Journal of Medical Genetics and Clinical Biology
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THE PREVALENCE OF URINARY TRACT INFECTIONS AND THE AGENTS RESPONSIBLE FOR THEM IN PREGNANT WOMEN IN THE PROVINCE OF KARBALA
Get PDFAlong with anemia and hypertension, urinary tract infections (UTIs) are among the most frequent medical problems of pregnancy, occurring in between 5% and 10% of pregnancies. This study set out to ascertain the frequency of urinary tract infections (UTIs) and the presence of uropathogens in expectant mothers. 417 urine samples were examined between December 2021 and August 2022 of that research period. When a urinary tract pathogen grew to at least 10 5 CFU/ml in a culture of a midstream urine sample, the diagnosis of UTI was made. Biochemical assays were used to identify the isolated microorganisms. According to the results, 49.4% of expectant mothers had a UTI. The most often isolated organism was E. Coli (56.79%), which was followed by Proteus sp (5.8%), Pseudomonas sp (6.3%), and Klebsiella sp (19.9%).
THE PRESENCE OF HEAVY METALS IN USED CLOTHES AND THEIR IMPACT ON HUMAN HEALTH
Get PDFThe research aims to detect the presence of heavy elements in used clothes and to educate people about their dangers and the diseases they carry in order to provide some solutions and recommendations for this problem. To achieve this goal, laboratory tests (atomic spectrometer) were conducted, which included 12 samples from different areas of Diwaniyah Governorate on 2/2/2021. The samples came in varying proportions. The percentage of arsenic increased in the intersection street by 30% and decreased in Alawi Street by 25%. As for the cadmium element, its concentration increased in Alawi Street by 20% and decreased in Alawi Street by 10%. As for lead, its percentage increased in the intersection street by 15% and decreased in Alawi Street by 10%. This difference is due to the presence of a fuel filling station behind the intersection street, so the percentage was greater. The quality of the clothes was estimated to be low, bad and dangerous to human health. Therefore, we recommend the necessity of carrying out sterilization operations and increasing monitoring of the places of their import and display to ensure the efficiency of the treatment and sterilization facilities
 
A COMPARATIVE STUDY OF THE QUALITATIVE CHANGES IN THE LEVELS OF IL-4 , IL-6 AND IL-10 AND THEIR RELATIONSHIP TO HEMATOLOGICAL PARAMETERS IN CHILDREN WITH E. VERMICULARIS INFECTION
Get PDFBackground; Enterobiasis (pinworm infection) caused by Enterobius vermicularis is a common parasitic infection prevalent worldwide especially in children. It causes many important symptoms and can lead to digestive problems and lead to malnutrition in children. Aims of the study; Knowing the relationship between levels of cytokine and the severity of infection in children and the extent of the impact of the infection on the child’s health in Iraq. Methodology; A Case-control study included 100 children suffering from infection with the worm E.vermicularis. The ages of the participants ranged from 3 to 10 years. The study included 50 healthy children matched in age and sex to the patient group. 5 ml of blood was collected from each participant at Al-Haboubi Teaching Hospital and at Nasiriyah General Hospital for the period between 3/1/2024 to 10/3/2024. CBC assay using a Sysmex device. Interleukins were examined using enzyme-linked immunosorbent assay. Result; The results showed that there was no statistical significance in age among the participants. While the results of WBC and CRP were significantly high in the patient group, in contrast to PCV and Hb which were significantly low. While interleukin 4 and interleukin 6 results showed a significant increase in the patient group, while interleukin 10 showed a significant decrease. Conclusions; High levels of biomarkers, indicate the immune response that causes by infection with the worm. Anemia due to the pathophysiology of inhibiting appetite and lack of absorption in Intestines for nutrients
SKIN THERAPY USING COLD ATMOSPHERIC PLASMA
Get PDFBackground: Maintaining skin integrity is essential for protecting against external agents, microorganisms, and dehydration, while also serving social and aesthetic functions. Recent advancements in skin care have introduced innovative technologies, including Cold Atmospheric Plasma (CAP), which shows promising results in dermatology. Specific Background: CAP technology, based on physical principles, has emerged as a novel approach in skin treatments, offering potential benefits for aging prevention and skin care. This interdisciplinary field encompasses physics, biology, chemistry, and biochemistry, presenting a complex landscape. Knowledge Gap: Despite its potential, there is limited comprehensive analysis of CAP's interactions with skin, its effects, and its practical applications in cosmetic dermatology. Aims: This research aims to provide a broad survey of CAP's interactions with skin by discussing the basic structure and