Central Asian Journal of Medical and Natural Science
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ОСОБЕННОСТИ ЭХОКАРДИОГРАФИЧЕСКИХ ПОКАЗАТЕЛЕЙ У БОЛЬНЫХ ОСТРЫМ КОРОНАРНЫМ СИНДРОМОМ С СОПУТСТВУЮЩИМИ НЕЙРОВЕГЕТАТИВНЫМИ НАРУШЕНИЯМИ
No full textЕжегодно регистрируется около 520 тыс. случаев острого коронарного синдрома (ОКС), который является наиболее тяжелой формой ишемической болезни сердца (ИБС) и представляет непосредственную угрозу жизни больных. Распространенность депрессивных расстройств среди населения так же достигает высокие показатели среди населения в коморбидности с ИБС. Важно отметить тесную взаимосвязь депрессивных и тревожных расстройств: депрессия почти всегда сопровождается тревожной симптоматикой. За последние 20 лет получены данные, показывающие, что депрессия примерно в три раза чаще встречается у кардиологических больных, чем среди населения в целом, кроме того, депрессия может быть фактором риска сердечно-сосудистой смертности у пациентов с ИБС. «Порочный круг», связывающий депрессию и сердечно-сосудистые заболевания, требует большего внимания со стороны современных клиницистов. Однако до настоящего времени механизмы, лежащие в основе взаимосвязи между этими заболеваниями, остаются недостаточно изученными. В последние десятилетия при помощи эхокардиографии (ЭхоКГ) активно изучаются процессы ремоделирования сердца, возникающие в результате осложненного течения ИБС (ОКС, острый инфаркт миокарда) и воздействия экстракардиальных факторов
ДЕФИЦИТ ГОРМОНА РОСТА У ВЗРОСЛЫХ: ПРОБЛЕМЫ ДИАГНОСТИКИ И ЛЕЧЕНИЯ
No full textДефицит гормона роста (ДГР) – это состояние, когда организм взрослого человека не производит достаточное количество гормона роста, необходимого для нормального функционирования организма. Этот гормон играет ключевую роль в регуляции роста, образовании костной ткани и общем метаболизме. Несмотря на то, что дефицит гормона роста часто ассоциируется с детским развитием, он также может возникнуть у взрослых, представляя собой серьезную медицинскую проблему
PHENOTYPIC DIAGNOSIS OF LABORATORY CULTURE OF FUNGI ISOLATED FROM THE EXTERNAL EAR CANAL EXTERNAL AUDITORY CANAL CAUSING OTITIS EXTERNA
No full text69 isolates of fungi causing fungal external otitis EAC Otomycosis were obtained from patients with fungal external otitis 76.66% of the total number of 90 otological smears, 17 isolates of which belong to the genus Candida spp, 27 isolates belong to the genus Aspergillus spp, 4 co-infections of the said sexes, 5 isolates belong to the genus Alternaria, and 9 isolates belong to the genus penicillium, 6 isolates belonging to the genus Fusarium, and 5 isolates belonging to the genus Rhizopus all fungi were diagnosed by traditional methods through phenotypic examinations on a petri dish as well as the study of microscopic traits, so candida albicans and Aspergillus niger is the most visible fungus species in this study
OXIDATION OF N-ACETYL ALANINE BY CHLORAMINE-T IN PRESENCE OF HYDROCHLORIC ACID: A KINETIC AND MECHANISTIC STUDY
No full textThe purpose of this work is to examine the mechanism and kinetics of N-acetyl alanine oxidation by Chloramine-T (CAT) in a hydrochloric acid medium at temperatures between 30 and 50 degrees Celsius. First-order kinetic dependency on both the oxidant [CAT] and [H+] is indicated by the experimental results. On the other hand, there is zero-order dependence on the substrate reactant [S] and chloride ion [Cl-]. The reaction is barely impacted by the medium's ionic strength. The reaction between N-acetyl alanine and Chloramine-T shows a 1:1 stoichiometry in the acidic media. To find the activation parameters, the reaction was examined at five different temperatures, ranging from 30°C to 50°C. Spectroscopic analysis revealed that the ultimate oxidation product of N-acetyl Alanine was N-chloro acetyl Alanine
ОСНОВНЫЕ МЕРЫ ПРОФИЛАКТИКИ И БОРЬБЫ С ТУБЕРКУЛЕЗОМ СРЕДИ НАСЕЛЕНИЯ ПРИАРАЛЬЯ И ХОРЕЗМСКОЙ ОБЛАСТИ
No full textБорьба с туберкулезом в мире остается одной из важнейших задач общественного здравоохранения.Туберкулез среди населения распространен всюду. Предрасположенность к туберкулезу можно объяснить наличием факторов риска.Наиболее распространенными факторами риска являются медико-биологические инфицированность, дефекты противотуберкулезной вакцинации, наличие форм, эпидемиологические, контакт с больным туберкулезом, географические и экологические, возрастно-половые, социальные неблагоприятные жилищные условия жизни
STUDY SOME IMPORTANT BIOMARKERS IN PATIENTS WITH CHRONIC KIDNEY DISEASE
No full textThe current investigation was aimed to study some important biomarkers in patients with chronic kidney disease. Between June and October of 2023, 80 patients were recorded for CKD cases at Al-Jumhuri Hospital and Azadi Teaching Hospital. In Kirkuk, Iraq, at private laboratories, experimental work was conducted. The present study's participants had been divided up as follows: 40 healthy volunteers as control group. 80 patients with CKD as a second group. The results showed that creatinine level in patients (6.37±1.56 mg/dl) was indicated a substantial (P≤0.05) rise when compared to the normal individuals (0.95±0.17 mg/dl). Urea level in patients (154.02±25.84 mg/dl) indicated a substantial (P≤0.05) rise when compared to the normal individuals (29.17±5.32 mg/dl). The Copeptin level in patients (6.13±0.49 pmol/L) was indicated a substantial (P≤0.05) rise when compared to the normal individuals (3.04±0.58 pmol/L). B2MG level in patients (3.47±0.35 ng/ml) was indicated a substantial (P≤0.05) rise when compared to the normal individuals (2.28±0.21 ng/ml). The MDA level in patients (3.94±0.31 nmol/ml) was indicated a substantial (P≤0.05) rise when compared to the normal individuals (1.47±0.7 nmol/ml). GSH level in patients (0.2573±0.052 nmol/ml) was indicated a substantial (P≤0.05) reduce when compared to the normal individuals (0.4831±0.052 nmol/ml). Based on the current results, Copeptin, B2MG, Malondialdehyde and glutathione, in addition to urea and creatine, can be considered important criteria for diagnosing chronic renal failure
