International Journal of Nutrology
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Nutritional Risk Screening (NRS 2002) as a tool to predict clinical outcomes in hospitalized patients: a literature review
Get PDFThe presence of malnutrition in hospitalized patients is prevalent and studies show its association with a higher incidence of complications, mortality, length of stay, costs, and increased frequency of hospital readmission. Routine use of simple tracking procedures is recommended. Nutritional screening detects individuals who are malnourished or at risk of developing malnutrition, and who can receive specific nutritional support. Nutritional Risk Screening (NRS 2002) is a nutritional screening method recommended by the European Society for Clinical and Metabolism (ESPEN) and identifies the risk of developing malnutrition in hospitalized patients. The aim of this paper is to review the literature on the NRS screening method (2002) and its relationship with clinical outcomes in hospitalized patients
Permeable gut syndrome, gluten, and autoimmune disease: an integrative review
Get PDFoai:ojs2.ijn.zotarellifilhoscientificworks.com:article/4Introduction: Leaky Bowel Syndrome or intestinal permeability is a gastrointestinal condition that affects many people. A leaky gut is a trigger for many changes like food allergies and intolerances, autoimmune diseases, colitis, Crohn's and celiac disease, inflammatory diseases, depression, insulin resistance and even cancer have been linked. Objective: To analyze basic information for a better understanding of this topic, from the functioning of the gastrointestinal tract, as the diseases that are associated with it, how the immune system responds to these injuries, the quality, and importance of proteins, and the consequence of this disorder to the body human. Methods: Conducted an integrative literature review. The Pubmed, Google Scholar, and Scielo databases were consulted. Results: The intestine is naturally permeable to many small molecules, so it can absorb vital nutrients. Regulating intestinal permeability is one of the most basic functions of the cells that make up the intestinal wall. But one factor calls our attention, what is the role of gluten in the development of this disease and the worsening of symptoms? Insensitive people, gluten can cause cells to release zonulin, a protein that can break the tight junctions of intestinal tissue. Other factors—such as infections, toxins, stress, and age—can also cause these joints to come apart. Once strong joints break, you have a leaky gut. Gluten, therefore, is the number one cause of this process. A person with a leaky intestine tends to be highly allergic and intolerant to foods and substances, and may or may not manifest intestinal discomfort such as gas and bloating. Conclusion: Based on the literature that supports this theme, it is considered that gluten is a possible villain in the intestinal tract and is related to many autoimmune diseases. Furthermore, as an interventional measure, it is necessary to reduce some carbohydrate-rich foods and the maintenance of the body's balance with specific diets and physical activities
Major approaches on the nutrition and gut microbiota to health skin: a systematic review
Get PDFIntroduction: In the scenario of dermatological diseases. All other cutaneous and subcutaneous diseases accounted for 0.124% of the total. In this sense, several predictors can influence the composition of the microbiome. The composition of the diet modulates the GM balance, influencing the inflammatory response. One of the first dermatoses in which the positive influence of the use of probiotics was perceived was atopic dermatitis bacteria are very important and, when the lesions worsen, an imbalance in the microbiota is detected. In psoriasis, the use of probiotics seems to help by reducing skin inflammation. Objective: To carry out a concise systematic review of the main relationships of the nutrition-gut microbiota-skin axis, highlighting the importance of nutrology and gut microbiota for dermatological health. Methods: The research was carried out from June 2021 to July 2021 and developed based on Scopus, PubMed, Science Direct, Scielo, and Google Scholar, following the Systematic Review-PRISMA rules. The quality of the studies was based on the GRADE instrument and the risk of bias was analyzed according to the Cochrane instrument. Results: It was found that in the context of the interaction of nutritional health, metabolism encompasses the interactions between diet, microbiota, and cellular enzymatic processes that generate the chemical pathways necessary to maintain life. For the understanding of the regulatory processes that involve the nutrition-gut microbiota-skin axis, chronic inflammation is a crucial factor for the development of autoimmune diseases. For example, pathological T cells residing in the skin of patients with psoriasis produce excess IL-17 in response to IL-23, triggering the production of pro-inflammatory mediators IL-1β, IL-6, IL-8, TNF- α, and keratinocyte chemoattractants. The interaction of hormonal, neuronal, and inflammatory signaling has a major impact on skin health. Conclusion: Several studies have scientifically demonstrated the important relationship between GM and adequate nutrition for the establishment of the nutrition-gut microbiota-skin axis, highlighting the management of dermatoses with probiotics and prebiotics, as well as changes in lifestyle
