Scholastic: Journal of Natural and Medical Education
Not a member yet
408 research outputs found
Sort by
Surgical Correction of Incomplete Anomalous Pulmonary Venous Drainage
No full textFor the period from 2001-2021. 149 patients aged 1.4 - 45 years with various anatomical variants of IAPVD were operated on in the Department of CHD Surgery of the RSSPSC named after academician V. Vakhidov and the clinic of the ASMI. The diagnosis of the defect was based on the analysis of a combination of data from clinical and special research methods, including echocardiography, multispiral computed tomography with contrast, and catheterization of the heart cavities with angiocardiography. Operations were performed from the median sternotomy and thoracotomy with the right lateral access, under cardiopulmonary bypass with pharmaco-cold cardioplegia. The types of surgery for partial anomalous drainage of the pulmonary veins were analyzed. Depending on the level of entry of the pulmonary veins and the location of the ASD, patients were divided into 4 groups: supracardial, cardiac, infracardial and displaced. 7 operated patients had an additional left-sided SVC opening into the coronary sinus
Features of Metabolic Status and Markers of Inflammation in Prolonged Neonatal Hyperbilirubinemia
No full textNeonatal hyperbilirubinemia during the newborn period has the most significant indicators in the structure of mortality and morbidity due to the toxic effect of bilirubin on the central nervous system and the newborn's body as a whole. Biochemical examination of blood serum is the most commonly used indicators for neonatal hyperbilirubinemia. A clinical and laboratory study was conducted to assess the metabolic status in prolonged neonatal hyperbilirubinemia
Principles of Screening of Visual Functions in Cases of Vertebro-Basiliar Deficiency
No full textActuality. Blood circulation deficiency in the vertebrobasilar system is dangerous as it causes hypoperfusion and hypoxia in eye tissue. Despite the fact that changes in the eye caused by vertebrobasilar insufficiency have been called by different medical terms in the last 10 years, this disease is a group of pathologies that have not lost its relevance until now.
Aims and objectives: early identification of signs of changes in the eye caused by vertebrobasilar deficiency and study of specific aspects of their clinical course.
Material and methods. 20 patients of the first group, who were treated in the inpatient department of the Central Hospital of the Ministry of Internal Affairs of the Republic of Uzbekistan, underwent surgery to eliminate VBS blood circulation insufficiency (international classification of diseases (ICD) -10; G45.0), while 20 patients of the second group were treated conservatively, and their The analysis results of neurovisual and neurophysiological examination methods were compared.
Results and discussion. Visual acuity recovery was 1.3 times higher in the first group than in the second group. These results were explained by the rapid recovery of hemodynamics, which were also reflected in the results of the computer perimetry study. In the second group, the average values of RNFL thickness were higher (169.5±14.8 μm), temple (105.4±7.8 μm), lower (191.4±15.0 μm) and nose (90.15±6, 47 μm) in the quadrant decreased compared to the first group. A statistically significant difference was found in the RNFL thickness of the upper (p<0.05), temporal (p<0.05) and lower (p<0.05) quadrants compared to the first group.
Conclusions. The detection of scotomas in perimetry, which are not part of the defects detected during the OCT of the RNFL, indicates the presence of pathologies in the internal carotid artery in the chiasm, optic tract, or postgenicular optic tract. In such cases, it is appropriate to appoint patients to undergo MRI, and in cases where there are no changes in MRI, functional radiological examinations
New Morphological Ideas of the Participation of the Thymus Gland in the Processes of Immunity
No full textThe thymus (thymus gland) is the central organ of T-lymphocytopoesis, the formation of T-lymphocyte progenitor cells and a number of thymic hormones takes place in it. Structural and functional rearrangements of the thymus under the influence of the temperature factor are characterized by cyclicity, where periods of early changes, peak and distant changes are distinguished. Each of the periods is characterized by its own characteristics, which determine the essence of adaptive organ rearrangements in response to temperature exposure.
 
Primary and Secondary Hyperalgesia
No full textAccording to the definition of the International Association for the Study of Pain, hyperalgesia means "an excessive reaction to moderate nociceptive stimulation". Primary hyperalgesia or peripheral sensitization is a reflection of activation and sensitization of nociceptive A-delta fibers and terminal windows of polymodal C-fibers in injured tissues. The basis of secondary hyperalgesia or central sensitization is spinal neuroplasticity and facilitating the transfer of nociceptive information to supraspinal structures
Modern Aspects of Dysmetabolic Nephropathies in Children
No full textThe review article is devoted to the study of etiological factors and pathogenetic mechanisms in dysmetabolic nephropathies in children. New studies on the informative value of cystatin C and metabolic aspects of the formation of renal pathology in children are presented. The authors have generalized and systematized modern domestic and foreign data
Modern Methods of Early Diagnosis of Inflammatory Periodontal Diseases
No full textThe development of scientific and technological progress has made it commonplace in the clinical practice of a periodontist to use often technically rather complex and expensive paraclinical methods, which, with a certain degree of conventionality, can be divided into radiological, laboratory and functional
Body Temperature Increase and Resulting From Febrival Convulsions
No full textFebrile seizures, commonly in children between the ages of 3 months to 5 years, are a neurological abnormality characterized by neuronal hyper-excitability, that occur as a result of an increased core body temperature during a fever, which was caused by an underlying systemic infection. Such infections cause the immune system to elicit an inflammatory response resulting in the release of cytokines from macrophages. This article provides information about febrile convulsions caused by an increase in body temperature
PATHOMORPHOLOGICAL CHANGES IN PROTRUSIONS AND CIRCULAR VERTEBRES
No full textThe article discusses Schmorl's hernia and its effect on the properties of the spinal canal, among the changes that can occur with degenerative diseases of the lumbar spine. Based on a pathomorphological study, changes in the spinal cord, discs and spinal cord caused by Schmorl's hernia were studied in 26 patients with degenerative diseases of the spine
Use of ACTH and Prednisolone with Infantile Spasms: The Experience of the Country of Uzbekistan
No full textInfantile spasms (IS; West syndrome) is a severe form of epilepsy, a characteristic EEG appearance called hypsarrhythmia, and a high risk of severe developmental delay are other features of the syndrome. Seizures usually begin in the first year of life, often between 3 and 8 months of age. Seizures are difficult to treat, and the long-term outcome for seizure control and child development remains poor. Due to low response rates worldwide, a wide range of drugs are being used to treat IS. However, the two commonly used forms of therapy are adrenocorticotropic hormone (ACTH) and prednisone (or prednisone) for the treatment of infantile spasms (IS) in West syndrome. Potentially key early contacts for families are pediatric neurologists, pediatricians, and other pediatric healthcare professionals who have I have a child with West Syndrome. In many countries, ACTH is expensive and difficult to obtain, while the drug prednisone or prednisone is cheap, taken orally and readily available