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Identifying subgroups in heart failure patients with multimorbidity by clustering and network analysis
Full text linkThis study presents a workflow for identifying and characterizing patients with Heart Failure (HF) and multimorbidity utilizing data from Electronic Health Records. Multimorbidity, the co-occurrence of two or more chronic conditions, poses a significant challenge on healthcare systems. Nonetheless, understanding of patients with multimorbidity, including the most common disease interactions, risk factors, and treatment responses, remains limited, particularly for complex and heterogeneous conditions like HF. We conducted a clustering analysis of 3745 HF patients using demographics, comorbidities, laboratory values, and drug prescriptions. Our analysis revealed four distinct clusters with significant differences in multimorbidity profiles showing differential prognostic implications regarding unplanned hospital admissions. These findings underscore the considerable disease heterogeneity within HF patients and emphasize the potential for improved characterization of patient subgroups for clinical risk stratification through the use of EHR data
The Laws of Nature: Rewriting the Myth of Demeter and Persephone in Peter Greenaway’s The Draughtsman’s Contract
No full textThis article considers the rewriting of the myth of Demeter and Persephone contained in Peter Greenaway’s 1982 film, The Draughtsman’s Contract. Via a reconsideration of the various versions of the myth present in both the film and its classical sources, the article argues that the film uses the myth to offer a nuanced meditation on the situation of women in both the seventeenth century (when the film is set) and the late twentieth century (when the film was made). Reflecting back across the centuries, the film highlights how interpretations of the myth of Demeter and Persephone have tended to be defined by particular social, legal, and technological formations, rather than by any kind of natural order (for which the myth itself provides a speculative aetiology). In Greenaway’s film, within the limits of their social and material situations, the female characters rewrite the terms of the myth to achieve a qualified autonomy within a deeply patriarchal society
Reading at the Limits of Poetic Form: Dematerialization in Adorno, Blanchot, and Celan
No full textHow does literary objecthood contend with the challenge of writing objects that emerge at an extreme limit of material presence? Jacob McGuinn delves into the ways literature writes this indeterminate presence in the context of pre- and post-’68 Paris, a vital moment in the history of criticism. The works of poet Paul Celan, philosopher Theodor Adorno, and writer Maurice Blanchot highlight how the complexities of reading such a dematerialized object are part of the indeterminacy of material itself. Indeterminate objects—glass, snow, walls, screens—are subjects Celan describes as existing in “meridian” space, while for Adorno and Blanchot, criticism not only responds to this indeterminacy but also takes it as its condition. Reading at the Limits of Poetic Form: Dematerialization in Adorno, Blanchot, and Celan shows how these readings simultaneously limit the object of criticism and outline alternative ways of thinking that lie between the models of critical formalism and historicism, ultimately revealing the possible materiality of literature in unrealized history, incomplete politics, and nondetermining thinking
News and misinformation consumption: A temporal comparison across European countries
Full text linkThe Internet and social media have transformed the information landscape, democratizing content access and production. While making information easily accessible, these platforms can also act as channels for spreading misinformation, posing crucial societal challenges. To address this, understanding news consumption patterns and unraveling the complexities of the online information environment are essential. Previous studies highlight polarization and misinformation in online discussions, but many focus on specific topics or contexts, often overlooking comprehensive cross-country and cross-topic analyses. However, the dynamics of debates, misinformation prevalence, and the efficacy of countermeasures are intrinsically tied to socio-cultural contexts. This work aims to bridge this gap by exploring information consumption patterns across four European countries over three years. Analyzing the Twitter activity of news outlets in France, Germany, Italy, and the UK, this study seeks to shed light on how topics of European significance resonate across these nations and the role played by misinformation sources. The results spotlight that while reliable sources predominantly shape the information landscape, unreliable content persists across all countries and topics. Though most users favor trustworthy sources, a small percentage predominantly consumes content from questionable sources, with even fewer maintaining a mixed information diet. The cross-country comparison unravels disparities in audience overlap among news sources, the prevalence of misinformation, and the proportion of users relying on questionable sources. Such distinctions surface not only across countries but also within various topics. These insights underscore the pressing need for tailored studies, crucial in designing targeted and effective countermeasures against misinformation and extreme polarization in the digital space
Philosophy is not a science: Margaret Macdonald on the nature of philosophical theories
Full text linkMy journey in science and art
Full text linkAn autobiography of the scientific and artistic journey of a computational chemist from the time of his undergraduate, postgraduate and academic time. It outlines various discoveries made regardless of the unemployment risks that young scientist face nowadays. Some discoveries where a matter of luck but other come after years of systematic studies. Strong bonds with scientists are formed from this scientific endeavor
Computer Quiz Games in General Chemistry for Engineering Majors in an English as a Second Language Environment
Full text linkHow Haag-tied is QFT, really?
Full text linkHaag's theorem cries out for explanation and critical assessment: it sounds the alarm that something is (perhaps) not right in one of the standard way of constructing interacting fields to be used in generating predictions for scattering experiments. Viewpoints as to the precise nature of the problem, the appropriate solution, and subsequently-called-for developments in areas of physics, mathematics, and philosophy differ widely. In this paper, we develop and deploy a conceptual framework for critically assessing these disparate responses to Haag's theorem. Doing so reveals the driving force of more general questions as to the nature and purpose of foundational work in physics
