IRIS - UNIRSM (Univ. degli Studi della Repubblica di San Marino)
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Dalla Costituzione alla l. n. 146/1990
No full textIl saggio ricostruisce le vicende che, a partire dall'emanazione della Carta costizionale, hanno caratterizzato la disciplina dello sciopero nei servizi pubblici essenziali, sffermandosi in particolare sulla giurisprudenza della Corte costituzionale sugli artt. 330 e 333 c.p. e sull'esperienza dell'autoregolamentazione sindacale, per approdare ai progetti di legge che hanno condotto all'emanazione della l. n. 146/1990
The effect of post-mastectomy radiation therapy on breast implants: unveiling biomaterial alterations with potential implications on capsular contracture
No full textPost-mastectomy breast reconstruction with expanders and implants is recognized as an integral part of breast cancer treatment. Its main complication is represented by capsular contracture, which leads to poor expansion, breast deformation, and pain, often requiring additional surgery. In such a scenario, the debate continues as to whether the second stage of breast reconstruction should be performed before or after post-mastectomy radiation therapy, in light of potential alterations induced by irradiation to silicone biomaterial. This work provides a novel, multi-technique approach to unveil the role of radiotherapy in biomaterial alterations, with potential involvement in capsular contracture. Following irradiation, implant shells underwent mechanical, chemical, and microstructural evaluation by means of tensile testing, Attenuated Total Reflectance Fourier Transform InfraRed spectroscopy (ATR/FTIR), Scanning Electron Microscopy (SEM), high resolution stylus profilometry, and Time of Flight Secondary Ion Mass Spectrometry (ToF-SIMS). Our findings are consistent with radiation-induced modifications of silicone that, although not detectable at the microscale, can be evidenced by more sophisticated nanoscale surface analyses. In light of these results, biomaterial irradiation cannot be ruled out as one of the possible co-factors underlying capsular contracture
Temperature analysis of the water supply system of a dairy company by means of a simulation model
No full textThis paper builds upon the study by Marchini et al. (2014, International Journal of Food Engineering, pp. 557–571) and represents the second part of a research project whose general aim was to analyse and optimize, through simulation, the water distribution system of a dairy company. In the first paper, the authors focused on finding opportunities for recycling water in the distribution system of the targeted company, i.e. a dairy company located near Parma (Italy) and manufacturing Parmigiano Reggiano cheese and butter. In this work, we go ahead by analysing the thermal properties (such as, primarily, the temperature) of the water used inside the distribution system and of that discharged. To this purpose, we add the relevant thermal equations to the MS ExcelTM simulation model developed in the first study. The resulting model is able to derive the temperature trend of water inside all the tanks of the distribution system. Situations where the temperature of the water used for rinsing is higher than the maximum allowed value of approx. 25°C are also highlighted and suggestions for improvement are proposed
Investigating the demand propagation in EOQ supply networks using a probabilistic model
No full textIn this paper, we introduce a new demand probabilistic approach, named M.DPA.eoq (Montanari Demand Probabilistic Approach in EOQ scenario), for predicting the demand seen by an upper-tier echelon (e.g., a distribution centre) of a supply network, serving several lower-tier echelons operating according to an economic order quantity (EOQ) reorder policy. The M.DPA.eoq is based on an analytic approach, by which we derive the distribution of the demand seen by the upper-tier echelon of the supply network. The approach has been designed to be very simple, so as to gain in pedagogical value. The simplicity and ease of application of this approach is confirmed by the possibility of exploiting general purpose software, such as Microsoft ExcelTM, to implement and validate it. Moreover, the M.DPA.eoq has potential to be directly exploited by practitioners, such as supply network managers, to estimate the distribution of the demand the upper-tier echelon will face under a defined network structure. Students and researchers could also benefit from such a model, given its ease of understanding and usage.
