Journal Of Advanced Zoology
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Characterization of the Phytochemicals and Antioxidant Properties of Extracts From Wrightia Tinctoria R.Br.
Get PDFIn the present investigation, phytochemical screening of different extracts of Wrightia tinctoria has been tested by using standard procedures. The findings showed the presence of alkaloids, flavonoids, phenols, steroids, terpenoids and glucosides. Among the four solvents tested (aqueous, ethanol, N-hexane and ethyl acetate) ethanol extract of leaf showed the best result. The free radical scavenging activity of both the extract was measured by using the 1,1-diphenyl-2-picrylhydrazyl (DPPH) assay. The aqueous and ethanol extracts of Wrightia tinctoria leaf shows slightly different antioxidant activity. The remarkable activity showed by the plant is due to the synergic effect of active compounds present in it.Characterization of phytochemicals was done by using UV-Visible spectrophotometry, FTIR analysis and Thin layer chromatograph
Optimization Of Simultaneous Estimation Of Candesartan And Nifedipine In Combination Therapy For Hypertension Management: A Green HPLC Approach Using Design Of Experiment Methodology
Get PDFackground: Hypertension is a prevalent health condition with severe implications for cardiovascular health. Combination therapy involving Candesartan and Nifedipine has emerged as a promising approach for managing hypertension due to the synergistic effects of these medications.
Methods: This study aimed to develop a Design of Experiment (DoE) based Green High-Performance Liquid Chromatography (HPLC) method for the simultaneous estimation of Candesartan and Nifedipine in a combined dosage form. Reversed-phase HPLC was utilized with UV-Vis spectrophotometry for detection. DoE principles were applied to optimize chromatographic conditions, including pH, ethanol percentage in the mobile phase, and flow rate.
Results: Optimal chromatographic separation was achieved using a composite mobile phase comprising ethanol and potassium dihydrogen phosphate buffer (45:55, v/v) at pH 3.7, with a flow rate of 1 mL/min. Statistical analysis confirmed the significance of these parameters in achieving efficient separation. The developed method exhibited high precision, accuracy, and reliability across various validation parameters, including specificity, linearity, repeatability, and robustness.
Conclusion: The proposed DoE-based Green HPLC method offers a sustainable and efficient approach for the simultaneous estimation of Candesartan and Nifedipine in hypertension management. By integrating green chemistry principles with systematic method development, this method provides a reliable analytical tool for routine quality control purposes in pharmaceutical formulations containing these medicatio
AI Technology Is Revolutionizing Climate Change Mitigation: An Overview
Get PDFClimate change is a global problem that has a significant impact on human health and economic well-being. Artificial intelligence (AI) has been shown to have great potential in reducing the effects of climate change. This article tries to provide a basic overview of the relationship between AI and mitigating climate change, highlighting AI\u27s revolutionary potential in combating this pressing global issue. In particular, this article looks at how big data is essential to the success of climate action programs and how AI technologies may use these enormous databases to help develop more efficient mitigation measures for climate change and adapt to them. We have investigated novel methods for comprehending climate dynamics, maximizing renewable energy systems, enhancing climate resilience, and improving environmental justice via the use of AI technology
Diaspora In Indian Literature; Women Who Felt Isolated In The World Crisis
Get PDFWomen have always dreamt about being in different places and have a different perspective of everything, when the men had the compulsion of moving places women were left with no choices to live where. Most Indian women from lower communities were transported without any prior experience or knowledge. If the cases were increasing women wanted to show their potential and they wanted to show their presence in such places. Women started writing poetry\u27s to prove their potential ability to the outsiders. Most of the works of them were pointed towards how their lives were designed and how they differentiated amount each others, once they realised the worthy writings of themselves they had to convert all their sorrows and love into language which was pretty difficult for most of them. Their families used to read them and trash them since they thought the women\u27s job was to be in homes and take care of the families, majorly men were allowed to talk about their difficulties when women were seen down and their struggle was left out in the place. No captors we\u27re called upon for all of these reasons, why has women always frowned and looked down when the cases of men being narcissist are tuned in to the society to live among everyone. They raised families in unknown places and they had the courage to stand up for themselves and make change in the lives of their husbands by sacrificing their own. The letters and books are not just about them it is also about the situations and awareness of the place they stayed upon
Development And Formulation Of Drug-Loaded Hydrogel For Skin Regenerative Potential
Get PDFSkin injuries, whether due to trauma, burns, or chronic wounds, present a significant clinical challenge, highlighting the need for innovative regenerative therapies. This study focuses on the development and formulation of a drug-loaded hydrogel as a promising approach for skin regeneration. Hydrogel is designed to provide a supportive environment for cell proliferation, migration, and differentiation, while also delivering therapeutic agents to accelerate wound healing. Various biocompatible polymers and crosslinking methods are explored to optimize the hydrogel\u27s mechanical properties, biodegradability, and drug release kinetics. Additionally, the study investigates the efficacy of different drugs, growth factors, and bioactive molecules in promoting angiogenesis, collagen synthesis, and tissue remodeling within the hydrogel scaffold. The developed drug-loaded hydrogel holds great potential for addressing a wide range of skin injuries and advancing the field of regenerative dermatology.
In summary, hydrogels represent a promising avenue in skin regenerative medicine due to their unique properties that support tissue repair, drug delivery, and wound healing processes. Ongoing research continues to explore innovative applications of hydrogels to address challenges in skin regeneration and wound treatment effectively.
