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The Trichobezoar Enigma: Untangling The Intricacies Of Rapunzel Syndrome
Get PDFRapunzel Syndrome is a rare manifestation of trichobezoar, characterized by the presence of hair strands extending beyond the stomach and into the duodenum. Trichobezoars typically develop in individuals with a history of trichotillomania, a compulsive behavioral disorder involving hair-pulling, combined with trichophagia, the ingestion of hair. While trichobezoars predominantly form within the stomach, their occurrence in the jejunum is infrequent. This condition is more commonly observed in adolescent females.
The formation of bezoars within the gastrointestinal tract is typically attributed to anatomical changes. However, in cases where no such anatomical abnormalities are present, psychiatric disorders like trichotillomania can lead to the development of trichobezoars in the stomach. In this case, a 14-year-old patient is diagnosed with trichotillomania. The patient was admitted to the hospital due to complaints of nausea, vomiting, abdominal pain, constipation, and weight loss. Upon examination, a substantial trichobezoar was discovered, completely filling the stomach, duodenum, and extending into the mid-portion of the jejunum, resulting in subacute obstruction
Photocatalytic degradation of phenolic pollutants by Nanocomposites: A systematic review and pooled analysis
Get PDFAll living things depend on water, which is a precious natural resource. Modern hydropower generation, industrial processes, and transportation increasingly rely significantly on water. Emerging contaminants are currently posing a serious threat to our environment and significantly damaging human health. To address these water-related problems, photocatalysis, one of the advanced oxidation processes, has drawn a lot of attention. The most common photocatalytic approach for the elimination of phenolic pollutants, which is one of the emerging pollutants in the aquatic environment, was determined through a systematic review of the scientific literature in the current study. Furthermore, It was thought about how independent variables like pollutant concentration, catalyst amount, radiation time, pH, and contact time might affect the process. Twelve research, all of which focused on phenolic contaminants, were included. In two studies, all 12 phenolic contaminants were eliminated. Most of the pollutants exhibited a degradation efficiency above 90%. The removal of organic contaminants from water can be accomplished with efficiency and effectiveness by using sophisticated photocatalytic treatment methods. However, the combined data support photocatalytic treatment procedures as a new technique in recent years for the removal of organic contaminants
Meningitis in HIV positive and negative patients: A comparative demographic profile.
Get PDFBackground: Meningitis is a serious infection in HIV patients claiming millions of lives across the world. Comparative studies of meningitis in HIV positive and negative patients are scarce. Methods: We performed a comparative study of the demographic features of meningitis in HIV positive [116] and HIV negative [218] patients at a tertiary hospital over a period of four years. Results: In HIV seropositive patients the percentage of women was lesser [29.6% vs. 42.5%], the proportion of students was lesser [4.8% vs.14%], but the proportion of professionals was higher [17.5% vs. 10.8%] when compared to HIV seronegative group. Even though Tuberculosis [82.6% vs. 68.5%] was the predominant organism causing meningitis in both the groups, Cryptococcosis [5.2% vs. 1%] was more common in the seropositive individuals. Conclusions: The study highlights the differences in the demographic profile of meningitis in a large cohort of HIV positive and HIV negative patients
Aspect of sleep quality amid undergraduate medical students in correlation with BMI.
Get PDFPurpose: This study aimed to assess the quality of sleep among medical undergraduates from different phases of the medical program using the Pittsburgh Sleep Quality Index (PSQI) and to study the association of body mass index (BMI) with the quality of sleep among them. Material and Methods: Sleep quality was assessed among 482 medical undergraduates using the PSQI. Students undergoing treatment for psychiatric illness, diabetes or hypertension, history of alcohol consumption, and smoking were excluded from the study. Obesity was ascertained by calculating the BMI and categorized into 2 groups of23.0 according to the World Health Organization (WHO) guidelines for the Asian population. The chi-square test was utilized to compare seven components of PSQI and sleep quality for different phases and BMI groups and SPSS 24 was used to compare the components and the global score. Results: Only 0.8% of the total sample classified their sleep as very bad whereas 69.5% classified themselves as fairly good sleepers. The study participants had an average sleep time of 7.06±1.26 hours. The sleep duration (p23 had daytime dysfunction every day. Conclusions: It is necessary to create awareness among medical undergraduates about the importance of good sleep hygiene which will help them to improve their academic performance
Caffey disease – A rare case report.
