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Патогенетическая Значимость Нарушения Баланса Цитокинов В Изучении Особенностей Развития И Течения Недифференцированного Артрита На Этапах Развития Ревматоидного Артрита
Full text linkНа сегодняшний день ревматоидный артрит (РА) - одно из самых распространенных хронических ревматологических заболеваний в мире. РА взаимодействуя с факторами внешней среды и генетической предрасположенностью, проходит несколько стадий эволюции — доклиническую и клиническую, завершающиеся формированием клинико-лабораторного симптомокомплекса, характерного для раннего (НДА), а затем развернутого РА. В настоящее время важная роль в патогенезе РА отводится нарушению баланса уровней провоспалительных цитокинов. Целью нашего исследования являлась оценка значимости уровней провоспалительных цитокинов (IL-1β, IL -6,IL-17 и TNF-α) при раннем РА (НДА) и развернутом РА. Было обследовано 103 пациента (больные РА-53 и больные НДА-50). Обследование больных включало оценку клинических и лабораторных параметров, таких как: оценка активности заболевания по индексу DAS 28, уровни СОЭ, СРБ, IgM РФ, АЦЦП и исследование цитокинов (IL-1β, IL -6, IL-17 и TNF-α). Показано, что при РА была выявлена положительная корреляция сывороточных уровней цитокинов IL-1β, IL-6 с индексом DAS 28, а также отмечена корреляция IL-1β, IL-6, TNF-α с уровнем IgM РФ и IL-1β с уровнем АЦЦП. Так же, в данной группе наблюдалась корреляция между IL-1β, IL-6, TNF-α и суровнем СРБ. Но не наблюдалась корреляция между уровнем цитокина IL-17 и клинико-лабораторными показателями. При НДА была отмечена положительная корреляция между IL-1β, IL-6, IL-17 и IgM РФ; IL-1β, IL-6 с АЦЦП. Не была отмечена корреляция между TNF-α и с клинико-лабораторными показателями. Также, при НДА не наблюдалась корреляция цитокинов с индексом DAS 28 и уровнем СРБ. Таким образом, результаты нашего исследования свидетельствует о связи провоспалительных цитокинов между клинико-лабораторными показателями, играющими фундоментальную роль в иммунопатогенезе РА и НДА
Enhancing Preschool Language Acquisition: the Efficacy of Interactive Methods in Teaching Russian Language to Preschool Children
Full text linkThis scientific article explores the use of interactive methods in teaching the Russian language to preschool children, with a focus on fostering effective language acquisition and communication skills. The study delves into the significance of early language education and the role that interactive methods play in engaging young learners. Drawing on pedagogical theories and empirical evidence, the article provides insights into the benefits, challenges, and best practices associated with implementing interactive teaching approaches in the context of preschool Russian language education
Factors Associated with Compliance with Repeat Visits in 1-Month Birth Control Acceptors at PMB G
Full text linkFamily planning is an effort to regulate the birth of children, the ideal birth distance and age, regulate pregnancy, protection and assistance in accordance with reproductive rights to create a quality family. Acceptor compliance with injectable contraceptive visits is very important so that the goal of contraceptive use can be achieved, preventing unwanted pregnancies. Decreasing birth control visits or family planning participation will result in a high risk of pregnancy. Objective: To find out the factors related to compliance with repeat visits in 1-month contraceptive injection acceptors at PMB G. This research is a quantitative study with a cross-sectional design method. The population is 90 people receiving 1-month injectable contraceptives and a sample of 30 people using total sampling technique. The majority of respondents had good knowledge, 15 people (50%), 18 people (60%) who were supported by their husbands, and 19 people (63%) who complied with the 1-month injection re-visit. There is a relationship between knowledge and compliance with 1-month injection return visits with a p-value of 0.01, and there is a relationship between husband's support and compliance with 1-month injection return visits with a p-value of 0.01. There is a relationship between factors, which is knowledge and the husband's support for compliance with the 1-month KB injection visit at PMB G. It is hoped that this can help as input for health workers to pay more attention and remind acceptors to make timely return visits
Descriptive Analysis of Savings and Growth in Nigeria Economy
Full text linkThis study aims at providing qualitative analysis of the relationship between domestic savings and economic growth in Nigeria. This study employed annual secondary data obtained from World Data Indicator (WDI), World Bank publication and Statistical Bulletin of the Central Bank of Nigeria for the period of 1970 to 2006. Descriptive Statistics were used.
