International Journal Multidisciplinary (IJMI)
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122 research outputs found
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ANTIBACTERIAL EFFICACY OF ALLIUM SATIVUM AGAINST MULTIDRUG-RESISTANT BACTERIAL PATHOGENS AND ITS SYNERGISTIC INTERACTION WITH CONVENTIONAL ANTIBIOTICS
Full text linkObjective: This study aims to investigate the potential of Allium sativum (garlic) as an alternative antibacterial agent in the context of rising antibiotic resistance. Method: A comprehensive literature review was conducted, focusing on in vitro and in vivo studies that evaluate the antimicrobial efficacy of Allium sativum against multidrug-resistant (MDR) bacterial strains. Sources included peer-reviewed journals in microbiology, pharmacology, and ethnomedicine. Results: The analysis reveals that Allium sativum exhibits broad-spectrum antibacterial activity, particularly effective against Gram-positive and Gram-negative MDR bacteria. Its bioactive compounds, such as allicin, disrupt bacterial cell walls, inhibit enzyme activity, and prevent biofilm formation. The low incidence of side effects and the affordability of garlic make it a viable candidate for complementary or integrative antimicrobial therapies. Novelty: This study highlights the relevance of traditional medicinal plants in modern antimicrobial drug discovery, emphasizing Allium sativum as a sustainable, natural, and accessible alternative in combating antibiotic-resistant infections, with implications for public health and pharmaceutical innovation
DETERMINANTS OF INNOVATION STRATEGY ON BUSINESS PERFORMANCE WITH COMPETITIVENESS AS AN INTERVENING VARIABLE IN BATIK MSMES IN EAST JAVA
Full text linkObjective: The purpose of this study was to examine; (1) the effect of product innovation, process innovation, technological innovation, organizational innovation and service innovation partially on competitiveness (2) the effect of competitiveness on business performance (3) the effect of product innovation, process innovation, technological innovation, organizational innovation and service innovation partially on business performance (4) the effect of product innovation, process innovation, technological innovation, organizational innovation and service innovation partially on business performance through competitiveness in Batik MSMEs in East Java. Methods: The data processing method in this study used Statistical Package for the Social Sciences (SPSS) software version 27 and path analysis with Structural Equation Modeling (SEM) modeling PLS program version 4.00. The population in this study was 657 Batik MSME owners in East Java, with the calculation of the Slovin formula found as many as 249 samples. Results: The results showed that; (1) product innovation, process innovation, technological innovation, organizational innovation and service innovation partially have a positive and significant effect on competitiveness (2) competitiveness has a positive and significant effect on business performance (3) product innovation, process innovation, technological innovation, organizational innovation and service innovation partially have a positive and significant effect on business performance (4) product innovation, process innovation, technological innovation, organizational innovation and service innovation partially have a positive and significant effect on business performance through competitiveness in Batik MSMEs in East Java. Novelty: The novelty in this study lies in the use of the Digital Maturity Index as a new indicator in measuring business performance
ANALYTICAL STUDY ON THE USE OF BIOSECURITY SYSTEMS IN CHICKEN FARMING TO PREVENT DISEASE
Full text linkObjective: This research aims to analyze the implementation of biosecurity systems in chicken farms and provide strategies to improve their effectiveness. The goal is to support a safer, more productive, and sustainable farming ecosystem while reducing the risk of disease outbreaks that could threaten the livestock sector. Method: A qualitative approach was used with library research or literature study as the primary method. Data sources were collected from scientific journal articles and research reports to gain a comprehensive understanding of biosecurity practices in chicken farming. Results: The study found that the application of biosecurity systems in chicken farms varies based on farm size, with large-scale farms demonstrating better implementation due to greater resources, knowledge, and technical support. Effective strategies for improving biosecurity include training programs for farmers, providing adequate facilities, financial assistance, and supervision. However, small-scale farms face significant challenges, including limited funds, lack of knowledge, inadequate facilities, and resistance to change, which hinder optimal biosecurity implementation. Novelty: This study highlights the importance of a collaborative approach involving farmers, governments, and stakeholders to improve biosecurity practices. It also emphasizes the need for tailored strategies that address the unique challenges faced by small-scale farms, offering actionable solutions to enhance sustainability and disease prevention in the poultry industry
RELIGION NARRATIVE IN THE FILM "HATI SUHITA"
