JOURNAL OF HEALTHCARE AND LIFE-SCIENCE RESEARCH
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КЛИНИЧЕСКАЯ ЦЕННОСТЬ КАРДИОСПЕЦИФИЧЕСКИХ БИОМАРКЕРОВ В ВЫЯВЛЕНИИ МИОКАРДИТОВ У ДЕТЕЙ С ВНЕГБРОЛЬНИЧНОЙ ПНЕВМОНИЕЙ
Get PDFВ настоящее время в кардиологии важное значение имеет определение тропонинов как биохимического маркера некроза кардиомиоцитов. Целью данной работы было определение маркеров повреждения миокарда и выявление наиболее значимых из них у детей с пневмониями. Возраст пациентов составил от 7 месяцев до 7лет. Определяли показатели тропонина I, α-ГБДГ , МВКК. Критерием исключения являлись врожденные пороки сердца (ВПС), нарушения сердечного ритма, генетические аномалии, так как у детей с хронической сердечной недостаточностью уровень тропонинов является малоизмеяемыми. Это объясняется отсутствием эпизодов острой гипоксии и гибели кардимиоцитов
БИОТИББИЁТ МУҲАНДИСЛИГИ ЙЎНАЛИШИДА ТАҲСИЛ ОЛАЁТГАН ТАЛАБАЛАРГА “БИОСИГНАЛЛАРНИ ҚАЙТА ИШЛАШ” ФАНИНИ ЎҚИТИШНИНГ АҲАМИЯТИ
Get PDFҲозирги замонавий тиббиёт, маиший ва электроника соҳаларидаги аппаратлар, қурималар ва жиҳозларни ишлаб чиқариш, лойиҳалаш ва таъмирлашда асосий эътибор талаб қилинувчи қурилмалар ва техник воситаларни бўлишлиги ва улар билан ишлаш малакаларига эга мутахассисларни тайёрлаш долзарб вазифалардан биридир. Тиббий-биологик жараёнларни ўрганиш, тадқиқ этиш, ташхис қўйиш ва таҳлил этишда ва аниқ далилларни олишда муҳим аҳамиятга эга. Биотиббиёт муҳандислиги, асбобсозлик, диагностика каби турли жабҳаларда фаолият олиб бораётган мутахассислар учун биотиббиёт сигналларини таҳлил қилиш ва ишлов бериш соҳаларини билишлари ва уларни ҳаётга тадбиқ қила олишлари шарт. Ушбу мақолада биотиббиёт муҳандислиги йўналишида таҳсил олаётган талабаларга «Биосигналларни қайта ишлаш» фанини ўқитишнинг аҳамияти ҳақидаги фикрлар ёритилган
EVALUATION OF BLOOD GLUCOSE LEVEL AND LIPID PROFILE IN HYPOTHYROIDISM PATIENTS UNDER LEVO THYROXIN THERAPY
Get PDFHypothyroidism is one of the common diseases in Iraq, so this study was designed to measure lipid profile in addition to glucose level in sixty people (47 women and 13 men) with hypothyroidism patients distributed the patients in to three areas in the province of Karbala. Based on hypothyroidism with clinical symptoms, patients were analyzed to measure the level of lipids and glucose the blood. The results showed that When compared to healthy individuals, the levels of thyroid hormones T3 and T4 were 1.47, 1.72, and l80.3, 86.5 ng/ml, respectively, while the levels of thyroid hormones Triiodothyronine T3 and Thyroxin T4 were lower and the rate of TSH was higher. whereas the TSH level was 10.08 ng/ml as opposed to the normal 1.5 ng/ml. With the exception of triglycerides, the results likewise revealed a reduced level of the body lipid profile. Compared to healthy individuals (Cho195.8 mg/dl), TG168.8 mg/dl, HDL (46.7 mg/dl), LDL (79.6 mg/dl), and VLDL (31.0 mg/dl), hypothyroidism patients had higher levels of cholesterol (185.3 mg/dl), triglycerides (183.9 mg/dl), HDL (43.7 mg/dl), LDL (82.0 mg/dl), and VLDL (34.0 mg/dl). Additionally, there was no discernible difference in the glucose levels of the sick and healthy individuals (119.5 and 118 mg/dl, respectively). The results also showed no significant relationship between the age and thyroid hormone level, as well as the lipid profile and blood glucose level among patients with hypothyroidism and healthy. The results also showed that women had more thyroid disorders than men
FEATURES OF THE COURSE OF PREGNANCY IN PATIENTS WITH CONNECTIVE TISSUE DYSPLASIA