Medical nutrition therapeutic approach of non-alcoholic fatty liver: diet, nutraceuticals, phytotherapy and probiotics
Get PDFAlthough the genetic and pharmacological research of the non-alcoholic fatty liver disease (NAFLD), the commonest liver disease in the world, affecting more than a quarter of the population, shows a promising future, the non-pharmacological therapy continues to be an important approach of this concerning public health issue. The present study focused on the therapeutical potential of the diet and mainly the phytotherapy, nutraceuticals, and probiotics use, employing the literature review methodology by a selection of recent (last 5-10 years) national and international articles from the PubMed and Google Scholar databases. The conclusion was that the non-pharmacological medical nutrition approach could be considered as a first-line therapeutical option for NAFLD due to its low cost, few adverse effects, and a mainly positive impact on an individual's health and life quality
Gut microbiota related to nutrition and physical activity: an integrative review
Get PDFIntroduction: The gut microbiota (GM) is formed by millions of microorganisms present in the gastrointestinal tract, especially in the colon. This intestinal homeostasis can be triggered by the union of a good diet, and even recent studies have suggested that aerobic physical training can modify its composition. Objective: To analyze the influence of healthy eating added to the practice of physical exercise in changing the composition of the GM. Methods: The research was carried out with an exploratory, qualitative and bibliographic approach. A literature review that brings together important studies on the influence of physical exercise on GM. Results: Data collection for this literature review was carried out from March to September, using articles, in addition to trustworthy websites, with the following descriptors: gut microbiota, microbiota, intestinal flora, food, probiotics, and physical exercise. Conclusion: The training was efficient to change the GM composition in sedentary men, thus being able to minimize possible negative interferences of the sedentary pattern. Bacteria that reside in our body work with a commensalism strategy, where there are two different structures, the microorganism, and the individual's body, but both live together normally and thus work together to maintain the GM balance
Programming of obesity and pediatric metabolic syndromes: a review in light of epigenetic modulation
Get PDFObesity is a multifactorial health problem characterized by the excessive accumulation of fat in the body and affects approximately 338 million children and adolescents worldwide. For this reason, this study consisted of a literature review to investigate how the causes and treatments of pediatric obesity are being addressed in light of epigenetic modulation as a factor in metabolic programming. For this, preferentially original articles published in English between the years 2017 to 2021 in the PubMed and Scholar Google databases were searched using the epigenetics descriptors; epigenetic modulation; child obesity; metabolic syndrome, combined with each other. A total of 54,000 articles were returned to searches in PubMed and 16,107,000 in Scholar Google. Fewer than 500 studies jointly addressed epigenetics and aspects of obesity or metabolic syndromes in childhood. Only 14 works matched the search criteria. The most discussed epigenetic mechanism in the literature is DNA methylation, whose rates observed mainly in CpG islands of promoter regions in several genes contribute to the prevention and early diagnosis of obesity and other pediatric comorbidities even before birth, based on the correlation between the epigenetic marks, maternal and paternal health and anthropometric indices. Although experimental studies on infant metabolic programming are scarce, existing knowledge suggests that environmental, nutritional, and energy expenditure changes are capable of modulating the epigenome and reversing marks that induce susceptibility to metabolic comorbidities
Effects of functional foods in diabetic patients: a systematic review
Get PDFThe control of Type II Diabetes Mellitus is directly related to the dietary profile, so an adequate diet for this group of patients must be implemented as soon as possible. But what foods can we use to facilitate glycemic and insulin control? Therefore, this study aims to systematically review the literature on the effects of functional foods in diabetic patients. Method: Systematic review of randomized clinical trials published between 2014 and 2021. Using as descriptors: Diabetes Mellitus Type 2 (Diabetes Mellitus Type 2), Functional Food. Results: Of the 566 articles found, 65 articles were selected, which passed the PEDro scale of methodological quality, and 11 articles were included. Of which they addressed different functional foods and their effects on different variables in diabetic patients. It can be concluded that several foods have beneficial effects on glycemic and insulin control in diabetic patients. Still, as a benefit, they had side effects in controlling dyslipidemia, blood pressure, and BMI
