Asian Journal of Advances in Medical Science
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A MINI REVIEW ON NON-ANTIBIOTIC THERAPIES TO TARGET EMERGING ANTIMICROBIAL RESISTANCE DURING POST COVID ERA
Get PDFAntibiotics considered as miracle drugs and as one of the most demanding life-saving discoveries of the twentieth century have now imposed a threat to society due to its overuse and misuse. Antimicrobial resistance (AMR) is a growing global problem to which the current COVID-19 pandemic may fuel further. The high number of patients suffering from Covid-19 worldwide have been reported to suffer further from secondary microbial infections. This has become a challenge for the medical community. Hence, various non-antibiotic strategies have been sought after and their mechanisms have been evaluated to mitigate the rise of AMR. This review gives an overview of the success of the alternate methods to combat AMR
CORONAVIRUS DISEASE (COVID-19) PSYCHOLOGICAL, BEHAVIOURAL AND INTERPERSONAL IMPACTS OF INFECTIOUS DISEASE OUTBREAKS: A REVIEW
Get PDFCoronavirus COVID-19 pandemic sweeps across the world, it is causing widespread concern, fear and stress all of which are natural and normal reactions to the changing and uncertain situation that everyone finds themselves in. WHO takes the impact of the crisis on people’s mental health very seriously and is monitoring the situation together with national authorities while providing information and guidance to governments and public. The current study was carried out to indicate that COVID-19 has negative psychological, behavioural and Interpersonal problems other than mortality. A review of the studies performed in other parts of the world showed that COVID-19 has caused several psychological impacts, including increased anxiety, stress and depression. By an increase in the prevalence rate of COVID-19 and its resulted restrictions, the level of stress, depression and anxiety increases, as well; therefore, raising public awareness of the disease and providing positive psychological programs in the media aimed at controlling stress can reduce anxiety in society
THE MAIN REASONS WHY CANCER IS SO DIFFICULT TO TREATMENT
Get PDFThe “Type of Article” of this paper is “Letter to the Editor”. This paper discuses about: “THE MAIN REASONS WHY CANCER IS SO DIFFICULT TO TREATMENT”. No formal abstract is available. Readers are requested to read the full article
IMPACT AND INFECTION OF SARS-CoV-2 (COVID-19) IN INDIA: CURRENT STATUS
Get PDFCorona Virus Disease (COVID-19) is an RNA virus, and the trade impact of the epidemic for India. In humans, the transmission of SARS-CoV-2 can occur via respiratory secretions. Nosocomial transmission has been described as an important driver in the epidemiology of SARS, MERS and has also been documented in COVID-19. In India, totally were recorded (59662, and 182142), such as active cases (39834, and 89995), cured (17846, and 86983) death rates (1981, and 5164) at 10th and 30th May 2020. The case report provides an insight into the COVID-19 current situation and represents a picture of the current state of the art in terms of public health impacts
PHYTOCHEMICAL SCREENING AND COMPARATIVE GC–MS ANALYSIS OF BIOACTIVE COMPOUNDS PRESENT IN METHANOLIC LEAF AND LATEX EXTRACT Calotropis gigantea (L)
Get PDFMedicinal plants are considered as important source of promising bioactive compounds. Calotropis gigantea is a traditional medicinal plant which is known to have biochemical constituents with potential medicinal properties. Qualitative analysis showed the presence of alkaloids, terpenoids, saponins, tannins and cardiac glycosides and absence of flavonoids in ethanolic extract of C. gigantea, while the chloroform leaf extract showed absence of flavonoids and cardiac glycosides. Bioactive compounds since leaf and latex of C. gigantea utilized GC-MS and activity investigation. The GC-MS investigation uncovered the presence of complete 46 bioactive mixes (24 from leaves and 22 from latex) with significant movement. The majority of the mixes were discovered to be comparable in both leaf and latex, however little variety was likewise seen in their synthetic profile. The concoction mixes saw in just latex were 1-[(T-butyl) dimethyl silyl thin] butane, 1-Hexadecyne, Hexadecane, L-Glutamic corrosive, Phenol-3-isoproxy-5-methyl, Trocosane and Z-1,6-Tridecadiene. Mixes distinguished uniquely from the leaves were Azulene, Benalaxyl, Cis-vaccenic corrosive, Levomenol, Profenofos, β-Tocopherol and β-Sitosterol, while the remainder of the mixes were comparable in both leaf and latex. Major of bioactive compounds presents Gas Chromatography-Mass Spectroscopy (GC-MS) analysis. C. gigantea is a perennial plant abundantly found in all parts of the country (India) and wild in nature. The leaves of the plant were found to contain various primary and secondary metabolites
MEASUREMENT OF FASTING BLOOD SUGAR, SERUM TOTAL PROTEIN, SERUM ALBUMIN, SERUM TOTAL BILIRUBIN, SERUM DIRECT BILIRUBIN, AND LIVER FUNCTION PARAMETERS FOR CHILDREN WITH ACUTE LYMPHOBLASTIC LEUKEMIA
Get PDFLeukemia is a common malignancy of childhood. Leukemias are group of malignant disorders of the haematopoietic tissues that are characteristically associated with increased numbers of leucocytes in bone marrow and/or peripheral blood. The aetiology of leukemia is unknown but several lines of evidence do suggest that the disease is a result of interactions between several factors for example: viral infections, ionizing radiations, chemicals and genetic factors. The incidence of ALL varies, and depends on age, sex and race. Antineoplastic agents (cytotoxic drugs) are used in the treatment of malignant diseases when radiotherapy and surgery are not possible or they are not effective. This study aims to evaluate some of biochemical parameters in children with Acute Lymphoblastic Leukemia. The results indicated that the value of parameters tested varies according to type of test (i.e. some higher than normal, some less than normal).