Full text linkObjective: This study examines the representation of religious narratives in the film Hati Suhita. The research aims to analyze how religious values are conveyed through cinematic elements, including dialogue, scenes, and visual aspects such as setting, symbols, and costumes. Method: A qualitative approach was employed using Norman Fairclough’s Critical Discourse Analysis. This method enables an in-depth examination of how religious narratives are structured and communicated within the film. The study focuses on three core aspects of Islamic teachings: Aqidah (faith), Syariah (Islamic law), and Akhlak (morality). Results: The findings indicate that religious narratives are presented through key Islamic teachings. Aqidah is depicted by emphasizing faith in the Almighty and the concept of divine destiny. Syariah is conveyed through dialogues and expressions that illustrate religious practices and their proper implementation within an Islamic framework. Akhlak is integrated holistically, incorporating both religious doctrine and universal humanistic values, which shape the overall moral message of Hati Suhita. Novelty: This study highlights the multifaceted representation of Islamic teachings in contemporary Indonesian cinema. By analyzing Hati Suhita through the lens of Critical Discourse Analysis, the research provides fresh insights into how religious values are interwoven into film narratives, not only as theological constructs but also as cultural and social influences within a modern cinematic context
ECOLOGICAL ANALYSIS AND CHARACTERIZATION OF DEW SIZE AND TYPES IN NATURAL ECOSYSTEMS
Full text linkObjective: Dew is a significant natural phenomenon in wild ecosystems, serving as an indicator of environmental conditions and weather changes. However, classification of dew based on size remains unclear and has not been extensively studied systematically. This study aims to classify dew types by size and describe appearance patterns of each type in the wild. Method: This study employs a qualitative phenomenological research approach. Results: Dew in the wild can be classified as large dew (>4.1 mm), small dew (1–4 mm), sand dew (0.5–0.9 mm), and fine dew (<0.4 mm). Large dew does not appear daily but commonly occurs after drizzles or heavy rain of varying duration. Small dew is present daily with amounts varying according to environmental conditions. Sand dew occasionally appears, mainly adhering to green grass leaf edges and can serve as an indicator of heat followed by rainfall. Sand dew sizes range from 0.5 to 0.9 mm with an average of 50 to 120 droplets per grass leaf. Dew classification by size can be used as a tool to monitor environmental conditions in the wild. The presence of sand dew on green grass leaves has potential as a visually observable environmental indicator. Novelty: This study uniquely identifies four distinct dew categories large dew, small dew, sand dew, and fine dew and correlates their presence with environmental and weather conditions
SYNTHESIS, AND BIOLOGICAL ACTIVITIES OF SOME SCHIFF BASES DERIVATIVES
Full text linkObjective: This study aims to synthesize and evaluate the biological activities of four Schiff base compounds derived from the condensation of benzaldehyde and selected amine derivatives, with a focus on determining their anticancer, antibacterial, and antifungal potentials. Method: Four compounds—namely compound 1 [(E)-1-(4-chlorophenyl)-N-(6-methoxybenzo[d]thiazol-2-yl)methanimine], compound 2 [(E)-4-(((6-methoxybenzo[d]thiazol-2-yl)imino)methyl)phenol], compound 3 [(E)-5-((2-methylbenzylidene)amino)-2,3-dihydrophthalazine-1,4-dione], and compound 4 [(E)-5-((2-hydroxybenzylidene)amino)-2,3-dihydrophthalazine-1,4-dione]—were synthesized and subjected to in vitro screening. Results: Compound 1 exhibited the strongest anticancer activity, outperforming the other derivatives. Compounds 1 and 2 showed pronounced antibacterial effects against Staphylococcus aureus, while compound 4 demonstrated activity against Escherichia coli. Compounds 3 and 4 also displayed significant antifungal inhibition against Candida albicans. Novelty: The study identifies specific structure–activity relationships among newly synthesized Schiff bases, highlighting distinct bioactive profiles and offering promising lead compounds for future therapeutic development
A SUBJECT REVIEW ON THE: ADVANCING ELECTRONIC DEVICES WITH CONDUCTIVE POLYANILINE NANOCOMPOSITE THIN FILMS: CHARACTERISTICS, AND APPLICATIONS
Full text linkObjective: This study aims to provide a comprehensive review of conductive polyaniline (PANI), emphasizing its synthesis, characterization, nanocomposites, thin films, and diverse applications. The primary goal is to compile the latest findings and advancements, highlighting PANI's potential in materials science and electronics due to its high conductivity and adaptability. Method: The study explores various PANI synthesis methods, including chemical synthesis and electrochemical polymerization. Detailed analyses are conducted on PANI’s properties, such as surface morphology, conductivity mechanisms, doping processes, and structural characteristics. Techniques for manufacturing PANI thin films, including deposition methods and surface modifications, are reviewed alongside characterization approaches used to evaluate their properties. Results: PANI nanocomposites are examined, focusing on their integration into nanomaterials and resulting characteristics. Applications in electronic devices, sensors, biosensors, energy storage, organic electronics, and flexible electronics are discussed extensively. Additionally, methods for enhancing PANI’s performance and characteristics are highlighted, underscoring its practical utility in advanced technologies. Novelty: This review consolidates recent developments in PANI research, offering in-depth insights into its synthesis, structural attributes, and application spectrum. By addressing PANI’s role in emerging technologies such as flexible and wearable electronics, the study underscores its significance and potential for future advancements in materials science and electronic applications