The influence of diet patterns on Alzheimer’s risk: a concise systematic review
Get PDFAlzheimer's disease (AD) is a progressive neurodegenerative disorder responsible for the main cause of dementia, and the increasing worldwide prevalence of AD is a major public health concern. Studies suggest that diet and nutrition may be important modifiable risk factors for AD. In addition, intestinal microbial metabolites and their effects on host neurochemical changes can increase or decrease the risk of AD. The aim of this literature review article is to discuss the relationship between dietary patterns, foods, gut microbiota, micro and macronutrients, and cognitive disorders, especially Alzheimer's. The results show that the excessive generation and accumulation of reactive pro-oxidant species over time can damage proteins, lipids, carbohydrates, and nucleic acids. Over time, this oxidative stress can contribute to a variety of age-related degenerative diseases. Therefore, antioxidant foods and healthy eating patterns, such as the Mediterranean diet, can contribute to reducing oxidative stress and consequently reducing the risk of Alzheimer's
Changes in the nutritional profile of medicine students during the COVID-19 pandemic period and its correlation with anxiety: a prospective cross-sectional observational study
Get PDFIntroduction: Pandemics cause strong social, economic, and political impacts. Social isolation to reduce the virus’ impact and to retard the health system breakdown caused by SARS-Cov-2 have affected the population’s lifestyle, including medical students. Objective: Identity which impacts the daily meal plan has the COVID-19’s Pandemic caused in medical students; Correlate data obtained in different grades of the medical course and present the nutritional profile of the students, who attended the study. Methods: Survey realized in students of a private medical course in the São Paulo northwestern region, with a questionary containing open questions and tests, sent online in conjunction with the Term of Consent. This study was analyzed and approved by the Research Ethics Committee according to a substantiated opinion number 4.373.785, and obtaining the patient's consent through the Informed Consent Form. Results: 117 students, between the 1st and 4th grade of the course, have attended the following study, 75 female, 42 male, allocated in similar proportions in the 4 initial grades of the course, ages between 17 and 31 years old; Most of the students feel more anxiety (78,6%), associated with changes in the nutritional profile, with the increase of high-energy food, highlighted by the bigger propension of this group to the consumption of sweets and white-wheat pasta in the daily meal plan. It is important to notice that many other food groups have suffered an enhancement in consumption as well, such as legumes, dried meat, vegetal oil, olive oil, and greenery. Conclusion: The COVID-19 Pandemic brought impacts to the daily meal plan of the medical students, especially in the ones who feel more anxious. The enhancement of the daily consumption of food by the medical students is notable, in the most diverse food classifications. However, it is concluded in this study that it cannot be said that anxiety and/or self-declared stress is a risk factor for the increase in food consumption observed, as well as a pattern of its impacts on the students' food, cannot be defined
Dysbiosis and obesity: implications of the gut microbiota
Get PDFIntroduction: Obesity has been considered a public health crisis, contributing as a risk factor for several important chronic diseases and even death. Considering this fact, it is noteworthy that there is a fundamental relationship between the intestine and health, and this organ is considered by modern medicine as our second brain in the concept of intestinal permeability. Within the evaluation of the food process, effective nutritional absorption can be altered due to imbalances, such as malabsorption, drug-nutrient interaction, changes in mucosal permeability, and, consequently, an imbalance in the gut microbiota. Dysbiosis is characterized by these negative changes that occur in the intestine. In this sense, the present systematic review study sought to answer: What influences can the microbiota composition have on the metabolic syndrome and obesity process? Objective: To elucidate the relationship between the presence of intestinal dysbiosis in the pathogenesis of obesity. Methods: This is a bibliographic review work where the MEDLINE, PubMed, and SciELO databases were consulted using the following descriptors: Human gut microbiota, obesity, dysbiosis. Results and Conclusion: Based on the literature that supports this theme, it was possible to observe that in the obese population there is an increase in bacteria of the genus Firmicutes and a decrease in the genus Bacteriodetes, with the blocking of factors and proteins that regulate the homeostasis of the absorption of lipids and fatty acids being observed thus being able to alter the energy metabolism leading to a greater accumulation of adipose tissue