Integrating Eyeglass Camera And Ultrasonic Smart Cane With Enhanced Navigation For Blind
Get PDFThe integration of intelligent wearable aids is revolutionizing accessibility solutions for people with visual and hearing impairments. Advanced CNN algorithms allow these devices to accurately interpret the real-time environment. Ultrasonic cameras improve mobility and safety by detecting obstacles and providing important visual information to users. For people with visual impairments, this system alerts people to the presence and location of obstacles, allowing them to navigate safely. At the same time, the vibration detection mechanism provides tactile feedback for people with hearing impairments, ensuring inclusive accessibility. These devices analyze visual input and provide intuitive feedback, allowing users to independently and safely navigate their environments. Continuous learning capabilities allow adaptation to different environments and ensure effectiveness in different scenarios. This innovative approach represents a major advance in improving the quality of life for people with disabilities. The seamless integration of AI, CNN algorithms, and sensory technology highlights the transformative potential of assistive technology to promote independence and inclusio
The Impact Of Physical Activity On Cognition, Behavior, And Attention In Healthcare Students Of Delhi NCR
Get PDFAim: This explores the relationship between physical activity and various cognitive, behavioral, and attentional aspects among healthcare students in the Delhi National Capital Region (NCR). It synthesizes existing literature to highlight the significant benefits of regular physical activity on academic performance, mental well-being, and professional development among healthcare students.
Methodology: a comprehensive review of existing literature from peer-reviewed journals, databases, and relevant sources to examine the impact of physical activity on cognition, behavior, and attention in healthcare students of Delhi NCR. Studies encompassing diverse methodologies, including experimental, observational, and intervention-based designs.
Result: The subjects had to be cognitively unimpaired and at age 55+ (the age was set for 55+ years since within this paper people above 55 years old are included in the group of ‘older people’. Although this may seem illogical, as they mostly are active and working persons, their cognitive (learning) operations require approaches specific to this age group, i.e., adult learning.
Conclusion: The present study investigated the effects of a structured physical activity program on cognition, behavior, and attention among healthcare students in the Delhi National Capital Region (NCR)
Impact Of Behavior, Bowel Function And Quality Of Life In Patients With Cerebral Palsy Along With Afo.
Get PDFAim:Cerebral palsy (CP) is a neurological disorder characterized by impaired movement and posture, often accompanied by disturbances in sensation, cognition, communication, and behavior. It affects approximately 1 in 323 children in the United States, making it one of the most prevalent developmental disabilities.
Methodology: Participants will include individuals diagnosed with cerebral palsy, aged 5 to 18 years, who are prescribed AFOs for ambulatory support. Recruitment will be conducted through pediatric rehabilitation clinics and cerebral palsy support organizations.
Result:
Conclusion:The study has significant implications for clinical practice, emphasizing the importance of considering behavior, bowel function, and quality of life outcomes when prescribing AFOs for individuals with cerebral palsy
Emerging Infectious Diseases In Wildlife Bridging The Gap Between Ecology And Human Health
Get PDFThe interface between wildlife, human populations, and environmental health has never been more pertinent than in the current era, where emerging infectious diseases (EIDs) in wildlife present unprecedented challenges to biodiversity and public health. This paper explores the multifaceted impact of EIDs in wildlife, underscoring the intricate linkages between ecological changes and the health of both wildlife and humans. Through a detailed review of recent research trends, this study identifies significant advancements in understanding the transmission dynamics, host-pathogen interactions, and ecosystem alterations associated with EIDs [6]. The literature review reveals critical research gaps, including the need for comprehensive surveillance systems, predictive modeling of disease emergence, and the development of effective mitigation strategies that encompass wildlife conservation and public health objectives. Employing a multidisciplinary approach, this paper proposes innovative methodologies for investigating EIDs, emphasizing the integration of ecological modeling, genomic technologies, and socio-economic analysis. By analyzing data from diverse sources, we employ robust statistical and analytical techniques to unravel the complex patterns of EID spread and impact [1]. The discussion extends beyond the scientific realm, delving into the implications for conservation strategies, policy formulation, and global health governance. In conclusion, this paper not only synthesizes current findings but also charts a course for future research directions, advocating for a \u27One Health\u27 approach that bridges the gap between ecology and human health in addressing the challenge of emerging infectious diseases in wildlife
Comparative Study Of Hot Pack Along With Therapeutic Ultrasound And Exercise Verses Therapeutic Tecar Along With Myofacial Release And Exercise On Supraspinatus Tendinitis In Female
Get PDFBackground and objective: This study aimed to compare the efficacy of two treatment protocols for supraspinatus tendinitis in female patients: (1) hot pack combined with therapeutic ultrasound and exercise, and (2) therapeutic TECAR combined with myofascial release and exercise. The primary outcomes measured were pain reduction, improvement in range of motion (ROM), and functional recovery.
Methods: A randomized controlled trial was conducted with 60 female participants diagnosed with supraspinatus tendinitis, equally divided into two treatment groups. Group A received hot pack, therapeutic ultrasound, and exercise, while Group B received therapeutic TECAR, myofascial release, and exercise. Pain intensity was assessed using the Visual Analog Scale (VAS), ROM was measured for shoulder flexion, abduction, and external rotation, and functional recovery was evaluated using the Shoulder Pain and Disability Index (SPADI). Assessments were made at baseline, mid-point (three weeks), and post-treatment (six weeks).
Results: Both groups showed significant improvements in all measured outcomes. However, Group B demonstrated superior results across all parameters. At the mid-point and post-treatment assessments, Group B had significantly lower VAS scores compared to Group A, indicating greater pain reduction (p < 0.05). ROM improvements were also more pronounced in Group B, with significant differences in shoulder flexion, abduction, and external rotation (p < 0.05). Functional recovery, as measured by SPADI scores, was significantly better in Group B at both the mid-point and post-treatment evaluations (p < 0.05).
Conclusion: The combination of therapeutic TECAR and myofascial release with exercise proved to be more effective than hot pack and therapeutic ultrasound with exercise for managing supraspinatus tendinitis in female patients