European Journal of Medical and Health Research
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Genetic Influences on Mental Health
Get PDFMental and physical health are two most crucial factor that deciding the happiness and development of each individual in the world. Physical health problem is quite obvious and easy to be recognized through advanced and modern technology. However, mental health sometimes invisible and hard to be revealed by the machines and the patients themselves. It is believed that genetic factors play a significant role in the development of various mental health conditions. Based on extensive research, scientists categorize major mental illnesses into several types, including schizophrenia, bipolar disorder, depression, and anxiety disorders. The primary causes of these mental health issues are rooted in organic, psychological, abnormal physical structures, and endogenous factors. Treatment for mental health disorders includes a range of therapies such as medication, electroconvulsive therapy (ECT), transcranial magnetic stimulation (TMS), psychotherapy, and rehabilitation. It is essential for individuals to adopt different measures such as regular exercise, maintaining a positive attitude towards life’s challenges, helping others, and following a healthy diet to escape from mental health issues. This research used a survey conducted with over 200 participants to understand more about the relationship between mental health and genetics, offering recommendations for reducing the incidence of mental health issues
Effect of Smoking on Hematological Parameters in Patients with Polycythemia and Comparing Them with Healthy People
Get PDFThe aim of this study is to Measure the red and white blood cells and platelet counts (complete blood picture). in patients with polycythemia and comparing them with healthy people(control). 90 blood samples are collected from these patients (54 smokers, 36 nonsmokers) and they are compared with 40 blood samples of healthy persons within the age range of (18-79 years). A Hematocrit (HCT) criterion of 52% is used in the study as a sickness criterion. Results of the statistical analysis show a significant increase (p<0.001) in red blood cells, compared to the control group, there was a significant rise in the number of white blood cells (p0.05) and neutrophils, monocytes, and eosinophils (p0.001), but a significant fall in the number of lymphocytes and basophils (p0.001). The platelets count did not mirror any significant variations between the patients and control groups despite the increase in platelet numbers in persons with polycythemia group that are nonsmokers and a decrease in smokers. Notes from the above results The effect of smoking on blood serum show a significant increase in red blood cells, hematocrit, white blood cells, and that this increase appears clearly in smokers and non-smokers patients
Psychological Correction of Adolescent Aggression
Get PDFAggression is any behaviour that contains a threat or causes harm to others. It is aimed at insulting or inflicting pain on another person who does not wish for such treatment. Nowadays, adolescent aggression is a global issue. During adolescence, various types of psychological traumas form, leading to the development of aggression. In adolescence, aggression can pose a serious problem, affecting the psychological well-being, social relationships, and academic performance of teenagers. The psychological correction of aggressive behaviour in adolescents is a crucial aspect of their overall development and adaptation. The modern reality forces us to take a new look at the problem of adolescent aggression in society. Aggressive behaviour today is more of a norm than an exception. Nowadays, boys and girls live in an era of rapid oppression by adults. The characteristics of aggressive behaviour are such that, by encroaching on the emotional sphere of the personality, they contribute to the aggravation of moral dissonance and the formation of stressful depressive states. A troubling symptom is the increase in the number of minors with aggressive behaviour, manifested in antisocial actions (alcoholism, vandalism, drug addiction, disorderly conduct, hooliganism, etc.)
Significance of Mineral Bioavailability in Food Containing Antinutrients, Tacca leontopetaloides L. (Taccaceae) versus Cochlospermum tinctorium A. Rich (Bixaceae)
Get PDFTacca leontopetaloides (Taccaceae) and Cochlospermum tinctorium (Bixaceae) are herbaceous plants that are used as non-conventional food in period of famine. T.leontopetaloides tuber and Cochlospermum tinctorium root transformed into powder in order to evaluate bioavailability of essential minerals contained in these vegetable organs versus antinutrients. Current methods of chemical analysis were used in laboratory to determined mineral and antinutrients content, and statistical software used to plot discrimination between data. Results indicated differences between mineral and antinutrient contents in two herbaceous plants. Major antinutrients in tacca tubers are saponins (4.08±0.24%) and phytate (0.46±0.02%); but C. tinctorium contained an enormous amount of phenolic compounds equivalent gallic acid (4,46±0.12%) and phytate (0.62±0.07%). Only Ca and Mg were found bioavailable in tacca and in C. tinctorium. Mineral bioavailability depends on mineral content versus antinutrient one
Ilocolic Volvulus: A Rare Complication of Chilaiditi Syndrome
Get PDFChilaiditi's syndrome is a rare condition where a segment of the digestive tract becomes trapped between the liver and the diaphragm, often without symptoms, making diagnosis challenging. However, it can lead to severe complications such as abdominal pain, bowel obstruction, or even perforation, necessitating prompt medical attention. In the presented case, a 54-year-old man with a significant surgical history developed acute abdominal pain due to this syndrome, leading to necrosis and perforation of an old intestinal anastomosis. Imaging confirmed the diagnosis, and surgery was required to resect the affected area. The condition has a low global incidence and primarily affects elderly males, with diagnosis relying heavily on imaging techniques like abdominal CT and chest X-ray to differentiate it from other critical conditions
Promoting Sexual and Reproductive Health and Rights (SRHR) for Women and Girls in Nigeria
