International Journal of Pharmacy & Integrated Health Sciences
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ASSOCIATION BETWEEN PSYCHOSOCIAL FACTORS AND STAGES OF ACNE: A COMMUNITY BASED EPIDEMIOLOGICAL STUDY IN LAHORE, PAKISTAN
No full textBackground: There is no published epidemiological study to assess the prevalence, risk factors and management of acne based on severity among youth of Pakistan which could be helpful in guiding clinical decisions. Objective: Thus, the study was aimed at finding an association of different psychosocial and physiological factors like emotional status, diet, and menstrual cycle affecting severity and duration of acne. Methods: In this cross sectional observational study with 1175 pupils, initially screened for acne, the data of only 510 pupils (43.4%) -categorized according to Lehmann grading scale- were collected from the University of the Punjab, Lahore and its beleaguered community. Results: Our data suggested that 32.74%, 47.45% and 19.80% participants were suffering from mild, moderate and severe acne, respectively. Stress (p=0.002), anger (p=0.000), smoking (p=0.003), overproduction of oil (p=0.028), protein supplement (p=0.05), intake of cheese (p=0.044) and duration of acne (p=0.000) were strongly associated with severity of acne. Among all, only 65.88% of patients were taking either oral (doxycycline) or topical (clindamycin gel) medications, while others failed to opt any treatment. Conclusion: Taken together, mild to moderate acne is common among pupils of Lahore. Therefore, it is inevitable that targeted educational modules should be designed for the youth affected by acne due to psychosocial and physiological reasons along with clinical and non-clinical management preference
The DRUG UTILIZATION EVALUATION OF MACROLIDES IN ENT OUTPATIENT DEPARTMENT IN TEACHING HOSPITAL PUNJAB, PAKISTAN.
No full textBackground: A major danger to the health care system is the rise in antibiotic resistance. The aim of current Study is to evaluate the comparison defined daily dose (DDD) and prescribed daily dose (PDD) of macrolide and to evaluate the prescribing pattern of the drug, either it met the standards or not. Methodology: Quantitative, retrospective study was carried out to measure the use of antibiotics specifically macrolide antibiotics in ENT outdoor department of teaching hospital Punjab, Pakistan. Study research from August 2021 to October 2021, the patient who was reported in OPD of ENT department during study period of 3 month retrospectively. Results: Total 438 prescriptions were collected and reviewed to evaluate the prescribing pattern of macrolides in outdoor patients of ENT department. Out of 438 prescriptions only in one prescription 10 antibiotics was prescribe (polypharmacy) and in 19(4.3%) prescriptions only one antibiotic is prescribed. Drug prescribed by their generic were 438(100). Encounter with antibiotics 95%. All drug were prescribed from essential drug list (EDL). Azithromycin was the most commonly prescribed drug in ENT department, followed by clarithromycin. Conclusion: Control bacterial resistance is become challenge to our health care system, major portion of our population is become resistance to majority classes of antibiotic if this practice will continue in future, it became difficult to control or treat infectious diseases. Irrational use of drugs, over prescribing of antibiotics and brand prescribing were observing during the study. Lack of knowledge and non-adherence to the prescribing indicators are the major factors that contribute towards the irrational drug prescribing that ultimately leads towards the antibiotics resistance
AN UPDATED REVIEW ON ELECTROCHEMICAL TECHNIQUES
No full textElectrochemistry is a branch which deals with the electricity production by chemical changes. This review is mainly concerned with the electrochemical methods. This technique uses the potential measurement by analyzing charges, which causes chemical changes to occur through Reactions
Prosopis cineraria Druce (Jand) – A Review of its Ethnomedicinal, Phytochemical and Pharmacological Properties: Ahmed Umer Sohaib, Atta-ur-Rehman, Roheena Sohail
No full textThe use of medicinal plants and validation of their pharmacological properties have exponentially increased since last century. Selection of solvents for making plant extracts that yield significant results has also been a subject of discussion. Prosopis cineraria commonly called Jand, Khejri, Khej has great medicinal importance due to its broad range of phytochemistry and pharmacological properties. It is native to Pakistan, India, Oman, Afghanistan and few European countries. Many different parts of this plant are used traditionally for the treatment of numerous mild to serious diseases. Stem bark, root, seeds, leaves and flowers are predominantly used for the effective treatment of multiple ailments with a range of pharmacological actions involving gastrointestinal, metabolic, spasmolytic, anti-oxidant, antitumor, anti-convulsant, anthelmintic, anti-microbial, analgesic, anti- pyretic, bronchodilator, and anti-lipidemic properties. The present review highlights only the methanolic extract of this plant that has more validated pharmacological properties as compared to ethanolic, aqueous, chloroform and petroleum ether extract
Formulation and Optimization of Aceclofenac Loaded Nanosuspension : Umair Afzal, Syed. Muhammad Aun, Muhammad khuram shahzad, Razi ullah khan, Syed Ahmad Shah, Alishba Ch
No full textBackground: The aceclofenac sodium is used as non-steroidal anti inflammatory drug (NSAID), administered through the oral route, causing numerous side effects like nausea, vomiting, dyspepsia, gastrointestinal bleeding and peptic ulcer. NSAIDs, promote the secretions of hydrochloric acid which cause severe damage to the walls of gastro intestinal tracts well as to the drug.
Objectives: Aceclofenac was added in combination with different polymers to form a uniform nano suspension.
Methodology: Three sets of formulations were prepared by using silverson mixer. The organoleptic evaluation, particle size determination, assay, in vitro drug release study and drug excipient compatibility studies were performed. The results were obtained on the basis of drug and excipients compatibility studies, scanning electron microscopy, In vitro drug release study and assay studies.
