Journal of Medical Genetics and Clinical Biology
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    406 research outputs found

    PREPARING NANOPARTICLES USING SOME BIOLOGICAL METHODS AND STUDYING THEIR EFFECT ON SOME MYCOTOXINS

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    General Background: Mycotoxins, toxic substances produced by certain fungi and bacteria, pose significant health risks to humans and animals, necessitating effective remediation strategies. Specific Background: The use of environmentally friendly approaches to mitigate the impact of these toxins is crucial. Nanotechnology, particularly in conjunction with plant extracts, has emerged as a promising method for toxin remediation due to its cost-effectiveness and efficiency. Knowledge Gap: Despite the potential of nanomaterials in mycotoxin management, there is limited research exploring the interaction between plant extracts and nanotechnology in inhibiting toxin-producing fungi. Aims: This study aims to investigate the efficacy of zinc oxide nanomaterials synthesized from mint plant extracts in mitigating the effects of mycotoxins and inhibiting the growth of mycotoxin-producing fungi. Results: Mint leaves were collected from various locations in Al-Qadisiyah Governorate over an eight-week period. The extracted plant materials were used to synthesize zinc oxide nanoparticles, which demonstrated significant inhibitory effects on the growth of specific fungi responsible for mycotoxin production, thereby reducing mycotoxin formation. Novelty: This research highlights the innovative application of mint-derived zinc oxide nanoparticles as a dual-action agent—suppressing fungal growth while simultaneously preventing mycotoxin synthesis. Implications: The findings provide valuable insights into sustainable agricultural practices and mycotoxin management, paving the way for the development of natural, eco-friendly solutions to enhance food safety and protect public health

    ALTERATIONS IN HEMATOLOGICAL INDICES IN ANTENATAL AND POSTNATAL MOTHERS WITHIN KERKUK PROVINCE, IRAQ

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    Objective: The purpose of this study is to examine changes in hemoglobin, packed cell volume, white blood cells, and platelet counts in Iraqi women from Kirkuk Province during the prenatal and postnatal phases. Methods: During the course of a year, 600 women attended Azadi Hospital in Kirkuk, including 300 pregnant women in the third trimester and 300 postpartum women. An automated analyzer was used to collect and analyze blood samples, and the outcomes were contrasted with those of a control group of 60 university students who were not pregnant. Results Hematological parameters showed notable alterations. During pregnancy, hemoglobin and packed cell volume dropped, but after delivery, they rose (p < 0.022). During pregnancy, the white blood cell count was significantly greater (p < 0.001), and it continued to rise after delivery. There was no discernible change in the platelet count. Instead of clinical situations, these deviations were ascribed to normal physiological processes. Novelty: This study contributes to better health monitoring and risk assessment for maternal care by shedding light on the typical hematological alterations that occur in Iraqi women throughout pregnancy and the postpartum phase

    ACCELERATION HEALING AND OSSEO-INTEGRATION PROCESSES OF CPTI IMPLANT BY COATING TEETH WITH COLLAGEN-POLYCAPROLACTONE FIBER SCAFFOLD

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    Objective: This study aimed to enhance osseointegration and healing by combining electrospinning techniques with collagen and polycaprolactone (PCL) as a coating for commercial pure titanium (CpTi) implants. Methods: In vitro experiments utilized glacial acetic acid as a solvent system to create collagen/PCL coatings with varying PCL concentrations (10%, 15%, 20% w/v). Morphological and physical characterizations were conducted using scanning electron microscopy (SEM), atomic force microscopy (AFM), and wettability tests. In vivo studies involved implanting collagen/PCL-coated CpTi cylinders into the femoral bone of New Zealand rabbits, followed by histological analysis at 2 and 6 weeks. Results: SEM revealed that scaffolds with higher PCL concentrations exhibited finer nanofiber structures (average diameter: 232 nm) and enhanced hydrophilicity and roughness. Histological analysis demonstrated significant osteogenic activity and basal bone formation, with well-formed bone plates observed at 6 weeks for implants coated with 20% collagen and 20% PCL. Novelty: The study highlights the potential of electrospun collagen/PCL coatings to create optimal surface properties for dental implants, achieving improved tissue integration and healing outcomes. This innovative approach demonstrates the versatility of electrospinning for fabricating fibrous scaffolds that can incorporate therapeutic agents, offering transformative implications for regenerative medicine and implantology