Matrials & Methods: Eighteen pediatric acute lymphoblastic leukemia children were included in this study. All were subjected to γ-tocopherol, methotrexate, vincristine, and 6-mercaptopurine chemotherapy treatment. Serum fasting glucose, total bilirubin, direct bilirubin, total protein, albumin, alkaline phosphatase, alanine aminotransferase, and aspartate aminotransferase levels were measured using autoanalyser device.
Results: Of eighteen pediatric patients, two (11.11%) were hypoglycemic (22.00±1.00mg/dL), two (11.11%) with high direct bilirubin (0.50±0.00mg/dL), six (33.33%) with low total protein (3.83±0.85gm/dL), eight (44.44%) with low albumin (2.47±0.41gm/dL), four (22.22%) with low alkaline phosphatase (20.50±11.83U/L), six (33.33%) with high alanine aminotransferase (136.66±37U/l)., and ten (55.56%) with high aspartate aminotransferase (238.60±39.15IU/L).
Conclusions: malignancy of disease and chemotherapy treatment negatively affected biochemical levels included in this study, liver function, and nutritional status of patients. 
PRECAUTIONARY MEASURES ARE TAKEN BY COUNTRIES TO REDUCE THE TRANSMISSION OF THE COVID-19
Get PDFTo limit the spread of COVID-19, the governments advise avoiding all non-essential travel outside until further notice. Aim: This review study aimed to find out the precautionary measures taken by governments to reduce transmission of the SARS-CoV-2 outbreak. Such countries have either suspended visas or do not allow visitors from infected countries to enter. Many airlines are suspending flights. Many airports are closing, preventing flights from leaving. Exit bans are becoming more frequent. The instructions that the European Union followed when the restriction should be lifted from countries that adhere to the standards set by member states together, including health status, ability to apply containment measures while traveling, and reciprocity considerations, keeping in mind the relevant data emanating from ECDC and WHO
PHARMACOLOGICAL AND ANTI CANCER ACTIVITY OF Ipomoea sepiaria METHANOLIC EXTRACT AGAINST PC-3 CELL LINE
Get PDFA few conventional restorative plants contain in explored concerning their enemy of corpulence likely wellsprings of is Ipomoea sepiaria Koenig ex. Roxb. The medicine is supposed in tales game plan of prescription for various accommodating properties like, love elixir and arsenic hurting, tonic, re-establishing, diuretic, laxative, uterotonic and sterility in women and leaves is shown particularly in diabetes. Phytochemical screening of different concentrates of Ipomoea sepiaria exposed the presence and non-attendance of various phytochemicals are available in ethanol remove, further examinations were done with leaves of Ipomoea sepiaria ethanol separate. PC3 (PC-3) is a human prostate malignancy cell lines that are profoundly utilized in examining the biochemical changes prostatic disease cells. Explores on PC-3 human prostate malignancy cell lines control are required in the current many years. The anticancer action of fluid concentrate of Ipomoea sepiaria was researched by 3-(4,5-dimethylthiazol-2-yl)- 2, 5-diphenyltetrazolium (MTT) measure utilizing PC-3 cell line. The current experimentation was indicated that watery concentrate of Ipomoea sepiaria, when exposed to various focuses on PC-3 cells demonstrated IC50 cell hindrance at about 5μM for 48 hours and about 2 μM for 72 hours. The information made by this particular examination gives relevant pharmacognostic and phytochemical data needed for proper distinctive confirmation and check of leaves of this particular species.
 
CHICKENPOX, REVIEW AND PREVALENCE VARICELLA VIRUS IN NINEVEH PROVINCE
Get PDFChicken pox is a seasonal, highly contagious disease caused by varicella virus. This virus belongs to the herpesviridae family. Although its symptoms are mild, the attention is meager to prevent its dispersal. Varicella virus proportion is high in developing countries because of the rapid spread between students as a result of indirect contact with instruments and secretions of a patient, droplets and airborne diffusion of vesicular fluid.
Aim: This study aimed to find out the prevalence of Varicella in Nineveh province sectors from 2005-2018. Our statistical analysis was brought out from all sections of the province.
Results: In the last decade, the number of cases has been increased in Iraq due to lack of health awareness in addition to the lack of vaccine. To reduce number of infections, it is necessary to follow up the patients and detect the virus mutations.
Conclusion: Isolation of patients may decrease virus spreading. Moreover, using of the novel methods for diagnosis are more significant as well as assign of the clinical features
TRANSFER LEARNING METHOD FOR SLEEP STAGES CLASSIFICATION USING DIFFERENT DOMAIN
Get PDFSleep stages classification using the signal analysis includes electroencephalogram (EEG), Electrooculography (EOG), Electromyography (EMG), Photoplethysmogram (PPG), and electrocardiogram (ECG). In this study, the proposed method using transfer learning to sleep stages classification. First, we have used the PPG and ECG signals, because they are less complex. This signal has the least complexity, and in this article we used this signal for transitional learning. n this study, we extracted 52 features from two signals and prepared for the classification stage. This method includes two steps, (a) Train data PPG and Test data ECG, (b) Train data ECG and Test data PPG. Results proved that our method has acceptable reliability for classification. The accuracy of 95.25% and 94.63% has been reached