Australasian Medical Journal
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Prevalence of Endocrine Disorders Among Down Syndrome Individuals in Ksa: A Cross-Sectional Study
Get PDFObjective: To determine the prevalence of endocrine disorders among individuals with Down Syndrome in KSA. Methods: This research employs a cross-sectional study design to investigate the prevalence of endocrine disorders among individuals with Down Syndrome in the Kingdom of Saudi Arabia (KSA). A cross-sectional approach allows us to collect data at a single point in time from a diverse group of participants, providing a snapshot of the prevalence and characteristics of endocrine disorders within the study population. Results: The study included 686 participants. The participants asked if they had a child with Down syndrome. Most of them answered no (n= 576, 84%) followed by yes (n= 110, 16%). The most frequent child age who has Down syndrome among study participants was 7-10 years (n= 45, 40.9%) followed by 3-6 years (n= 30, 27.3%). The most frequent child gender who has Down syndrome among study participants was female (n= 57, 51.8%) followed by male (n= 53, 48.2%). Father's educational level among study participants with most of them having a university (n= 82, 74.5%). Mother's educational level among study participants with most of them having a university (n= 77, 70%). Participants were asked if there was a first-degree relationship between the parents. There 55 had a first-degree relationship with (50%), and 55 didn’t have a first-degree relationship between parents with (50%). Participants were asked the female about two diseases polycystic ovary disease there were 12 had it (10.9%), 62 didn’t have it (56.4%), and the second disease was Turner syndrome 22 had it (20%) and 53 participants didn’t have it (47.3%). Conclusion: Study results showed that most of the study participants don’t have Down Syndrome according to the parent's answers. Half of the participants have a first-degree relationship between their parents. The most educational level for parents was the university
Clinical Correlation Between Back Pain and Osteoarthritis Among Adults: A Cross-Sectional Study
Get PDFObjective: To investigate the clinical correlation between back pain and the role of osteoarthritis in the etiology of this pain. Methods: This research employs a cross-sectional study design to investigate the clinical correlation between back pain and osteoarthritis in adults. Cross-sectional studies provide a snapshot of data at a specific time, making them suitable for assessing the prevalence and potential associations between variables of interest. Results: The study included 1106 participants. The most frequent age among them was 40-50 years (n= 486, 43.9%), followed by 18-28 years (n= 340, 30.7%). The most frequent gender among study participants was female (n= 560, 50.6%) followed by male (n= 546, 49.4%). The most frequent marital status among study participants was married (n= 702, 63.5%), followed by single (n= 353, 31.9%). The most frequent job among study participants was a government job (n= 480, 43.4%), followed by a private sector job (n= 177, 16%). Duration of suffering from back pain among study participants with most of them being 1 to 5 years (n= 505, 45.7%), followed by nothing (n= 373, 33.7%), and the least was 23 years and above (n= 13, 1.2%). Participants were asked about evaluating the impact of back pain on life. For personal care, the most frequent was (currently, I do not feel any pain) (n= 514, 46.5%). The severity of pain, the most frequent, was (I can usually take care of myself and do my own things without adding to my pain) (n= 923, 83.5%). The lift and move things, the most frequent was (I can lift heavy objects without it adding to my pain) (n= 524, 47.4%). The walking, the most frequent was (The pain does not prevent me from walking any distance) (n= 801, 72.4%). The Sitting, the most frequent was (I can sit in any chair for as long as I want) (n= 661, 59.8%). The stand-up, most frequent was (I can stay standing as long as I want without increasing my pain) (n= 523, 47.3%). For sleep, the most frequent answer was (My sleep is never disturbed by pain) (n= 611, 55.2%). The Social-life, most frequent was (My social life is normal and does not cause me more pain) (n= 860, 77.8%). Conclusion: The results of the study showed that most of the participants were married and taught in government jobs. The majority of them do not suffer from severe back pain that affects their lives. In addition, most of the study participants had good and effective communicatio
Prevalence And Risk Factors of Eye Allergies Among Adults In Ksa: A Cross-Sectional Study