    METHODS OF CORRECTING PSYCHIC DEPRIVATION IN THE PUPILS OF THE “KINDNESS” HOUSE

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    This article will talk about the specific psychological characteristics of the Breeders of the Houses of “kindness”, the tasks set before the state and society in preparing them for an independent life as a full-fledged person. Ham also touched on the work activities of a practical psychologist with children and adolescents brought up in orphanages

    DETERMINATION OF THE EFFECTIVENESS AND USE OF SOME ANTHELMINTIC DRUGS IN THE TREATMENT OF FASCIOLOSIS IN GOATS

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    In this article, the effectiveness of the newest anthelmintic drugs in the treatment of fasciolosis in goats in the irrigated areas of Surkhandarya region was determine

    Effect of use of natural biologically active substances on shelf life of pomegranate fruits

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    In this article, research on the effect of biologically active substances on the shelf life of pomegranate fruits and scientific data on various diseases, storage temperature, and relative humidity changes of pomegranate fruits during storage are presente

    EARLY COMPLICATIONS OF ACUTE MYOCARDIAL INFARCTION WITH ST SEGMENT ELEVATION

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    Myocardial infarction is a dangerous disease that causes irreversible changes in the heart. The disease mainly occurs in people over 50 years of age. According to statistics, in general, about 60% of people over the age of 65 have experienced a heart attack. However, younger people are also at risk of the disease. Assess the true natural history of acute myocardial infarction is difficult for a number of reasons: the possibility of hidden infarction, the high frequency of acute coronary death outside the hospital and the difference methods for diagnosing this condition

    SPECIFIC FAUNISTIC AND TAXONOMIC CHARACTERISTICS OF HELMINTHS OF SMALL HORNED CATTLE OF KARAKALPAKSTAN

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    The article presents information on the species composition of small horned cattle helminths, their systematic status, distribution, seasonal dynamics, extent of invasion and intensity of invasion in the conditions of Karakalpakstan. As a result of the study of helminths of small horned cattle of Karakalpakstan and the analysis of published literature, it was noted that 37 types of helminths parasitize small horned cattle. Of these, 34 species were found in sheep and 31 species in goats. The listed helminths belong to 25 genera, 16 families, 9 suborders, 8 families, 3 classes and 2 types of fauna. 26 types (70.2%) of 37 types of helminths parasitizing small horned cattle belong to nematodes, 8 types (21.6%) to cestodes and 3 types (8.1%) to trematode

    MODERN VIEW TO OPTIMIZATION OF DIAGNOSTICS OF PARKINSON'S DISEASE

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    Parkinsonism is one of the most significant problems of clinical neurology, both due to its high prevalence in the world's populations and due to the significant disability of patients. The work analyzes the diagnosis of Parkinson's disease (as well as other neurodegenerative diseases) at the prodromal stage. A review of methods for preclinical and early clinical diagnosis of PD shows that the study of prodromal markers and criteria for the premotor phase of PD will make it possible in the future to significantly change the course of the disease using neuroprotective therapy at the stage preceding the death of a significant number of dopaminergic neurons of the substantia nigra

    BIRTH PHOTOGRAPHY AS A NORMAL MATERNITY FACILITY AT PMB

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    Birth photography is a new form of birth art, the emergence of birth photography as an expression of a woman's birth experience that is centered on women. Photos become a means of imaginative adventure for human experience, communication between humans and themselves, between people and even between generations. This birth memoir is a form of celebration and gift for future children, parents, or anyone else for the moment of childbirth which only happens once in a woman's life even if there are subsequent births. With current technological advances, birth documentation as a medium for capturing beautiful memories of childbirth can be easily done, using a camera or a smartphone. The data source in this study uses a literature review method which comes from several sources, both national and international journals, using published articles from Google Scholar, Radiation Oncology Journal, PubMed, and Elsevier. In this research, birth photography is used as a facility for mothers going through normal childbirth. The aim is to entice mothers to become more interested and brave in going through natural childbirth with professional midwives at PM

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    Journal of Medical Genetics and Clinical Biology
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