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    2915 research outputs found

    Modern Ideas about the Cause and Development of Tuberculosis

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    Modern science views tuberculosis as a multifactorial disease in which environmental factors closely interact with the human genome and the pathogen Drug-resistant tuberculosis complicates the treatment of patients with resistant strains of tuberculosis and threatens the global process to achieve the goals set by WHO in the Strategy to End Tuberculosis in the World

    Rehabilitation of Patients after Ischemic Stroke Using Transcranial Direct Current Stimulation

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    45 patients in the acute period of ischemic stroke, aged 39–71 years were examined. All patients underwent: a study of neurological and somatic status, with verification of neurological deficit according to the NIHSS scale , to assess impairment of consciousness and coma, the Glasgow scale, to assess the degree of motor and daily activity using the Rankin and Barthel scale , to assess the recovery of motor deficit after a stroke, the APAT test was used . The use of TES in patients with stroke, regardless of the electrode application area, improves cognitive functions in naming objects, performing speech functions, which is accompanied by an increase in patients' motivation for rehabilitation and treatment and is reflected in an improvement in their quality of life

    Clinical Manifestations of Cardiotoxicity in Acute Leukemia and Methods for their Examination

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    Currently, more and more attention is paid to cardiotoxicity, which develops against the background of anticancer treatment. Achievements of modern oncology are associated with the use of effective combinations of chemotherapeutic drugs and radiation therapy, at the same time, some of the commonly used drugs, as well as radiation therapy in some patients, leads to the development of various complications

    The Concept of Ectopic Pregnancy Observed in Women

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    Ectopic pregnancy is the most common pathology in gynecologic practice, leading to the reduction and loss of reproductive function. Diagnosis of ectopic pregnancy in cases of its occurrence interrupts and intra-abdominal bleeding does not provide significant difficulties. Of interest is the search for ectopic gestational sac located in rare forms of ectopic pregnancy. Although progress has been made in the diagnosis and treatment of ectopic pregnancy is not possible to achieve reduction of complications associated with it

    Improvement of the Method of Treatment and Prevention of Anastomositois after Surgical Interventions on the Stomach and Duodenum

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    Gastric ulcer (GU) and duodenal ulcer (duodenal ulcer) is one of the most common pathologies in all regions of the world (Chaika A.V., 2018; Ruchkin D.V., 2019). At the same time, the prevalence of this pathology increases with increasing age (Chernousov A.F., 2016). In absolute terms, annually PU affects 4 million people worldwide, while complicated forms of the disease develop in 10-20% of patients (ThorsenK., 2013; Hasselager R.B., 2016)

    Management and Epidemiology of the Appendicitis in Patients

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    Acute appendicitis is one of a relatively dwindling number of conditions in which a decision to operate may be based solely on clinical findings. Laparoscopic appendicectomy is becoming the gold standard of treatment but non-operative management with antibiotics may suffice in selected cases with uncomplicated appendicitis. The advantages of the innovations in minimally invasive and endoscopic surgery are unlikely to render formal open appendicectomy obsolete. The controversy in the management of the appendix mass/abscess remains

    Risk Factors for Breast Cancer

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    Breast cancer occupies a leading place among malignant neoplasms in women in all economically developed countries Breast cancer is a serious medical and social problem for most developed countries of the world. Analysis of the qualitative characteristics of diagnosis, staging and treatment of breast cancer will routinely confirm the achievability of reducing the risk of cancer recurrence with an appropriate standard of treatment

    Pathogenic Influence of Pesticides on the Thyroid Gland of Offspring under the Conditions of Their Exposure through the Mother's Body during Pregnancy and Lactation

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    The aim of the study was to identify the toxic effect of intrauterine and early postnatal exposure to pesticides on the development of the endocrine system of offspring. The thyroid gland of the offspring obtained from mothers with chronic poisoning with pesticides vigor and fastkine was examined on 1-30 days after birth using electron microscopic methods. It was revealed that intoxication of the mother's body significantly slows down the pace of postnatal formation of secretory follicles. Ultrastructural changes were found in the form of disorganization of the granular endoplasmic network and destruction of other cytoplasmic organelles of thyrocytes. These changes are a morphological substrate of thyroid dysfunction that occurs in the postnatal ontogenesis of the organ in conditions of chronic intoxication. Toxic effects of pesticides on the endocrine systems of offspring under the conditions of their exposure through the mother's body during pregnancy and lactation The thyroid gland of posterity, got from full-grown with chronic intoxication by pesticides vigor and fastokine, has been studied on 1-30 day after birth using electron microscopy methods. It is revealed that intoxication of maternal organism vastly slows the rates of postnatal formation of secretory follicles. It is expected that discovered ultrastructural changes of the thyrocytes are morphological substratum of the dysfunctions of the thyroid gland

    Risk Factors for Tooth-Jaw Disorders in Children

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    The only reason for their development for the appearance of tooth anomaly and deformities cannot be Endo - or exogenous factors, which indicates the multifactorial basis of the disease. It is important to note that some of the identified risk factors are integrative in nature and are the result of a combination of many previous causes

    The Development of a Systemic Inflammatory Reaction Syndrome, the Development of Inflammatory Complications, Multiple Organ Failure and Death in Patients with Acetic Acid Poisoning

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    Relevance. It is also important that VPD poisoning is characterized by severe medical, social and economic consequences such as: costly treatment, prolonged disability, disability, high mortality. Poisoning with toxicants of cauterizing action is characterized by high lethality. This is especially true of acetic acid, which averaged 11.7%, respectively, reaching 30.6% in a number of hospitals, and among the deaths caused by caustic poisons, acetic acid was 72.0%. The toxicity of acetic acid is directly proportional to its concentration in the body. 30-70% solution, called acetic essence in everyday life, causes severe chemical burns

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