Get PDFThe article is devoted to the problems associated with connective tissue dysplasia (CTD), predominantly undifferentiated forms of the disease (nDST). The relevance of the topic is due to the high prevalence of this pathological condition. The generalized nature of connective tissue damage with the involvement of the reproductive system in the pathological process significantly affects the course of pregnancy and Birth. Complications that may be associated with pregnancy, childbirth and the postpartum period in women with nDST and which cause a high need for surgical aids: amnio-, episio- and perineotomy, cesarean section are presented. Particular attention is paid to magnesium, which plays one of the determining roles in the complex biosynthesis of the extracellular matrix in the formation of connective tissue and in the morphofunctional state of fibroblasts. The methods used to detect connective tissue metabolism disorders (determination of the level of oxyproline and fibronectin in blood serum, pyrinx D and glucosaminoglycans in urine, etc.) are described. In view of the lack of reliable diagnostic (biochemical and genetic) criteria for nDST, special attention is paid to the need for an integrated approach to assessing the condition of patients using anamnesis data, the results of clinical, instrumental and laboratory examinations
ACUTE RESPIRATORY VIRAL INFECTIONS (ARVI) AND THE ELDERLY
Get PDFThe acute respiratory viral infections (ArVIs) are uncontrollable infections due to high transmissibility, broad spectrum of causative agents, the lack of effective antiviral drugs and vaccination against the majority of these agents (except for influenza virus). Furthermore, the problem of ArVI is of particular importance for elderly people taking into account the frequently occurring decompensation of pre-existing comorbidities due to ArVI that obscures ArVI and affects the course and outcome of the disease. The paper reports data on epidemiology, clinical features, diagnosis, and treatment of ArVI in elderly and senile patients
SURUNKALI VIRUSLI GEPATIT C KASALLILINING SAMARQAND VILOYATIDA TARQALISHI
Get PDFSurunkali jigar kasalliklari ijtimoiy ahamiyatga ega. Kasallanishning tobora keng tarqalib borishi, ishga layoqatli kishilarning xastalikdan zaxmat chekishi, nogironlikning avj olishi va o‘lim xollarining yuz berishi bilan belgilanadi
OLIY O‘QUV YURTLARIDA NOORGANIK KIMYO FANINI О‘QITISHDA MA’RUZA MASHG‘ULOTLARINI FAOL USULDA TASHKIL ETISH
Get PDFmaqolada oliy o‘quv yurtlarida noorganik kimyo fanini о‘qitishda ma’ruza mashg‘ulotlarini faol usulda tashkil etish metodikasi keltirilgan
ИЗУЧЕНИЕ ВЗАИМОСВЯЗИ СИНДРОМА ГИПОТИРЕОЗА С ДИСЛИПИДЕМИЕЙ
Get PDFГипoтиреоз и дислипидемия — двa нaибoлее распрoстраненных эндoкринных нарушения, которые тесно связаны с развитием сердечно-сосудистых заболеваний, являющихся ведущей причиной смертнoсти во всем мире. У пациентов с гипотиреoзом нарушения липидного обмена, такие как повышение уровня общего холестерина, липопротеинов низкой плoтности (ЛПНП) и триглицеридов, встречаются особенно часто. Это связано с воздействием сниженных уровней тиреоидных гормонов на процессы липидного метаболизма и усилением вoспалительных процессов в oрганизме. Современныe исследования показывают, что даже субклинический гипотиреоз (с минимальными симптомами) может приводить к изменению липидного профиля, повышая риск атеросклероза и других осложнений. Кроме того, дислипидемия, ассоциированная с гипотиреозом, рассматриваeтся как один из факторов развития нeалкогольной жирoвой болезни печени (NAFLD), что усиливает её значимость в контексте комплексной терапии метаболических нарушений. Таким образом, тема статьи отражает одну из ключевых проблем современной медицины, связанную с улучшeнием диагностики и лечения заболеваний, влияющих на качество и продолжительность жизни