Get PDF8 month old male infant with localized swelling of the thigh, fever and irritability
Plant Derived Bioactive Compounds, Their Anti-Cancer Effects as an Alternative Target Treatment Strategy for Breast Cancer: An Updated Overview
Get PDFFor decades, cancer has been a major public health concern worldwide owing to its high mortality rate. Many therapeutic strategies have come up in the scientific world, but it\u27s pitiful to know that synthetic chemotherapeutic agents either cause adverse effects or cancer cells develop resistance to these agents. Plant-derived chemotherapeutic agents present a wide range of therapeutics and most are yet to be discovered. In the current review, we have discussed the tumoricidal properties of Mucuna pruriens (seed), Withania coagulans (berry), Anacyclus pyrethrum (rhizome), Arachis hypogea (leaf), Rhizaoma polygoni (root) and Terminalia chebula (fruit). We have also tried to summarize the latest research in cancer chemoprevention and treatment using the bioactive components from these natural plants. Pharmaceutical developmental challenges and opportunities in bringing the phytochemicals into the market are also explored. The authors wish to expand this research area not only for their scientific soundness, but also for their potential-yet-affordable druggability
Sigma-Metric Analysis to Evaluate Quality Management of Analytical Processes Using RCA and QGI in a Clinical Biochemistry Laboratory, South India
Get PDFIntroduction: This study aimed to identify laboratory errors at the earliest through Sigma-metric analysis and to evaluate quality management of analytical processes. Methods: Sigma-metrics and Quality Goal Indices (QGI) were calculated by harvesting the IQC and EQC data of an accredited laboratory for 31 biochemical parameters run on Roche Cobas6000 and e411. Those with Sigma 2 were further analysed by applying the various Westgard rules, as suggested. Results: Nearly 13 chemistry analytes showed world-class performance with Sigma \u3e 6 and most of the immunoassay parameters showed marginal performance with sigma \u3e 2 6. Sodium, Chloride, Total T4, Beta-HCG and TSH were found to have Sigma \u3c 2 indicating unacceptable performance. A significant improvement was observed in the Sigma-metrics analysis after performing the root cause analysis. Conclusion: Sigma-metric analyses the quality management of various analytical processes in biochemistry. The poor assay performance will be picked up by the Root cause analysis and Quality Goal Indices calculation. With the help of RCA and QGI, we plan to increase the resource management by decreasing the frequency of QC runs
A Comparative Study on Depression, Anxiety, Stress, and Psychological Wellbeing Among Orphan and Non-Orphan Adolescents
Get PDFBackground: Orphans, other vulnerable children, and adolescents living in institutions are more susceptible to developing behavioral and emotional problems because they lack the love and care of a family. The current study intends to investigate stress, anxiety, and depression in orphans living in the chosen orphanages in Mysuru, Karnataka. Methodology: Descriptive research methods were implemented in this research. A total of 200 adolescents made up the representative sample, including 100 orphans and 100 non-orphans. The data were taken from numerous orphanages and schools located in the city of Mysore. The samples were chosen using purposive sampling techniques. The level of depression, anxiety, and psychological well-being among orphans was examined using a standardized interview schedule. A structured interview schedule that includes socio-demographic factors, stress, depression, and anxiety as well as the Ryff psychological well-being questionnaire were the instruments used for data collection. The analysis of data was done using version SPSS, 24.00. Results: The majority of respondents (100%) belonged to 14-18 years of age, and most of the orphans had severe and extremely severe depression anxiety, and stress compared to non-orphans. And there is a significant difference between study variables among the orphan and non-orphan groups. Conclusion: While compared to non-orphans, orphan adolescents have a high level of Depression anxiety, and stress and a low level of psychological well-being. So, there is a need to provide intervention for orphans to improve their psychological well-being
