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Back to the Moon - in situ Chemical Analysis on the Lunar Surface Using LIMS: Highlights of Analytical Sciences in Switzerland
No full textCOMSOL: Simulation Drives Understanding
Get PDFCOMSOL Multiphysics® is a general-purpose simulation software used in all fields of engineering, manufacturing, and scientific research. The software offers fully coupled multiphysics and singlephysics
modeling capabilities, simulation data management, and user-friendly tools for building simulation applications. Spread the value of simulation to your design teams, manufacturing departments, test labs, customers, and other collaborators by distributing your apps using COMSOL Compiler™ and COMSOL Server™. Add-on modules provide specialized functionality for chemical reaction engineering, fluid flow, heat transfer, electromagnetics, structural mechanics, and acoustics. Interfacing products are available for CAD and other third-party software
Spectroscopic Tools to Investigate the Electrochemical Doping Kinetics and Efficiency in Organic Semiconductors
Get PDFUnderstanding the electrochemical doping of organic semiconductors plays a crucial role in the current development of organic electronics. In this short review, we present how temperature- and time- dependent visible-near-infrared (Vis-NIR) spectro-electrochemistry and terahertz spectroscopy, combined with multivariate curve resolution analysis, can inform on the fundamental mechanisms governing the doping kinetics and efficiency of two archetypal semiconducting polymers (PEDOT and P3HT). We highlight the experimental procedures and data analysis performed to access (i) the thermodynamic parameters driving the extent and dynamics of electrochemical reactions in doped systems and (ii) how the density and nature of charged species (polarons, bipolarons) impact the charge carrier delocalization, effective THz mobility and hence short-range conductivity
Comparison of the Old and New - Novel Mechanisms of Action for Anti-coronavirus Nucleoside Analogues
Get PDFOver the past two and a half years the world has seen a desperate scramble to find a treatment for SARS-CoV-2 and COVID. In that regard, nucleosides have long served as the cornerstone to antiviral treatments due to their resemblance to the naturally occurring nucleosides that are involved in numerous biological processes. Unlike other viruses however, it was found early on during the search for drugs to treat SARS-1 and later MERS, that the coronaviruses possess a unique repair enzyme, an exonuclease (ExoN)[3] which rendered nucleoside analogues useless, thus negating their use.[4] During the current outbreak however, as both well-known and new nucleoside analogues were investigated or reinvestigated as a possible cure for SARS-CoV-2, several novel and/or lesser-known mechanisms of action were uncovered. This review briefly describes these mechanisms
Medicinal Chemistry of Oligonucleotide Drugs - Milestones of the Past and Visions for the Future
Get PDFThe oligonucleotide therapeutics field has blossomed in recent years, with thirteen approved drugs today and the promise of accelerated growth in coming years. Much of the progress in this field is due to advances in the medicinal chemistry of oligonucleotides,combined with a judicious choice of molecular targets and disease areas. In this perspective, we describe the growth of this new class of drugs highlighting selected milestones in oligonucleotide medicinal chemistry
Moving Colors: Chemical Education
No full textTo attract children\u27s interest in Chemistry, the youngSCS composed this easy science experiment about chromatography. It shows in a beautiful and simple way the science behind colors and explains a common laboratory technique. To best reach its target audience this experiment was published “Kaleio”, a Swiss girl’s magazine
