Central Asian Journal of Medical and Natural Science
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ВЛИЯНИЕ ВОСПАЛИТЕЛЬНЫХ ПРОЦЕССОВ НА РАЗВИТИЕ ИШЕМИЧЕСКОЙ БОЛЕЗНИ СЕРДЦА
No full textВ этой статье взгляды нашей страны и иностранных ученых упомянули о лечении влияния процессов воспаления на развитие сердечно -сосудистых заболеваний
REVIEW OF STANDARD AND ADVANCED SURGICAL TREATMENTS FOR INVASIVE BLADDER CANCER
No full textAccording to the Global Cancer Observatory, in recent decades, about 400 thousand primary patients diagnosed with bladder cancer have been identified, and in 2020 the number of patients registered with bladder cancer has already reached 573.3 thousand (3% of all cancer cases). Men are much more likely to suffer from this cancer pathology and the ratio is approximately 1:9. In the overall structure of cancer incidence in 2020, breast cancer took 17th place in women and 6th place in men. This pathology caused death in 212.5 thousand patients in 2020, and the mortality rate per 100 thousand men was 3.3 cases and 0.9 cases in women. Invasive bladder cancer is a cancer that is becoming increasingly common among men. Radical cystectomy is widely used as the primary treatment for this type of tumor. In order to improve the quality of life of patients, which is no less important than the survival rate, specialists in modern practical oncology have introduced more than 46 types of urine diversion into practice in the period after such highly traumatic operations. Complications after these operations and the problem of their elimination also remain relevant
Smoking Trends Among Secondary Students in Kirkuk
No full textSmoking is a major contributor to health disparities, associated with numerous illnesses including cancer and coronary heart disease. Despite extensive research on the health consequences of smoking, there remains a gap in understanding smoking behaviors among adolescents. This study investigates smoking behaviors and related factors among secondary school students in Kirkuk City. Employing a cross-sectional design, a sample of 119 students was surveyed using simple random sampling. Results reveal a prevalence of daily smoking among adolescents, indicating a habitual pattern, alongside intermittent smoking behaviors suggesting experimentation or occasional use. These findings underscore the varied smoking patterns among adolescents and highlight the need for targeted interventions to address smoking prevalence and promote adolescent health
Patient Beliefs toward Epilepsy
No full textEpilepsy is a common chronic brain disorder that affects people of all ages, genders, races, income statuses, and geographic locations. Approximately 7.6 out of every 1,000 individuals will experience epilepsy at some belief in their life. The most significant factors contributing to this are negative beliefs about the risks associated with epilepsy and feelings of being unable to control it. Pre-experimental design, with pre-and post-tests for a single group, was the method utilized in this study. The study was conducted at the Baquba Teaching Hospital's adult neurology outpatient clinics in the Diyala Governorate of Baquba City, Iraq, that begins between (July 11th, 2023, and December 5th, 2023). A sample of 100 epileptic patients, including both genders, was chosen using convenience sampling. The Epilepsy Beliefs Scale (EBS) was employed to collect data for this study. Both descriptive and inferential statistics were used in the statistical analysis. The patient's Belief about Epilepsy has enhanced as an effect of the instructional program.Founded on these outcomes, the present research recommends using the educational program as a guide to acquire beliefs about epileps
Determination of Some Drugs in Blood Plasma Using Liquid Chromatography-MS
No full textThe accurate quantification regarding febuxostat levels in human plasma will be accomplished using a liquid chromatography - tandem mass spectrometry (LCESI-MS/MS) assay with a robust sensitivity, selectivity, and reliability. Indomethacin was used as the internal standard (IS) in the test. Using methyl tert-butyl ether as extraction solvent, the analyte as well as IS have been mined from 200μL human plasma sample using extraction procedure (liquid - liquid). A Hypurity C-18 column with particle size dimensions of 100mm x 4.6mm and a column with 5μm particle size were used in the experiment in order to perform the chromatography. Under isocratic circumstances, the chromatography has been performed. Tandem mass spectrometry, which could operate in a negative ionization reaction condition range and efficiently observe various reaction modes, has been used for the purpose of detecting the analyte and internal standard. The deprotonated precursor ions were represented by observed changes of product ions for the febuxostat and indomethacin, which have been m/z 356.10 → 312 and 315.10 → 271, respectively. This technique had demonstrated a 0.05μg/mL limit of quantitation and a 0.0025 μg/mL limit of detection. Validated linear dynamic range of febuxostat has been found to be 0.05g/mL–6g/mL. Precision, which is expressed as the coefficient of variation (% CV) within and across batches, has been determined to be ≤7.1%. It was revealed that average extraction recovery of the febuxostat at various levels of quality control has been >87%. In order to ascertain bio-equivalence of 80mg febuxostat tablet form in a group that includes 14 healthy males of origin, the current study successfully used the previously indicated methodology. The experiment was conducted under both fed and fasted circumstances. The potential for duplicating the measurements regarding study outcomes was shown by re-examining 110 incurred cases
Hemostatic Nanobiocomposite Based on the Base Cellulose Derivatives
