Scholastic: Journal of Natural and Medical Education
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Detection and Correction of Hypokalemia in Patients with Refractory Chronic Heart Failure
No full textTreatment of heart failure (HF) is important in modern cardiology. One of the chronic heart problems in patients is the circulatory system. Due to the violation of neurohumoral regulation of blood circulation system in patients, the expansion function of peripheral blood vessels changes and the total resistance of peripheral blood vessels increases. Because of this, the ventricles of the heart are forced to increase their tension before contraction and after contraction. According to the conclusions of the World Health Organization, the incidence rate of diseases of the cardiovascular system takes the first place among the general morbidity and mortality rates. In 6-10% of cases, one of the reasons for hospital admission is the irregular intake of powerful diuretics and acute decompensation of CHF with hypokalemia. CHF was detected in more patients. In addition, every year more than 1,000 patients have CHF symptoms. As a result of the decrease in the pumping function of the heart in the body, excessive retention of water in the small and large blood circulation is detected, it has been proven to recommend diuretic drugs to patients with CHF. Causes inadequate blood circulation in the organs and tissues, initially at times of slight physical exertion, and later at rest. Disruption of neurohumoral mechanisms in the pathogenesis of CHF causes salt and water retention in the body. Water retention in the body, which in turn increases the amount of circulating plasma, and as a result, the end diastolic pressure in the left ventricle increases, leads to the development of heart failure [14,15]. In the initial stages of CHF, the main compensatory mechanism is the outflow of water and salts from the body. An increase in the amount of circulating blood leads to an increase in venous blood flow to the heart, which causes a temporary increase in left ventricular stroke volume
Aldosterone causes the body to retain water and sodium. Therefore, these neuro-humorous shifts initially have a compensatory nature, and at the next stages, they become pathological
Comparative Analysis of the Stress-Strain State of the Lower Jaw with Different Splinting Systems in Localized Periodontitis of Middle Gravity by Finite Element Modeling
No full textWhen creating structures for various purposes in all areas of activity, the finite element method (FEM) is commonly used. At present, the development of medical technologies without FEM is unthinkable. The essence of the method is the division of solid bodies into discrete finite elements that interact with each other only at the nodes. The method makes it possible to obtain the distribution of displacements and stresses on the analyzed model with the condition of specifying loads and boundary conditions. Boundary conditions provide adequate behavior of the model, forming interaction with the non-modeled environment. Calculations using the FEM are in great demand, since their use allows eliminating design flaws at the design stage, reducing the finishing time and the number of experiments
Syndrome of Emerging Polycystic Ovaries in Modern Gynecology
No full textPolycystic ovary syndrome (PCOS) is a chronic condition in which a woman does not have or rarely ovulates, i.e. a mature egg does not leave the ovary for fertilization by a sperm. Otherwise, this condition is called polycystic ovaries, or Stein—Leventhal syndrome. It is accompanied by reproductive disorders (inability to get pregnant and give birth to a child), metabolic disorders and psychological problems
Modern Concepts on the Effect of Alcohol Intoxication on the Activity of the Heart
No full textAccording to World health organization statistics, heart disease has been the leading cause of death for over 20 years. Heart disease today accounts for 16% of all deaths in the world. Since 2000 the number of deaths from cardiovascular diseases increased by more than 2 million and in 2019 reached almost 9 million. The purpose of this article is to analyze, summarize and draw conclusions from the information provided by the authors
Аsessment of the Intake of Titanium Dioxide into the Body with Food
No full textTitanium dioxide (TiO2) is used as a food additive (E171) and can be found in sauces, icing and chewing gums, as well as personal care products such as toothpaste and pharmaceutical tablets. Along with the ubiquitous presence of TiO2 and recent awareness of its potentially hazardous properties, there are concerns about its use in commercially available products.
Especially the nano-sized (<100 nm) fraction of TiO2 requires a more detailed assessment of potential adverse health effects after ingestion. A workshop organized by the Dutch Risk Assessment and Research Office (BuRO) highlighted uncertainties and gaps in knowledge regarding TiO2 absorption in the gastrointestinal tract, its distribution, potential for accumulation and induction of adverse health effects such as inflammation, DNA damage and tumor development. The purpose of this review is to identify and evaluate recent toxicological studies of dietary TiO2 and nanosized TiO2 in ex vivo, in vitro and in vivo in gastrointestinal experiments, and to postulate an adverse outcome pathway (AOP) after ingestion. In addition, this review summarizes the recommendations and results of the Bureau's 2018 expert meeting to provide input to the hazard identification and risk assessment process for TiO2 ingress
Causes of Otitis in Children and its Prevention
No full textinflammation of the middle ear, this disease, especially in young children, is a bit severe, the ear hurts a lot, the temperature rises, the hearing is much reduced, it causes complications to the brain and its membrane. possible
Economy of Punctuation in Uzbek Language
No full textIt is known that punctuation is a component of the writing system of a certain language, its careful acquisition and appropriate use in practice is important for written speech. Punctuation is considered one of the national cultural assets, and it is widely used by science and literature, publishing, and the press. The word punctuation is derived from the Latin punctium (point - point, sign, shape) and is used in three senses: the section teaching the system of punctuation marks, the rules of using punctuation marks and the meaning of punctuation marks. Punctuation is a set of legal rules about the use of punctuation marks, which teaches the quantity, function, system and order of punctuation marks
Management of Pregnant Women With Cervical Cancer
No full textPregnancy complicated by cervical cancer is determined in the case of primary diagnosis of cervical cancer during pregnancy or after 6-12 months after childbirth. The number of pregnancies complicated by cervical cancer is small. In 1-3% of women with cervical cancer, oncology was first diagnosed during pregnancy. Of these, about half were pregnant during the diagnosis of the disease, the rest - 6-12 months after childbirth.
It is not known whether pregnancy increases the risk of onset or progression of cervical cancer. However, elevated estrogen levels and human chorionic gonadotropin are thought to activate the pro-carcinogenic effect of human papillomavirus (HPV) infection. Other researchers believe that increased blood flow and lymphatic circulation in the early phase of pregnancy with a simultaneous decrease in specific immunity and cervical dilatation may contribute to the development of cervical cancer
The Impact of Low-Intensity Laser Therapy in Rhinosinusitis
No full textRhinosinusitis (RS) is a frequent problem in modern otolaryngology. But all the available methods do not make it possible to completely cure this pathology. The answer to this question may be an alternative treatment that is carried out on animals in order to find new technologies to eliminate RS. Little is known about alternative treatment options for rhinosinusitis. We sought to evaluate the effectiveness of low-intensity laser therapy (LILT) for RS in experimentally induced models of RS in rabbits, since the tissue of the nasal sinuses is almost identical to human
Some Features of Injuries of the Thoraco-Lumbar Spine
No full textThe number of injuries to the thoracic and lumbar spine remains at a consistently high level with a tendency to stable growth. The growth of such damage is primarily associated with the high urbanization of the population, an increase in road traffic accidents, the construction of high-rise buildings, and the use of high-tech household appliances. Modern views on diagnostic issues and tactical approaches to treatment require clarification. Therefore, work to improve the surgical treatment of the thoracic and lumbar spine is still relevant