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Suicidal ideation and associated factors among university students: a cross-sectional study at an Italian university
No full textUniversity students are at increased risk of psychological distress, depression, anxiety, and reduced well-being. Within this context, suicidal ideation represents a critical outcome due to its strong association with suicide attempts and completed suicide. While international studies report substantial variability in the prevalence of suicidal ideation among students, Italian data remain limited, particularly regarding comprehensive analyses of associated sociodemographic, academic, and psychological factors.
The primary objective of this study is to estimate the prevalence of suicidal ideation among students aged 18–29 enrolled at the University of Verona. Secondary objectives are: (1) to examine associations between suicidal ideation and sociodemographic and academic characteristics; (2) to investigate associations between suicidal ideation and psychological variables, including distress, depressive and anxiety symptoms, and psychological well-being; and (3) to identify high-risk subgroups based on cumulative psychological vulnerability.
This study adopts a cross-sectional design based on data collected through an anonymous online survey administered to all eligible students aged 18–29 at the University of Verona. Suicidal ideation is assessed using item 9 of the Patient Health Questionnaire (PHQ-9), operationalized as a binary variable (score ≥1 vs. 0). Psychological distress, depression, anxiety, and well-being are measured using the Kessler-10 (K-10), PHQ-9 (with PHQ-8 used in regression analyses to avoid overlap), GAD-7, and WHO-5, respectively. Sociodemographic and academic variables are collected via ad-hoc questions. Descriptive analyses will estimate prevalence rates. Associations between suicidal ideation and explanatory variables will be examined using univariate and multivariable logistic regression models, reporting odds ratios (ORs) and 95% confidence intervals (CIs). Additionally, cumulative psychological vulnerability will be explored by stratifying students according to the number of psychological domains exceeding established clinical cut-offs.
The study has received approval from the Institutional Review Board of the University of Verona (n. 05.R1/2023). Results will inform targeted prevention and early intervention strategies within university settings and will be disseminated through peer-reviewed publications and conference presentation
Unpredictable socio-ecology, supernatural beliefs and normative decision-making in Mauritius
No full textApplication of Mass Spectrometry in GLP‑1 and Dual Incretin Therapeutics: A Scoping Review of Analytical, Clinical, and Structural Advances (2008–2025)
No full textBackground/Objectives: Glucagon-like peptide‑1 receptor agonists (GLP‑1 RAs) and dual incretin agonists, such as semaglutide and tirzepatide, have rapidly expanded beyond diabetes care into broader metabolic and societal contexts. At the same time, liquid chromatography–tandem mass spectrometry (LC‑MS/MS) and high‑resolution mass spectrometry (HRMS) have become essential for characterizing these peptide therapeutics. This scoping review aimed to map the application of mass spectrometry across the lifecycle of GLP‑1–based drugs, identify methodological trends, and highlight remaining knowledge gaps. Methods: A scoping review framework was used to capture heterogeneous evidence across analytical chemistry, pharmacology, and clinical re-search. Studies were eligible if they applied LC‑MS/MS or HRMS to GLP‑1 RAs or dual agonists in biological matrices or drug products. Using the Population–Concept–Context (PCC) structure, data were charted across analytical platforms, study aims, bi-ological matrices, and thematic domains spanning preclinical, clinical, structural, and societal investigations. Results: Twenty‑five sources published between 2008 and 2025 met the inclusion criteria. Early work focused on foundational pharmacokinetics and LC‑MS/MS quantification of GLP‑1 analogs. More recent studies incorporated HRMS, ion mobility, microfluidic chromatography, and automated peptide mapping to improve sensitivity, selectivity, and structural resolution. Clinical research focused on bioe-quivalence, perioperative safety, and expanding therapeutic use, while societal analyses documented rising public interest and evolving attitudes among healthcare profes-sionals. Structural and omics‑based studies provided insight into receptor engagement, biased agonism, and metabolic modulation. Conclusions: Mass spectrometry applica-tions in GLP‑1 research have advanced substantially, enabling deeper characterization of pharmacokinetics, molecular mechanisms, and clinical performance. Remaining gaps include long‑term safety assessment, standardization of digital methodologies, and integration of HRMS into regulatory frameworks. This review provides a foundation for future systematic evaluations and methodological development
Sorghum-derived peptides: a scoping review of bioactivity, mechanisms and applications
No full textThis scoping review aims to systemically map the breadth of evidence available on sorghum-derived peptides, characterise their reported bioactive properties, mechanisms of action and potential applications, to inform future research
The Moral Limits of Capitalism: Alternatives for Shared Prosperity
No full textThe Moral Limits of Capitalism: Alternatives for Shared Prosperity delves into the ethical dilemmas embedded in capitalist systems and explores viable alternatives for achieving a more equitable distribution of wealth and prosperity. Written by Prof. Dr. Yoesoep Edhie Rachmad, Ph.D., DBA, this book critiques the prevailing model of capitalism, examining how it often perpetuates inequality, exploitation, and environmental harm. By investigating philosophical, economic, and social perspectives, the author proposes alternative economic frameworks that emphasize shared prosperity, social justice, and sustainability. This work provides an insightful examination of the limits of capitalism, urging readers to consider a more compassionate and responsible approach to global economic systems. Published by The United Nations and The Education Training Centre in 2008, this book seeks to inspire reflection and action on the moral implications of economic structures in the modern world.