No full textA method has been developed for producing a composite biodegradable hemostatic agent in the form of films based on sodium H carboxymethylcellulose (Na-H-CMC), oxycellulose (OC), nanocellulose (NC) and chemically bound calcium ions. The contents of the components in the hemostatic agent, in terms of dry matter, were 55% for Na-H-CMC 30% for OC, 4% for NC and 11% for calcium chloride. Biodegradable films 100 µm thick were obtained; their hemostatic time was 34 ± 2 s. Studies were carried out to determine acute and chronic toxicity and hematological and biochemical parameters of the blood of experimental animals. Based on these research results, the possibility of using hemostatic compositions in practical medicine has been established
Compare the Efficacy of Thoracic Epidural Anesthesia (TEA) with General Anesthesia (GA) in Thoracic Surgical Comparative Studies to that of Total Intravenous Anesthesia
No full textThis study aimed to compare the efficacy of thoracic epidural anesthesia (TEA) combined with general anesthesia (GA) versus total intravenous anesthesia (TIVA) in thoracic surgical procedures, focusing on factors such as shunt fraction, hypoxic pulmonary vasoconstriction, and oxygenation levels during one-lung ventilation. A total of 150 patients with ASA physical status II-III scheduled for lung resection due to pulmonary illness were randomly assigned to two groups: Group A received TIVA with propofol and fentanyl, while Group B received TEA with low-dose isoflurane and bupivacaine. Hemodynamic parameters, oxygenation levels, and shunt fractions were measured before, during, and after surgery. Results indicated that while both anesthetic methods were safe, TEA with GA better preserved arterial oxygenation levels compared to TIVA, potentially due to differences in cardiac output changes. Patients in the TEA group also experienced shorter extubation times and lower postoperative pain scores, suggesting potential benefits for patients with preexisting cardiac issues and decreased oxygenation during one-lung ventilation
The Association between Pregnant Women’s Satisfaction and Antenatal Care Service in Maysan Public Health Centers
No full textPregnancy is a very important and special event from both social and medical points of view. Maternal satisfaction with antenatal care (ANC) services has been linked to the quality of the provided services and the extent to which specific maternal needs are met This study aimed to evaluate pregnant women’s satisfaction with antenatal care services at primary health care centers in Maysan city.This study aimed to evaluate pregnant women’s satisfaction with antenatal care services at primary health care centers in Maysan city.This quantitative descriptive study was conducted from January 2d to February 19th, 2024. The sample of study included a purposeful (nonprobable) sample method and included 390 pregnant women who visited primary health care centers. The study instrument includes participants’ sociodemographic characteristics, reproductive characteristics, The Measure of patient satisfaction with the provided care, Data were collected through self-report and analyzed using the statistical package for social science, IBM version 27.The results show that the multiple regression model negatively predicts women’s satisfaction with antenatal care services at primary health care centers (p value = .006). This study conclude revealed that antenatal care services at primary health care centers negatively predict women’s satisfaction with these services
Evaluation of Insulin Levels, Insulin Resistance, and Some Biochemical Variables in Males With Complications of Uncontrolled Diabetes
No full textDiabetes complications significantly impact health, yet the relationship between insulin levels, insulin resistance, and related biochemical variables in males with uncontrolled diabetes remains underexplored. This study aimed to assess insulin, HbA1c, glucose levels, insulin resistance, and body mass index (BMI) in males with diabetes complications compared to healthy controls. Conducted from December 2023 to May 2024 in Hawija’s hospitals and clinics, the study included 70 male patients aged 40-70 with diabetes complications and 20 age-matched healthy controls. Results revealed significantly higher levels of insulin, glucose, insulin resistance, and BMI in patients with diabetes complications (P ≤ 0.01) compared to controls. The study concludes that increased insulin resistance due to elevated insulin and glucose levels contributes to severe diabetes complications, including neuropathy, retinopathy, and vascular disease
Leveraging Data-Driven Intelligence for Remote Patient Monitoring in Digital Health
No full textData-driven intelligence in digital health refers to the integration of large-scale data from diverse sources to enhance health outcomes, particularly through remote patient monitoring. Utilizing advanced digital technologies such as wearable sensors, smartphones, and remote monitoring systems, real-time health data is collected from patients and transmitted to healthcare providers. This continuous data stream allows for the application of machine learning algorithms to analyze health patterns, predict potential outcomes, and offer personalized treatment recommendations. By leveraging data analytics, healthcare providers can make informed, timely decisions that cater to the individual needs of patients. Remote monitoring enables proactive management of chronic diseases, early detection of potential health issues, and reduced hospital visits, contributing to improved patient experience. Furthermore, this approach enhances healthcare efficiency by reducing the strain on healthcare resources, enabling cost-effective care delivery, and improving access to healthcare, especially in underserved populations. The overarching goal of data-driven intelligence in digital health is to provide better health outcomes, optimize healthcare processes, and deliver more personalized and predictive care. This innovative integration of technology into healthcare represents a transformative step toward more efficient, patient-centered, and data-informed healthcare systems