ИММУНО ГЕНЕТИЧЕСКИЕ АСПЕКТЫ ДИАГНОСТИКИ, ПОСТКОВИДНЫЙ НЕКРОЗ ГОЛОВКИ БЕДРА
No full textВ данной статье изложены мнения наших отечественных и зарубежных ученых относительно иммуногенетических аспектов диагностики, лечения постковидного некроза головки бедренной кости
Chemical Effects on the Origin of Arterial Hypertension Disease
No full textArterial hypertension, a pervasive and multifactorial cardiovascular disorder, continues to pose a significant global health challenge. This paper explores the intricate interplay between chemical exposures and the onset of arterial hypertension, shedding light on the diverse mechanisms through which various environmental and endogenous chemicals may contribute to the development and exacerbation of this disease. Emphasizing the importance of understanding chemical-induced vascular alterations, the review synthesizes current knowledge on the impact of pollutants, heavy metals, pharmaceuticals, and endocrine-disrupting chemicals on blood pressure regulation. Furthermore, it delves into the molecular pathways implicated in chemical-induced vascular dysfunction, oxidative stress, inflammation, and endothelial dysfunction. A comprehensive analysis of epidemiological studies and experimental models underscores the relevance of chemical exposures as potential risk factors for arterial hypertension. Ultimately, this review provides valuable insights into the complex relationship between chemical agents and the pathogenesis of arterial hypertension, offering a foundation for future research and preventive strategies
Designing a Mobile App for Adolescent Health as Pre-Marital Preparation to Prevent Early Stunting: A User-Centred
No full textStunting is a condition where toddlers have less length or height than their age. Premarital preparation is where men and women must prepare themselves from all physical, mental, and socio-economic aspects. This study aims to design a Mobile App for Adolescent Health as Pre-Marital Preparation to Prevent Early Stunting. This study was conducted in Posyandu (adolescent integrated service center) in Sidoarjo. A total of 22 participants were recruited through an online survey. According to several respondents who have seen the first mobile prototype, the overall UI/UX of the website already has a decent appearance and provides a good experience, in line with user expectations. The midwife interface must be added to the edit menu and the history of activities or services provided to adolescents. Teenagers say that this app fulfills all their health needs. As with most studies, this is not a perfect study, but several key questions have been studied according to the systems science methods, and some relevant results have been obtained to help solve these problems. This study takes the redesign of the user interface based on feedback from respondents after the redesign is carried out, an application ready to be used for adolescent health services created to be software usefully
Post-Pandemic Sleep Disorders: Understanding Insomnia in the Aftermath of COVID-19
No full textSleep issues after recovery have gotten a limited amount of investigation, despite the fact that the effects of COVID-19 are becoming more commonly understood. Students which had made a full recovery from COVID-19 were compared to individuals who had never been infected in order to determine the links between the between sleep interruptions and students who had recovered. In this research, both students evaluations were conducted on pupils who had recovered from COVID-19 as well as individuals who had never been infected again. The students were paired using age, gender, education and socioeconomic background. The study had a total of 110 participating students. In-between November of 2021 and March of 2022, students from the Pharmacy College and other colleges belonging to Al-Qadisiyah University were selected. A socio-demographic and clinical checklist was used together with the Pittsburgh Sleep Quality Index and the Hospital Anxiety Depression Scale in the interviews done with participants. Other measures used in this study include the Pittsburgh Sleep Quality Index and the Hospital Anxiety Depression Scale. However, fifty percent of those who recovered reported sleep problems whereas fifty percent of those that were nonrecoverable cases did not. A total of fifty-five percent (55/1110) of recovered COVID-19 students and one hundred percent (55/55) of control participants were found to have sleep disturbances, respectively. The recovered participants, with the exception of those who used medications, exhibited significantly higher levels of sleep instabilities across all domains that were measured by the Pittsburgh Sleep Quality Index questionnaire. This group of domains comprised There was a significant difference (P < 0.001) in the quality of sleep, latency, duration, efficiency, disruptions, and daytime dysfunction, as well as the overall PSQI score (P ≤ 0.001). First, it was demonstrated that students suffering from covid 19 recovered have a worse subjective sleep quality and that major depressive symptoms did not contribute significantly to sleep measure and numerous researchers have agreed on the need for further researches in order to uncover the complex relationship between Covid 19 and sleep. 2.3%, confidence interval with a 95% rate: Some typical symptoms of the sleep disorder include are measures of sleep quality and some indicators of the hyperhidrosis and abnormal pandemic waters of the covid-19. The Covid-19’s relationship to sleep difficulties is still a researchable area of concern as a possible consequence of COVID-19. This is because COVID-19 has the capacity to affect either the physical or the psychic that leads to the impairment of either psychic or physical functions