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Features of the Clinical Course of Dementia Due to Epilepsy
Get PDFEpilepsy is a chronic neurological disease that manifests itself in the predisposition of the body to the sudden onset of seizures. The onset of a single seizure characteristic of epilepsy is possible due to the specific reaction of a living organism to the processes that have occurred in it. According to modern concepts, epilepsy is a heterogeneous group of diseases, the clinic of chronic cases of which is characterized by convulsive recurrent seizures. The pathogenesis of this disease is based on paroxysmal discharges in the neurons of the brain.
Apoptosis of Cardiomyosites in Heart Disease
Get PDFAlthough the notion that apoptosis can act as a pathogenic mediator came somewhat later to car-diovascular medicine than to other fields of medicine, research into the role of apoptosis in heart disease has progressed explosively during the past 10 years. Consequently, we now have much information about apoptosis in cardiac cells, collected in vitro and in vivo under a wide variety of pathological conditions using both experimental animal models and specimens from heart disease patients, and there are a number of excellent reviews dealing with the role of apopto-sis in heart disease [1–11].
Among the various cardiovascular ailments, myocardial infarction (MI) is particularly note-worthy for having high rates of both mortality and morbidity. Patients experiencing MI are at risk of sudden death during the acute stage and then ven-tricular remodeling and heart failure during the chronic stage, with the most critical determinant of the remodeling being the magnitude of the acute infarct (i.e., the number of dead cardiomy-ocytes resulting from the acute ischemic insult). In addition, other factors, including late death or hypertrophy of cardiomyocytes, fibrosis and the expression of various cytokines, are associated with the continued disease progression during the chronic stage. Notably, apoptosis has been detect-ed in the heart during all stages of MI, suggesting apoptosis may be responsible for a significant amount of cardiomyocyte death during the acute ischemic stage, as well as for a progressive loss of surviving cells during the subacute and chronic stages. Patients who survive large MIs are at espe-cially high risk of developing such failure. Indeed, patients with post-infarct heart failure account for 44% of candidates for cardiac trans-plantation [12].
Heart failure is the final outcome of a number of heart diseases. Although the mechanisms for cardiac decompensation have not been fully elu-cidated, loss of cardiac myocytes has been con-sidered important as well as dysfunction of indi-vidual cardiac myocytes for one of the mecha-nisms. Extensive study now indicates that apopto-sis is deeply involved in the pathology of almost all types of heart disease, not only ischemia-relat-ed ailments (ischemia-reperfusion, the acute and chronic stages of MI, ischemic cardiomyopathy and hibernating myocardium), but also other heart diseases such as dilated cardiomyopathy. Thus, apoptosis appears to be established as one impor-tant mode of cardiomyocyte death that is respon-sible for the development and worsening of heart failure. Other than ischemic hearts and failing hearts, cardiac arrhythmias is an important dis-ease entity where apoptosis is suggested to play a role in the pathogenesis [13–16]
Dynamics of Indicators Characterizing the Clinical Condition of the Oral Mucosa
Get PDFRelevance. The examination of patients and the registration of indicators were carried out strictly in accordance with the recommendations described in the chapter "Materials and methods of research" on the 7th, 14th day and a month after the application. The clinical criteria for the effectiveness of treatment were: the dynamics of the general condition (subjective and objective indicators), the timing of epithelialization of lesions and the results of biochemical and hematological studies
Innate and Adaptive Immunity in Patients with Chronic Kidney Disease
Get PDFChronic kidney disease (CKD) is defined as a supranosological concept characterized by structural damage to the kidneys and/or a decrease in their function for 3 months or more, regardless of the nosological diagnosis of chronic renal disease [18, 30
Reactivity of Rozhinets in Mild Iron Deficiency Anemia
Get PDFThe article is devoted to an urgent problem – violations of labor activity of women in labor, against the background of changes in vegetative reactivity with iron deficiency anemia of moderate severity. The object of the study was 30 women in labor with iron deficiency anemia of moderate severity. At the same time, in women in labor with a moderate predominance in the reactivity of the autonomic nervous system of the tone of the sympathetic nervous system, the reserve force of adaptation decreases to 22.2%, that is, 77.8% of the reserve power, and women in labor with pronounced sympathetic reactivity: the reserve force of adaptation decreases to 24.6% and has 75.4% of the reserve In women in labor with a predominance of parasympathetic reactivity, the reserve force of adaptation is increased up to 26% and has 126% reserve capacity