ТУПРОҚШУНОСЛИКДА ЭРОЗИЯНИ КЕЛИБ ЧИҚИШ САБАБЛАРИ ВА ОҚИБАТЛАНИНИ ТУШУНТИРИШДА ЗАМОНАВИЙ ПЕДАГОГИК ТЕХНОЛОГИЯЛАРНИ ҚЎЛЛАШ
Get PDFДунёда тупроқларнинг ҳозирги ҳолатини ва уларни антропоген омиллар таъсирида ўзгаришини аниқлаш, эрозия жараёнларини олдини олиш, мелиоратив ҳолатини яхшилаш, унумдорлигини сақлаш ва ошириш каби устувор йўналишларда илмий тадқиқотлар олиб борилмоқда. антропоген омиллар таъсирида юзага келган салбий ҳолатларни аниқлаш, оқибатларини бартараф этиш, мелиоратив ҳолатини яхшилаш ҳамда унумдорлигини сақлаш ва оширишга доир тадқиқотларга алоҳида эътибор қаратилмоқда. Ҳозирги кунда Республикамизда суғориладиган ер майдонларини мелиоратив ҳолатини яхшилаш, унумдорлигини сақлаш, ошириш ва улардан самарали фойдаланиш бўйича давлат дастурлари доирасида кенг кўламли мелиорация тадбирлари ва илмий-тадқиқот ишлари олиб борилиб, муайян натижаларга эришилмоқда
THE INFLUENCE OF WORK PLACEMENT, WORK ENVIRONMENT AND LEADERSHIP STYLE ON EMPLOYEE PERFORMANCE WITH WORK DISCIPLINE AS AN INTERVENING VARIABLE AT PT TASPEN (PERSERO)
Get PDFGeneral Background: Employee performance is a crucial determinant of organizational success, particularly in human resource management within state-owned enterprises. PT TASPEN (Persero), operating in insurance and pension funds for civil servants, relies on effective job placement, a conducive work environment, and adaptive leadership to enhance employee performance.
Specific Background: Despite the implementation of structured job placements and leadership models, employee performance at PT TASPEN remains inconsistent. Work discipline has been identified as a potential factor influencing performance, yet its mediating role in the relationship between job placement, work environment, and leadership style is not well understood.
Knowledge Gap: Prior research has not comprehensively examined the interplay of job placement, work environment, leadership style, and work discipline in shaping employee performance. The extent to which work discipline mediates these relationships remains unexplored, creating a gap in human resource management strategies.
Aims: This study aims to analyze the direct and indirect effects of job placement, work environment, and leadership style on employee performance, with work discipline as an intervening variable.
Results: The findings indicate that job placement and leadership style do not significantly impact employee performance and work discipline. However, the work environment positively influences both employee performance and work discipline. Work discipline significantly enhances employee performance and serves as a mediator between work environment and performance but does not mediate job placement or leadership style effects.
Novelty: This study offers empirical insights into the mediating role of work discipline in the context of state-owned enterprises, contributing to the refinement of HRM strategies.
Implications: Organizations should prioritize improvements in the work environment and develop structured work discipline enhancement programs. Leadership models should be adapted to support a disciplined workforce and optimize employee performance outcomes