - 2023 to assess the effect of denavelling and bunch feeding treatments on yield and quality of banana (Musa spp.) cv. Ney Poovan (AB). The experiment was laid out in a Randomized Block Design with eleven treatments and three replications. The treatment consisted with fresh cow dung slurry, vermicompost, urea, ammonium sulphate and sulphate of potash which were applied with different treatment combinations along with denavelling and bunch feeding viz., T1 - Fresh cow dung 500 ml + Urea 7.5 g, T2 – Fresh cow dung 500 ml + Sulphate of potash 7.5 g, T3 – Fresh cow dung 500 ml + Ammonium sulphate 7.5 g ,T4 - Vermicompost 500 ml + Urea 7.5 g, T5– Vermicompost 500 ml + Sulphate of potash 7.5 g , T6 – Vermicompost 500 ml + Ammonium sulphate 7.5 g, T7 - Fresh cow dung 500 ml + Urea 7.5g + Sulphate of potash 7.5g ,T8 - Fresh Cowdung 500 ml + Urea 7.5 g + Ammonium sulphate 7.5 g ,T9 – Vermicompost 500 ml + Urea 7.5g + Sulphate of potash 7.5 g , T10 – Vermicompost 500 ml + Urea 7.5 g + Ammonium sulphate 7.5 g and T11 - Denavelling alone (Control). The result revealed that the treatment T7 - fresh cow dung slurry 500 ml with Urea + sulphate of potash each at 7.5 g registered maximum bunch weight (13.96 kg), number of hands per bunch (11.16 nos.), number of fingers per bunch (155.93 nos.), TSS ( 26.73 %), acidity ( 0.18 %), ascorbic acid ( 11.27 mg 100g-1 ) and total sugars ( 20.19 %). The treatment T11(control) was the most ineffective of all the treatments regarding all the yield and quality parameters of banana (Musa spp.) cv. Ney Poovan (AB)
Knowledge and Attitude Towards Menstrual Cup Usage Among Adolescent Girls: A Study in Gurugram, Haryana
Get PDFIntroduction: Menstrual cups are becoming increasingly popular as a sustainable and cost-effective alternative to traditional menstrual products like pads and tampons. However, awareness and acceptance of menstrual cups among adolescent girls in India remain limited. This study aims to assess the knowledge and attitude of adolescent girls towards menstrual cup usage in selected schools in Gurugram, Haryana.Aim: To assess knowledge and attitude of adolescent girls regarding menstrual cup.Methods: A cross-sectional study was conducted among 60 adolescent girls using a structured self-administered questionnaire. The data collected included demographic information, knowledge about menstrual cups, and attitudes towards their usage. Descriptive statistics were used to analyze the data, and associations between demographic factors and knowledge were explored using Chi-square tests.Results: The study found that 61.7% of adolescent girls had an average level of knowledge about menstrual cups, while only 5% demonstrated high knowledge. The majority (51.66%) of respondents indicated they would never prefer using a menstrual cup, and 36.66% were skeptical about the economic benefits of menstrual cups. Significant associations were found between knowledge levels and area of residence.Conclusion: Although menstrual cups are a sustainable option for menstrual hygiene, misconceptions and cultural barriers hinder their adoption among adolescent girls. Increased awareness through educational initiatives is needed to improve knowledge and positively influence attitudes towards menstrual cups
From Dorms to Dining Tables: How Social Support Influences PCOS Management in College Students
Get PDFPolycystic Ovary Syndrome (PCOS) is a multifaceted condition that affects both physiological and psychological well-being, ultimately affecting the quality of life. This study aims to explore the importance of family support in the management of socio-emotional symptoms of PCOS in college students, particularly by comparing the experiences of students living with family and those who live independently in and around the college campus.The Polycystic Ovary Syndrome Questionnaire (PCOSQ) provided quantitative data for this mixed-methods study, while in-depth interviews provided qualitative insights. Emotional health, body hair, weight, infertility, and irregular menstruation were all evaluated by the PCOSQ. 34 college students with PCOS were included in the sample. 10 participants also participated in semi-structured interviews, which uncovered themes like the relevance of peer and community connections in lowering emotional isolation, the usefulness of family support, and challenges in independently managing PCOS-related stress. When taken as a whole, the results provide a thorough picture of young adult PCOS.The results revealed noteworthy findings where students who lived with family members reported significantly higher quality of life scores. Participants living with family underscored the value of consistent shared responsibility for health management and highlighted access to nutritious home-cooked meals, which positively impacted their physiological symptoms. In contrast, those residing independently appreciated their autonomy and, while facing challenges in practical support, reported receiving greater emotional support from friends and dorm mates than from family. The integration of quantitative and qualitative data provided a nuanced understanding of how familial social support affects the management of PCOS.These findings highlight the profound impact on how important social support, particularly from family, is in helping college students manage PCOS. To improve mental health and general quality of life, future initiatives should concentrate on family-centered interventions, peer support networks, and focused resources for independent learners