Get PDFObjective: To determine the prevalence of eye allergies and associated risk factors among adults in KSA. Methods: This research employs a cross-sectional study design to assess the prevalence and risk factors of eye allergies among adults in the Kingdom of Saudi Arabia (KSA). A cross-sectional approach allows for the collection of data at a single point in time, providing a snapshot of the condition's status within the study population. Results: The study included 640 participants. The most frequent age among them was 18-28 years (n= 331, 51.7%), followed by 40-50 years (n= 139, 21.7%). The most frequent gender among study participants was female (n= 389, 60.8%) followed by male (n= 251, 39.2 The most frequent nationality among study participants was Saudi (n= 613, 95.8%) followed by non-Saudi (n= 27, 4.2%). The educational level among study participants with most of them being the university (n= 553, 86.4%) followed by the school (n= 85, 13.3%). The work nature among study participants with most of was inside the building. Participants were asked if they had an eye problem that affected their daily life. The most frequent answer was moderately (n= 309, 48.3%) followed by never (n= 271, 42.3%), and the least was a lot (n=60, 9.4%). Conclusion: The results of the study showed that most of the study participants are Saudis and most of them work inside the building. The majority have university education, and the largest percentage of participants are women. Most of the participants are non-smokers. Most study participants had good social communication
Mepolizumab efficacy in the treatment of patients with eosinophilic granulomatosis with polyangiitis – Case Report
Get PDFEosinophilic granulomatosis with polyangiitis (EGPA), is a rare necrotizing vasculitis predominantly involving small to medium size vessels with eosinophilia and necrotizing granulomatous inflammation involving the respiratory tract, mepolizumab is an anti-interleukin-5 monoclonal antibody that binds to interleukin-5 and stops it from interacting with its receptor on the surface of eosinophils. To demonstrate that, we present a case of young female known to have bronchial asthma and chronic sinusitis since childhood presented with shortness of breath, found to have EGPA, her condition deteriorated and finely she was treated with Mepolizumab, which showed that it has efficacy in treating patients with EGPA
Association between Serum Vitamin B12 Concentration and Obesity Among Adults in The Ksa
Get PDFObjective: To investigate the relationship between serum vitamin B12 levels and weight among the adult population in KSA. Methods: This research will employ a cross-sectional study design to investigate the association between serum vitamin B12 concentration and obesity among adults in the Kingdom of Saudi Arabia (KSA). Cross-sectional studies are suitable for examining relationships between variables within a specific population at a single point in time. The target population for this study includes all adult residents of the KSA aged 18 years and older. Results: The study included 869 participants. The most frequent weight among them was 51-65 kg (n= 255, 29.3%), followed by 66 -75 kg (n= 214, 24.6%). The most frequent height among study participants was 161-170 cm (n= 324, 37.3%) followed by 151-160 cm (n= 266, 30.6%). The most frequent body mass index (BMI) value among study participants was Normal 18.5-24.9 kg/m2 (n= 344, 39.6%), followed by overweight 25-29.9 kg/m2 (n= 281, 32.3%). Vitamin B12 varied among study participants, with most of them having a normal range (n= 319, 36.7%) followed by a low range (n= 117, 13.5%) and the least common high range (n= 23, 2.6%). On the other hand, among 410 participants, 47.2% did not know their vitamin B12 value. Wech may indicate a lack of knowledge about the topic. Figure 4 shows the vitamin B12 levels among study participants. Conclusion: Study results showed that most of the study participants do not know their vitamin B12 level and need to increase awareness, followed by those who have a normal vitamin B12 level. The most common BMI was the normal level. There was a relationship between vitamin B12 levels and obesity.
Syndrome of Irreversible Lithium Induced Neurotoxicity due to chronic Lithium Use (SILENT)-Effect on functional status-A case report.
Get PDFBackground: Lithium has been used as a mood stabilizer for over a century, it is still the first-line agent for bipolar disorder (1, 2). A Large proportion of patients on chronic lithium therapy experience at least one episode of toxicity during treatment given its narrow therapeutic window (3). Case Presentation: This is a case report of a 50-year-old female with bipolar affective disorder who developed the syndrome of irreversible lithium effectuated neurotoxicity (SILENT). The case presentation covers the clinical symptoms and signs of SILENT causing functional impairment which effects their mobility and activities of daily living. Conclusion: Given its rare presentation, it is important for clinicians to be aware of this syndrome and its devastating effects. Early rehabilitation measures may help with achieving some functional independence but would assist with community reintegration and quality of life, long term
Journal Thank you note
Get PDFI am pleased to present to you this latest issue of the year 2024. Australasian medical Journal was established in the year 2008 and ever since its inception; the Journal has been consistently publishing scholarly and systematic study findings at issue release frequency of twelve issues per year. All the published issues comprised a balanced article types that include the original research, reviews, case reports, case studies, letter to the editors, commentaries and opinions