This study therefore concludes that the problem with Nigeria’s economy is not that of mobilizing domestic savings but that of intermediation and thus recommends that government should adopt policy enhancing intermediation between savings and investment in the economy by providing regulating and coordinating role to ensure effective intermediation between savings and growth in the economy
Examining Complications and Success Rates of Laser Fistula Surgery: An Evidence-Based Approach
Full text linkThe study investigates the effectiveness of laser fistula removal surgery by analyzing its complications and success rates. Despite being a common procedure, there remains a knowledge gap regarding its comprehensive clinical outcomes. A cross-sectional study was conducted on 93 patients who underwent this surgery in various hospitals in Iraq from April 2022 to August 2023. Data on operative times, complications, recovery, and patient satisfaction were collected and analyzed. The findings revealed that the procedure had a high success rate of 90.32%, with minimal complications such as infections (6.45%) and recurrences (2.15%). These results imply that laser fistula removal surgery is a highly effective and safe treatment option that significantly enhances patients' postoperative quality of life and satisfaction, suggesting its broader application in clinical practice
Sulayman Al-Bassam’s Adaptation of Shakespeare’s Richard III: A Politico-Cultural Analysis
Full text linkBorn in 1972, Sulayman Al-Bassam is a renowned Kuwaiti-Britain dramatist and theatre director whose vigorous style and diction shape the contours of his plays. He founded Zaoum Theatre in London in 1996 and is well-known for his drama entitled The Arab Shakespeare Trilogy, which includes three plays that adapt Shakespeare's works to the context of the Arab world: The Al-Hamlet Summit, Richard III: An Arab Tragedy and The Speaker's Progress. Being a Kuwaiti playwright is undoubtedly exciting, particularly when bringing a Shakespearean drama that launches the themes of tyranny and invasion to Middle Eastern audiences. By so doing, Al-Bassam manages to intertextualize Shakespeare’s plays, modifying and redirecting the context to the Arab world. The current study, however, examines Al-Bassam's adaptation of Shakespeare’s Richard III, which has strong political connotations and discursivity. The study is divided into two sections and a conclusion. The first section provides an overview of Al-Bassam's literary and socio-political backgrounds as well as Shakespeare’s original version of Richard III. On the other hand, the second section sheds light on the intertextuality theory and its application to the chosen play. Furthermore, the conclusion sums up the findings of the study
Using Geospatial Technologies to Separate Soil Units and Predict Some of Their Characteristics in Basra Governorate (Indices)
Full text linkThis study was conducted to classify the soils of eastern Basra Governorate, southern Iraq, within the administrative borders of Abu Al-Khasib District extending south to Al-Faw District, using remote sensing techniques and geographic information systems. The soil units were separated by adopting remote sensing technology through the use of satellite image from Landsat8, the TIRS - OLI sensor (The Operational Land Imager), and spectral indices with field observations. A map of the soil units was prepared using the GIS program. Eight locations of soil pedons were identified, and they were divided The study area is divided into two paths, and each path contains four typical pedons within the boundaries of the study area as follows:
1 - First stripe: represents the river levees unit within pedons 1, 3, 5 and 7.
2 - Second stripe: represents the river basin unit within pedons 2, 4, 6 and 8.
The results of Indices showed a variation in their values between all the pedons through which spatial variation in surface soil characteristics can be distinguished. The values of NDVI ranged between < 0 – 0.79, < 0 – 1.64 for BSI, and between < 0 – 0.408 for SAVI. The spectral indices NDVI and SAVI gave results that match the ground facts present on the ground, represented by vegetation, while the bare soil index BSI gave reflectivity values similar to barren lands. The lands of the study area were characterized by a lack of vegetation, especially in the low-lying areas of the river plains, while the areas of natural vegetation and the parts close to the river levees were characterized by a medium to high vegetation cover, and these results are consistent with the values of the NDVI and SAVI spectral indices
Ground Water Quality Assessment Using the Water Quality Index, Iraq
Full text linkWater Quality Index (WQI) has been applying in the present study to assess suitability of groundwater quality for drinking purposes in Amara city, southern Iraq. This was carried out by subjecting twelve groundwater samples, collected from different sites to comprehensive physic-chemical analysis. Ten parameters have been considered for calculating the WQI such as; pH, electrical conductivity, total dissolved solids, sodium, potassium, calcium, magnesium, chloride, sulphate and nitrate. The WQI values shows that 16.66% of water samples falls in good water categories and the others (83.66%) ranged from poor water to unsuitable for drinking purposes under normal conditions and further action for salinity control is required. The high value of WQI at this study has been found to be mainly due to the higher values of EC, TDS, SO4-2, Ca+2, Mg+2 and Cl- where it was found that there is a very high correlation coefficient between them
Natural Distribution and Medicinal Properties of the Ferula L Genus Growing in Mountainous and Desert Areas in Uzbekistan
Full text linkThis article presents literature data on the natural distribution and medicinal properties of Ferula L, which grows in Uzbekistan in mountainous and desert regions
Optimum Seedling Thickness of Soybean Varieties of Different Planting Methods and Tillage between Rows
Full text linkAs a result of cultivation of "Nafis" and "Selekta 201" varieties of soybeans in the 60x8x2 scheme, 16-18 cm deep between the rows and 18-20 cm deep between the rows in the 70x8x2 scheme, the optimal seedling thickness is determined to be 320-334 and 361-379 plants per hectare, improving the water permeability of the soil, it was found that the porosity, volume mass and the amount of humus in the driving and sub-driving layers were improved