THE EFFECT OF UREA FERTILIZER LOADED ON HYDROGEL COMPOUNDS PREPARED FROM GELATIN IN INCREASING NITROGEN AVAILABILITY AND REDUCING AMMONIA VOLATILIZATION IN SOIL
Full text linkObjective: This study aims to evaluate the effect of urea fertilizer encapsulated with hydrogel compounds prepared from gelatin on increasing nitrogen availability and reducing ammonia volatilization in soil. Method: A laboratory experiment was conducted using urea fertilizer coated with hydrogel composites at different encapsulation ratios of gelatin to sodium alginate (1:1, 1:2, and 2:1), designated as G1, G2, and G3, respectively. The hydrogels were crosslinked with 7% calcium chloride (CaCl₂) and applied to two soil types, clay loam and sandy loam, at a nitrogen rate of 1000 mg N kg⁻¹ soil. The samples were maintained at field capacity and incubated for 3, 6, 9, 12, 15, 20, and 30 days, during which ammonia volatilization and available nitrogen were measured. Results: The results demonstrated that urea encapsulated with hydrogel compounds significantly reduced ammonia volatilization and enhanced nitrogen availability compared to uncoated urea. Among the treatments, the 2:1 ratio (G3) showed superior performance in minimizing nitrogen losses and improving soil nitrogen retention. Novelty: This study introduces an innovative approach to nitrogen management through hydrogel-based encapsulation, highlighting its potential to improve fertilizer efficiency and mitigate environmental impacts associated with ammonia volatilization
THE ROLE OF COMPLIANCE AND GRATITUDE IN IMPROVING THE PSYCHOLOGICAL WELL-BEING OF EARLY CHILDHOOD EDUCATION TEACHERS: A LITERATURE REVIEW
Full text linkObjective: This study aims to comprehensively review the role of obedience and gratitude in improving the psychological well-being of non-civil servant early childhood education (PAUD) teachers, particularly in Islamic boarding schools (pesantren). Early childhood education (PAUD) teachers face significant challenges related to financial well-being, employment status, and high workloads, which have the potential to cause stress and reduce psychological well-being. Method: Through a literature review, this study found that obedience based on self-awareness, religious values, and moral responsibility can provide a sense of security, order, and satisfaction in carrying out tasks. Results: Meanwhile, gratitude has been shown to play a significant role in fostering positive emotions, reducing stress, strengthening social relationships, and helping teachers interpret limitations as a form of devotion. In the context of Islamic boarding school culture, the value of obedience reflected in the philosophy of "Bhuppa' Bhâbbhu' Ghuru Rato" and gratitude rooted in religious teachings strengthen teachers' resilience to remain dedicated. Thus, it can be concluded that obedience and gratitude are important psychological factors that complement each other in maintaining the psychological well-being of PAUD teachers. Novelty: These findings have practical implications for schools, Islamic boarding school foundations, and the government in formulating development strategies and policies that support the welfare of non-civil servant PAUD teachers more comprehensively
THYROID AUTOIMMUNE DISEASE AND EFFECT ON DEVELOPMENT TO THYROID CANCER
Full text linkObjective: This study investigates the association between autoimmune thyroid diseases—specifically Hashimoto's thyroiditis (HT) and Graves' disease (GD)—and the development of thyroid cancer, with a primary focus on papillary thyroid carcinoma (PTC). Method: A comprehensive literature review was conducted to analyze epidemiological trends, immunopathological mechanisms, and tumor microenvironment factors linking autoimmunity to thyroid carcinogenesis. Results: The findings indicate a significant correlation between autoimmune thyroid disorders and increased incidence of PTC, suggesting that chronic inflammation may contribute to oncogenic genetic alterations in thyroid epithelial cells. Interestingly, HT appears to paradoxically confer favorable clinical outcomes, including reduced tumor aggressiveness, enhanced responsiveness to radioiodine therapy, and improved survival, likely due to heightened immune surveillance. Additionally, the presence of cancer-associated fibroblasts (CAFs) was associated with increased lymph node metastasis, highlighting their role in shaping a pro-tumorigenic microenvironment. Novelty: This study provides integrative insights into the dual role of autoimmunity in both promoting and modulating thyroid cancer progression, and underscores the importance of the tumor microenvironment—particularly CAFs—in influencing metastatic behavior in PTC