Ultrasound Examination as an Important Part of Clinical Diagnostics
Get PDFUltrasonography has advantages over other imaging modalities in terms of availability and comfort, safety, and diagnostic potential. Recent advances of clinical diagnosis are largely determined by the improvement of research methods. Significant leap in this regard was made by the development and introduction of fundamentally new ways of medical imaging, including ultrasound method. Extremely valuable is the ability of ultrasound to visualize the internal structure of the solid organ that was not available in the traditional X-ray. Due to the high information content and reliability of the ultrasonic method of diagnosis of many diseases and injuries has risen to a new level. The author has carried out an analysis of numerous literary sourcaes and concluded that ultrasound has a high diagnostic capability and prognostic value of advanced new technologies in the diagnosis of various pathologies. Ultrasonography using a high-resolution technology in the clinic allows us to differentiate the severity of the pathological process, determine its dynamics and reliably monitor the effectiveness of treatment
Conceptual Study on Trividha Karma in Ayurveda
Get PDFFor a surgical or parasurgical procedure to be done successfully, it is highly intended and essential to follow all standard protocols suggested by various acharyas through different samhitas. In case of surgical branches while performing any shastra, kshar or agni karma it is mandatory to prepare well in advance so that there won’t be any troubles in Pradhan karma or main operative procedures as well for better outcomes and no complications. Acharya sushruta was well known to this fact in that era too, so he emphasized on Trividha karma viz Purva karma, Pradhan karma and Pashchat karma. Here purva karma refers to the pre-operative preparation of patient along with collection of tools, accessories and make OT ready to operate in which main task has to be done i.e Pradhan karma which includes ashtavidhashastra karma. And pashchat karma includes post-operative care of patient. It is necessary to follow this trividh karma for better results and outcome in surgery. That is why it has got tremendous importance in surgery since ancient times
Study Effect of Fibrinogen on Patients with Cardiovascular Disease
Get PDFCardio vascular disease has become a great problem throughout the world. It is connected to increase morbidity and mobility and decrease quality of life in patients compared to the general population. many cases of disease has been described in cardiovascular disease. The study conducted on too Iraqi patient with chronic atherosclerosis at age rang (29-70years) in Baquba teaching hospital in (center care unit) during the period from 25 September 2020to may 2021. The patients divided in (55 mans and 45 patients) the total patient divided in tow groups according the treatment (30) of total patient under go to treatment for two to three days after atherosclerosis and 70 patient in same day of diagnosis of atherosclerosis. Fibrinogen value increase and we can use this as biomarkers with Atherosclerosis
Prevention of Complications in the Postoperative Period when Treating Ventral Hernia
Get PDFThe use of synthetic materials for hernial orifice repair in patients with postoperative ventral hernias (POVH) has reduced the incidence of wound complications. However, the success of surgical treatment of patients with POVH largely depends on complete preparation for surgery, the choice of the optimal method of alloplasty and rational management of the patient in the postoperative period. An analysis of the results of surgical treatment of 143 patients with POVH for the period 2018-2022, operated on at the regional multidisciplinary medical center (RMMC), was carried out. For plastic surgery of the hernial orifice, a polypropylene mesh implant “Paha” (Turkey) was used. In 65 (45.4%) patients, supraponeurotic (on1au) plastic surgery was performed, and in 78 (54.5%), sublay type plastic surgery was used. In the early postoperative period, general complications occurred in 7 (4.8%) patients, wound complications - in 15 (10.5%) patients, mortality was 0.69%. To improve the results of surgical treatment of patients with POVH, a number of recommendations should be followed. In the preoperative period, it is useful to conduct a comprehensive examination of patients with the development of an individual program for the prevention of wound, thromboembolic and pulmonary complications
Study Effect of Iron in Patient with Heart Disease
Get PDFThe study conducted on too Iraqi patient with chronic atherosclerosis at age rang (29-70years) in Baquba teaching hospital in (center care unit) during the period from 25 September 2020to may 2021. The patients divided in (55 mans and 45 patients ) the total patient divided in tow groups according the treatment (30) of total patient under go to treatment for two to three days after atherosclerosis and 70 patient in same day of diagnosis of atherosclerosis . it is noticed Decrease in electrolytes Iron values