The background of The Moral Limits of Capitalism: Alternatives for Shared Prosperity stems from an increasing global awareness of the moral shortcomings of capitalism, particularly in its contemporary form. Prof. Dr. Yoesoep Edhie Rachmad, Ph.D., DBA, was motivated by the widening gap between the rich and the poor, the erosion of the environment, and the growing socio-economic divides that are deeply rooted in capitalist systems. The book was written with the intent to explore the moral boundaries of capitalist practices and to suggest more just and humane alternatives for achieving global prosperity.
In this book, the key concepts of "capitalism," "moral limits," and "shared prosperity" are defined and explored in depth. Prof. Dr. Yoesoep Edhie Rachmad, Ph.D., DBA, defines capitalism as an economic system centered on private ownership of the means of production and the pursuit of profit. The moral limits of capitalism are explored in terms of its impact on social justice, human dignity, and environmental sustainability. Shared prosperity is introduced as an alternative economic framework that prioritizes equitable growth, social welfare, and responsible stewardship of resources.
The writing of this book was deeply influenced by the growing realization that capitalism, while generating wealth, often fails to provide a fair distribution of its benefits. Prof. Dr. Yoesoep Edhie Rachmad, Ph.D., DBA, observed the social and environmental crises exacerbated by unchecked capitalism, such as wealth inequality, climate change, and the erosion of workers' rights. The author also noted the rising calls for more ethical business practices and sustainable development, which served as a foundation for exploring potential alternatives to the capitalist model.
The principles that guide this book are based on the belief that economic systems should serve humanity and the planet, rather than exploit them. Prof. Dr. Yoesoep Edhie Rachmad, Ph.D., DBA, emphasizes the importance of empathy, fairness, and sustainability in economic structures. The book advocates for ethical capitalism, which balances profit-making with the well-being of people and the environment, and for alternative economic models that aim to build a more inclusive and sustainable global economy.
Indicators discussed in this book include measures of economic inequality, environmental degradation, human well-being, and social justice. Prof. Dr. Yoesoep Edhie Rachmad, Ph.D., DBA, uses these indicators to evaluate the effectiveness of capitalist systems and the alternatives proposed within the book. These indicators are essential for assessing the moral outcomes of economic practices and for guiding the transition toward more ethical and equitable economic systems.
The operational variables explored in this book include economic factors such as income distribution, access to education and healthcare, and environmental sustainability. Prof. Dr. Yoesoep Edhie Rachmad, Ph.D., DBA, also considers variables related to corporate behavior, government policies, and global trade systems, examining how these forces shape the distribution of wealth and opportunity.
The key determinants that influenced the writing of this book include the ethical challenges posed by global capitalism, the historical evolution of capitalist systems, and the socio-political movements advocating for economic reform. Prof. Dr. Yoesoep Edhie Rachmad, Ph.D., DBA, also draws on global case studies, historical lessons, and philosophical teachings to analyze the fundamental flaws in capitalism and to explore viable alternatives.
The book proposes practical strategies for implementing alternative economic systems that emphasize shared prosperity. These strategies include fostering cooperative business models, promoting fair trade, ensuring social safety nets, and transitioning toward sustainable industries. Prof. Dr. Yoesoep Edhie Rachmad, Ph.D., DBA, outlines the role of governments, corporations, and individuals in advocating for and adopting these new approaches.
The challenges discussed in this book include resistance from entrenched capitalist interests, the political and economic power of multinational corporations, and the ideological belief in the superiority of capitalism. Prof. Dr. Yoesoep Edhie Rachmad, Ph.D., DBA, acknowledges the difficulty of shifting global economic systems but argues that significant change is necessary for a more just and sustainable future.
In conclusion, The Moral Limits of Capitalism: Alternatives for Shared Prosperity provides a compelling critique of the capitalist system while offering alternative frameworks for achieving equitable and sustainable development. Prof. Dr. Yoesoep Edhie Rachmad, Ph.D., DBA, calls for a global movement toward more ethical economic practices that prioritize human dignity, environmental preservation, and the well-being of future generations