functions of the skin, the foundational principles of CAP, and its physical and chemical properties. The study will analyze CAP parameters to highlight known effects and explore potential applications in skin treatment. Results: The review reveals that CAP exhibits versatile applications in dermatology, including direct treatment of superficial lesions, indirect treatment via plasma-activated media, and combined use with other therapies. CAP has shown promise in optimizing intact skin, facilitating transdermal drug delivery, and minimizing side effects. However, challenges remain in integrating CAP into routine clinical practice. Novelty: This overview synthesizes current knowledge and emerging potential of CAP technology in skin biology, offering a comprehensive evaluation of its effects and applications. Implications: The findings underscore CAP's potential to revolutionize skin care and dermatological treatments. Addressing the existing challenges and expanding research could enable CAP to become a valuable tool in both therapeutic and cosmetic dermatology
THE PREVALENCE OF INTESTINAL PARASITIC INFECTIONS AMONG PEDIATRIC PATIENTS IN KUT, IRAQ: A COMPARATIVE STUDY BY MEANS OF MICROSCOPY AND MULTIPLEX PCR
Get PDFIntestinal parasitic infections (IPIs) continue as a substantial public health issue in evolving nations, with pediatric population’s presence particularly susceptible. This study examines the prevalence of Entamoeba histolytica, Giardia lamblia, and Cryptosporidium parvum among children in Kut, Iraq, using both conventional microscopy and Multiplex PCR methodologies. A total of 257 stool specimens were procured from children aged 0 to 14 years crossways various hospitals and healthcare institutions. The specimens underwent an initial macroscopic and microscopic evaluation, subsequently followed by DNA extraction and examination by Multiplex PCR to supplement the detection capabilities for parasitic pathogens. The collective infection rate was determined to be 42.41%, with a larger prevalence experiential in females (49.24%) when compared with males (35.20%). Age-group analysis indicated that children aged 12 to 14 years showed the highest infection rate (60.00%), while the lowest prevalence was renowned in children under three years of age (37.50%). A proportional analysis between urban and rural environments revealed a heightened infection prevalence in rural locales (55.17% vs. 41.18%). The diagnostic efficiency of microscopy and Multiplex PCR confirmed considerable concordance, with Pearson correlation coefficients above 0.99 for all three parasites, so representative a healthy contract between the two diagnostic approaches. Nevertheless, Multiplex PCR shown a slightly superior detection rate for Entamoeba histolytica, Giardia lamblia, and Cryptosporidium parvum. These results emphasize the authoritative for the addition of molecular diagnostic practices into standard clinical repetition to improve the sensitivity and accurateness of IPI detection, particularly within resource-constrained environments
NATURAL PRODUCT MELON PULP AND ITS USE AS A NUTRIENT
Get PDFObjective: This study explores the nutritional composition, health benefits, and traditional and modern uses of melon pulp, known as qovun qoqi, a culturally significant food in Central Asia. Methods: A descriptive analytical approach was utilized, examining existing literature on melon varieties (Cucumis melo L.) to assess their vitamin, mineral, and antioxidant content, alongside bioactive properties. Qualitative data analysis further contextualizes the historical significance and evolving applications of melon pulp, especially in the context of traditional preparation methods and contemporary uses in nutraceutical and cosmetic products. Results: Findings reveal melon pulp as a nutrient-dense, hydrating ingredient rich in vitamins, minerals, and antioxidants, beneficial for bodily functions, skin health, and chronic disease prevention. Notably, the study addresses challenges in its usage, such as seasonality and handling. Novelty: By synthesizing both nutritional data and cultural perspectives, this research underscores the relevance of melon pulp in modern health-focused diets and as a versatile component in natural product industries. This work contributes to the growing recognition of traditional foods in sustainable health practices, emphasizing the potential of melon pulp as a valuable, natural ingredient for diet and wellness products
PARAPROSTHETIC RECURRENT VENTRAL HERNIAS AND THEIR SURGICAL CORRECTION
