Scholastic: Journal of Natural and Medical Education
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ARTERIAL HYPERTENSION IN PATIENTS WITH COVID-19
No full textThe COVID-19 pandemic has caused unprecedented morbidity, mortality and global social unrest. Considering the high prevalence of arterial hypertension (AH), as well as the fact that components of the renin-angiotensin-aldosterone system (RAAS) are interested in the penetration of the virus into the body during the coronavirus pandemic, further study of the features of the course of arterial hypertension in survivors of COVID-19. The study was conducted on the basis of the cardiology department of the multidisciplinary clinic of the Tashkent Medical Academy. Hypertensive patients with covid-19 had statistically significant (p=0.031) blood pressure instability compared with hypertensive patients without covid-19 (35.0% vs. 25.0%)
Myopia and Some of its Complications
No full textThis review article examines modern views on etiological factors and the pathogenesis of complications associated with myopic refraction. Domestic and foreign studies aimed at identifying the mechanisms of development of this pathology using modern diagnostic methods are analyzed. Also summarized is the literature data that myopia is characterized not only by changes in refraction and the relationship of the anatomical structures of the eye, but also by a number of pathological processes associated with impaired hemodynamics and hydrodynamics of the eye
Evaluation of Clinical Presentations of Covid -19 in Pediatric Patients in the Child Central Teaching Hospital
No full textBackground: The coronavirus belongs to a family of viruses that may cause various symptoms such as pneumonia, fever and breathing difficulty. These viruses are common in animals worldwide, but very few cases have been known to affect humans.
AIM of the study: To increase the awareness of different patterns of symptoms and signs of covid -19 in children.
Methods: this is prospective study of patients those admitted to the child central teaching hospital and confirmed covid 19 infection by real time polymerase chain reaction from twentieth of march 2020 to the first of April 2021. patients sex, age, symptoms, signs, duration of the symptoms before the admission to the hospital crowdedness, their status of vaccination in particular BCG vaccine, Investigations (white cell count, chest Xray) and the fate of those patients. Patients with chronic diseases also included. The study group had a postive contact with confirmed covid-19 relatives that either living with them or had visited them.
Results: one handered twenty patients with confirmed covid-19 infection admitted to (central teaching hospital for pediatrics) during the study period, noticed that there was 58 male (48%) and 62 females (52%), patients had different age groups, most affected age group was 1-5 years 34 patient (28%) and 5-10 years (28%) also. The most common signs and symptoms were fever 78 patient (65%), malaise 50 patient (41%), Cough 45 patient (37%), dyspnea 37 patient (30%) and frequent bowel motion 38 patient (31%). Sign and symptom found to be significantly related to either death or admission to the respiratory care unit like cyanosis (4.2% p-value 0.0001), Fever (65% p-value 0.03), disturbed level of consciousness (2.5% p-value 0.035), frequent bowel motion (31.7% p-value 0.045). Ten patients (8%) needed respiratory support, About two third of patient (62%) lives in a crowded environment and (62.5%) reported that they had contacts with confirmed COVID 19 infected patients. Twenty nine patient (24.2%) those with COVID-19 virus infection had comorbid conditions. The result of chest Xray of 63 patient (52.2%) with ground glass appearance, Consolidation was found to be the most related chest x-ray finding related to death and respiratory care unit admission about (14.2% p-value 0.0001). There were two peaks of signs and symptoms like (fever, malaise and vomiting) during the summer months especially August followed by a higher peak in the winter months especially January. Frequent bowel motion peak was in the winter months especially January and February.
Conclusion: The infection had two peaks during the year. Females slightly more than males. Fever, malaise, cough, shortness of breath and frequent bowel motion were the prevalent symptoms. duration of the occurance of the signs and the symptoms mainly 3 days. About two thirds live in crowded areas and with contact to infected patient. The children have mild symptoms with highly recovery rate. Only minority of patients was admitted to respiratory care unit for ventilatory support
Psychological Disorders In Iraqi Women With Cervical Cancer Through A Cross-Sectional Study Of 120 Patients
No full textBackground: Psychological disorders affect the decline in the quality of health life in the treatment of cervical cancer patients. Objective: This study was contributed to assess the quality of life for patients with cervical cancer and psychological disorders. Patients and methods: A cross-sectional study was conducted for female patients (120) with cervical cancer who suffer from psychological disorders, aged between (35-50) years, for the period from February 15th, 2022, to July 9th, 2023, in different hospitals in Iraq. A prospective evaluation was performed to investigate the survival rate of patients with mental disorder-associated cervical cancer within five years. Results: This study identified the factors that contribute to psychological and mental illnesses brought on by cervical cancer. Of them, psychotic disorders account for 34 individuals, depressive disorders for 30, and anxiety disorders for 15. Examined were the quality-of-life scores of the patients, which documented functional, social, and physical aspects. The majority of women who presented with mental problems-maintained survival rates, with the lowest being 70% and the greatest being 96%, according to this study's evaluation of patient survival rates. Conclusion: Psychological illnesses have a detrimental impact on health quality rates and are linked to the short survival rate of patients with cervical cancer
An Integrated Approach to Diagnosis and Treatment of Allergic Rhinitis