With the purpose of showing its potential usefulness in real cases, we discuss two practical implications of the M.DPA.eoq, referring to the use of its results for: (1) computing the bullwhip effect of the network; and (2) analysing the impact of each retail store on the variance of the demand seen by the upper-tier echelon
Static and Dynamic Analyses of Arbitrarily Shaped Laminated Composite Structures
No full textIt is well known that many applications in several fields of engineering cannot be solved analytically due to the complexity of the governing equations. Therefore, a particular technique is needed to solve numerically the problem under consideration. As regards the structural analyses, the most common approach is the Finite Element Method (FEM), which decomposes the domain in several subdomains and finds an approximate solution evaluating the equations in their weakened form. On the other hand, the authors have developed a different approach which solves the governing equations in their strong form using a higher order numerical scheme inside each element. The so-called collocation methods based on the distribution of points upon the physical domain is employed to discretize the partial differential system of governing equations. Since the domain decomposition in several elements characterizes both the two approach, the presented technique can be termed Strong Formulation Finite Element Method (SFEM) in order to stress the fact that it is based on the strong formulation. The SFEM expresses all its potentiality especially when an irregular domain is considered. In fact, most of the practical applications in civil, mechanical and aerospace engineering are quite hard to analyze due to the presence of irregular geometries, different kind of materials, cracks, curved boundaries and load discontinuities. Several structural applications are shown to demonstrate convergence, reliability and stability of the SFEM when it is applied to the static and dynamic analyses of arbitrarily shaped laminated composite plates, membranes and beams with geometrical and mechanical discontinuities
Salute e sicurezza sul lavoro
No full textLa voce ricostuisce, anche in chiave evolutiva, i principi fondamentali della disciplina legislativa italiana della tutela della salute e sicurezza sul lavoro, focalizzzando l'attenzione, oltre che sui principi costituzionali e sull'art. 2087 c.c., sulla direttiva europea n. 89/391/CE e sul d.lgs. n. 81/2008
A New Approach for Treating Concentrated Loads in Doubly-Curved Composite Deep Shells with Variable Radii of Curvature
No full textThe point load static problem for structural components is a classic numerical test that can be found in several finite element benchmarks throughout the literature. In finite element analysis, since the solution is found in integral form within each element, concentrated forces can be applied at every mesh node. On the contrary, collocation methods do not admit to apply concentrated forces at their collocation points, since only smooth and continuous functions can be discretized. Exploiting a mixed approach of integral and differential quadrature it is possible to treat concentrated loads using Dirac-delta function. Thus, this paper shows convergence, stability and accuracy of the present approach when applied to beams, plates and doubly-curved thin and thick shells. The GDQ method is considered, in particular the best grid point collocation is found in order to achieve the best accuracy using Dirac-delta function. In addition, an alternative approach is presented for the first time, simulating a point load using a continuous and smooth normalized Gaussian distribution
An improved method of supercharged transposed latissimus dorsi flap with the skin paddle for the management of a complicated lumbosacral defect
No full textOBJECTIVE: Treatment of nonhealing wounds of lower back often poses a powerful challenge. We present one of the first
report of treatment of a lumbosacral defect with a supercharged latissimus dorsi flap with the skin paddle.
CASE REPORT: We report a case of a 59 yearold man with myeloma of the sacral spine who underwent radiotherapy and chemotherapy and subsequently, laminectomies and placement of hardware for ongoing paresis and spine instability. Then, he developed an open wound and osteomyelitis of the spine with culture positive tuberculous granulomas. After multiple surgical debridement, he presented to our service and was treated with a single stage debridement followed by the performance of a latissimus dorsi musculocutaneous flap based on paraspinal perforators and supercharged.
RESULTS: This solution, allowed for augmentation of blood flow to the muscle with the inferior gluteal artery, provided coverage of the defect resistant to the pressure, and simplified post-operative management of the patient.
CONCLUSIONS: Alternative treatment options, including free tissue transfer, posed difficulties in finding suitable recipient vessels near the defect, in inserting the flap so as to restore its original length without compromising blood flow, and in postoperative care of the patient. Treatment of a lumbosacral defect with a supercharged latissimus dorsi flap with the skin paddle may represent a milestone procedure for complicated lower spine wounds