Indian Journal Of Clinical Practice
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Navigating Choices: A Questionnaire-based Study on Usage of Antiplatelet Therapies in Management of Acute Coronary Syndrome in India
Get PDFPercutaneous coronary intervention (PCI) is a common invasive cardiac procedure used to treat acute coronarysyndrome (ACS). The main objective of anticoagulant therapy in PCI is to minimize the risk of plaque rupture and decreasethe formation of blood clots. Understanding clinicians\u27 prescription patterns is crucial for optimizing treatment strategiesfor patients with ACS who have undergone PCI. Methods: It was a cross-sectional, questionnaire-based, noninterventionalstudy which included questionnaire responses from 136 cardiologists, regarding usage of antiplatelets in ACS management.Results: Ticagrelor and aspirin dual antiplatelet therapy (DAPT) is favored by 54% cardiologists in managing ACS patientswho have undergone PCI, regardless of the presence or absence of type 2 diabetes mellitus (T2DM). Further, 78% of theparticipants preferred long-term DAPT over short-term and medium-term alternatives. Forty percent respondents preferreda 1-month triple antithrombotic therapy (TAT) for PCI patients with atrial fibrillation. Additionally, the study emphasizedthe importance of considering factors like age, bleeding history, hemoglobin, and creatinine clearance in determining theoptimal antithrombotic strategy. Conclusion: This study contributes valuable insights into the real-world practices of healthcare practitioners, paving the way for more informed and personalized ACS management strategies in Indian patients
Role of Cranberry in Urinary Tract Infections
Get PDFUrinary tract infection (UTI), both symptomatic and asymptomatic, occurs very frequently in the population, especially amongpatients with diabetes. With the advent of newer medications such as sodium-glucose co-transporter 2 (SGLT2) inhibitors, thereis greater focus on this disease. Cranberry products have been used earlier in various forms as a natural remedy for this disease.Certain compounds like flavonoids, distinctive proanthocyanidins with prominent active ingredients like phenolic acid inhibitthe adherence of fibrillae of Escherichia coli to the urothelial cells lining the urinary bladder. This article takes a brief look atthe disease and the role of cranberry as a natural remedy for UTI
Sports-Statin Interaction: Ensuring Safe and Smart Synergy
Get PDFBoth sports (physical activity) and statins are recommended for the prevention and management of atherosclerotic cardiovasculardisease. The synergy that they create in risk reduction, however, may turn dysfunctional at times. Statin usage is associated witha risk of muscle-related conditions including myalgia, myositis and rhabdomyolysis. This risk is exacerbated by unaccustomedphysical activity, exercise or sports. The communication shares practical and pragmatic suggestions regarding the preventionand management of the potential sports-statin interactions that may occur. It also highlights the need to consider drug-lifestyleinteractions, apart from conventional drug-drug interactions
A Rare Relapse of Kikuchi-Fujimoto Disease from Tertiary Care Hospital in Southern Rajasthan
Get PDFKikuchi-Fujimoto disease (KFD), also known as histiocytic necrotizing lymphadenitis, is a rare condition of unknown etiology presenting with cervical lymphadenopathy along with associated symptoms of fever, weight loss. It is often misdiagnosed due to rare existence. We report a case of a 21-year-old female who presented with painful cervical lymphadenopathy and low-grade fever on and off for 6 months. Examination revealed left-sided multiple, tender, matted lymph nodes measuring maximum 2 cm in size, firm and mobile. Patient underwent a panel of investigations including cervical biopsy, which revealed findings of KFD