AYURVEDIC MANAGEMENT OF ASTHI-MAJJAGATA VATA W.R.T. ANKYLOSING SPONDYLITIS THROUGH PANCHATIKTA KSHEERA BASTI-A CASE REPORT
Get PDFAnkylosing spondylitis(AS) is a chronic inflammatory disease of the spine that often leads to vertebral fusion limiting movement, causing stiffness of spine and a forward stooped posture. In Ayurveda, we can co-relate with asthi-majja gata vata whereby similar symptoms of AS are found that are asthi-parva bheda, sandhi shula, mamsa bala kshaya1, santata ruja2 sandhi. Clinical studies have shown the importance of Ayurveda and Panchakarma in the management of AS. In this case study, a female patient aged 40 years age diagnosed with AS 2 years back was presenting typical symptoms of lumbar AS such as chronic low back pain, stiffness, difficulty in walking,etc. She was treated with panchatikta ksheera basti for 16 days alongside oral medications . Main assessment criteria before and after the intervention was BASDAI(Bath Ankylosing Spondylitis Disease Activity Index) scale founded by Calin et al., Bath, 1994, Range of motion of the lumbar spine and VAS(Visual Analog Scale). Patient showed significant relief in lumbosacral pain, reduced intensity, tenderness and duration of morning stiffness, reduced levels of ESR and CRP. Thus, this case supports the prominent role of Ayurveda in the management of AS through Panchakarma
EFFECTIVENESS OF PGR FOR IN VITRO CLONAL PROPAGATION OF LINDERNIA DUBIA (L.) PENNELL
Get PDFThe study focused on standardizing the in vitro organogenesis process for Lindernia dubia (L.) Pennell, a less-concerned emergent plant of the Linderniaceae family, utilizing a micropropagation technique in hormonal MS medium. Two concentrations of MS medium were tested: half-strength and full-strength, with the half-strength medium showing superior results in regeneration. Various concentrations of BAP, KIN, and GA3 were employed for shoot induction, while NAA and IAA were used for root induction. After a month post-inoculation, developed shootlets were evaluated, and statistical analyses, including ANOVA and Tukey's Multiple Comparative Analysis, were performed. Regeneration rates fluctuated from 70% to 100%, with half-strength medium outperforming full-strength in all parameters. The peak performance was noted with 8 μM BAP, yielding 11.9 cm shoot lengths and 16.2 roots averaging 10.5 cm in length in the NAA rooting medium. The full-strength medium averaged 46 shoots and 5.7 roots. In combinations of auxins and cytokinins, the 4+2 μM BAP + KIN combination produced 64.9 shoots, while KIN + GA3 yielded 63.9 shoots at 8+4 μM. Auxin-rich media (NAA + IAA) facilitated root regeneration across all combinations, recording a maximum of 2.4 roots with an average length of 1.2 cm in the BAP + KIN combination. The conclusion drawn emphasizes BAP and NAA as optimal hormones for regenerating L. dubia in half-strength medium, with BAP + KIN and KIN + GA3 being effective combinations. This established micropropagation procedure aims to enhance the population of this plant to support sustainable conservation and provide essential raw materials for future medicinal research benefiting society.
 
Serum Hormone Profiles in freshwater Catfish Clarias batrachus Exposed to Lambda-Cyhalothrin
Get PDFHormone control in aquatic creatures is disrupted by synthetic pesticides, particularly endocrine disruptors like pyrethroids. These substances interfere with cellular uptake by attaching to the receptors of hormones or plasma transport proteins, imitating or blocking hormones. Fish thyroid hormones, which are essential for metabolic rate and stress-induced glucose mobilization, are especially impacted. Organophosphates and organochlorides hinder reproduction by inhibiting pituitary gonadotropin release and gonadal development. Pyrethroids, like lambda-cyhalothrin, are known to change the structure of the gonads and hormone-related processes. The purpose of this study is to better understand how Lambda-cyhalothrin affects freshwater catfish Clarias batrachus's serum hormone levels and how it contributes to endocrine disruption and reproductive dysfunction. The results could help address more general ecological concerns about pesticide pollution in aquatic ecosystems by exposing hormonal abnormalities and gonad structural alterations. Serum hormone levels were assayed using standard biochemical methods. Using radioimmunoassay, plasma triiodothyronine (T3) and thyroxine (T4) were evaluated. Serum hormone levels in Clarias batrachus significantly decreased overall (P < 0.01) after exposure to sub-lethal amounts of lambda-cyhalothrin. Following exposure to the sub-lethal quantities of the pyrethroid, both groups exhibited an overall significant (P < 0.01) fluctuation in the blood cortisol levels, with T4 and estrogen (E2) levels dropping noticeably (P < 0.05). Progesterone levels were declined by 73.51% and 63.50% after 45 days in higher and lower exposure groups, respectively. These hormonal disruptions indicate endocrine interference by the pyrethroid.