Get PDFObjective: To conduct a comparative analysis of macro- and microscopic morphological changes in tissues in patients with recurrent ventral hernias and to improve surgical methods for managing these cases. Methods: Patients were divided into two groups based on prior hernioplasty techniques: Group I (n=52) received tension methods, while Group II (n=26) underwent non-tension prosthetic methods. Clinical and instrumental analyses, including CT scans and morphological assessments of tissue around prostheses, were performed to evaluate recurrence patterns and inflammation levels. Results: Findings revealed that complete relapses frequently followed tension hernioplasty, while non-tension methods resulted in partial recurrences along the prosthesis contours. Tension methods showed significant void formation and inflammatory responses around the prostheses, while non-tension techniques led to a mature connective tissue response. The recurrence rate was notably lower (3.8%) in patients treated with improved non-tension methods, such as "onlay" without defect suturing and "onlay + sublay" with duplication. Novelty: This study offers insights into morphological differences in tissue responses based on hernioplasty techniques, supporting improved surgical methods for recurrent hernias. By enhancing tension-free techniques, recurrence rates were reduced from 15% to 3.8%, underscoring the clinical benefit of tailored approaches in recurrent ventral hernia management
Studying The Interaction of Laser with Human Tissue
Get PDFA laser is amplified light beam to emit radiation. these rays are used in surgery by accurately projecting laser light to remove diseased tissue or bleed blood vessels by heating the target cells until they explode. The laser is used medically under objective or complete anesthesia. There are many types of lasers such as carbon dioxide laser, YAG laser, and argon beam, and each type of laser has a specific use, and each type of surgery and tissue has a special color of laser light. the uses of the laser in the surgery are multiple. brain and liver tumors can be removed while not to damage the healthy tissue surrounding the tumors. Lymphatic vessels can be closed to reduce the spread of tumor cells and nerve endings to reduce pain after surgery, small bleeding blood vessels can be closed, in addition to removing warts and skin tumors. A general advantage of laser surgery is the absence of bleeding, reduced surgical infections, pain and wound size, and a short hospital stay. The recovery period after laser treatment depends on the type of pathological condition and the patient's health condition before treatment. In the end: the laser has successful surgical uses to obtain good results with minimal complications, and contrary to what is common, its medical uses are specific to certain diseases and not for all types of surgery. In addition, laser treatment requires modern and complex devices and experienced experts in their us
ASSOCIATION BETWEEN FEMALE HORMONES (FSH, LH, AND ESTROGEN) AS WELL AS HYPERLIPIDEMIA AND OBESITY IN AL- NAJAF HOLY CITY
Get PDFAn excessively high level of lipids, or fat, in the blood is called hyperlipidemia. The levels of hormones in females were examined, along with their correlation with elevated body fat and impact on cardiovascular conditions. The information was gathered in Najaf City between November 1, 2023, and December 20, 2023.
The results of this study showed that the concentrations for a hormone that promotes follicle development within samples had increased by 58%. LH increased in 50% of the samples that were analyzed. Better pubertal development has been associated with elevated FSH levels in the blood. Improved metabolism has been associated with an increase in blood FSH. Moreover, nonlinear correlations were found between adiposity measures and serum FSH levels
PREVALENCE AND ANTIBIOTIC RESISTANCE PROFILES OF BACTERIAL ISOLATED FROM BURN WOUND INFECTIONS
Get PDFBurn wound infections remain a sizeable assignment, especially because of the superiority of multidrug-resistant gram-negative organisms. The objective of this take a look at was to assess the superiority of bacterial infections in burn wounds, perceive the most not unusual bacterial species, and determine their antibiotic resistance profiles. A overall of eighty samples had been amassed from burn sufferers. Bacterial cultures were performed, and the isolated bacteria were identified using standard microbiological techniques. Antibiotic susceptibility testing was conducted using the disc diffusion method. In this study, 44 samples (73.3%) tested positive for bacterial growth. Pseudomonas sp. was the most commonly isolated bacteria (56%), followed by Staphylococcus aureus (22%) and others. Antibiotic resistance profiling revealed high resistance rates among the isolated bacteria, with Rifampicin showing the highest resistance rate (80%), followed by Cefotaxime (64%) and Amoxicillin (56%). The high prevalence of multidrug-resistant gram-negative organisms in burn wound infections underscores the urgent need for effective antibiotic management strategies. These findings highlight the importance of continuous surveillance of antibiotic resistance patterns and the development of tailored treatment protocols to mitigate the morbidity and mortality associated with burn wound infections. Additionally, there is a critical need for the development of new antimicrobial agents and infection control measures to combat the growing threat of antibiotic resistance in burn care settings