No full textA study was conducted on 40 patients aged 18 to 60 years who were diagnosed with allergic rhinitis. As part of the study, allergy histories were collected, objective data were obtained, an endoscopic examination of the nasal cavity was performed, as well as cytological and bacteriological examination of smears from the nose and nasopharynx. The patients received complex treatment for allergic rhinitis, including elimination, hyposensitizing, immune, antifungal and local therapy, as well as surgery for resection of the nasal septum with vasotomy of the inferior turbinates. As a result, pronounced positive effects were obtained in 73.7% of patients, an insignificant effect in 22.8%, and 3.5% of patients did not receive a positive effect from the treatment
Association of С-344Т Gene Polymorphism with Adrenal Incidentaloma in Uzbek Population
No full textThe objective of the given research was to study distribution of С-344Т polymorph marker of CYP11B2 gene and possible relation of that polymorphism to hormonal, biochemical, and multifunctional parameters of testing in patients with adrenal incidentalomas. We have checked 80 Uzbek patients with adrenal incidentalomas, who received out and inpatient therapy and were followed at the clinic of Turakulov RSSPMC of endocrinology. Verification of the diagnosis of adrenal incidentaloma was based on clinical biochemical, hormonal, and visual imaging tests. Eighty samples of whole blood were genotyped for С-344Т polymorphism of CYP11B2 gene. Analysis of the obtained results showed dominance of СТ-heterozygotes on С-344Т polymorph marker of CYP11B2 gene in Uzbek people suffering adrenal incidentaloma. Analysis of the associations of CYP11B2 gene polymorph markers carriage with parameters of hormonal status, electrolyte balance, and blood lipid spectrum revealed several peculiarities. Carriage of СТ- and ТТ-genotypes of CYP11B2 gene С-344Т polymorph marker is associated with higher levels of aldosterone in blood serum of the patients with adrenal incidentalomas, whilst ТТ-homozygotes had reliably lower values of potassium and high level of sodium in blood serum; carriage of СТ-genotype of CYP11B2 gene is associated with the risk of GTI in patients with adrenal incidentalomas. Analysis of correlations between AP parameters and hormonal status showed low-renin character of arterial hypertension associated with CYP11B2 gene С-344Т polymorph marker T-allele carriage
Clinical Features of Otitis Media in Patients with Hiv Infection
No full textThe work was carried out at the clinical base of the Bukhara State Medical Institute - and at the regional multidisciplinary clinical hospital. Analyzed data of examination and treatment of 75 patients from 18 to 60 years old, with ENT pathology against the background of HIV infection for the period from 2020-2021. Also examined were 30 non-HIV-infected patients of the same age and sex. All patients underwent a comprehensive examination, including otorhinolaryngological, clinical laboratory, bacteriological, and immunological studies.
HIV-infected patients are characterized by frequent exacerbations of ENT diseases, in which 78.8% of patients were hospitalized due to the severity of the disease, and 21.2% of patients were treated in an outpatient setting. Severe and complicated forms of ENT disease occurred at a high frequency against the background of HIV infection, accounting for 23%. Of the complications that developed against the background of HIV infection, 13.4% were meningitis, 7.7% were brain abscesses, 1.9% were severe sepsis, and 9.6% were fatal
Effectiveness of Mininvasive Laparoscopic Cholecystectomy when Stony Cholecystitis is Complicated by Mechanical Jaundice
No full textCholecystectomy is especially one of the laparoscopic treatments that many surgical assistants firstly learn and apply. The validity of laparoscopic cholecystectomy (LC) is today indisputable in symptomatic gallbladder stones, other benign gallbladder diseases and early stage malignancy according to certain authors. It is already the most common and widely applied laparoscopic intervention today. Between 20 and 40% of patients with gallstones will develop gallstone-related complications, with an incidence of 1–3% annually; calculus cholecystitis (CC) is the first clinical presentation in 10–15% of the cases
Oncopsychology of Patients with Breast Cancer after Treatment
No full textRehabilitation of a patient with cancer includes not only physical recovery and restoration of the functioning of the body, but also the maximum possible return to normal life before the disease. This is unattainable without taking into account the personality of the sick person. The success and high probability of a favorable outcome in the treatment of oncological diseases significantly contributes to an increase in the life expectancy of patients with malignant neoplasms of the breast, according to studies, five-year survival rates exceed 80% compared to the past decade
Intestinal Parasitic Infections in Beta Thalassemia Major and Aplastic Anemia in Diwaniyah Province
No full textBeta- thalassemia major (B-TM) and aplastic anemia are among the most complex chronic diseases because they are associated with serious complications as microbial infections. Current study aimed to isolation Intestinal parasite and evaluation their role in B-TM and Aplastic Anemia complications in Diwaniyah Province. Methods: This study included 50 children with B-TM and 53 children with aplastic anemia, we confirmed the clinical examinations by Lab diagnosis in Thalassemia Center, and the Maternity and Children Teaching Hospital. Lab diagnosis included; Complete blood count and blood film method, Hemoglobin electrophoresis, Reticulocyte count, iron test, blood groups and general stool examination. Results: The current study included 50 children B-TM their ages ranged from 2 to 11 years, with an average age of 4.13 years and 53 children suffering from aplastic anemia, their ages ranged from 2 to 12 years, with age mean is 6.22 years. The results of the isolation and diagnosis of intestinal parasites showed that 70% of thalassemia patients suffer from intestinal parasitic infections represented by Entamoeba histolytica, Giardia lamblia, Blastocystis hominis, Ascaris lumbricoide, Ancylostoma duodenale and Strongyloides stercoralis by percentage 14%, 37%, 14%, 20% and 9% and 6% respectively. We also found that 62% of anemic patients suffered from intestinal parasitic infections that included Entamoeba histolytica, Giardia lamblia, Blastocystis hominis, Ascaris lumbricoide, Ancylostoma duodenale and Strongyloides stercoralis in rate 6%, 15%, 18%, 30%, 6% and 24% respectively. In conclusion: Intestinal parasites pose a significant risk of B-TM and aplastic anemia patients