Results: In this study, the nanosuspension of aceclofenac sodium is produced, which spread on the wider surface area of GIT. Due to this reason, the decrease in accumulated concentration, the secretion of hydrochloric acid is not promoted, the chance of damage to GIT is drastically reduced, and the drug also escaped from the damage and the absorption of drug is also increased.
Conclusion: The F1 formulation showed best results as compared to other two formulations. These results were obtained due to the effect of polymers used in combination with drug and surfactant
HEPATITIS-A QUICK VIEW
No full textViral HepatitisEvery one of us has heard the word “hepatitis” and considered it a fatal disease. “Viral hepatitis” is the inflammation of the liver that is caused by a nasty family of viruses. Due to hepatitis, it is estimated that globally 1.34 million people died per year and it is also reported that about 80% of cases of liver cancer are only caused by hepatitis B and Hepatitis C together. The number of patients having this infection is amplifying each year, which is quite an alarming situation (1).
Viral Hepatitis Modes of TransmissionHAV (Hepatitis A Virus) transmitted by the contaminated water (fecal-oral route), and for HBV (Hepatitis B Virus) and HBC (Hepatitis C Virus)There are mainly four modes of transmission, these are;1. Via blood2. Through sexually contact3. Through needle sharing during drug administration and4. From an infected mother to baby.Further, health care professionals who are dealing with the patients and their sample are also at higher risk
Knowledge, attitude, perception towards COVID-19: A cross sectional study among nonprofessional population of Lahore: Syed Muhammad Ali, Mariam Basharat, Daniyal Saif , Haniya Tahir, Tayyab Tariq , Farooq Rashid
No full textBackground: On account of the COVID-19 pandemic, there is very different knowledge, attitude and perception among non professional population. We are cognizant that pandemic can becontrolled by providing proper knowledge and their satisfactory attitude and positive perception towards COVID-19.
Objective: It is aimed to investigate the knowledge, attitude and perception regarding COVID -19 among non-professional population of Lahore. Methods: A cross sectional survey was conducted in June, 2021 by validated self – dministered questionnaire. The survey instrument was tailored from a published questionnaire comprised of questions on demographics, knowledge, attitude, perception.
Results: Out of 150 random participants, 63 were employees, 43 were businessmen, 29 were daily wagers, 9 housewives. Irrespective of profession, population of Lahore has average knowledge, attitude and perception. While considering the categories we included, businessmen have better knowledge and perception while attitude is satisfactory among employees. While daily wagers showed poor knowledge, attitude and perception. Housewives also have average knowledge about this virus.
Conclusion: People with greater exposure like businessmen are well aware and up-to-dated about COVID-19. Due to limited social contact housewife had not enough knowledge about COVID-19. There is need to provide equal chances to all population to get proper knowledge and awareness about this virus so that we can control it inbetter way
Editorial of International Journal of Pharmacy and Integrated Health Sciences
No full textoai:ojs.ijpihs.pk:article/1It gives me pleasure to announce the very first edition of the ‘International Journal of pharmacy and integrated health sciences\u27, a bi-annual journal published by the Pharmacy Department of Superior University.
Only a year ago, the honorable Rector Dr. Sumaira Rehman and Chairman of the group, Prof Dr. Chaudhry Abdul Rehman along with Directors of the Research Committee ordained a team of enthusiastic researchers to venture on publishing a new journal in the field of medicine and allied sciences.
Such an edition was dire felt need of presenting the academic quality of Pharmacy Department and Research carried under the supervision of ORIC, steering it to next level; meeting both the need of market and accepted health standards of the current time. The Journal has been carefully designed to pertain to the most substantial and valid information from the field of medicine delivered at a level capable of sustaining global standards of research, quality, and communication.
The journal is designed to be published, both in hard copy and in an electronic format with the online release of abstracts and another database. Through this platform, I invite all researchers from dedicated fields of science and medicine to join hands for presenting their work under a platform that shall reach out to many
IMPACT OF PHARMACEUTICAL BIOTECHNOLOGY
No full textWe are living in an era of transformation and miracles happen each day. Biotechnology is the combination of two words “technology and biology”. The domain of Biotechnology is very wide in which cells or cellular parts, biological pathways and organisms are used to develop new innovative technologies. Novel procedures, tools and products are developing day by day, which are used in research, agriculture, industry and the health care system. Pharmaceutical Biotechnology is the application of biotechnology principles and procedures in the development of drugs. Pharmaceutical biotechnology is the quite innovative, dynamic and rapidly emerging field and driving a global alteration from illness to wellness. Since last few years, pharmaceutical biotechnology has played a key role in drug research and development, and innovatory changes have been happening in health care setups, especially in field of oncology, infectious diseases and metabolic disorders. Due to the Pharmaceutical Biotechnology, a groundbreaking transformation is occurred in the field of drug discovery. Various biotechnology techniques (i.e. cell culture, genetic modeling and immunochemistry) use in drug discovery and have also paved the way to explore new avenues of drug discovery that are beneficial to the mankind
Editorial of International Journal of Pharmacy and Integrated Health Sciences
No full textThe International Journal of Pharmacy & Integrated Health Sciences (IJPIHS) began in 2021 and its achievement is deceptive in the number of manuscripts submitted and the diversity of scientific themes comprised by the journal. We trust that IJPIHS should endure serving a wideranging concern dealing with the specialized area of Pharmaceutical and Biological Sciences. Submission of a paper to IJPIHS infers that all the corresponding and co-authors should be aware of the manuscript submission and it may not be under consideration and/or not be the part elsewhere. This journal targets to inaugurate a platform for providing research ideas on novel developing tendencies in pharmaceutical and integrated health sciences