Revista Jurídica Digital UANDES
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Red-Green-Go! A Self-Organising Game for Teaching Test-Driven Development
No full textTeaching test driven development (TDD) in an already crowded undergraduatecurriculum presents a number of challenges. How can we achieve deepunderstanding of the technique in a limited number of hours, in large classes, with extremely varying programming ability amongst the students and even with wide variations in the prior experience of students with TDD itself? We describe how we have applied a range of agile practices in the design of Red-Green-Go!—a board game for learning TDD that allows students to tailor the learning experience to suit their own level of experience and skill. After unsatisfactory attempts to use traditional teaching methods in our TDD classes, we made use of self-organising teams, big visible charts, frequent feedback and reflection to create a self-paced teaching activity. The game board guides pairs of students through the TDD cycle, as well as introducing students to different pair-coding styles. Feedback is available in various forms, including “community chest” style hint cards, with more extensive explanations and examples on a GitHub wiki for those that need them. Further scaffolding is provided by full worked examples. As well as describing the agile principles and practices used in the design of the game, we present an experience report from its use over 3 years, with cohorts of up to 100 students per year. We also reflect on the approach we took as a general technique for maximising learning amongst large student groups with widely varying levels of knowledge, experience and skills
Whole exome sequencing study to detect germline pathogenic variants in PALB2 and other cancer-predisposing genes in CDH1 mutation negative diffuse gastric cancer families.
No full textBackground: Germline pathogenic variants in the E-cadherin gene (CDH1) are strongly associated with the development of hereditary diffuse gastric cancer (HDGC) syndrome. The risk assessment and management of HDGC families that do not carry a CDH1 variant is limited. It is therefore difficult for such families to make informed choices about surveillance and risk reducing surgery. This study aimed to identify new candidate genes for HDGC predisposition in families with no detected pathogenic CDH1 variants (CDH1-NPV). Methods: Whole exome sequencing (WES) was performed on DNA extracted from blood obtained as part of the Familial Gastric Cancer Study. Analysis was performed across 39 individuals (28 affected and 11 unaffected) from 22 CDH1-NPV families that fulfil the international criteria for HDGC. Genes with loss-of-function variants were prioritised using gene interaction analysis to identify clusters of genes that could be involved in HDGC predisposition.Findings: Protein-affecting germline variants were identified in known cancer predisposition genes or lesser studied DNA repair genes in six HDGC families. A frameshift deletion within PALB2 was found in a family with a history of gastric and breast cancer. Two MSH2 variants were identified, one frameshift insertion and one previously described start loss, in unrelated affected individuals. One family was identified with a unique combination of variants in DNA repair genes ATR and NBN. A missense variant and a splice acceptor variant were seen in two unrelated families in DNA repair gene RECQL5.Interpretation: This study supports the role of known cancer predisposition gene PALB2 in the HDGC syndrome. It also puts forward new candidates in relation to HDGC risk within CDH1-NPV families.<br/
THE BOND BEHAVIOR BETWEEN C-FRCM COMPOSITE AND CONCRETE UNDER THE IMPRESSED CURRENT CATHODIC PROTECTION
No full textThis study investigates the feasibility of combining the impressed current cathodic protection (ICCP) as well as structural strengthening (SS) techniques for retrofitting reinforced concrete (RC) structures subjected to chloride-induced corrosion. In this ICCP-SS system, a dual-functional material, the carbon - fiber reinforced cementitious matrix (C-FRCM) composite, is used as both the anode and the strengthening material. The C-FRCM composite is consisted of a carbon fiber net (CF-NET) and a polymer-modified cementitious matrix. In order to evaluate the shear stress transfer behavior after ICCP, a series of specimens contained chloride ions were prepared for the single shear tests. Afterwards, impressed current cathodic protection (ICCP) was applied to the corroded specimens using different current densities for 60 days. Single shear tests were conducted after ICCP. The bond strengths and failure modes of the specimens subjected to cathodic protection were obtained. By comparing results, the effects of ICCP, especially some key parameters such as the current density and the electric quantity, on the shear stress transfer behavior was assessed. It is found that for the RC structures subjected to chloride-induced corrosion, the C-FRCM composite is not only an appropriate anode for ICCP, but also an effective strengthening material for shear stress transfer. Therefore, the innovative ICCP-SS retrofitting technique is seen to be promising and will lead to an improvement with respect to structural durability