Get PDFSexual and Reproductive Health and Right (SRHR), as it affects women, has continued to be a topical issue in Nigeria. In many cases, Nigerian women and girls are exposed to a number of factors that have created an inconducive atmosphere for ensuring that their sexual and reproductive rights are protected and guaranteed. Issues such as early marriage, poverty, maternal mortality, rape, lack of access to SRHR services and information, continue to prevent these individuals from fully exercising their fundamental rights. Addressing these challenges requires concerted efforts from various stakeholders, including the government, civil society organizations, healthcare providers, and communities. Policies and programs aimed at promoting gender equality, ending child marriage, and preventing gender-based violence are crucial for safeguarding women and girls' SRHR. Improving access to SRH services, including education and information, and ensuring the availability of skilled healthcare providers are essential steps towards empowering women and girls to exercise their SRHR. Furthermore, community engagement and awareness-raising initiatives are essential for challenging harmful social norms and promoting positive attitudes towards women's rights and sexuality. By addressing the multifaceted barriers to SRHR in Nigeria, a more conducive environment can be created where women and girls can fully realize their sexual and reproductive health rights, leading to improved health outcomes and overall well-being
Brain Manifestations of Six Mental Elements in Neuropsychoanalysis
Get PDFBackground: It was added the reticular noradrenergic(NA), serotonergic(5-HT), dopaminergic(DA) and acetylcholinergic (ACh) systems to regulate sleep and emotional balance among unconscious (emotions) / preconscious (memories) / conscious in Freudian topographic theory for depression and anxiety, while it was added by Cai the reticular DA and ACh systems to schizophrenia in Freudian structural theory of id (motivation) / ego (selfishness) / superego (knowledge), with these reticular systems altogether termed as the fourth element “reticula" for neuropsychoanalysis.Purpose: It was attempted to unify the classification of elements in neuropsychoanalysis as the world people expecting.Methods: It was searched the papers from Pubmed and Baidu, and then classified and summarized.Results and Discussions: (a) It is classified superego(knowledge) in structural theory to memories in topographic theory. (b) In schizophrenia, it is suggested that the elevated DA in associative striatum integratively inhibit the memories-associated comprehension of perception, compatible with the downstream hypoconnectivity between prefrontal-limbic cortices and thalamic nuclei, whereas the opposite assumption wrong as activation of associative striatum by DA would correct memories, improve comprehension and ameliorate schizophrenia following repetition of reward/punishment. (c) It is the schizophrenic hyperconnectivity between somatomotor cortex and thalamic nuclei that indicates overactivation of simple ego action, while schizophrenic hyperconnectivity between auditory network and thalamic nuclei that represents alteration of perception including hallucination. (d) In depression, it is divided the emotional balance into aversion and motivation, while conscious into perception and behavior(including ego). (e) In depression, it is unbalanced in limbic activities, sleep and NA/5-HT/DA.Conclusions: It is classified the neuropsychoanalysis into six elements as aversion/motivation/perception/behavior/memories/reticula, unified for depression and schizophrenia
AI and Digital Twin Transforms in the Construction of Precision Medical Model: Healthcare Management in Smart Cities
Get PDFIn recent years, the integration of artificial intelligence (AI) and digital twin (DT) is driving a new revolution in the healthcare field. Precision medical methods can utilize the complex computing techniques and models of AI, combined with various genetic and non-genetic data, to enable the system to reason and learn under the drive of data and algorithms, assisting clinical doctors and researchers in making more accurate related decisions. Research has shown that AI and DT has shown enormous technological application space in genomics, clinical cancer treatment, molecular imaging, and other fields, but it also faces potential challenges such as system bias, correlation limitations, algorithm black boxes, and unfairness. This requires the use of AI and DT transformations to build a precision medical intelligent system, which can update, capture, and study real-world data in real-time and simulate in DT. This study proposes that real-world data should be constructed from information system data and medical knowledge data from various hospitals, combined with the roles of real-world evidence (RWE), randomized clinical trial (RCT), genetic research, and AI technology in precision medicine, to innovatively design a precision medical smart system in the social 5.0 smart city. This work also proposes the structure and operating standards of the smart system, providing innovative ideas and contributions for the future construction of precision medical smart systems in society
Spectrum of Nodal and Extra Nodal Lymphoma in a Regional Cancer Centre, Odisha, India
Get PDFLymphoma encompasses a large group of cancers, ranking 7th among the common malignancies. Commonly, lymphoma originates in the lymph nodes. Infiltration of malignant lymphomatous cells in organs other than the lymph node is termed as Extra Nodal Lymphoma. In this retrospective study of 253 cases of Lymphoma, the spectrum of histopathological features of Extra Nodal Lymphoma is illustrated to ascertain the histological and anatomical distribution of ENL & NL. ENL constituted about 16% of all lymphomas studied during this period. Gastro-intestinal tract is the most common anatomical site in ENL. The peak incidence is found among middle aged population. Cervical Lymph Node is the most prevalent node involved in case of Nodal Lymphoma. This study was carried out at the Acharya Harihar Regional Cancer Centre (AHRCC), Cuttack, Odisha, India. This activity outlined the epidemiological and morphological evaluation of ENL & NL. future research will look to focus and highlight the survival analysis and genetic profile to understand the complex biology of primary Extranodal Lymphoma
De Novo Intra-Anal Pilonidal Sinus: A Case Report
Get PDFPilonidal sinus is a disease in which chronic inflammation occurs due to involution of hair fragments into skin. Intra-anal pilonidal sinus is extremely rare condition and only 10 cases have been reported in literature, where most of them had previous history of anal or pilonidal sinus surgery. A 22 years’ male presented with the complaints of purulent discharge per rectum and itching around peri anal region on and off for 3 months. No history of previous peri anal surgery or pilonidal surgery. Proctoscopy revealed opening of sinus at 6’o clock position. Intra operatively sinus tract laid open and tuft hair was removed and cavity curetted. His post operative period was uneventful