A Novel 3-Level Access Control (3LAC) Framework for Data Access in a Healthcare Cloud Context
No full textWhile the use of Personal Health Records (PHRs) in a cloud computing environment brings benefits, it also raises concerns. One of the major concerns is how to prevent patients’ data managed by a cloud provider (i.e., a third-party) from being revealed to unauthorised entities, including the cloud provider.One way to address this concern is to protect data by using an Attribute-Based Encryption (ABE) based solution, in which data is encrypted before it is uploaded to the cloud provider. As part of the solution, data is first encrypted by using a symmetric key, which is then protected by using a pair of keys: a public and aprivate key. The public key is used for encrypting the symmetric key, and the private key is used for decrypting the symmetric key. To access data, a user needs to acquire the private key. Existing work on controlling the access of PHRs in a cloud environment largely focuses on how to make the solutions more fine-grained or how to strike the balance between data access granularity and efficiency. However, there is little work on ensuring how to securely distribute a private key in an ABE based PHRs access control system. This paper addresses the issue by proposing a multi-level approach to private key distribution in a Ciphertext- Policy ABE (CP-ABE) based access control model. This multilevelapproach is inspired by our observation that patients’ data may not have the same level of sensitivity, and to optimise the trade-off between privacy protection and costs (i.e., computational and communication), the level of access control should be tailored based on the data sensitivity levels. We have implemented these ideas by designing and evaluating a Novel 3-Level Access Control Framework (3LAC) that combines the Shamir’s Secret Sharing scheme with a CP-ABE based access control model, in which to access more sensitive data a user needs to acquire more shares, and for the acquisition of each share, there is an authentication process. The results of the evaluation have demonstrated that the 3LAC Framework balances the performance according to the data sensitivity levels as compared with a fixed-level approach
A Review and Gap Analysis of Exploiting Aerodynamic Forces as a Means to Control Satellite Formation Flight
No full textAerodynamic Technologies for Earth Observation Missions in Very Low Earth Orbit
No full textFlying at VLEO has several advantages such as the increase of the resolution of images recorded by optical instruments, the increase of geospatial position accuracy, the improvement of the signal to noise ratio and the reduction of energy consumption by active payloads. However, the drag produced by the interaction of the atmospheric gas particles with the surfaces of the spacecraft requires an extended knowledge of orbital aerodynamics. The aim of this work is to carry out a study from the principles of orbital aerodynamics to the definition of requirements for a set of satellite platforms covering Earth Observation applications taking advantageof operating in Very Low Earth Orbit (VLEO) and making use of aerodynamic technologies. Four platform concepts were defined: optical coverage platforms, optical Very High Resolution (VHR) for high performance platforms, low cost optical VHR platforms and Synthetic Aperture Radar (SAR) platforms. In addition, the main orbit and attitude control operations to be done with these concepts were analyzed. A relation between the different mission concepts and the performances to be obtained with enhanced aerodynamics was established to identify which of the four platform concepts could perform as a commercial platform to guarantee the use for different applications
Real-time closed loop EEG systems with electrical, auditory and app based visual feedback
No full textExploring links between innovation and profitability in Georgia Manufacturers
No full textEncouraging innovation in manufacturing is of much interest in business and policy circles. One aspect of this emphasis on innovation is the assumption that innovation leads to tangible business outcomes that can sustain the competitiveness of industries and create jobs. This paper examines the relationship of product and process innovation with profitability and employment growth using a unique set of cross-sectional data from the Georgia Manufacturing Survey over three time periods: 2005, 2010, and 2016. The results failed to show a direct connection between innovation and firm performance in the 2010 and 2016 periods. One implication from the 2010 and 2016 results is that standard product and process improvements are not enough to achieve added financial benefits because manufacturers may be having difficulty appropriating profits from these innovation practices in today’s globally competitive climate. The results suggest a need for more nuanced measurement of innovation in associating it with business outcomes